drosophila melanogaster an model system for toxicity studies



Patricia McGrath Zebrafish. Methods for Assessing Drug Safety and Toxicity Patricia McGrath Zebrafish. Methods for Assessing Drug Safety and Toxicity Новинка

Patricia McGrath Zebrafish. Methods for Assessing Drug Safety and Toxicity

9047.97 руб.
Zebrafish: Methods for Assessing Drug Safety and Toxicity offers a practical guide for using zebrafish as a tool for toxicology studies. Consolidating key protocols and approaches to help researchers navigate the important and evolving field of zebrafish models for toxicity screening, this new title describes the methods for using the zebrafish as a model organism to assess compound-induced toxicity on all major organs. Individual chapters that concentrate on assays for each organ system are included and various analytical tools including microscopy, microplate readers, high content imaging systems, ECG, blood pressure monitors, high speed video and motion detectors are described.
Henrik Holbech Statistical Analysis of Ecotoxicity Studies Henrik Holbech Statistical Analysis of Ecotoxicity Studies Новинка

Henrik Holbech Statistical Analysis of Ecotoxicity Studies

8652.43 руб.
A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book’s topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: • Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals • Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity • Includes an introduction to toxicity experiments and statistical analysis basics • Includes programs in R and excel • Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues • Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.
Emanuela Corsini Molecular Immunotoxicology Emanuela Corsini Molecular Immunotoxicology Новинка

Emanuela Corsini Molecular Immunotoxicology

14036.82 руб.
The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.
Yuliang Zhao Toxicology of Nanomaterials Yuliang Zhao Toxicology of Nanomaterials Новинка

Yuliang Zhao Toxicology of Nanomaterials

13676.92 руб.
This book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.
Granino Korn A. Advanced Dynamic-System Simulation. Model Replication and Monte Carlo Studies Granino Korn A. Advanced Dynamic-System Simulation. Model Replication and Monte Carlo Studies Новинка

Granino Korn A. Advanced Dynamic-System Simulation. Model Replication and Monte Carlo Studies

8751.32 руб.
A unique, hands-on guide to interactive modeling and simulation of engineering systems This book describes advanced, cutting-edge techniques for dynamic system simulation using the DESIRE modeling/simulation software package. It offers detailed guidance on how to implement the software, providing scientists and engineers with powerful tools for creating simulation scenarios and experiments for such dynamic systems as aerospace vehicles, control systems, or biological systems. Along with two new chapters on neural networks, Advanced Dynamic-System Simulation, Second Edition revamps and updates all the material, clarifying explanations and adding many new examples. A bundled CD contains an industrial-strength version of OPEN DESIRE as well as hundreds of program examples that readers can use in their own experiments. The only book on the market to demonstrate model replication and Monte Carlo simulation of real-world engineering systems, this volume: Presents a newly revised systematic procedure for difference-equation modeling Covers runtime vector compilation for fast model replication on a personal computer Discusses parameter-influence studies, introducing very fast vectorized statistics computation Highlights Monte Carlo studies of the effects of noise and manufacturing tolerances for control-system modeling Demonstrates fast, compact vector models of neural networks for control engineering Features vectorized programs for fuzzy-set controllers, partial differential equations, and agro-ecological modeling Advanced Dynamic-System Simulation, Second Edition is a truly useful resource for researchers and design engineers in control and aerospace engineering, ecology, and agricultural planning. It is also an excellent guide for students using DESIRE.
Granino Korn A. Advanced Dynamic-System Simulation. Model Replication and Monte Carlo Studies Granino Korn A. Advanced Dynamic-System Simulation. Model Replication and Monte Carlo Studies Новинка

Granino Korn A. Advanced Dynamic-System Simulation. Model Replication and Monte Carlo Studies

8494.21 руб.
A unique, hands-on guide to interactive modeling and simulation of engineering systems This book describes advanced, cutting-edge techniques for dynamic system simulation using the DESIRE modeling/simulation software package. It offers detailed guidance on how to implement the software, providing scientists and engineers with powerful tools for creating simulation scenarios and experiments for such dynamic systems as aerospace vehicles, control systems, or biological systems. Along with two new chapters on neural networks, Advanced Dynamic-System Simulation, Second Edition revamps and updates all the material, clarifying explanations and adding many new examples. A bundled CD contains an industrial-strength version of OPEN DESIRE as well as hundreds of program examples that readers can use in their own experiments. The only book on the market to demonstrate model replication and Monte Carlo simulation of real-world engineering systems, this volume: Presents a newly revised systematic procedure for difference-equation modeling Covers runtime vector compilation for fast model replication on a personal computer Discusses parameter-influence studies, introducing very fast vectorized statistics computation Highlights Monte Carlo studies of the effects of noise and manufacturing tolerances for control-system modeling Demonstrates fast, compact vector models of neural networks for control engineering Features vectorized programs for fuzzy-set controllers, partial differential equations, and agro-ecological modeling Advanced Dynamic-System Simulation, Second Edition is a truly useful resource for researchers and design engineers in control and aerospace engineering, ecology, and agricultural planning. It is also an excellent guide for students using DESIRE.
John Clary J. The Toxicology of Methanol John Clary J. The Toxicology of Methanol Новинка

John Clary J. The Toxicology of Methanol

10160.43 руб.
The Toxicology of Methanol presents a single source of information and an understanding of the toxicity of methanol from animal data, potential environmental effects as well as human effects. The animal data, which goes to making up the majority of the data on the toxicity of methanol and the mechanism of action, is reviewed as it relates to the potential toxicity in humans.
Allan Hackshaw A Concise Guide to Observational Studies in Healthcare Allan Hackshaw A Concise Guide to Observational Studies in Healthcare Новинка

Allan Hackshaw A Concise Guide to Observational Studies in Healthcare

3594.91 руб.
A Concise Guide to Observational Studies in Healthcare provides busy healthcare professionals with an easy-to-read introduction and overview to conducting, analysing and assessing observational studies. It is a suitable introduction for anyone without prior knowledge of study design, analysis or conduct as the important concepts are presented throughout the text. It provides an overview to the features of design, analyses and conduct of observational studies, without using mathematical formulae, or complex statistics or terminology and is a useful guide for researchers conducting their own studies, those who participate in studies co-ordinated by others, or who read or review a published report of an observational study. Examples are based on clinical features of people, biomarkers, lifestyle habits and environmental exposures, and evaluating quality of care.
Pablo Steinberg High-Throughput Screening Methods in Toxicity Testing Pablo Steinberg High-Throughput Screening Methods in Toxicity Testing Новинка

Pablo Steinberg High-Throughput Screening Methods in Toxicity Testing

12237.01 руб.
Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's «Toxicity Testing in the 21st Century: A Vision and Strategy» and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing. High-Throughput Screening Methods in Toxicity Testing is divided into five parts: General aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profiling Assessing different cytotoxicity endpoints Assessing DNA damage and carcinogenesis Assessing reproductive toxicity, cardiotoxicity, and haematotoxicity Assessing drug metabolism and receptor-related toxicity Each chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined. Throughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods. This book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.
Meghan Manfra McGlinn The Wiley Handbook of Social Studies Research Meghan Manfra McGlinn The Wiley Handbook of Social Studies Research Новинка

Meghan Manfra McGlinn The Wiley Handbook of Social Studies Research

14036.82 руб.
The Wiley Handbook of Social Studies Research is a wide-ranging resource on the current state of social studies education. This timely work not only reflects on the many recent developments in the field, but also explores emerging trends. This is the first major reference work on social studies education and research in a decade An in-depth look at the current state of social studies education and emerging trends Three sections cover: foundations of social studies research, theoretical and methodological frameworks guiding social studies research, and current trends and research related to teaching and learning social studies A state-of-the-art guide for both graduate students and established researchers Guided by an advisory board of well-respected scholars in social studies education research
Mohamed Ibrahim A. Disturbance Analysis for Power Systems Mohamed Ibrahim A. Disturbance Analysis for Power Systems Новинка

