a study of micro rna expression profiles in ischaemic stroke



Jane Wu Post-Transcriptional Gene Regulation. RNA Processing in Eukaryotes Jane Wu Post-Transcriptional Gene Regulation. RNA Processing in Eukaryotes Новинка

Jane Wu Post-Transcriptional Gene Regulation. RNA Processing in Eukaryotes

2174.26 руб.
Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry.
Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Новинка

Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives

12369.51 руб.
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
Gustavo Caetano-Anollés Evolutionary Genomics and Systems Biology Gustavo Caetano-Anollés Evolutionary Genomics and Systems Biology Новинка

Gustavo Caetano-Anollés Evolutionary Genomics and Systems Biology

12520.47 руб.
A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.
Robert Meyers A. RNA Regulation Robert Meyers A. RNA Regulation Новинка

Robert Meyers A. RNA Regulation

32046.04 руб.
Based on one of the leading encyclopedic resources in cell and molecular biology worldwide, this two-volume work contains more than 75% new content, not previously published in the Encyclopedia. All the other chapters have been carefully updated. The result is a comprehensive overview of the different functions of the various forms of RNA in living organisms, with each contributor carefully selected and an internationally recognized expert on his or her field. Special focus is on the different forms of expression regulation through RNA, with medical applications in the treatment of diseases – from cancers and immune responses to infections and aging – covered in detail. At least 45 of the 55 articles are new content previously not published in the Encyclopedia.
Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Новинка

Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development

10812.96 руб.
RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.
Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Новинка

Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives

12831.64 руб.
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
Reg Morris C. Psychological Management of Stroke Reg Morris C. Psychological Management of Stroke Новинка

Reg Morris C. Psychological Management of Stroke

9898.6 руб.
Psychological Management of Stroke presents a review and synthesis of the current theory and data relating to the assessment, treatment, and psychological aspects of stroke. Provides comprehensive reviews of evidence based practice relating to stroke Written by clinical psychologists working in stroke services Covers a broad range of psychological aspects, including fitness to drive, decision making, prevention of stroke, and involvement of carers and families Reviews and synthesizes new data across a wide range of areas relevant to stroke and the assessment, treatment, and care of stroke survivors and their families Represents a novel approach to the application of psychological theory and principles in the stroke field
Doyle Arthur Conan A Study in Scarlet Doyle Arthur Conan A Study in Scarlet Новинка

Doyle Arthur Conan A Study in Scarlet

510 руб.
A Study in Scarlet (first published in 1987) marks the first appearance of Sherlock Holmes and Dr. Watson, who would become two of the most famous characters in popular fiction. Although Conan Doyle wrote 56 short stories featuring Holmes, A Study in Scarlet is one of only four full-length novels in the original canon.
Doyle, Arthur Conan A Study in Scarlet Doyle, Arthur Conan A Study in Scarlet Новинка

Doyle, Arthur Conan A Study in Scarlet

278 руб.
A Study in Scarlet (first published in 1987) marks the first appearance of Sherlock Holmes and Dr. Watson, who would become two of the most famous characters in popular fiction. Although Conan Doyle wrote 56 short stories featuring Holmes, A Study in Scarlet is one of only four full-length novels in the original canon.
Rassoul Noorossana Statistical Analysis of Profile Monitoring Rassoul Noorossana Statistical Analysis of Profile Monitoring Новинка

Rassoul Noorossana Statistical Analysis of Profile Monitoring

9898.6 руб.
A one-of-a-kind presentation of the major achievements in statistical profile monitoring methods Statistical profile monitoring is an area of statistical quality control that is growing in significance for researchers and practitioners, specifically because of its range of applicability across various service and manufacturing settings. Comprised of contributions from renowned academicians and practitioners in the field, Statistical Analysis of Profile Monitoring presents the latest state-of-the-art research on the use of control charts to monitor process and product quality profiles. The book presents comprehensive coverage of profile monitoring definitions, techniques, models, and application examples, particularly in various areas of engineering and statistics. The book begins with an introduction to the concept of profile monitoring and its applications in practice. Subsequent chapters explore the fundamental concepts, methods, and issues related to statistical profile monitoring, with topics of coverage including: Simple and multiple linear profiles Binary response profiles Parametric and nonparametric nonlinear profiles Multivariate linear profiles monitoring Statistical process control for geometric specifications Correlation and autocorrelation in profiles Nonparametric profile monitoring Throughout the book, more than two dozen real-world case studies highlight the discussed topics along with innovative examples and applications of profile monitoring. Statistical Analysis of Profile Monitoring is an excellent book for courses on statistical quality control at the graduate level. It also serves as a valuable reference for quality engineers, researchers and anyone who works in monitoring and improving statistical processes.
Conan Doyle A. A Study in Scarlet & The Sigh of the Four Conan Doyle A. A Study in Scarlet & The Sigh of the Four Новинка

Conan Doyle A. A Study in Scarlet & The Sigh of the Four

231 руб.
"Doctor Watson, Mr Sherlock Holmes" - The most famous introduction in the history of crime fiction takes place in Arthur Conan Doyle's "A Study in Scarlet", bringing together Sherlock Holmes, the master of cience detection, and John H. Watson, the great ... .
Barrett Kevin M. Stroke Barrett Kevin M. Stroke Новинка

