dna sequencing and gene cloning
T. A. Brown Gene Cloning and DNA Analysis. An Introduction
13871.59 руб.
Known world-wide as the standard introductory text to this important and exciting area, the seventh edition of Gene Cloning and DNA Analysis addresses new and growing areas of research whilst retaining the philosophy of the previous editions. Assuming the reader has little prior knowledge of the subject, its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented four-colour illustrations. In addition to a number of informative changes to the text throughout the book, the chapters on DNA sequencing and genome studies have been rewritten to reflect the continuing rapid developments in this area of DNA analysis: In depth description of the next generation sequencing methods and descriptions of their applications in studying genomes and transcriptomes New material on the use of ChiP-seq to locate protein-binding sites Extended coverage of the strategies used to assemble genome sequences Description of how the Neanderthal genome has been sequenced and what that sequence tells us about interbreeding between Neanderthals and Homo sapiens Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves. 
Wang Yongjun Gene Discovery for Disease Models
11724.7 руб.
This book provides readers with new paradigms on the mutation discovery in the post-genome era. The completion of human and other genome sequencing, along with other new technologies, such as mutation analysis and microarray, has dramatically accelerated the progress in positional cloning of genes from mutated models. In 2002, the Mouse Genome Sequencing Consortium stated that “The availability of an annotated mouse genome sequence now provides the most efficient tool yet in the gene hunter's toolkit. One can move directly from genetic mapping to identification of candidate genes, and the experimental process is reduced to PCR amplification and sequencing of exons and other conserved elements in the candidate interval. With this streamlined protocol, it is anticipated that many decades-old mouse mutants will be understood precisely at the DNA level in the near future.” The implication of such a statement should be similar to the identification of mutated genes from human diseases and animal models, when genome sequencing is completed for them. More than five years have passed, but genes in many human diseases and animal models have not yet been identified. In some cases, the identification of the mutated genes has been a bottleneck, because the genetic mechanism holds the key to understand the basis of the diseases. However, an integrative strategy, which is a combination of genetic mapping, genome resources, bioinformatics tools, and high throughput technologies, has been developed and tested. The classic paradigm of positional cloning has evolved with completely new concepts of genomic cloning and protocols. This book describes new concepts of gene discovery in the post-genome era and the use of streamlined protocols to identify genes of interest. This book helps identify not only large insertions/deletions but also single nucleotide mutations or polymorphisms that regulate quantitative trait loci (QTL). 
Nicholas Plant From Genes to Genomes. Concepts and Applications of DNA Technology
12368.4 руб.
The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation. The new edition features: Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics. Clear, two-colour diagrams throughout. A dedicated website including all figures. Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics. 
Martin Schleef Minicircle and Miniplasmid DNA Vectors. The Future of Non-viral and Viral Gene Transfer
11247.23 руб.
This first title on the topic provides complete coverage, including the molecular basis, production and possible biomedical applications. Written by the most prominent academic researchers in the field as well as by researchers at one of the world's leading companies in industrial production of minicircle DNA, this practical book is aimed at everyone who is directly or indirectly involved in the development of gene therapies. 
Gil Alterovitz Automation in Proteomics and Genomics. An Engineering Case-Based Approach
13197.18 руб.
In the last decade DNA sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools, technologies and process improvements. Further cost reductions in this and in related proteomics technologies are expected as a result of the development of new high-throughput techniques and the computational machinery needed to analyze data generated. Automation in Proteomics & Genomics: An Engineering Case-Based Approach describes the automation technology currently in the areas of analysis, design, and integration, as well as providing basic biology concepts behind proteomics and genomics. The book also discusses the current technological limitations that can be viewed as an emerging market rather than a research bottleneck. Topics covered include: molecular biology fundamentals: from ‘blueprint’ (DNA) to ‘task list’ (RNA) to ‘molecular machine’ (protein); proteomics methods and technologies; modelling protein networks and interactions analysis via automation: DNA sequencing; microarrays and other parallelization technologies; protein characterization and identification; protein interaction and gene regulatory networks design via automation: DNA synthesis; RNA by design; building protein libraries; synthetic networks integration: multiple modalities; computational and experimental methods; trends in automation for genomics and proteomics new enabling technologies and future applications Automation in Proteomics & Genomics: An Engineering Case-Based Approach is an essential guide to the current capabilities and challenges of high-throughput analysis of genes and proteins for bioinformaticians, engineers, chemists, and biologists interested in developing a cross-discipline problem-solving based approach to systems biology. 
Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors
11618.58 руб.
Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine. 
Li Yi Plant Gene Containment
12640.45 руб.