Mohamed Ibrahim A. Disturbance Analysis for Power Systems

12678.29 руб.
More than ninety case studies shed new light on power system phenomena and power system disturbances Based on the author's four decades of experience, this book enables readers to implement systems in order to monitor and perform comprehensive analyses of power system disturbances. Most importantly, readers will discover the latest strategies and techniques needed to detect and resolve problems that could lead to blackouts to ensure the smooth operation and reliability of any power system. Logically organized, Disturbance Analysis for Power Systems begins with an introduction to the power system disturbance analysis function and its implementation. The book then guides readers through the causes and modes of clearing of phase and ground faults occurring within power systems as well as power system phenomena and their impact on relay system performance. The next series of chapters presents more than ninety actual case studies that demonstrate how protection systems have performed in detecting and isolating power system disturbances in: Generators Transformers Overhead transmission lines Cable transmission line feeders Circuit breaker failures Throughout these case studies, actual digital fault recording (DFR) records, oscillograms, and numerical relay fault records are presented and analyzed to demonstrate why power system disturbances happen and how the sequence of events are deduced. The final chapter of the book is dedicated to practice problems, encouraging readers to apply what they've learned to perform their own system disturbance analyses. This book makes it possible for engineers, technicians, and power system operators to perform expert power system disturbance analyses using the latest tested and proven methods. Moreover, the book's many cases studies and practice problems make it ideal for students studying power systems.
Michelle Connolly J. The Cardiovascular System at a Glance Michelle Connolly J. The Cardiovascular System at a Glance Новинка

Michelle Connolly J. The Cardiovascular System at a Glance

3163.3 руб.
This concise and accessible text provides an integrated overview of the cardiovascular system – considering the basic sciences which underpin the system and applying this knowledge to clinical practice and therapeutics. A general introduction to the cardiovascular system is followed by chapters on key topics such as anatomy and histology, blood and body fluids, biochemistry, excitation-contraction coupling, form and function, integration and regulation, pathology and therapeutics, clinical examination and investigation – all supported by clinical cases for self-assessment. Highly visual colour illustrations complement the text and consolidate learning. The Cardiovascular System at a Glance is the perfect introduction and revision aid to understanding the heart and circulation and now also features: An additional chapter on pulmonary hypertension Even more simplified illustrations to aid easier understanding Reorganized and revised chapters for greater clarity Brand new and updated clinical case studies illustrating clinical relevance and for self-assessment The fourth edition of The Cardiovascular System at a Glance is an ideal resource for medical students, whilst students of other health professions and specialist cardiology nurses will also find it invaluable. Examination candidates who need an authoritative, concise, and clinically relevant guide to the cardiovascular system will find it extremely useful. A companion website featuring cases from this and previous editions, along with additional summary revision aids, is available at www.ataglanceseries.com/cardiovascular.
Mohamed Abou-Donia Mammalian Toxicology Mohamed Abou-Donia Mammalian Toxicology Новинка

Mohamed Abou-Donia Mammalian Toxicology

9718.01 руб.
Mammalian Toxicology surveys chemical agents and examines how such chemicals impact on human health, emphasizing the importance in minimizing environmental exposure to chemical and physical hazards in our homes, communities and workplaces through such media as contaminated water, soil and air. Starting with the basic principles on a wide range of toxic agents, this textbook describes how they enter the body, their mechanisms of action once inside, and strategies for diagnosis, prevention and treatment. Topics covered include: General principles of toxicology: pharmacological and toxicological principles underpinning the study of toxicology, risk assessments and mechanisms of cell death Disposition: routes of chemical exposures, entry into the body and various tissues, storage, metabolic biotransformation and elimination, with examples from various toxicants. Toxic agents: the occurrences, disposition in the body, health effects, toxic mechanisms, antidotes and treatments of a range of agents including pesticides, metals, solvents, gases, nanomaterials, food components and additives, pharmaceuticals, drugs of abuse, natural toxins, endocrine disruptors, radiation, and warfare weapons. Toxic effects: including neurotoxicity, developmental toxicity, immunotoxicity, teratogenecity, male and female reproductive toxicity, mutagenecity, carcinogenicity, pulmonary toxicity, cardiovascular toxicity, hepatotoxicity, gastrointestinal toxicity and cardiovascular toxicity Toxicology and society: epidemiological studies of chemical-induced diseases in human populations, and a vision for toxicology in the 21st century. Mammalian Toxicology is an essential primer for students of toxicology, biochemistry, biology, medicine and chemistry. It is also appropriate for professional toxicologists in research or regulatory affairs, and anyone who needs to understand the adverse effects of toxic agents on the human body.
Sandra Bermann A Companion to Translation Studies Sandra Bermann A Companion to Translation Studies Новинка

Sandra Bermann A Companion to Translation Studies

14824.91 руб.
This companion offers a wide-ranging introduction to the rapidly expanding field of translation studies, bringing together some of the best recent scholarship to present its most important current themes Features new work from well-known scholars Includes a broad range of geo-linguistic and theoretical perspectives Offers an up-to-date overview of an expanding field A thorough introduction to translation studies for both undergraduates and graduates Multi-disciplinary relevance for students with diverse career goals
Zaher Radi A. Comparative Pathophysiology and Toxicology of Cyclooxygenases Zaher Radi A. Comparative Pathophysiology and Toxicology of Cyclooxygenases Новинка

Zaher Radi A. Comparative Pathophysiology and Toxicology of Cyclooxygenases

11124.56 руб.
The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases (COXs) are enzymes responsible for the formation of an important class of biological mediators called prostanoids. Prostanoids such as prostaglandins mediate inflammatory and anaphylactic reactions. For those suffering from inflammation and pain, the pharmacological inhibition of COXs, with non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, can provide relief. Yet the use of NSAIDs can trigger toxicological effects as well, leading to potential health risks. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited. The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as an historical perspective. Shedding light on the differences in expression, pathophysiology, and toxicology of COX inhibitors across species, the book offers a systematic examination of the effects and pathophysiology of COX inhibitors and their mechanisms of toxicity, beginning with the GI tract. Subsequent chapters cover: The pathophysiology of COX inhibition on bone, tendon, and ligament healing COX inhibitors and renal system pathophysiology and mechanisms of toxicity The pathophysiologic role of COX inhibition in the ocular system COX inhibition and the respiratory and cardiovascular systems The book also sheds light on the latest research devoted to developing COX inhibitors with no adverse side-effects. The first book to offer a thorough comparative look at the toxicological effects of COX inhibitors throughout the body, this invaluable resource will help advance the research and development of safer and more effective COX drugs.
Daniel Shain H. Annelids in Modern Biology Daniel Shain H. Annelids in Modern Biology Новинка

Daniel Shain H. Annelids in Modern Biology

13049.11 руб.
Annelids offer a diversity of experimentally accessible features making them a rich experimental subject across the biological sciences, including evolutionary development, neurosciences and stem cell research. This volume introduces the Annelids and their utility in evolutionary developmental biology, neurobiology, and environmental/ecological studies, including extreme environments. The book demonstrates the variety of fields in which Annelids are already proving to be a useful experimental system. Describing the utility of Annelids as a research model, this book is an invaluable resource for all researchers in the field.
John Rowe Carlos A Concise Companion to American Studies John Rowe Carlos A Concise Companion to American Studies Новинка

John Rowe Carlos A Concise Companion to American Studies

14829.04 руб.
A Companion to American Studies is an essential volume that brings together voices and scholarship from across the spectrum of American experience. A collection of 22 original essays which provides an unprecedented introduction to the «new» American Studies: a comparative, transnational, postcolonial and polylingual discipline Addresses a variety of subjects, from foundations and backgrounds to the field, to different theories of the “new” American Studies, and issues from globalization and technology to transnationalism and post-colonialism Explores the relationship between American Studies and allied fields such as Ethnic Studies, Feminist, Queer and Latin American Studies Designed to provoke discussion and help students and scholars at all levels develop their own approaches to contemporary American Studies
Louis Komjathy Introducing Contemplative Studies Louis Komjathy Introducing Contemplative Studies Новинка

Louis Komjathy Introducing Contemplative Studies

6834.7 руб.
The first book-length introduction to an exciting new interdisciplinary field—written by an internationally recognized leader of the Contemplative Studies movement This is the first book-length introduction to a growing and influential interdisciplinary field focused on contemplative practice, contemplative experience, and contemplative pedagogy. Written by an internationally recognized leader in the area, Introducing Contemplative Studies seeks to provide readers with a deep and practical understanding of the nature and purpose of the field while encouraging them to find a place of their own in an increasingly widespread movement. At once comprehensive overview, critical reflection, and visionary proposal, the book explores the central approaches and issues in Contemplative Studies, tackles questions and problems that sometimes go unaddressed, and identifies promising new developments. The author also discusses contemplative pedagogy, an experiential approach to teaching and learning informed by and expressed as contemplative practice. This is a major introduction to a fast emerging interdisciplinary field that will be invaluable to those interested in the area. The only comprehensive introduction to the emerging, interdisciplinary field of Contemplative Studies Written by a distinguished leader in the Contemplative Studies movement who is founding Co-Chair of the Contemplative Studies Group of the American Academy of Religion Informed by ten years of research and practice, the book explores the field’s varied approaches and expressions Offers critical reviews of trends which will create discussions both within and outside the Contemplative Studies Liberally illustrated with both images and charts Introducing Contemplative Studies is a must-read for advanced undergraduates, graduate students, teachers and scholars in Contemplative Studies, as well as anyone who is curious about contemplative practice, meditation, contemplative experience, contemplative pedagogy, contemplative science, and, of course, the exciting field of Contemplative Studies generally.
Dean Karnopp C. System Dynamics. Modeling, Simulation, and Control of Mechatronic Systems Dean Karnopp C. System Dynamics. Modeling, Simulation, and Control of Mechatronic Systems Новинка