Barrett Kevin M. Stroke

7308.47 руб.
Stroke is a leading cause of disability and death Early and rapid diagnosis of stroke is essential for identifying the optimum treatment strategy. Recurrence can be prevented if the underlying mechanism is understood. The earlier appropriate rehabilitation programmes can be started, the better the chance of a strong recovery. Stroke provides the foundations for practice that will enhance your patient’s chances of recovery. The expert authors provide the evidence-based roadmap you need to provide the best bedside care including: Bedside evaluation of the stroke patient Neurovascular imaging Treatment of acute ischemic stroke and hemorrhagic stroke Diagnosis of stroke mechanism and secondary prevention Post stroke recovery Telemedicine for the acute stroke patient Clinical in approach, practical in execution, Stroke will help you diagnose and manage your patients more effectively.
Stevenson Robert Louis Dr Jekyll & Mr Hyde. The Merry Men & Other Stories Stevenson Robert Louis Dr Jekyll & Mr Hyde. The Merry Men & Other Stories Новинка

Stevenson Robert Louis Dr Jekyll & Mr Hyde. The Merry Men & Other Stories

366 руб.
In seeking to discover his inner self, the brilliant Dr Henry lekyll discovers a monster. First published to immediate acclaim in 1886, this mesmerising thriller is a terrifying study of the duality of man's nature, and it is the book which established Stevenson`s reputuation as a writer.Also included in this volume is Stevenson's 1887 collection of short stories, "The Merry Men and Other Tales and Fables"."The Merry Men" is a gripping Highland tale of shipwrecks and madness; "Markheim", the sinister study of the mind of a murderer; "Thrawn Janet", a spine-chilling tale of demonic possession; "Olalla", a study of degeneration and incipient vampirism in the Spanish mountains; "Will O' the Mill", a thought-provoking fable about a mountain inn-keeper; and "The Treasure of Franchard", a study of French bourgeois life.
Robert Meyers A. Systems Biology Robert Meyers A. Systems Biology Новинка

Robert Meyers A. Systems Biology

29012.18 руб.
Systems biology is a relatively new biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. Systems biology is the study of the interconnected aspect of molecular, cellular, tissue, whole animal and ecological processes, and comprises mathematical and mechanistic studies of dynamical, mesoscopic, open, spatiotemporally defined, nonlinear, complex systems that are far from thermodynamic equilibrium.
Shinill Kang Micro / Nano Replication. Processes and Applications Shinill Kang Micro / Nano Replication. Processes and Applications Новинка

Shinill Kang Micro / Nano Replication. Processes and Applications

9490.51 руб.
An introduction to micro and nano replication processes and applications Micro/Nano Replication: Processes and Applications provides an overview of the fundamentals, processes, and applications involved in micro and nano replication in the manufacturing of product parts. A major field of nanotechnology, the study of micro/nano replication is sure to become one of increasing importance as the construction of completely new devices based on innovative concepts and crafted at the molecular level increases. Designed to help the reader understand and learn to work with the growing number of tools for molding plastic components, the book covers the key topics related to replication, including patterning technology, the modification of mold surface properties, and much more. In addition, it addresses the strengths and weaknesses of different molding processes. With a strong focus not only on how micro/nano replication works, but also the broader implications for the industry, the book is packed with examples of real world applications. These are drawn from a variety of fields, including information storage devices, optoelectronic elements, optical communication, and biosensors, in order to provide a complete view of the importance of micro and nano processes. A valuable introduction to a new but fast-growing field, Micro/Nano Replication is an essential resource for anyone looking to get a head start on understanding this emerging discipline.
William Brock J. The Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides William Brock J. The Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides Новинка

William Brock J. The Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides

9673.78 руб.
A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives. The book: Provides a complete overview of nonclinical study organization, conduct, and reporting and describes the roles and responsibilities of a Study Director to manage an effective study Covers regulatory and scientific concepts, including international testing and Good Laboratory Practice (GLP), compliance with guidelines, and animal models Features a concluding chapter that compiles case studies / lessons learned from those that have served as a Study Director for many years Addresses the entire spectrum of nonclinical testing, making it applicable to those in the government, laboratories and those actively involved in in all sectors of industry
Albrecht Bindereif Handbook of RNA Biochemistry Albrecht Bindereif Handbook of RNA Biochemistry Новинка

Albrecht Bindereif Handbook of RNA Biochemistry

10757.34 руб.
The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.
Rosaldo Renato A Companion to Latina/o Studies Rosaldo Renato A Companion to Latina/o Studies Новинка

Rosaldo Renato A Companion to Latina/o Studies

4119.04 руб.
A Companion to Latina/o Studies is a collection of 40 original essays written by leading scholars in the field, dedicated to exploring the question of what 'Latino/a' is. Brings together in one volume a diverse range of original essays by established and emerging scholars in the field of Latina/o Studies Offers a timely reference to the issues, topics, and approaches to the study of US Latinos – now the largest minority population in the United States Explores the depth of creative scholarship in this field, including theories of latinisimo, immigration, political and economic perspectives, education, race/class/gender and sexuality, language, and religion Considers areas of broader concern, including history, identity, public representations, cultural expression and racialization (including African and Native American heritage).
Hacke Werner Cerebrovascular Ultrasound in Stroke Prevention and Treatment Hacke Werner Cerebrovascular Ultrasound in Stroke Prevention and Treatment Новинка