Gene Containment provides a comprehensive look at genetically modified organisms and the strategies and implementation of key methods to gene containment. The book is divided into 5 parts: An Introduction that discusses the need for biotechnology and GMOs, Section 1 looks at the need for gene containment, Part II discusses varying strategies for gene containment, section III explores the assessment of gene containment approaches, and section IV covers the steps involved in implementing gene containment. Gene Containment will provide a thorough and up to date look at gene containment research and the needs for implementing new strategies in this arena. 
Paul Singleton Dictionary of DNA and Genome Technology
12368.4 руб.
DNA technology is evolving rapidly, with new methods and a fast-growing vocabulary. This unique dictionary offers current, detailed and accessible information on DNA technology to lecturers, researchers and students throughout the biomedical and related sciences. The third edition is a major update, with over 3000 references from mainstream journals and data from the very latest research – going well beyond the remit of most science dictionaries. It provides clear explanations of terms, techniques, and tests, including commercial systems, with detailed coverage of many important procedures and methods, and includes essay-style entries on many major topics to assist newcomers to the field. It covers topics relevant to medicine (diagnosis, genetic disorders, gene therapy); veterinary science; biotechnology; biochemistry; pharmaceutical science/drug development; molecular biology; microbiology; epidemiology; genomics; environmental science; plant science/agriculture; taxonomy; and forensic science. 
Harbers Matthias Tag-based Next Generation Sequencing
15782.36 руб.
Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequencing methods largely extended the use of tag-based approaches as the tag lengths perfectly match with the short read length of highly parallel sequencing reactions. Tag-based approaches will maintain their important role in life and biomedical science, because longer read lengths are often not required to obtain meaningful data for many applications. Whereas genome re-sequencing and de novo sequencing will benefit from ever more powerful sequencing methods, analytical applications can be performed by tag-based approaches, where the focus shifts from 'sequencing power' to better means of data analysis and visualization for common users. Today Next Generation Sequence data require powerful bioinformatics expertise that has to be converted into easy-to-use data analysis tools. The book's intention is to give an overview on recently developed tag-based approaches along with means of their data analysis together with introductions to Next-Generation Sequencing Methods, protocols and user guides to be an entry for scientists to tag-based approaches for Next Generation Sequencing. 
Ion Mandoiu Computational Methods for Next Generation Sequencing Data Analysis
8997.79 руб.
Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics. 
Dhammika Amaratunga Exploration and Analysis of DNA Microarray and Other High-Dimensional Data
9598.21 руб.
Praise for the First Edition “…extremely well written…a comprehensive and up-to-date overview of this important field.” – Journal of Environmental Quality Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to study patterns of gene activity. The new edition answers the need for an efficient outline of all phases of this revolutionary analytical technique, from preprocessing to the analysis stage. Utilizing research and experience from highly-qualified authors in fields of data analysis, Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition features: A new chapter on the interpretation of findings that includes a discussion of signatures and material on gene set analysis, including network analysis New topics of coverage including ABC clustering, biclustering, partial least squares, penalized methods, ensemble methods, and enriched ensemble methods Updated exercises to deepen knowledge of the presented material and provide readers with resources for further study The book is an ideal reference for scientists in biomedical and genomics research fields who analyze DNA microarrays and protein array data, as well as statisticians and bioinformatics practitioners. Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition is also a useful text for graduate-level courses on statistics, computational biology, and bioinformatics. 
Crichton M. Jurassic Park
1294 руб.
An astonishing technique for recovering and cloning dinosaur DNA has been discovered. Now humankind’s most thrilling fantasies have come true. Creatures extinct for eons roam Jurassic Park with their awesome presence and profound mystery, and all the world can visit them—for a price.Until something goes wrong.In Jurassic Park, Michael Crichton taps all his mesmerizing talent and scientific brilliance to create his most electrifying technothriller. 
Rene Kratz Fester Biology Essentials For Dummies
636.97 руб.
Just the core concepts you need to score high in your biology course Biology Essentials For Dummies focuses on just the core concepts you need to succeed in an introductory biology course. From identifying the structures and functions of plants and animals to grasping the crucial discoveries in evolutionary, reproductive, and ecological biology, this easy-to-follow guide lets you skip the suffering and score high at exam time. Get down to basics – master the fundamentals, from understanding what biologists study to how living things are classified The chemistry of life – find out what you need to know about atoms, elements, molecules, compounds, acids, bases, and more Conquer and divide – discover the ins and outs of asexual and sexual reproduction, including cell division and DNA replication Jump into the gene pool – grasp how proteins make traits happen, and easily understand DNA transcription, RNA processing, translation, and gene regulation Open the book and find: An overview of cells and their substructures Elementary chemistry The key facts about reproduction and DNA The 411 on energy and organisms What you need to know about evolution Coverage of ecosystems and populations Ten great biology discoveries Learn: Core concepts taught in an introductory biology course The structures and functions of plants and animals The key discoveries in evolutionary, reproductive, and ecological biology 
Murugan Ramalingam Biomedical Materials and Diagnostic Devices
18145.68 руб.