Dean Karnopp C. System Dynamics. Modeling, Simulation, and Control of Mechatronic Systems

11517.51 руб.
An expanded new edition of the bestselling system dynamics book using the bond graph approach A major revision of the go-to resource for engineers facing the increasingly complex job of dynamic systems design, System Dynamics, Fifth Edition adds a completely new section on the control of mechatronic systems, while revising and clarifying material on modeling and computer simulation for a wide variety of physical systems. This new edition continues to offer comprehensive, up-to-date coverage of bond graphs, using these important design tools to help readers better understand the various components of dynamic systems. Covering all topics from the ground up, the book provides step-by-step guidance on how to leverage the power of bond graphs to model the flow of information and energy in all types of engineering systems. It begins with simple bond graph models of mechanical, electrical, and hydraulic systems, then goes on to explain in detail how to model more complex systems using computer simulations. Readers will find: New material and practical advice on the design of control systems using mathematical models New chapters on methods that go beyond predicting system behavior, including automatic control, observers, parameter studies for system design, and concept testing Coverage of electromechanical transducers and mechanical systems in plane motion Formulas for computing hydraulic compliances and modeling acoustic systems A discussion of state-of-the-art simulation tools such as MATLAB and bond graph software Complete with numerous figures and examples, System Dynamics, Fifth Edition is a must-have resource for anyone designing systems and components in the automotive, aerospace, and defense industries. It is also an excellent hands-on guide on the latest bond graph methods for readers unfamiliar with physical system modeling.
CCPS (Center for Chemical Process Safety) Guidelines for Implementing Process Safety Management CCPS (Center for Chemical Process Safety) Guidelines for Implementing Process Safety Management Новинка

CCPS (Center for Chemical Process Safety) Guidelines for Implementing Process Safety Management

9270.47 руб.
The 2nd edition provides an update of information since the publication of the first edition including best practices for managing process safety developed by industry as well as incorporate the additional process safety elements. In addition the book includes a focus on maintaining and improving a Process Safety Management (PSM) System. This 2nd edition also provides «how to information to» determine process safety performance status, implement one or more new elements into an existing PSM system, maintain or improve an existing PSM system, and manage future process safety performance.
Gilbert Rodman B. Why Cultural Studies? Gilbert Rodman B. Why Cultural Studies? Новинка

Gilbert Rodman B. Why Cultural Studies?

6151.88 руб.
Why Cultural Studies? is a rallying call for a reinvigoration of the project of cultural studies that provides a critical analysis of its meteoric rise to the academic fore and makes a convincing argument for the pressing need for a renewed investment in, and re-evaluation of, its core ideals. Rodman argues that there are valuable lessons we can learn from cultural studies’ past that have the potential to lead cultural studies to an invigorated and viable future Makes the claim that cultural studies isn’t – and shouldn’t be – solely an academic subject, but open to both academics and non-academics alike Asserts that now more than ever cultural studies has a productive role to play in promoting social justice and building a better world Written by one of the leading figures in the area of cultural studies, and the current Chair of the Association for Cultural Studies
Grigorios Kalivas Digital Radio System Design Grigorios Kalivas Digital Radio System Design Новинка

Grigorios Kalivas Digital Radio System Design

9122.14 руб.
A systematic explanation of the principles of radio systems, Digital Radio System Design offers a balanced treatment of both digital transceiver modems and RF front-end subsystems and circuits. It provides an in-depth examination of the complete transceiver chain which helps to connect the two topics in a unified system concept. Although the book tackles such diverse fields it treats them in sufficient depth to give the designer a solid foundation and an implementation perspective. Covering the key concepts and factors that characterise and impact radio transmission and reception, the book presents topics such as receiver design, noise and distortion. Information is provided about more advanced aspects of system design such as implementation losses due to non-idealities. Providing vivid examples, illustrations and detailed case-studies, this book is an ideal introduction to digital radio systems design. Offers a balanced treatment of digital modem and RF front-end design concepts for complete transceivers Presents a diverse range of topics related to digital radio design including advanced transmission and synchronization techniques with emphasis on implementation Provides guidance on imperfections and non-idealities in radio system design Includes detailed design case-studies incorporating measurement and simulation results to illustrate the theory in practice
Li Han-Xiong System Design and Control Integration for Advanced Manufacturing Li Han-Xiong System Design and Control Integration for Advanced Manufacturing Новинка

Li Han-Xiong System Design and Control Integration for Advanced Manufacturing

6893.52 руб.
Most existing robust design books address design for static systems, or achieve robust design from experimental data via the Taguchi method. Little work considers model information for robust design particularly for the dynamic system. This book covers robust design for both static and dynamic systems using the nominal model information or the hybrid model/data information, and also integrates design with control under a large operating region. This design can handle strong nonlinearity and more uncertainties from model and parameters.
Zhengyou He Wavelet Analysis and Transient Signal Processing Applications for Power Systems Zhengyou He Wavelet Analysis and Transient Signal Processing Applications for Power Systems Новинка

Zhengyou He Wavelet Analysis and Transient Signal Processing Applications for Power Systems

9358.11 руб.
An original reference applying wavelet analysis to power systems engineering • Introduces a modern signal processing method called wavelet analysis, and more importantly, its applications to power system fault detection and protection • Concentrates on its application to the power system, offering great potential for fault detection and protection • Presents applications, examples, and case studies, together with the latest research findings • Provides a combination of the author’s tutorial notes from electrical engineering courses together with his own original research work, of interest to both industry and academia
Patrice Micouin Model Based Systems Engineering. Fundamentals and Methods Patrice Micouin Model Based Systems Engineering. Fundamentals and Methods Новинка

Patrice Micouin Model Based Systems Engineering. Fundamentals and Methods

9645.62 руб.
This book is a contribution to the definition of a model based system engineering (MBSE) approach, designed to meet the objectives laid out by the INCOSE. After pointing out the complexity that jeopardizes a lot of system developments, the book examines fundamental aspects of systems under consideration. It goes on to address methodological issues and proposes a methodic approach of MBSE that provides, unlike current practices, systematic and integrated model-based engineering processes. An annex describes relevant features of the VHDL-AMS language supporting the methodological issues described in the book.
Aran MacKinnon An Introduction to Global Studies Aran MacKinnon An Introduction to Global Studies Новинка

Aran MacKinnon An Introduction to Global Studies

8637.62 руб.
Taking an interdisciplinary approach, An Introduction to Global Studies presents readers with a solid introduction to the complex, interconnected forces and issues confronting today's globalized world. Introduces readers to major theories, key terms, concepts, and notable theorists Equips readers with the basic knowledge and conceptual tools necessary for thinking critically about the complex issues facing the global community Includes a variety of supplemental features to facilitate learning and enhance readers' understanding of the material
Wilson Thomas M. A Companion to Border Studies Wilson Thomas M. A Companion to Border Studies Новинка

Wilson Thomas M. A Companion to Border Studies

15867.33 руб.
A Companion to Border Studies introduces an exciting and expanding field of interdisciplinary research, through the writing of an international array of scholars, from diverse perspectives that include anthropology, development studies, geography, history, political science and sociology. Explores how nations and cultural identities are being transformed by their dynamic, shifting borders where mobility is sometimes facilitated, other times impeded or prevented Offers an array of international views which together form an authoritative guide for students, instructors and researchers Reflects recent significant growth in the importance of understanding the distinctive characteristics of borders and frontiers, including cross-border cooperation, security and controls, migration and population displacements, hybridity, and transnationalism
Robert Schunk W. Modeling the Ionosphere-Thermosphere, Volume 201 Robert Schunk W. Modeling the Ionosphere-Thermosphere, Volume 201 Новинка