Hacke Werner Cerebrovascular Ultrasound in Stroke Prevention and Treatment

18121.43 руб.
Effective stroke therapy can be improved through real-time monitoring of the neurological and cardiovascular responses to treatment. This requires crucial knowledge on behalf of both the sonographer and stroke physician to make the best decisions for the patient so as to minimize the damage caused by the original stroke and the risk of further stroke. Cerebrovascular Ultrasound in Stroke Prevention and Treatment, Second Edition, takes a practical approach to the examination of patients, the interpretation of ultrasound studies and the application of cerebrovascular ultrasound in the development of management and treatment studies, assisting neurologists, radiologists, and ultrasonographers in stroke therapy.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

14397.9 руб.
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Li-He Zhang Medicinal Chemistry of Nucleic Acids Li-He Zhang Medicinal Chemistry of Nucleic Acids Новинка

Li-He Zhang Medicinal Chemistry of Nucleic Acids

12819.16 руб.
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids presents a thorough overview of nucleic acid chemistry—a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids—such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs—to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy. Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes: In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry A close look at a large range of current topics on nucleic acid chemistry and biology Essential information on the use of nucleic acid drugs to treat diseases like cancer A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research area Thorough in its approach and promising in its message, Medicinal Chemistry of Nucleic Acids probes the new domains of pharmaceutical research—and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.
Morton Stephen Terror and the Postcolonial. A Concise Companion Morton Stephen Terror and the Postcolonial. A Concise Companion Новинка

Morton Stephen Terror and the Postcolonial. A Concise Companion

11586.98 руб.
Terror and the Postcolonial is a major comparative study of terrorism and its representations in postcolonial theory, literature, and culture. A ground-breaking study addressing and theorizing the relationship between postcolonial studies, colonial history, and terrorism through a series of contemporary and historical case studies from various postcolonial contexts Critically analyzes the figuration of terrorism in a variety of postcolonial literary texts from South Asia, Africa, and the Middle East Raises the subject of terror as both an expression of globalization and a postcolonial product Features key essays by well-known theorists, such as Robert J. C. Young, Derek Gregory, and Achille Mbembe, and Vron Ware
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

14935.89 руб.
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Darius Dziuda M. Data Mining for Genomics and Proteomics. Analysis of Gene and Protein Expression Data Darius Dziuda M. Data Mining for Genomics and Proteomics. Analysis of Gene and Protein Expression Data Новинка

Darius Dziuda M. Data Mining for Genomics and Proteomics. Analysis of Gene and Protein Expression Data

8553.13 руб.
Data Mining for Genomics and Proteomics uses pragmatic examples and a complete case study to demonstrate step-by-step how biomedical studies can be used to maximize the chance of extracting new and useful biomedical knowledge from data. It is an excellent resource for students and professionals involved with gene or protein expression data in a variety of settings.
Артур Конан Дойл A Study in Scarlet Артур Конан Дойл A Study in Scarlet Новинка

Артур Конан Дойл A Study in Scarlet

0 руб.
In the debut of literature's most famous sleuth, a dead man is discovered in a bloodstained room in Brixton. The only clues are a wedding ring, a gold watch, a pocket edition of Boccaccio's Decameron, and a word scrawled in blood on the wall. With this investigation begins the partnership of Sherlock Holmes and Dr. Watson.
Saura Sahu C. Toxicology and Epigenetics Saura Sahu C. Toxicology and Epigenetics Новинка

Saura Sahu C. Toxicology and Epigenetics

19292.19 руб.
Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research. Topics covered include: environment, epigenetics and diseases DNA methylation and toxicogenomics chromatin at the intersection of disease and therapy epigenomic actions of environmental arsenicals environment, epigenetics and cardiovascular health toxicology, epigenetics and autoimmunity ocular epigenomics: potential sites of environmental impact in development and disease nuclear RNA silencing and related phenomena in animals epigenomics – impact for drug safety sciences methods of global epigenomic profiling transcriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government.
Tomomatsu E. Japanese Grammar: 20 Most Basic Points. Elementary Level / 20 Аспектов Грамматики Японского Языка Начального Уровня Tomomatsu E. Japanese Grammar: 20 Most Basic Points. Elementary Level / 20 Аспектов Грамматики Японского Языка Начального Уровня Новинка

Tomomatsu E. Japanese Grammar: 20 Most Basic Points. Elementary Level / 20 Аспектов Грамматики Японского Языка Начального Уровня

2447 руб.
Aimed at people who have completed study at the beginner level but are worried about moving on to the intermediate stage, this book helps in a short period of time to build up their confidence through reviewing and reinforcing what they have studied. Arranged so that grammatical items can be reviewed together in various usages, as opposed to individually, the learner can grasp the usage and sense of the form of the Japanese expression concerned. Comes with a translation in Chinese, English and Korean.
Study in Scarlet & Sign of the Four Study in Scarlet & Sign of the Four Новинка

Study in Scarlet & Sign of the Four

260 руб.
'Doctor Watson, Mr Sherlock Holmes' - The most famous introduction in the history of crime fiction takes place in Sir Arthur Conan Doyle's A Study in...
Tatiana Maksimenko Micro Markets Workbook. A Market Structure Approach to Microeconomic Analysis Tatiana Maksimenko Micro Markets Workbook. A Market Structure Approach to Microeconomic Analysis Новинка

Tatiana Maksimenko Micro Markets Workbook. A Market Structure Approach to Microeconomic Analysis

