early use of newer agents for advanced non small cell lung cancer



Jack Roth A. Lung Cancer Jack Roth A. Lung Cancer Новинка

Jack Roth A. Lung Cancer

13568.3 руб.
The best and most concise single source for state-of-the-art diagnosis and treatment of lung cancer –newly revised, updated, and expanded. Lung cancer has long been the number-one cause of death from cancer every year and the third most frequently diagnosed after breast and prostate cancers. In 2010, about 15% of all cancer diagnoses and 30% of all cancer deaths were due to lung cancer. Needless to say, there is a great need for more rapid advancements in diagnosis and treatment of this devastating disease. Here is the comprehensively revised, updated, and expanded edition of the well-established, evidence-based reference book that deals with the most recent advances in lung cancer prevention, screening, diagnosis, research, and treatment for the clinician. Edited and authored by leading authorities in the field, this Fourth Edition of the highly regarded Lung Cancer is better than ever –featuring nine new chapters along with seven re-formatted ones that are nearly brand new in content and approach. It covers Smoking Prevention and Cessation; Molecular Profiling; Somatic Genome Alterations in Human Lung Cancers; Management of Multi-Focal Bronchioloalveolar Carcinoma (BAC); Primary Tracheal Tumors; Predictive Tumor Biomarkers for EGFR Inhibitors; Non-Small Cell and Small-Cell Lung Carcinoma; and more. This Fourth Edition of Lung Cancer: Provides the very latest research in the identification of biomarkers to predict a high risk for developing lung cancer – vital for implementing screening, diagnosis, and prevention strategies Presents the newest lung cancer staging system, as well as updated and cutting-edge surgical and radiation therapy techniques that make local tumor control more effective and less invasive while sparing normal tissues Discusses combined modality therapy and new chemotherapeutic agents which are yielding higher response rates and improved survival when used in the adjuvant setting or concurrent with highly sophisticated radiation or proton treatment Offers novel and emergent approaches to preventative, diagnostic, and therapeutic modalities with an emphasis on the best evidence available from the latest studies and clinical trials With almost half of the revised and updated content being brand new, Lung Cancer, Fourth Edition, is an important and vital resource for all medical professionals and students involved in the care and treatment of those struck with this catastrophic illness.
Ian Hunt ABC of Lung Cancer Ian Hunt ABC of Lung Cancer Новинка

Ian Hunt ABC of Lung Cancer

3498.68 руб.
Lung Cancer is the most common cause of cancer death and cancer symptoms. The ABC of Lung Cancer is a much needed reference for those treating and caring for patients with lung cancer such as primary care doctors, specialist cancer nurses, junior doctors, nurses, physiotherapists, radiographers and other health care professionals. This new title in the ABC series covers the epidemiology and diagnosis of lung cancer, focusing particularly on primary care issues such as what symptoms require urgent investigation, and when to refer to a specialist. This is a practical guide for all those involved in the care of the lung cancer patient, as well as patients and their families and carers.
Alison Leary Lung Cancer. A Multidisciplinary Approach Alison Leary Lung Cancer. A Multidisciplinary Approach Новинка

Alison Leary Lung Cancer. A Multidisciplinary Approach

2107.31 руб.
Lung Cancer: A Multidisciplinary Approach provides clinicians with a comprehensive text that can be used when caring for patients with lung cancer throughout the entire patient journey. This edited collection explores the aetiology of lung cancer; mesothelioma; the range of available treatments, including chemotherapy and radiotherapy; surgical care; supportive and end-of-life care; quality-of-life issues; and the role of the nurse within the multidisciplinary team. A comprehensive, evidence-based guide to lung cancer Illustrative case studies used throughout Contributions from respected healthcare professionals in the field Interprofessional in focus Lung Cancer: A Multidisciplinary Approach is an essential resource for all nurses and healthcare professionals working with cancer patients.
Alison Leary Lung Cancer. A Multidisciplinary Approach Alison Leary Lung Cancer. A Multidisciplinary Approach Новинка