Robert Schunk W. Modeling the Ionosphere-Thermosphere, Volume 201

9645.62 руб.
Published by the American Geophysical Union as part of the Geophysical Monograph Series, Volume 201. Modeling the Ionosphere-Thermosphere System brings together for the first time a detailed description of the physics of the IT system in conjunction with numerical techniques to solve the complex system of equations that describe the system, as well as issues of current interest. Volume highlights include discussions of: Physics of the ionosphere and thermosphere IT system, and the numerical methods to solve the basic equations of the IT system The physics and numerical methods to determine the global electrodynamics of the IT system The response of the IT system to forcings from below (i.e., the lower atmosphere) and from above (i.e., the magnetosphere) The physics and numerical methods to model ionospheric irregularities Data assimilation techniques, comparison of model results to data, climate variability studies, and applications to space weather Providing a clear description of the physics of this system in several tutorial-like articles, Modeling the Ionosphere-Thermosphere System is of value to the upper atmosphere science community in general. Chapters describing details of the numerical methods used to solve the equations that describe the IT system make the volume useful to both active researchers in the field and students.
Charles Wasson S. System Engineering Analysis, Design, and Development. Concepts, Principles, and Practices Charles Wasson S. System Engineering Analysis, Design, and Development. Concepts, Principles, and Practices Новинка

Charles Wasson S. System Engineering Analysis, Design, and Development. Concepts, Principles, and Practices

9718.01 руб.
Praise for the first edition: “This excellent text will be useful to every system engineer (SE) regardless of the domain. It covers ALL relevant SE material and does so in a very clear, methodical fashion. The breadth and depth of the author's presentation of SE principles and practices is outstanding.” –Philip Allen This textbook presents a comprehensive, step-by-step guide to System Engineering analysis, design, and development via an integrated set of concepts, principles, practices, and methodologies. The methods presented in this text apply to any type of human system – small, medium, and large organizational systems and system development projects delivering engineered systems or services across multiple business sectors such as medical, transportation, financial, educational, governmental, aerospace and defense, utilities, political, and charity, among others. Provides a common focal point for “bridging the gap” between and unifying System Users, System Acquirers, multi-discipline System Engineering, and Project, Functional, and Executive Management education, knowledge, and decision-making for developing systems, products, or services Each chapter provides definitions of key terms, guiding principles, examples, author’s notes, real-world examples, and exercises, which highlight and reinforce key SE&D concepts and practices Addresses concepts employed in Model-Based Systems Engineering (MBSE), Model-Driven Design (MDD), Unified Modeling Language (UMLTM) / Systems Modeling Language (SysMLTM), and Agile/Spiral/V-Model Development such as user needs, stories, and use cases analysis; specification development; system architecture development; User-Centric System Design (UCSD); interface definition & control; system integration & test; and Verification & Validation (V&V) Highlights/introduces a new 21st Century Systems Engineering & Development (SE&D) paradigm that is easy to understand and implement. Provides practices that are critical staging points for technical decision making such as Technical Strategy Development; Life Cycle requirements; Phases, Modes, & States; SE Process; Requirements Derivation; System Architecture Development, User-Centric System Design (UCSD); Engineering Standards, Coordinate Systems, and Conventions; et al. Thoroughly illustrated, with end-of-chapter exercises and numerous case studies and examples, Systems Engineering Analysis, Design, and Development, Second Edition is a primary textbook for multi-discipline, engineering, system analysis, and project management undergraduate/graduate level students and a valuable reference for professionals.
Paul Brandon R. Research on Evaluation. New Directions for Evaluation, Number 148 Paul Brandon R. Research on Evaluation. New Directions for Evaluation, Number 148 Новинка

Paul Brandon R. Research on Evaluation. New Directions for Evaluation, Number 148

2087.02 руб.
This issue broaden the field’s understanding of Research on Evaluation (RoE) in practice, with a focus on empirical RoE. Considering the full collection of RoE studies, it defines RoE as systematic empirical inquiry resulting in original findings or in reexaminations of existing data about the practice, methods, or profession of program evaluation. RoE inquiries address: the inputs into evaluations, the contexts within which evaluations are conducted, the full range of methods and activities of evaluations, evaluation’s proximal or distal effects, or the professional issues that evaluators encounter. The inquiries include case studies, reflective narratives, studies about evaluation methods, literature reviews, oral histories, bibliometric studies, meta-evaluations, experiments, longitudinal studies, simulations, and time-series studies. This is the 148th issue in the New Directions for Evaluation series from Jossey-Bass. It is an official publication of the American Evaluation Association.
John Lachin M. Biostatistical Methods. The Assessment of Relative Risks John Lachin M. Biostatistical Methods. The Assessment of Relative Risks Новинка

John Lachin M. Biostatistical Methods. The Assessment of Relative Risks

11940.36 руб.
Praise for the First Edition «. . . an excellent textbook . . . an indispensable reference for biostatisticians and epidemiologists.» —International Statistical Institute A new edition of the definitive guide to classical and modern methods of biostatistics Biostatistics consists of various quantitative techniques that are essential to the description and evaluation of relationships among biologic and medical phenomena. Biostatistical Methods: The Assessment of Relative Risks, Second Edition develops basic concepts and derives an expanded array of biostatistical methods through the application of both classical statistical tools and more modern likelihood-based theories. With its fluid and balanced presentation, the book guides readers through the important statistical methods for the assessment of absolute and relative risks in epidemiologic studies and clinical trials with categorical, count, and event-time data. Presenting a broad scope of coverage and the latest research on the topic, the author begins with categorical data analysis methods for cross-sectional, prospective, and retrospective studies of binary, polychotomous, and ordinal data. Subsequent chapters present modern model-based approaches that include unconditional and conditional logistic regression; Poisson and negative binomial models for count data; and the analysis of event-time data including the Cox proportional hazards model and its generalizations. The book now includes an introduction to mixed models with fixed and random effects as well as expanded methods for evaluation of sample size and power. Additional new topics featured in this Second Edition include: Establishing equivalence and non-inferiority Methods for the analysis of polychotomous and ordinal data, including matched data and the Kappa agreement index Multinomial logistic for polychotomous data and proportional odds models for ordinal data Negative binomial models for count data as an alternative to the Poisson model GEE models for the analysis of longitudinal repeated measures and multivariate observations Throughout the book, SAS is utilized to illustrate applications to numerous real-world examples and case studies. A related website features all the data used in examples and problem sets along with the author's SAS routines. Biostatistical Methods, Second Edition is an excellent book for biostatistics courses at the graduate level. It is also an invaluable reference for biostatisticians, applied statisticians, and epidemiologists.
Bernard Mineo A Companion to Livy Bernard Mineo A Companion to Livy Новинка

Bernard Mineo A Companion to Livy

14464.33 руб.
A Companion to Livy features a collection of essays representing the most up-to-date international scholarship on the life and works of the Roman historian Livy. Features contributions from top Livian scholars from around the world Presents for the first time a new interpretation of Livy's historical philosophy, which represents a key to an overall interpretation of Livy's body of work Includes studies of Livy's work from an Indo-European comparative aspect Provides the most modern studies on literary archetypes for Livy's narrative of the history of early Rome
Dennis Smith A. Metabolite Safety in Drug Development Dennis Smith A. Metabolite Safety in Drug Development Новинка

Dennis Smith A. Metabolite Safety in Drug Development

14036.82 руб.
A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA. • Reviews the analytical techniques and experimental designs critical for metabolite studies • Covers methods including chirality, species differences, mass spectrometry, radiolabels, and in vitro / in vivo correlation • Discusses target pharmacology, in vitro systems aligned to toxicity tests, and drug-drug interactions • Includes perspectives from authors with firsthand involvement in industry and the study of drug metabolites, including viewpoints that have influenced regulatory guidelines
Bulstrode Christopher Rheumatology, Orthopaedics and Trauma at a Glance Bulstrode Christopher Rheumatology, Orthopaedics and Trauma at a Glance Новинка

Bulstrode Christopher Rheumatology, Orthopaedics and Trauma at a Glance

3556.15 руб.
Rheumatology, Orthopaedics and Trauma at a Glance is the new edition of The Musculoskeletal System at a Glance. The book now includes not just basic anatomy, but also features presenting complaints and patient examination and reflects the increased coverage of rheumatology, making it relevant for students at all levels. Rheumatology, Orthopaedics and Trauma at a Glance Expands its coverage of rheumatology to include all major topics on the medical student curriculum Includes fully illustrated chapters on examination of each part of the musculoskeletal system Provides self-assessment case studies to test knowledge and provide clinical context Consolidates all information relating to the musculoskeletal system in one title Rheumatology, Orthopaedics and Trauma at a Glance is ideal for all medical students studying the musculoskeletal system or taking an orthopaedics or rheumatology rotation.
Oriol Gomis-Bellmunt HVDC Grids. For Offshore and Supergrid of the Future Oriol Gomis-Bellmunt HVDC Grids. For Offshore and Supergrid of the Future Новинка