2589.79 руб.
A companion Workbook to the text Micro Markets Understanding how microeconomics affects the marketplace is essential for any investment professional, however most books simply address microeconomics in its pure theory-based form. Micro Markets helped bridge the gap between theory and practice by defining microeconomics in terms of real-world, market applications. Now, the Micro Markets Workbook offers you a chance to review the information found in the actual book and solidify your understanding of this discipline. In this study guide, microeconomic concepts are fully reviewed, along with how all of its relevant theory is applicable to today's markets. Helps you learn to perform dynamic microeconomic analysis in practice Tests your knowledge of the information addressed in Micro Markets, before you put it to work in real world situations Provides solutions to each chapter of the main book's practice problems If you want to gain a firm understanding of the information outlined in Micro Markets, the lessons within this Workbook can help you achieve this goal.
Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Новинка

Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi

16098.86 руб.
RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: Mechanisms, Barriers, and Analysis of RNAi Delivery Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective Bioconjugation of siRNA for Site Specifi c Delivery Nanoscale Delivery Systems for RNAi Environmentally-Responsive Delivery Systems for RNAi Light-sensitive RNAi Viral-Mediated Delivery of shRNA and miRNA RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease miRNA as therapeutic agents and targets Advanced Delivery and Therapeutic Applications of RNAi combines the essential aspects of developing RNAi therapeutics from bench to clinic, and is invaluable for researchers working on RNAi, drug discovery and delivery, biomedical engineering, biomaterials, molecular biology, and biotechnology.
Bonnie Miller-McLemore J. The Wiley Blackwell Companion to Practical Theology Bonnie Miller-McLemore J. The Wiley Blackwell Companion to Practical Theology Новинка

Bonnie Miller-McLemore J. The Wiley Blackwell Companion to Practical Theology

16643.4 руб.
Through a series of essays contributed by leading experts in the field, The Wiley-Blackwell Companion to Practical Theology presents an introduction to practical theology as a major area of Christian study and practice, including an overview of its key developments, themes, methods, and future directions. The first comprehensive reference work to provide a survey, description and analysis of practical theology as an area of study A range of leading scholars in the field provide original contributions on the major areas, issues, and figures in practical theology Reviews an extensive range of methods for studying theology in practice, along with sub-disciplines in theological education such as pastoral care and preaching Covers developments in the discipline in a range of global contexts and distinct Christian traditions Shows how practical theology is relevant to everyday life
Huo Dr. Dehong Micro-Cutting. Fundamentals and Applications Huo Dr. Dehong Micro-Cutting. Fundamentals and Applications Новинка

Huo Dr. Dehong Micro-Cutting. Fundamentals and Applications

12835.53 руб.
Micro-Cutting: Fundamentals and Applications comprehensively covers the state of the art research and engineering practice in micro/nano cutting: an area which is becoming increasingly important, especially in modern micro-manufacturing, ultraprecision manufacturing and high value manufacturing. This book provides basic theory, design and analysis of micro-toolings and machines, modelling methods and techniques, and integrated approaches for micro-cutting. The fundamental characteristics, modelling, simulation and optimization of micro/nano cutting processes are emphasized with particular reference to the predictabilty, producibility, repeatability and productivity of manufacturing at micro and nano scales. The fundamentals of micro/nano cutting are applied to a variety of machining processes including diamond turning, micromilling, micro/nano grinding/polishing, ultraprecision machining, and the design and implementation of micro/nano cutting process chains and micromachining systems. Key features • Contains contributions from leading global experts • Covers the fundamental theory of micro-cutting • Presents applications in a variety of machining processes • Includes examples of how to implement and apply micro-cutting for precision and micro-manufacturing Micro-Cutting: Fundamentals and Applications is an ideal reference for manufacturing engineers, production supervisors, tooling engineers, planning and application engineers, as well as machine tool designers. It is also a suitable textbook for postgraduate students in the areas of micro-manufacturing, micro-engineering and advanced manufacturing methods.
Charlie Rose Race and Social Change. A Quest, A Study, A Call to Action Charlie Rose Race and Social Change. A Quest, A Study, A Call to Action Новинка

Charlie Rose Race and Social Change. A Quest, A Study, A Call to Action

2470.91 руб.
A powerful study illuminates our nation's collective civic fault lines Recent events have turned the spotlight on the issue of race in modern America, and the current cultural climate calls out for more research, education, dialogue, and understanding. Race and Social Change: A Quest, A Study, A Call to Action focuses on a provocative social science experiment with the potential to address these needs. Through an analysis grounded in the perspectives of developmental psychology, adaptive leadership and complex systems theory, the inquiry at the heart of this book illuminates dynamics of race and social change in surprising and important ways. Author Max Klau explains how his own quest for insight into these matters led to the empirical study at the heart of this book, and he presents the results of years of research that integrate findings at the individual, group, and whole system levels of analysis. It's an effort to explore one of the most controversial and deeply divisive subject's in American civic life using the tools of social science and empiricism. Readers will: Review a long tradition of classic, provocative social science experiments and learn how the study presented here extends that tradition into new and unexplored territory Engage with findings from years of research that reveal insights into dynamics of race and social change unfolding simultaneously at the individual, group, and whole systems levels Encounter a call to action with implications for our own personal journeys and for national policy at this critical moment in American civic life At a moment when our nation is once again bitterly divided around matters at the heart of American civic life, Race and Social Change: A Quest, A Study, A Call to Action seeks to push our collective journey forward with insights that promise to promote insight, understanding, and healing.
Victoria Wapf The Disease of Chopin. A comprehensive study of a lifelong suffering Victoria Wapf The Disease of Chopin. A comprehensive study of a lifelong suffering Новинка