The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration. 
Robert A. Goodnow, Jr. A Handbook for DNA-Encoded Chemistry. Theory and Applications for Exploring Chemical Space and Drug Discovery
9672.91 руб.
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods 
Frans J. de Bruijn Handbook of Molecular Microbial Ecology I. Metagenomics and Complementary Approaches
25208.1 руб.
The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the first comprehensive two-volume reference to cover unculturable microorganisms in a large variety of habitats, which could not previously have been analyzed without metagenomic methodology. It features review articles as well as a large number of case studies, based largely on original publications and written by international experts. This first volume, Metagenomics and Complementary Approaches, covers such topics as: Background information on DNA reassociation and use of 16 rRNA and other DNA fingerprinting approaches Species designation in microbiology Metagenomics: Introduction to the basic tools with examples Consortia and databases Bioinformatics Computer-assisted analysis Complementary approaches—microarrays, metatranscriptomics, metaproteomics, metabolomics, and single cell analysis A special feature of this volume is the highlighting of the databases and computer programs used in each study; they are listed along with their sites in order to facilitate the computer-assisted analysis of the vast amount of data generated by metagenomic studies. Handbook of Molecular Microbial Ecology I is an invaluable reference for researchers in metagenomics, microbiology, and environmental microbiology; those working on the Human Microbiome Project; microbial geneticists; molecular microbial ecologists; and professionals in molecular microbiology and bioinformatics. 
Ashutosh Tiwari DNA Engineered Noble Metal Nanoparticles. Fundamentals and State-of-the-Art of Nanobiotechnology
16871.56 руб.
There is a growing interest in the use of nanoparticles modified with DNAs, viruses, peptides and proteins for the rational design of nanostructured functional materials and their use in biosensor applications. The challenge is to control the organization of biomolecules on nanoparticles while retaining their biological activity as potential chemical and gene therapeutics. These noble metal nanoparticles/biomolecules conjugates have specific properties and therefore they are attractive materials for nanotechnology in biochemistry and medicine. In this book, the author review work performed dealing with the DNA structure and functionalities, interactions between DNA, noble metal nanoparticles, surface active agents, solvents and other additives. Particular attention is given to how the DNA’s chain length and the DNA conformation affect the interaction and structure of the nanoconjugates and nanostructures that are formed. Also discussed are the recent advances in the preparation, characterization, and applications of noble metal nanoparticles that are conjugated with DNA aptamers and oligomers. The advantages and disadvantages of functionalized nanoparticles through various detection modes are highlighted, including colorimetry, fluorescence, electrochemistry, SPR, and, mass spectrometry for the detection of small molecules and biomolecules. The functionalized noble metal nanoparticles are selective and sensitive for the analytes, showing their great potential in biosensing. Furthermore, this book reviews recent progress in the area of DNA-noble metal nanoparticles based artificial nanostructures, that is, the preparation, collective properties, and applications of various DNA-based nanostructures are also described. 
Eugen Stulz DNA in Supramolecular Chemistry and Nanotechnology
12292.99 руб.
This book covers the emerging topic of DNA nanotechnology and DNA supramolecular chemistry in its broader sense. By taking DNA out of its biological role, this biomolecule has become a very versatile building block in materials chemistry, supramolecular chemistry and bio-nanotechnology. Many novel structures have been realized in the past decade, which are now being used to create molecular machines, drug delivery systems, diagnosis platforms or potential electronic devices. The book combines many aspects of DNA nanotechnology, including formation of functional structures based on covalent and non-covalent systems, DNA origami, DNA based switches, DNA machines, and alternative structures and templates. This broad coverage is very appealing since it combines both the synthesis of modified DNA as well as designer concepts to successfully plan and make DNA nanostructures. Contributing authors have provided first a general introduction for the non-specialist reader, followed by a more in-depth analysis and presentation of their topic. In this way the book is attractive and useful for both the non-specialist who would like to have an overview of the topic, as well as the specialist reader who requires more information and inspiration to foster their own research. 
Босоножки Gene Gene GE632AWEMIR2
2530 руб.
Босоножки Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Сандалии Gene Gene GE632AWEMIT6
1720 руб.
Сандалии Gene. Цвет: серебряный. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Сабо Gene Gene GE632AWEMIS6
2030 руб.
Сабо Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Сабо Gene Gene GE632AWEMIS8
2460 руб.
Сабо Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Сандалии Gene Gene GE632AWEMIT4
2590 руб.