Oriol Gomis-Bellmunt HVDC Grids. For Offshore and Supergrid of the Future

10077.23 руб.
This book discusses HVDC grids based on multi-terminal voltage-source converters (VSC), which is suitable for the connection of offshore wind farms and a possible solution for a continent wide overlay grid. HVDC Grids: For Offshore and Supergrid of the Future begins by introducing and analyzing the motivations and energy policy drives for developing offshore grids and the European Supergrid. HVDC transmission technology and offshore equipment are described in the second part of the book. The third part of the book discusses how HVDC grids can be developed and integrated in the existing power system. The fourth part of the book focuses on HVDC grid integration, in studies, for different time domains of electric power systems. The book concludes by discussing developments of advanced control methods and control devices for enabling DC grids. Presents the technology of the future offshore and HVDC grid Explains how offshore and HVDC grids can be integrated in the existing power system Provides the required models to analyse the different time domains of power system studies: from steady-state to electromagnetic transients This book is intended for power system engineers and academics with an interest in HVDC or power systems, and policy makers. The book also provides a solid background for researchers working with VSC-HVDC technologies, power electronic devices, offshore wind farm integration, and DC grid protection.
Ming-Li Shiu Quality Strategy for Research and Development Ming-Li Shiu Quality Strategy for Research and Development Новинка

Ming-Li Shiu Quality Strategy for Research and Development

8494.21 руб.
Provides a clear, useful framework and methods for R&D, including robust technology development, product planning, and product design and development management Quality Strategy for Research and Development integrates the Japanese and Western perspectives on Quality Function Deployment (QFD), updates the strategy of Robust Engineering (RE), and relates their unique frameworks to current, widely adopted philosophies of quality assurance. Featuring real-world case studies, more than thirty tables, and over seventy figures, this essential guide identifies key issues and proposes improvements in the current R&D paradigm. It offers in-depth coverage of technology development, product planning, and product design and development management. Quality Strategy for Research and Development: Updates the conventional approaches to QFD and RE, and provides the implementation model of combining them into a corporate operating system Identifies key issues in the current practice of R&D, and provides solutions for improving design quality and R&D productivity Includes the case studies of designing a functional circuit, magnetic component, measurement system, and machining equipment Offers the integration models of QFD and other breakthrough strategies including DFX (Design For eXcellence), DFSS (Design For Six Sigma), and Blue Ocean Strategy Written for R&D executives, managers, engineers, and quality practitioners, Quality Strategy for Research and Development is also an ideal text for professors and students of industrial and systems engineering, technology management, and business administration.
R. Sabnis W. Handbook of Fluorescent Dyes and Probes R. Sabnis W. Handbook of Fluorescent Dyes and Probes Новинка

R. Sabnis W. Handbook of Fluorescent Dyes and Probes

12596.53 руб.
A COMPLETE, UP-TO-DATE RESOURCE OF INFORMATION ON MORE THAN 150 FLUORESCENT DYES AND PROBES Handbook of Fluorescent Dyes and Probes is the most comprehensive volume available on the subject, covering all the available dyes and probes known to date in the literature for uses in various fields. Top dye expert Dr. Ram Sabnis organizes the compounds alphabetically by the most commonly used chemical name. He presents an easy-to-use reference complete with novel ideas for breakthrough research in medical, biological, chemical, color, material, physical and related allied fields. The ease of use of the handbook is further enhanced by various appendixes provided at the end of the book to conveniently and easily locate the dye as per the reader's need. This is the first book to give the CAS registry numbers, chemical structure, Chemical Abstract (CA) index name, all other chemical names, Merck Index number, chemical/dye class, molecular formula, molecular weight, physical form, solubility, melting point, boiling point, pKa, absorption maxima, emission maxima, molar extinction coefficient, and quantum yield of fluorescent dyes and probes, as well as to provide access to synthetic procedures (lab scale and industrial scale) of dyes and probes in a single source. This user-friendly handbook also features references on safety, toxicity and adverse effects of dyes and probes on humans, animals and the environment, including: acute/chronic toxicity aquatic toxicity carcinogenicity cytotoxicity ecotoxicity genotoxocity hematotoxicity hepatotoxicity immunotoxicity marine toxicity microbial toxicity mutagenicity nephrotoxicity neurotoxicity nucleic acid damage oral toxicity phototoxicity phytotoxicity reproductive toxicity skin toxicity Containing imaging/labeling applications, biological/medical applications and industrial applications, Handbook of Fluorescent Dyes and Probes is a convenient, vital resource for industrial and academic researchers, and a valuable desktop reference for medical professionals, lab supervisors, scientists, chemists, biologists, engineers, physicists, intellectual property professionals, students, and professors. Includes all fluorescent dyes & probes known to date and provides a complete, up-to-date library of information in one reference/handbook Includes more than 300 fluorescent dyes & probes organized alphabetically by the commonly used Chemical Name Provides access to synthesis procedures (lab scale and industrial scale) of fluorescent dyes & probes First book to provide references on safety, toxicity and adverse effects of fluorescent dyes and probes on humans, animals, and the environment User-friendly and convenient resource guide for chemical, biological, medical, and intellectual property professionals in a broad range of disciplines
Hugo Kubinyi Reactive Drug Metabolites Hugo Kubinyi Reactive Drug Metabolites Новинка

Hugo Kubinyi Reactive Drug Metabolites

14036.82 руб.
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the structure-toxicity relationships for drugs. Two chapters are dedicated to the currently hot topics of herbal constituents and IADRs. The next part covers current strategies and approaches to evaluate the reactive metabolite potential of new drug candidates, both by predictive and by bioanalytical methods. There then follows an in-depth analysis of the toxicological potential of the top 200 prescription drugs, illustrating the power and the limits of the toxicophore concept, backed by numerous case studies. Finally, a risk-benefi t approach to managing the toxicity risk of reactive metabolite-prone drugs is presented. Since the authors carefully develop the knowledge needed, from fundamental considerations to current industry standards, no degree in pharmacology is required to read this book, making it perfect for medicinal chemists without in-depth pharmacology training.
Javid Farideh Clinical Physiology and Pharmacology. The Essentials Javid Farideh Clinical Physiology and Pharmacology. The Essentials Новинка

Javid Farideh Clinical Physiology and Pharmacology. The Essentials

14680.71 руб.
This book is an accessible collection of case study scenarios ideal for physiology and pharmacology revision for pharmacy, medical, biomedical science, clinical science and healthcare students. Clearly structured and organized by major organ system, the book emphasises ways in which key signs and symptoms of disease inform diagnosis and the choice of treatment, together with the relevant pharmacological mechanisms. Each chapter has a clinical focus and includes clear learning outcomes, key points and model answers with detailed explanations designed to enhance students’ understanding of the physiology and pharmacology underpinning each case study scenario. 50 topics are covered and the cases presented include an extensive range of psychological, neurological, endocrine, cardiovascular, respiratory, renal, gastrointestinal and reproductive disorders, their symptoms, complications and usual treatment along with the actions and uses of some widely- used drugs. An essential revision text designed to help students apply their theoretical knowledge to real-life cases Realistic case studies focusing on commonly occurring conditions and diseases Model answers throughout Learning outcomes provided at the beginning of each chapter Key learning points presented in the cases follow each model answer Helps students to understand the relevance and clinical implications of the topics studied in physiology and pharmacology courses Reinforces major concepts and definitions Includes a glossary with a full list of drugs and disorders to support the text
Alain Cardon Beyond Artificial Intelligence. From Human Consciousness to Artificial Consciousness Alain Cardon Beyond Artificial Intelligence. From Human Consciousness to Artificial Consciousness Новинка

Alain Cardon Beyond Artificial Intelligence. From Human Consciousness to Artificial Consciousness

8343.42 руб.
This book will present a complete modeling of the human psychic system that allows to generate the thoughts in a strictly organizational approach that mixes a rising and falling approach. The model will present the architecture of the psychic system that can generate sensations and thoughts, showing how one can feel thoughts. The model developed into an organizational architecture based on massive multiagent systems. The architecture will be fully developed, showing how an artificial system can be endowed with consciousness and intentionally generate thoughts and, especially, feel them. These results are multidisciplinary, combining both psychology and computer science disciplines.
Gupta Ramesh C. Anticholinesterase Pesticides. Metabolism, Neurotoxicity, and Epidemiology Gupta Ramesh C. Anticholinesterase Pesticides. Metabolism, Neurotoxicity, and Epidemiology Новинка