Victoria Wapf The Disease of Chopin. A comprehensive study of a lifelong suffering

480 руб.
The life of the Polish-French pianist and composer Frédéric Chopin (1810—1849) was, to a great extent, influenced by his disease. Nevertheless, the diagnosis and differential diagnoses of his suffering remain a matter of debates in numerous biographical studies on the composer’s life. This study shall conduct a systematization and overview of Chopin’s medical history, in an effort to outline pathways to his most probable diagnosis.
Mark Considine Contracting-out Welfare Services. Comparing National Policy Designs for Unemployment Assistance Mark Considine Contracting-out Welfare Services. Comparing National Policy Designs for Unemployment Assistance Новинка

Mark Considine Contracting-out Welfare Services. Comparing National Policy Designs for Unemployment Assistance

2621.03 руб.
Contracting-out Welfare Services focuses on the design and overhaul of welfare-to-work systems around the world in the light of the radical re-design of the welfare system; internationally based authors utilise a national/program case study, considering employment services policy and activation practices. International contributors bring a global comparative perspective to the subject Contributors are all experts in their field, who also draw on a much longer intellectual legacy Uses employment services as a case study to advance understanding in relation to a host of broader principles and concepts Each paper included within the text uses a national/program case study, and each considers employment services policy in general, and activation practices in particular
Daniel Strachman A. Getting Started in Hedge Funds. From Launching a Hedge Fund to New Regulation, the Use of Leverage, and Top Manager Profiles Daniel Strachman A. Getting Started in Hedge Funds. From Launching a Hedge Fund to New Regulation, the Use of Leverage, and Top Manager Profiles Новинка

Daniel Strachman A. Getting Started in Hedge Funds. From Launching a Hedge Fund to New Regulation, the Use of Leverage, and Top Manager Profiles

1293.28 руб.
The book on hedge fund basics, completely updated to reflect today’s post-crisis industry The hedge fund industry has been reeling in the wake of recent Ponzi schemes and insider trading scandals as well as the loss of billions of dollars in assets under management due to fund closures. Getting Started in Hedge Funds, Third Edition focuses on the current state of the industry; how hedge funds did or did not survive the subprime and subsequent credit crisis; and, what the future holds for investors. Getting Started in Hedge Funds, Third Edition also provides readers with a brief overview of the industry's history, and describes the inner-workings of these complex investment vehicles, including how to start a hedge fund, and what new regulations means for managers and investors. • Profiles 10 highly successful hedge fund managers • Addresses the Madoff scandal, as well as other lesser known Ponzi schemes, and analyzes the ripple effect felt throughout the industry as a result of these and other scandals Despite the performance of some of these funds in the last few years, hedge funds are here to stay. In this Third Edition, Getting Started in Hedge Funds, Strachman provides an updated «how-to» guide for investors interested in hedge funds in this era of «new normal.»
Daniel Strachman A. AARP Getting Started in Hedge Funds. From Launching a Hedge Fund to New Regulation, the Use of Leverage, and Top Manager Profiles Daniel Strachman A. AARP Getting Started in Hedge Funds. From Launching a Hedge Fund to New Regulation, the Use of Leverage, and Top Manager Profiles Новинка

Daniel Strachman A. AARP Getting Started in Hedge Funds. From Launching a Hedge Fund to New Regulation, the Use of Leverage, and Top Manager Profiles

1293.28 руб.
AARP Digital Editions offer you practical tips, proven solutions, and expert guidance. The hedge fund industry has been reeling in the wake of recent Ponzi schemes and insider trading scandals as well as the loss of billions of dollars in assets under management due to fund closures. Getting Started in Hedge Funds, Third Edition focuses on the current state of the industry; how hedge funds did or did not survive the subprime and subsequent credit crisis; and, what the future holds for investors. Getting Started in Hedge Funds, Third Edition also provides readers with a brief overview of the industry's history, and describes the inner-workings of these complex investment vehicles, including how to start a hedge fund, and what new regulations means for managers and investors. Profiles 10 highly successful hedge fund managers Addresses the Madoff scandal, as well as other lesser known Ponzi schemes, and analyzes the ripple effect felt throughout the industry as a result of these and other scandals Despite the performance of some of these funds in the last few years, hedge funds are here to stay. In this Third Edition, Getting Started in Hedge Funds, Strachman provides an updated «how-to» guide for investors interested in hedge funds in this era of «new normal.»
E. V. Shevchenko Pediatric stroke. Revascularization and reconstructive surgery in children with cerebrovascular disease E. V. Shevchenko Pediatric stroke. Revascularization and reconstructive surgery in children with cerebrovascular disease Новинка

E. V. Shevchenko Pediatric stroke. Revascularization and reconstructive surgery in children with cerebrovascular disease

490 руб.
This book is about pediatric stroke. The book represents the main literary information about the etiology, pathogenesis, clinical manifestations of pediatric stroke, methods of examination and tactics of conservative and surgical treatment cerebral ischemia in children and surgical treatment of acute and chronic cerebral ischemia in children.
Damien Boquet Medieval Sensibilities. A History of Emotions in the Middle Ages Damien Boquet Medieval Sensibilities. A History of Emotions in the Middle Ages Новинка