Сандалии Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Сабо Gene Gene GE632AWEMIT2
1670 руб.
Сабо Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Полусапоги Gene Gene GE632AWCMWR3
3700 руб.
Полусапоги Gene. Цвет: черный. Материал: искусственный велюр, искусственный мех.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Кроссовки Gene Gene GE632AWEMIS1
2920 руб.
Кроссовки Gene. Цвет: розовый. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Сабо Gene Gene GE632AWAURX5
1750 руб.
Сабо Gene. Цвет: коричневый. Материал: искусственная лаковая кожа.Сезон: Весна-лето 2018. С бесплатной доставкой и примеркой на Lamoda. 
Дутики Gene Gene GE632AWGBGN4
4850 руб.
Дутики Gene. Цвет: коричневый. Материал: текстиль.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Сабо Gene Gene GE632AWEMIS7
2840 руб.
Сабо Gene. Цвет: черный. Материал: искусственная замша.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Слипоны Gene Gene GE632AWEMIU0
1750 руб.
Слипоны Gene. Цвет: черный. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIU2
2330 руб.
Туфли Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Кроссовки Gene Gene GE632AWEMIR8
2980 руб.
Кроссовки Gene. Цвет: коричневый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Кроссовки Gene Gene GE632AWGAVI0
4999 руб.
Кроссовки Gene. Цвет: черный. Материал: искусственная замша.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIV1
2270 руб.
Туфли Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIU9
2150 руб.
Туфли Gene. Цвет: розовый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Полусапоги Gene Gene GE632AWGBGN7
4240 руб.
Полусапоги Gene. Цвет: черный. Материал: искусственная замша.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Ботфорты Gene Gene GE632AWGBGM5
4310 руб.
Ботфорты Gene. Цвет: черный. Материал: искусственная замша.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Ботильоны Gene Gene GE632AWGAVH8
2690 руб.
Ботильоны Gene. Цвет: бордовый. Материал: искусственная замша.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Дутики Gene Gene GE632AWGBGN2
4490 руб.
Дутики Gene. Цвет: черный. Материал: нейлон.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Dittmar Katharina Evolution after Gene Duplication
9345.27 руб.
Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity. Key Features: Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system) A complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways Taps the significant increase in multi-gene family data that has resulted from comparative genomics Comprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students. 
Сандалии Gene Gene GE632AWEMIT9
2200 руб.
Сандалии Gene. Цвет: белый. Материал: искусственная кожа, текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Босоножки Gene Gene GE632AWEMIQ7
2790 руб.
Босоножки Gene. Цвет: фиолетовый. Материал: искусственная замша.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Босоножки Gene Gene GE632AWEMIQ9
2400 руб.
Босоножки Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Босоножки Gene Gene GE632AWEMIR4
2920 руб.
Босоножки Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Дутики Gene Gene GE632AWCMWQ6
3840 руб.
Дутики Gene. Цвет: серый. Материал: текстиль.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Ботинки Gene Gene GE632AWCMWP2
4670 руб.
Ботинки Gene. Цвет: зеленый. Материал: искусственная замша.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Лоферы Gene Gene GE632AWEMIS2
3110 руб.
Лоферы Gene. Цвет: серый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Ботинки Gene Gene GE632AWGBGM3
5299 руб.
Ботинки Gene. Цвет: черный. Материал: искусственная замша, искусственная кожа.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWCMWR9
1590 руб.
Туфли Gene. Цвет: красный. Материал: искусственная лаковая кожа.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Дутики Gene Gene GE632AWGBGN5
4999 руб.
Дутики Gene. Цвет: черный. Материал: текстиль.Сезон: Осень-зима 2019/2020. С бесплатной доставкой и примеркой на Lamoda. 
Босоножки Gene Gene GE632AWEMIR0
2400 руб.
Босоножки Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIU3
2330 руб.
Туфли Gene. Цвет: розовый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIU8
2620 руб.
Туфли Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Босоножки Gene Gene GE632AWEMIT3
2720 руб.
Босоножки Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Босоножки Gene Gene GE632AWEMIR5
2920 руб.
Босоножки Gene. Цвет: серый. Материал: искусственная замша.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Дутики Gene Gene GE632AWCMWQ4
3130 руб.
Дутики Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Ботинки Gene Gene GE632AWCMWR0
3980 руб.
Ботинки Gene. Цвет: черный. Материал: искусственная замша, натуральный мех.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Ботинки Gene Gene GE632AWCMWR1
3910 руб.
Ботинки Gene. Цвет: синий. Материал: искусственная замша, искусственный мех.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIU6
1920 руб.
Туфли Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Туфли Gene Gene GE632AWEMIV0
2270 руб.
Туфли Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda. 
Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics.