Gupta Ramesh C. Anticholinesterase Pesticides. Metabolism, Neurotoxicity, and Epidemiology

13497.8 руб.
This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology. The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.
Dennis Buede M. The Engineering Design of Systems. Models and Methods Dennis Buede M. The Engineering Design of Systems. Models and Methods Новинка

Dennis Buede M. The Engineering Design of Systems. Models and Methods

9718.01 руб.
New for the third edition, chapters on: Complete Exercise of the SE Process, System Science and Analytics and The Value of Systems Engineering The book takes a model-based approach to key systems engineering design activities and introduces methods and models used in the real world. This book is divided into three major parts: (1) Introduction, Overview and Basic Knowledge, (2) Design and Integration Topics, (3) Supplemental Topics. The first part provides an introduction to the issues associated with the engineering of a system. The second part covers the critical material required to understand the major elements needed in the engineering design of any system: requirements, architectures (functional, physical, and allocated), interfaces, and qualification. The final part reviews methods for data, process, and behavior modeling, decision analysis, system science and analytics, and the value of systems engineering. Chapter 1 has been rewritten to integrate the new chapters and updates were made throughout the original chapters. Provides an overview of modeling, modeling methods associated with SysML, and IDEF0 Includes a new Chapter 12 that provides a comprehensive review of the topics discussed in Chapters 6 through 11 via a simple system – an automated soda machine Features a new Chapter 15 that reviews General System Theory, systems science, natural systems, cybernetics, systems thinking, quantitative characterization of systems, system dynamics, constraint theory, and Fermi problems and guesstimation Includes a new Chapter 16 on the value of systems engineering with five primary value propositions: systems as a goal-seeking system, systems engineering as a communications interface, systems engineering to avert showstoppers, systems engineering to find and fix errors, and systems engineering as risk mitigation The Engineering Design of Systems: Models and Methods, Third Edition is designed to be an introductory reference for professionals as well as a textbook for senior undergraduate and graduate students in systems engineering.
Margaret Campbell L. Case Studies in Palliative and End-of-Life Care Margaret Campbell L. Case Studies in Palliative and End-of-Life Care Новинка

Margaret Campbell L. Case Studies in Palliative and End-of-Life Care

4894.19 руб.
Case Studies in Palliative and End-of-Life Care uses a case-based approach to provide students and practitioners with an important learning tool to improve critical thinking skills and encourage discussion toward improving experiences for patients and their families. The book is organized into three sections covering subjects related to communication, symptom management, and family care. Each case is presented in a consistent, logical format for ease of use, highlighting key evidence-based concepts including the case history, care setting, diagnosis and prognosis, assessment, treatment considerations, and family support. A key reference, Case Studies in Palliative and End-of-Life Care is an invaluable resource for clinicians who provide palliative care to patients with life-limiting illnesses and those at the end of life along with their families.
Harold Kerzner, Ph.D. Project Management Case Studies Harold Kerzner, Ph.D. Project Management Case Studies Новинка

Harold Kerzner, Ph.D. Project Management Case Studies

4678.71 руб.
THE #1 PROJECT MANAGEMENT CASE STUDIES BOOK NOW FEATURING NEW CASES FROM DISNEY, THE OLYMPICS, AIRBUS, BOEING, AND MORE After on-the-job experience, case studies are the most important part of every project manager's training. This Fifth Edition of Project Management Case Studies features more than one hundred case studies that detail projects at high-profile companies around the world. These cases offer you a unique opportunity to experience, first-hand, project management in action within a variety of contexts and up against some of the most challenging conditions any project manager will likely face. New to this edition are case studies focusing on agile and scrum methodologies. Contains 100-plus case studies from companies that illustrate both successful and not-so-successful project management Represents an array of industries, including medical and pharmaceutical, aerospace, entertainment, sports, manufacturing, finance, telecommunications, and more Features 18 new case studies, including high-profile cases from Disney, the Olympics, Boeing 787 Dreamliner, and Airbus 380 Follows and supports preparation for the Project Management Professional (PMP)® Certification Exam Experienced PMs, project managers in training, and students alike will find this book to be an indispensable resource whether used as a standalone or combined with the bestselling Project Management: A Systems Approach to Planning, Scheduling, and Controlling, 12th Edition. PMI, CAPM, PMBOK, PMP and Project Management Professional are registered marks of the Project Management Institute, Inc.
Hassan Bevrani Power System Monitoring and Control Hassan Bevrani Power System Monitoring and Control Новинка

Hassan Bevrani Power System Monitoring and Control

8565.23 руб.
Power System Monitoring and Control (PSMC) is becoming increasingly significant in the design, planning, and operation of modern electric power systems. In response to the existing challenge of integrating advanced metering, computation, communication, and control into appropriate levels of PSMC, Power System Monitoring and Control presents a comprehensive overview of the basic principles and key technologies for the monitoring, protection, and control of contemporary wide-area power systems. A variety of topical issues are addressed, including renewable energy sources, smart grids, wide-area stabilizing, coordinated voltage regulation, and angle oscillation damping—as well as the advantages of phasor measurement units (PMUs) and global positioning systems (GPS) time signal. End-of-chapter problems and solutions, along with case studies, add depth and clarity to all topics. Timely and important, Power System Monitoring and Control is an invaluable resource for addressing the myriad of critical technical engineering considerations in modern electric power system design and operation. • Provides an updated and comprehensive reference for researcher and engineers working on wide-area power system monitoring and control (PSMC) • Links fundamental concepts of PSMC, advanced metering and control theory/techniques, and practical engineering considerations • Covers PSMC problem understanding, design, practical aspects, and timely topics such as smart/microgrid control and coordinated voltage regulation and angle oscillation damping • Incorporates authors’ experiences teaching and researching in various international locales including Japan, Thailand, Singapore, Malaysia, Iran, and Australia
Roni Neff Introduction to the US Food System. Public Health, Environment, and Equity Roni Neff Introduction to the US Food System. Public Health, Environment, and Equity Новинка

Roni Neff Introduction to the US Food System. Public Health, Environment, and Equity

6118.32 руб.
A public health approach to the US food system Introduction to the US Food System: Public Health, Environment, and Equity is a comprehensive and engaging textbook that offers students an overview of today's US food system, with particular focus on the food system's interrelationships with public health, the environment, equity, and society. Using a classroom-friendly approach, the text covers the core content of the food system and provides evidence-based perspectives reflecting the tremendous breadth of issues and ideas important to understanding today's US food system. The book is rich with illustrative examples, case studies, activities, and discussion questions. The textbook is a project of the Johns Hopkins Center for a Livable Future (CLF), and builds upon the Center's educational mission to examine the complex interrelationships between diet, food production, environment, and human health to advance an ecological perspective in reducing threats to the health of the public, and to promote policies that protect health, the global environment, and the ability to sustain life for future generations. Issues covered in Introduction to the US Food System include food insecurity, social justice, community and worker health concerns, food marketing, nutrition, resource depletion, and ecological degradation. Presents concepts on the foundations of the US food system, crop production, food system economics, processing and packaging, consumption and overconsumption, and the environmental impacts of food Examines the political factors that influence food and how it is produced Ideal for students and professionals in many fields, including public health, nutritional science, nursing, medicine, environment, policy, business, and social science, among others Introduction to the US Food System presents a broad view of today's US food system in all its complexity and provides opportunities for students to examine the food system's stickiest problems and think critically about solutions.
Tim Weilkiens Model-Based System Architecture Tim Weilkiens Model-Based System Architecture Новинка