Damien Boquet Medieval Sensibilities. A History of Emotions in the Middle Ages

4534.57 руб.
What do we know of the emotional life of the Middle Ages? Though a long-neglected subject, a multitude of sources – spiritual and secular literature, iconography, chronicles, as well as theological and medical works – provide clues to the central role emotions played in medieval society. In this work, historians Damien Boquet and Piroska Nagy delve into a rich variety of texts and images to reveal the many and nuanced experiences of emotion during the Middle Ages – from the demonstrative shame of a saint to a nobleman's fear of embarrassment, from the enthusiasm of a crusading band to the fear of a town threatened by the approach of war or plague. Boquet and Nagy show how these outbursts of joy and pain, while universal expressions, must be understood within the specific context of medieval society. During the Middle Ages, a Christian model of affectivity was formed in the ‘laboratory’ of the monasteries, one which gradually seeped into wider society, interacting with the sensibilities of courtly culture and other forms of expression. Bouqet and Nagy bring a thousand years of history to life, demonstrating how the study of emotions in medieval society can also allow us to understand better our own social outlooks and customs.
Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration Новинка

Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration

12369.51 руб.
A much-needed primer on the use of laser flow cytometry for stem cell analysis Laser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods and staining procedures based on specific characteristics such as marker expression, cell size, drug transport, and efflux of the stem cells. Now, this book reviews these procedures, discusses the science behind them, and provides real-world examples to illustrate the usefulness of the methods. It brings together world-class experts in pathology, biophysics, immunology, and stem cell research, who draw upon their extensive experience with the methods and show examples of good data to help guide researchers in the right direction. Chapter coverage includes: Stem cell analysis and sorting using side population Flow cytometry in the study of proliferation and apoptosis Stem cell biology and application Identification and isolation of very small embryonic-like stem cells from murine and human specimens Hematopoietic stem cells—issues in enumeration Human embryonic stem cells: long-term culture and cardiovascular differentiation Limbal stem cells and corneal regeneration Flow cytometric sorting of spermatogonial stem cells Breast cancer stem cells Stem cell marker expression in cells from body cavity fluids This book is an essential resource for all graduate students, practitioners in developing countries, libraries and book repositories of universities and research institutions, and individual researchers. It is also of interest to laboratories engaged in stem cell research and use of stem cells for tissue regeneration, and to any organization dealing in stem cell and tissue regeneration research.
Peter Wagner The Greek Polis and the Invention of Democracy. A Politico-cultural Transformation and Its Interpretations Peter Wagner The Greek Polis and the Invention of Democracy. A Politico-cultural Transformation and Its Interpretations Новинка

Peter Wagner The Greek Polis and the Invention of Democracy. A Politico-cultural Transformation and Its Interpretations

11619.63 руб.
The Greek Polis and the Invention of Democracy presents a series of essays that trace the Greeks’ path to democracy and examine the connection between the Greek polis as a citizen state and democracy as well as the interaction between democracy and various forms of cultural expression from a comparative historical perspective and with special attention to the place of Greek democracy in political thought and debates about democracy throughout the centuries. Presents an original combination of a close synchronic and long diachronic examination of the Greek polis – city-states that gave rise to the first democratic system of government Offers a detailed study of the close interactionbetween democracy, society, and the arts in ancient Greece Places the invention of democracy in fifth-century bce Athens both in its broad social and cultural context and in the context of the re-emergence of democracy in the modern world Reveals the role Greek democracy played in the political and intellectual traditions that shaped modern democracy, and in the debates about democracy in modern social, political, and philosophical thought Written collaboratively by an international team of leading scholars in classics, ancient history, sociology, and political science
David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts Новинка

David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts

2174.26 руб.
Moral Struggle and Religious Ethics offers a comparative discussion of the challenges of living a moral religious life. This is illustrated with a study of two key thinkers, Bonaventure and Buddhaghosa, who influenced the development of moral thinking in Christianity and Buddhism respectively. Provides an important and original contribution to the comparative study and practice of religious ethics Moves away from a comparison of theories by discussing the shared human problem of moral weakness Offers an fresh approach with a comparison of the understanding of the problem of moral weakness between the two key thinkers, Bonaventure and Buddhaghosa Written by a highly respected academic in the dynamic and fast-growing field of comparative religious ethics
Beverly Chin How to Study for Success Beverly Chin How to Study for Success Новинка

Beverly Chin How to Study for Success

1162.98 руб.
Develop powerful study skills that will last a lifetime! When you have strong study habits, you learn more in class, get more out of your homework, and, best of all, have a much easier time completing any type of assignment. How to Study for Success lets you build those habits and master essential study skills that will help you become a better student. Filled with easy-to-follow advice, this hands-on guide includes 7 Keys to Success that will help you improve your school performance: * Get Ready to Study Now * Get Organized * Make the Most of Class Time * Make the Most of Home Study Time * Make the Most of Homework * Put Your Computer to Good Use * Go the Extra Mile So get ready to improve your school performance-and study for success!
Michael Church The Regulation of Peace River. A Case Study for River Management Michael Church The Regulation of Peace River. A Case Study for River Management Новинка

Michael Church The Regulation of Peace River. A Case Study for River Management

11619.63 руб.
This book presents a comprehensive overview of the first longitudinal study of the downstream response of a major river to the establishment of a large hydropower facility and dams. Peace River, a northward flowing boreal river in northwestern Canada was dammed in 1967 and the book describes the morphological response of the 1200 km downstream channel and the response of riparian vegetation to the change in flow regime over the first forty years of regulated flows. Beginning with a description of the effect of regulation on the flow and sediment regimes of the river, the book proceeds to study changes in downstream channel geometry on the main stem, on the lowermost course of tributaries, and on the hydraulic geometry, the overall morphology of the channel, and riparian vegetation succession. The river is subject to annual freeze-up and break-up, so a chapter is devoted to the ice regime of the river. A chapter compares the effects of two extraordinary post-regulation flood events. The penultimate chapter presents a prediction of the ultimate equilibrium form of the regulated river based on rational regime theory. An online database of all the main observations will provide invaluable material for advanced students of river hydraulics and geomorphology. This book carefully brings together a range of studies that have been previously inaccessible providing a rare and comprehensive analysis of the effects of a big dam on a river, a river that itself represents an example of the kind of system that is likely to receive considerable attention in the future from dam engineers and environmentalists. • An invaluable reference to river scientists, hydroelectric power developers, engineers and environmentalists • Focus on a northward flowing boreal river, a type that holds most of the remaining hydroelectric power potential in the Northern Hemisphere • Exceptional separation of water and sediment sources, permitting study of the isolated effect of manipulating one of the two major governing conditions of river processes and form • Unique example of water regulation and both natural and engineered flood flows • Detailed study of both morphological changes of the channel and of the riparian vegetation • Online data supplement including major data tables and numerous maps. Details of the main observations and provides material for problem study by advanced students of river hydraulics and geomorphology are provided
David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts Новинка

David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts

9520.1 руб.
Moral Struggle and Religious Ethics offers a comparative discussion of the challenges of living a moral religious life. This is illustrated with a study of two key thinkers, Bonaventure and Buddhaghosa, who influenced the development of moral thinking in Christianity and Buddhism respectively. Provides an important and original contribution to the comparative study and practice of religious ethics Moves away from a comparison of theories by discussing the shared human problem of moral weakness Offers an fresh approach with a comparison of the understanding of the problem of moral weakness between the two key thinkers, Bonaventure and Buddhaghosa Written by a highly respected academic in the dynamic and fast-growing field of comparative religious ethics
Erika Hoff Research Methods in Child Language. A Practical Guide Erika Hoff Research Methods in Child Language. A Practical Guide Новинка

Erika Hoff Research Methods in Child Language. A Practical Guide

2174.26 руб.
This is a comprehensive and accessible guide to the methods researchers use to study child language, written by experienced scholars in the study of language development. Presents a comprehensive survey of laboratory and naturalistic techniques used in the study of different domains of language, age ranges, and populations, and explains the questions addressed by each technique Presents new research methods, such as the use of functional Near Infrared Spectroscopy (fNIRS) to study the activity of the brain Expands on more traditional research methods such as collection, transcription, and coding of speech samples that have been transformed by new hardware and software
Frans J. de Bruijn Handbook of Molecular Microbial Ecology I. Metagenomics and Complementary Approaches Frans J. de Bruijn Handbook of Molecular Microbial Ecology I. Metagenomics and Complementary Approaches Новинка

Frans J. de Bruijn Handbook of Molecular Microbial Ecology I. Metagenomics and Complementary Approaches

25589.38 руб.
The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the first comprehensive two-volume reference to cover unculturable microorganisms in a large variety of habitats, which could not previously have been analyzed without metagenomic methodology. It features review articles as well as a large number of case studies, based largely on original publications and written by international experts. This first volume, Metagenomics and Complementary Approaches, covers such topics as: Background information on DNA reassociation and use of 16 rRNA and other DNA fingerprinting approaches Species designation in microbiology Metagenomics: Introduction to the basic tools with examples Consortia and databases Bioinformatics Computer-assisted analysis Complementary approaches—microarrays, metatranscriptomics, metaproteomics, metabolomics, and single cell analysis A special feature of this volume is the highlighting of the databases and computer programs used in each study; they are listed along with their sites in order to facilitate the computer-assisted analysis of the vast amount of data generated by metagenomic studies. Handbook of Molecular Microbial Ecology I is an invaluable reference for researchers in metagenomics, microbiology, and environmental microbiology; those working on the Human Microbiome Project; microbial geneticists; molecular microbial ecologists; and professionals in molecular microbiology and bioinformatics.
Dennis Lindley V. Understanding Uncertainty Dennis Lindley V. Understanding Uncertainty Новинка

Dennis Lindley V. Understanding Uncertainty

8923.18 руб.
Praise for the First Edition «…a reference for everyone who is interested in knowing and handling uncertainty.» —Journal of Applied Statistics The critically acclaimed First Edition of Understanding Uncertainty provided a study of uncertainty addressed to scholars in all fields, showing that uncertainty could be measured by probability, and that probability obeyed three basic rules that enabled uncertainty to be handled sensibly in everyday life. These ideas were extended to embrace the scientific method and to show how decisions, containing an uncertain element, could be rationally made. Featuring new material, the Revised Edition remains the go-to guide for uncertainty and decision making, providing further applications at an accessible level including: A critical study of transitivity, a basic concept in probability A discussion of how the failure of the financial sector to use the proper approach to uncertainty may have contributed to the recent recession A consideration of betting, showing that a bookmaker's odds are not expressions of probability Applications of the book’s thesis to statistics A demonstration that some techniques currently popular in statistics, like significance tests, may be unsound, even seriously misleading, because they violate the rules of probability Understanding Uncertainty, Revised Edition is ideal for students studying probability or statistics and for anyone interested in one of the most fascinating and vibrant fields of study in contemporary science and mathematics.
Hugh McKenna The Delphi Technique in Nursing and Health Research Hugh McKenna The Delphi Technique in Nursing and Health Research Новинка