Tim Weilkiens Model-Based System Architecture

9718.01 руб.
Presents modeling approaches that can be performed in SysML and other modeling languages This book combines the emerging discipline of systems architecting with model-based approaches using SysML. The early chapters of the book provide the fundamentals of systems architecting; discussing what systems architecting entails and how it benefits systems engineering. Model-based systems engineering is then defined, and its capabilities to develop complex systems on time and in a feasible quality are discussed. The remainder of the book covers important topics such as: architecture descriptions; architecture patterns; perspectives, viewpoints, views and their relation to system architecture; the roles of a system architect, their team, and stakeholders; systems architecting processes; agile approaches to systems architecting; variant modeling techniques; architecture frameworks; and architecture assessment. The book's organization allows experts to read the chapters out of sequence. Novices can read the chapters sequentially to gain a systematic introduction to system architecting. Model-Based System Architecture: Provides comprehensive coverage of the Functional Architecture for Systems (FAS) method created by the authors and based on common MBSE practices Covers architecture frameworks, including the System of Systems, Zachman Frameworks, TOGAF®, and more Includes a consistent example system, the “Virtual Museum Tour” system, that allows the authors to demonstrate the systems architecting concepts covered in the book Model-Based System Architecture is a comprehensive reference for system architects and systems engineers in technology companies. This book will also serve as a reference to students and researchers interested in functional architectures. Tim Weilkiens is the CEO at the German consultancy oose Innovative Informatik and co-author of the SysML specification. He has introduced model-based systems engineering to a variety of industry sectors. He is author of several books about modeling and the MBSE methodology SYSMOD. Jesko G. Lamm is a Senior Systems Engineer at Bernafon, a Swiss manufacturer for hearing instruments. With Tim Weilkiens, Jesko G. Lamm founded the Functional Architectures working group of the German chapter of INCOSE. Stephan Roth is a coach, consultant, and trainer for systems and software engineering at the German consultancy oose Innovative Informatik. He is a state-certified technical assistant for computer science from Physikalisch-Technische Lehranstalt (PTL) Wedel and a certified systems engineer (GfSE)®– Level C. Markus Walker works at Schindler Elevator in the research and development division as elevator system architect. He is an INCOSE Certified Systems Engineering Professional (CSEP) and is engaged in the committee of the Swiss chapter of INCOSE.
Richard Middlestead W. Digital Communications with Emphasis on Data Modems. Theory, Analysis, Design, Simulation, Testing, and Applications Richard Middlestead W. Digital Communications with Emphasis on Data Modems. Theory, Analysis, Design, Simulation, Testing, and Applications Новинка

Richard Middlestead W. Digital Communications with Emphasis on Data Modems. Theory, Analysis, Design, Simulation, Testing, and Applications

13676.92 руб.
This book uses a practical approach in the application of theoretical concepts to digital communications in the design of software defined radio modems. This book discusses the design, implementation and performance verification of waveforms and algorithms appropriate for digital data modulation and demodulation in modern communication systems. Using a building-block approach, the author provides an introductory to the advanced understanding of acquisition and data detection using source and executable simulation code to validate the communication system performance with respect to theory and design specifications. The author focuses on theoretical analysis, algorithm design, firmware and software designs and subsystem and system testing. This book treats system designs with a variety of channel characteristics from very low to optical frequencies. This book offers system analysis and subsystem implementation options for acquisition and data detection appropriate to the channel conditions and system specifications, and provides test methods for demonstrating system performance. This book also: Outlines fundamental system requirements and related analysis that must be established prior to a detailed subsystem design Includes many examples that highlight various analytical solutions and case studies that characterize various system performance measures Discusses various aspects of atmospheric propagation using the spherical 4/3 effective earth radius model Examines Ionospheric propagation and uses the Rayleigh fading channel to evaluate link performance using several robust waveform modulations Contains end-of-chapter problems, allowing the reader to further engage with the text Digital Communications with Emphasis on Data Modems is a great resource for communication-system and digital signal processing engineers and students looking for in-depth theory as well as practical implementations.
Biao Huang Dynamic Modeling and Predictive Control in Solid Oxide Fuel Cells. First Principle and Data-based Approaches Biao Huang Dynamic Modeling and Predictive Control in Solid Oxide Fuel Cells. First Principle and Data-based Approaches Новинка

Biao Huang Dynamic Modeling and Predictive Control in Solid Oxide Fuel Cells. First Principle and Data-based Approaches

11513.42 руб.
The high temperature solid oxide fuel cell (SOFC) is identified as one of the leading fuel cell technology contenders to capture the energy market in years to come. However, in order to operate as an efficient energy generating system, the SOFC requires an appropriate control system which in turn requires a detailed modelling of process dynamics. Introducting state-of-the-art dynamic modelling, estimation, and control of SOFC systems, this book presents original modelling methods and brand new results as developed by the authors. With comprehensive coverage and bringing together many aspects of SOFC technology, it considers dynamic modelling through first-principles and data-based approaches, and considers all aspects of control, including modelling, system identification, state estimation, conventional and advanced control. Key features: Discusses both planar and tubular SOFC, and detailed and simplified dynamic modelling for SOFC Systematically describes single model and distributed models from cell level to system level Provides parameters for all models developed for easy reference and reproducing of the results All theories are illustrated through vivid fuel cell application examples, such as state-of-the-art unscented Kalman filter, model predictive control, and system identification techniques to SOFC systems The tutorial approach makes it perfect for learning the fundamentals of chemical engineering, system identification, state estimation and process control. It is suitable for graduate students in chemical, mechanical, power, and electrical engineering, especially those in process control, process systems engineering, control systems, or fuel cells. It will also aid researchers who need a reminder of the basics as well as an overview of current techniques in the dynamic modelling and control of SOFC.
David Noer M. Healing the Wounds. Overcoming the Trauma of Layoffs and Revitalizing Downsized Organizations David Noer M. Healing the Wounds. Overcoming the Trauma of Layoffs and Revitalizing Downsized Organizations Новинка

David Noer M. Healing the Wounds. Overcoming the Trauma of Layoffs and Revitalizing Downsized Organizations

2072.88 руб.
From the founder of «layoff survivor sickness» an updated edition of a book for today's downsized workforce Thoroughly revised and updated, David Noer's classic book about downsized organizations has never been more relevant. Reports of the most recent layoffs are making the front pages of our newspapers with frightening regularity. And massive downsizing continues to reshape the face of American business. But what about those who remain behind? Healing the Wounds provides an antidote to the widespread malaise on the American business scene left in the wake of workforce reductions. Drawing on case studies and original research, David M. Noer-an expert frequently quoted in major media such as The Wall Street Journal and Fortune on the topic of layoffs and layoff survivor sickness-provides executives, human resource professionals, managers, and consultants with an original model and clear guidelines for revitalizing downsized organizations and the employees left behind. Offers thoroughly revised edition of a book about layoffs and those who are left behind Filled with relevant case studies and recent research Written by David Noer an acclaimed expert on the topic Gives employers much-needed guidance for revitalizing downsized companies
Отсутствует Warnung vor jedem Nichteinigungs-System Отсутствует Warnung vor jedem Nichteinigungs-System Новинка

Отсутствует Warnung vor jedem Nichteinigungs-System

0 руб.
Полный вариант заголовка: «Warnung vor jedem Nichteinigungs-System : ein Bruchstück für den deutschen Staatsmann : an meine Mitstände».
J. States Christopher Arsenic. Exposure Sources, Health Risks, and Mechanisms of Toxicity J. States Christopher Arsenic. Exposure Sources, Health Risks, and Mechanisms of Toxicity Новинка

J. States Christopher Arsenic. Exposure Sources, Health Risks, and Mechanisms of Toxicity

14036.82 руб.
This book illustrates the chemistry, toxicology, and health effects of arsenic using novel modeling techniques, case studies, experimental data, and future perspectives. • Covers exposure sources, health risks, and mechanisms of one of the most toxic minerals in the world • Helps readers understand potential health effects of arsenic, using population studies, mammalian and invertebrate models, and pharmacokinetic and toxicokinetic models • Discusses outcomes, epidemiology, real-life examples, and modes of action for arsenic-induced diseases, like lung cancer, diabetes, cardiovascular and pulmonary diseases, and immunotoxicity • Acts as a reference for toxicologists, environmental chemists, and risk assessors and includes up-to-date, novel modeling techniques for scientists • Includes future perspectives on special topics, like extrapolation from experimental models to human exposures, biomarkers for phenotypic anchoring, and pathology of chronic exposure
Harald Gossner System Level ESD Co-Design Harald Gossner System Level ESD Co-Design Новинка

Harald Gossner System Level ESD Co-Design

10077.23 руб.
An effective and cost efficient protection of electronic system against ESD stress pulses specified by IEC 61000-4-2 is paramount for any system design. This pioneering book presents the collective knowledge of system designers and system testing experts and state-of-the-art techniques for achieving efficient system-level ESD protection, with minimum impact on the system performance. All categories of system failures ranging from 'hard' to 'soft' types are considered to review simulation and tool applications that can be used. The principal focus of System Level ESD Co-Design is defining and establishing the importance of co-design efforts from both IC supplier and system builder perspectives. ESD designers often face challenges in meeting customers' system-level ESD requirements and, therefore, a clear understanding of the techniques presented here will facilitate effective simulation approaches leading to better solutions without compromising system performance. With contributions from Robert Ashton, Jeffrey Dunnihoo, Micheal Hopkins, Pratik Maheshwari, David Pomerenke, Wolfgang Reinprecht, and Matti Usumaki, readers benefit from hands-on experience and in-depth knowledge in topics ranging from ESD design and the physics of system ESD phenomena to tools and techniques to address soft failures and strategies to design ESD-robust systems that include mobile and automotive applications. The first dedicated resource to system-level ESD co-design, this is an essential reference for industry ESD designers, system builders, IC suppliers and customers and also Original Equipment Manufacturers (OEMs). Key features: Clarifies the concept of system level ESD protection. Introduces a co-design approach for ESD robust systems. Details soft and hard ESD fail mechanisms. Detailed protection strategies for both mobile and automotive applications. Explains simulation tools and methodology for system level ESD co-design and overviews available test methods and standards. Highlights economic benefits of system ESD co-design.
Ron Schneiderman Modern Standardization. Case Studies at the Crossroads of Technology, Economics, and Politics Ron Schneiderman Modern Standardization. Case Studies at the Crossroads of Technology, Economics, and Politics Новинка

Ron Schneiderman Modern Standardization. Case Studies at the Crossroads of Technology, Economics, and Politics

6474.8 руб.
This book includes a collection of standards-specific case studies. The case studies offer an opportunity to combine the teaching preferences of educators with the goals of the SEC (Standards Education Committee); providing students with “real-world” insight into the technical, political, and economic arenas of engineering. Encourages students to think critically about standards development and technology solutions Reinforces the usage of standards as an impetus for innovation Will help understand the dynamics and impacts of standards A curriculum guide is available to instructors who have adopted the book for a course. To obtain the guide, please send a request to: [email protected]
Roy Moodley International Counseling. Case Studies Handbook Roy Moodley International Counseling. Case Studies Handbook Новинка

Roy Moodley International Counseling. Case Studies Handbook

4243.69 руб.
In this book, designed to increase mental health professionals’ global literacy, authors from 33 countries demonstrate multicultural skills and competencies through case studies that illustrate approaches to counseling and psychotherapy in their countries. Following an introductory section on the use of case studies, chapters focus on a cross section of countries in Africa; Australia and Asia; Central, North, and South America; Europe; and the Middle East. Each case describes the client and his or her presenting concerns and includes a culture-sensitive assessment and treatment plan, an analysis and critical reflection of the case, and questions for discussion. The final chapter of the text presents a comparative analysis of the cases. *Requests for digital versions from the ACA can be found on wiley.com. *To request print copies, please visit the ACA website.
Valerio Magnasco Models for Bonding in Chemistry Valerio Magnasco Models for Bonding in Chemistry Новинка

Valerio Magnasco Models for Bonding in Chemistry

11877.41 руб.
A readable little book assisting the student in understanding, in a nonmathematical way, the essentials of the different bonds occurring in chemistry. Starting with a short, self-contained,introduction, Chapter 1 presents the essential elements of the variation approach to either total or second-order molecular energies, the system of atomic units (au) necessary to simplify all mathematical expressions, and an introductory description of the electron distribution in molecules. Using mostly 2x2 Hückel secular equations, Chapter 2, by far the largest part of the book because of the many implications of the chemical bond, introduces a model of bonding in homonuclear and heteronuclear diatomics, multiple and delocalized bonds in hydrocarbons, and the stereochemistry of chemical bonds in polyatomic molecules, in a word, a model of the strong first-order interactions originating the chemical bond. In Chapter 3 the Hückel model of the linear polyene chain is used to explain the origin of band structure in the 1-dimensional crystal. Chapter 4 deals with a simple two-state model of weak interactions, introducing the reader to understand second-order electric properties of molecules and VdW bonding between closed shells. Lastly, Chapter 5 studies the structure of H-bonded dimers and the nature of the hydrogen bond, which has a strength intermediate between a VdW bond and a weak chemical bond. Besides a qualitative MO approach based on HOMO-LUMO charge transfer from an electron donor to an electron acceptor molecule, a quantitative electrostatic approach is presented yielding an electrostatic model working even at its simplest pictorial level. A list of alphabetically ordered references, author and subject indices complete the book.
Valerio Magnasco Models for Bonding in Chemistry Valerio Magnasco Models for Bonding in Chemistry Новинка

Valerio Magnasco Models for Bonding in Chemistry

12237.01 руб.
A readable little book assisting the student in understanding, in a nonmathematical way, the essentials of the different bonds occurring in chemistry. Starting with a short, self-contained,introduction, Chapter 1 presents the essential elements of the variation approach to either total or second-order molecular energies, the system of atomic units (au) necessary to simplify all mathematical expressions, and an introductory description of the electron distribution in molecules. Using mostly 2x2 Hückel secular equations, Chapter 2, by far the largest part of the book because of the many implications of the chemical bond, introduces a model of bonding in homonuclear and heteronuclear diatomics, multiple and delocalized bonds in hydrocarbons, and the stereochemistry of chemical bonds in polyatomic molecules, in a word, a model of the strong first-order interactions originating the chemical bond. In Chapter 3 the Hückel model of the linear polyene chain is used to explain the origin of band structure in the 1-dimensional crystal. Chapter 4 deals with a simple two-state model of weak interactions, introducing the reader to understand second-order electric properties of molecules and VdW bonding between closed shells. Lastly, Chapter 5 studies the structure of H-bonded dimers and the nature of the hydrogen bond, which has a strength intermediate between a VdW bond and a weak chemical bond. Besides a qualitative MO approach based on HOMO-LUMO charge transfer from an electron donor to an electron acceptor molecule, a quantitative electrostatic approach is presented yielding an electrostatic model working even at its simplest pictorial level. A list of alphabetically ordered references, author and subject indices complete the book.
Shayne Cox Gad Drug Safety Evaluation Shayne Cox Gad Drug Safety Evaluation Новинка

Shayne Cox Gad Drug Safety Evaluation

25193.07 руб.
This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including local tissue tolerance, target organ toxicity and carcinogenicity, developmental toxicity, immunogenicity, and immunotoxicity Covers the development of new small and large molecules, generics, 505(b)(2) route NDAs, and biosimilars Revises material to reflect new drug products (small synthetic, large proteins and cells, and tissues), harmonized global and national regulations, and new technologies for safety evaluation Adds almost 20% new and thoroughly updates existing content from the last edition

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Presents modeling approaches that can be performed in SysML and other modeling languages This book combines the emerging discipline of systems architecting with model-based approaches using SysML. The early chapters of the book provide the fundamentals of systems architecting; discussing what systems architecting entails and how it benefits systems engineering. Model-based systems engineering is then defined, and its capabilities to develop complex systems on time and in a feasible quality are discussed. The remainder of the book covers important topics such as: architecture descriptions; architecture patterns; perspectives, viewpoints, views and their relation to system architecture; the roles of a system architect, their team, and stakeholders; systems architecting processes; agile approaches to systems architecting; variant modeling techniques; architecture frameworks; and architecture assessment. The book's organization allows experts to read the chapters out of sequence. Novices can read the chapters sequentially to gain a systematic introduction to system architecting. Model-Based System Architecture: Provides comprehensive coverage of the Functional Architecture for Systems (FAS) method created by the authors and based on common MBSE practices Covers architecture frameworks, including the System of Systems, Zachman Frameworks, TOGAF®, and more Includes a consistent example system, the “Virtual Museum Tour” system, that allows the authors to demonstrate the systems architecting concepts covered in the book Model-Based System Architecture is a comprehensive reference for system architects and systems engineers in technology companies. This book will also serve as a reference to students and researchers interested in functional architectures. Tim Weilkiens is the CEO at the German consultancy oose Innovative Informatik and co-author of the SysML specification. He has introduced model-based systems engineering to a variety of industry sectors. He is author of several books about modeling and the MBSE methodology SYSMOD. Jesko G. Lamm is a Senior Systems Engineer at Bernafon, a Swiss manufacturer for hearing instruments. With Tim Weilkiens, Jesko G. Lamm founded the Functional Architectures working group of the German chapter of INCOSE. Stephan Roth is a coach, consultant, and trainer for systems and software engineering at the German consultancy oose Innovative Informatik. He is a state-certified technical assistant for computer science from Physikalisch-Technische Lehranstalt (PTL) Wedel and a certified systems engineer (GfSE)®– Level C. Markus Walker works at Schindler Elevator in the research and development division as elevator system architect. He is an INCOSE Certified Systems Engineering Professional (CSEP) and is engaged in the committee of the Swiss chapter of INCOSE.
Продажа drosophila melanogaster an model system for toxicity studies лучших цены всего мира
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