Hugh McKenna The Delphi Technique in Nursing and Health Research

4048.23 руб.
The Delphi Technique in Nursing and Health Research is a practical guide to using the Delphi methodology for students and researchers in nursing and health. It adopts a logical step-by-step approach, introducing the researcher to the Delphi, outlining its development, analysing key characteristics and parameters for its successful use and exploring its applications in nursing and health. The book addresses issues of methodology, design, framing the research question, sampling, instrumentation, methodological rigour, reliability and validity, and methods of data analysis. The Delphi Technique in Nursing and Health Research enables the reader to be aware of the limitations of the technique and possible solutions, to design a Delphi questionnaire for each of the different rounds of a study, to consider different approaches to the technique in relation to a study, to analyse the data from each round of a Delphi study, and to understand the importance of feedback between rounds. Key Features A practical guide to facilitate use of the Delphi technique Provides the reader with the necessary information to participate in and conduct Delphi studies Examines different types of Delphi, including the e-Delphi, and modifications made to the technique Includes examples of real empirical investigations, brief case scenarios and key learning points for each chapter Explores the role of the Delphi researcher Explores ethical issues and issues of anonymity, use of experts and controlled feedback
Jeffrey Rattiner H. Rattiner's Review for the CFP(R) Certification Examination, Fast Track Study Guide Jeffrey Rattiner H. Rattiner's Review for the CFP(R) Certification Examination, Fast Track Study Guide Новинка

Jeffrey Rattiner H. Rattiner's Review for the CFP(R) Certification Examination, Fast Track Study Guide

4663.58 руб.
A CFP® Study Guide that delivers what you need to succeed! This quick study guide for candidates preparing to take the CFP® Certification Examination covers the bare-bones essentials needed to pass this challenging exam in a logical and easy-to-absorb manner. Covering some of the most important disciplines of financial planning– insurance, employee benefit, investment, income tax, retirement, estate, and general planning– this text provides a no-nonsense approach to studying that includes: A highly logical and efficient format An in-depth outline of core essentials Explanations of all relevant exposures complete with solutions and practical examples Key points, exam tips, multiple choice, and mini—case study questions Mnemonic devices and study techniques to reinforce key points A format that directly parallels the CFP Board’s topic requirements and more! Order your copy today!
Michael Satlow The Gift in Antiquity Michael Satlow The Gift in Antiquity Новинка

Michael Satlow The Gift in Antiquity

9486.62 руб.
The Gift in Antiquity presents a collection of 14 original essays that apply French sociologist Marcel Mauss’s notion of gift-giving to the study of antiquity. • Features a collection of original essays that cover such wide-ranging topics as vows in the Hebrew Bible; ancient Greek wedding gifts; Hellenistic civic practices; Latin literature; Roman and Jewish burial practices; and Jewish and Christian religious gifts • Organizes essays around theoretical concerns rather than chronologically • Generates unique insights into gift-giving and reciprocity in antiquity • Takes an explicitly cross-cultural approach to the study of ancient history

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This book presents a comprehensive overview of the first longitudinal study of the downstream response of a major river to the establishment of a large hydropower facility and dams. Peace River, a northward flowing boreal river in northwestern Canada was dammed in 1967 and the book describes the morphological response of the 1200 km downstream channel and the response of riparian vegetation to the change in flow regime over the first forty years of regulated flows. Beginning with a description of the effect of regulation on the flow and sediment regimes of the river, the book proceeds to study changes in downstream channel geometry on the main stem, on the lowermost course of tributaries, and on the hydraulic geometry, the overall morphology of the channel, and riparian vegetation succession. The river is subject to annual freeze-up and break-up, so a chapter is devoted to the ice regime of the river. A chapter compares the effects of two extraordinary post-regulation flood events. The penultimate chapter presents a prediction of the ultimate equilibrium form of the regulated river based on rational regime theory. An online database of all the main observations will provide invaluable material for advanced students of river hydraulics and geomorphology. This book carefully brings together a range of studies that have been previously inaccessible providing a rare and comprehensive analysis of the effects of a big dam on a river, a river that itself represents an example of the kind of system that is likely to receive considerable attention in the future from dam engineers and environmentalists. • An invaluable reference to river scientists, hydroelectric power developers, engineers and environmentalists • Focus on a northward flowing boreal river, a type that holds most of the remaining hydroelectric power potential in the Northern Hemisphere • Exceptional separation of water and sediment sources, permitting study of the isolated effect of manipulating one of the two major governing conditions of river processes and form • Unique example of water regulation and both natural and engineered flood flows • Detailed study of both morphological changes of the channel and of the riparian vegetation • Online data supplement including major data tables and numerous maps. Details of the main observations and provides material for problem study by advanced students of river hydraulics and geomorphology are provided
Продажа a study of micro rna expression profiles in ischaemic stroke лучших цены всего мира
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