Alison Leary Lung Cancer. A Multidisciplinary Approach

4012.34 руб.
Lung Cancer: A Multidisciplinary Approach provides clinicians with a comprehensive text that can be used when caring for patients with lung cancer throughout the entire patient journey. This edited collection explores the aetiology of lung cancer; mesothelioma; the range of available treatments, including chemotherapy and radiotherapy; surgical care; supportive and end-of-life care; quality-of-life issues; and the role of the nurse within the multidisciplinary team. A comprehensive, evidence-based guide to lung cancer Illustrative case studies used throughout Contributions from respected healthcare professionals in the field Interprofessional in focus Lung Cancer: A Multidisciplinary Approach is an essential resource for all nurses and healthcare professionals working with cancer patients.
Khalid Shah Stem Cell Therapeutics for Cancer Khalid Shah Stem Cell Therapeutics for Cancer Новинка

Khalid Shah Stem Cell Therapeutics for Cancer

12059.57 руб.
Stem Cell Therapeutics for Cancer covers the application of stem cells in various cancers, with an emphasis on the aspects of these strategies that are critical to the success of future stem cell-based therapies for cancer. Topics covered in the book include stem cell sources, tumor specificity, targeted therapeutics, visualizing the stem cell, and therapeutic agent pharmacokinetics. Each chapter contains a brief introduction to the cancer, followed by an exploration of how engineered stem cells have been utilized to cure the disease in mouse models and in early phase clinical trials. Comprises of sections on stem cell therapy in brain cancers, lung cancers, breast cancers, as well as stem cells in combination with other therapies Focuses on the practical applications of using stem cells as gene delivery agents to treat cancer Includes coverage of cutting-edge molecular imaging techniques in stem cell therapeutics for a variety of tumour types
Amanda Harvey Cancer Cell Signalling Amanda Harvey Cancer Cell Signalling Новинка

Amanda Harvey Cancer Cell Signalling

11670.81 руб.
A focused, accessible introduction to this key aspect of cancer biology. It covers the individual cell signalling pathways that are known to be involved in cancer development, and, most important, includes the cross- interactions between the pathways together with the current therapeutic approaches. This is a ‘must-have’ for advanced undergraduate and postgraduate students studying and researching within the field of cancer biology.
Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications and Therapeutics Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications and Therapeutics Новинка

Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications and Therapeutics

10941.17 руб.
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.
Vinagolu Rajasekhar K. Cancer Stem Cells Vinagolu Rajasekhar K. Cancer Stem Cells Новинка

Vinagolu Rajasekhar K. Cancer Stem Cells

14472.24 руб.
Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.
Robert A. Meyers Translational Medicine. Cancer, 2 Volume Set Robert A. Meyers Translational Medicine. Cancer, 2 Volume Set Новинка

Robert A. Meyers Translational Medicine. Cancer, 2 Volume Set

34293.18 руб.
The first complete overview of progress in the field. The two volumes contain selected articles from the prestigious online Encyclopedia of Molecular Cell Biology and Molecular Medicine, fully updated and enriched with numerous new contributions from many eminent scientists. Divided into three parts, the first gives a thorough introduction to cancer biology, while Part Two covers therapeutic approaches for all major forms of cancer, and the third part deals with cancer diagnostics. The result is a one-stop resource for advanced students, postdoctoral researchers and start-up companies.
Sudhir Srivastava Biomarkers in Cancer Screening and Early Detection Sudhir Srivastava Biomarkers in Cancer Screening and Early Detection Новинка

Sudhir Srivastava Biomarkers in Cancer Screening and Early Detection

10941.17 руб.
Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information ? and hopefully also inspiration ? to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers
Richard Hobbs ABC of Colorectal Cancer Richard Hobbs ABC of Colorectal Cancer Новинка

Richard Hobbs ABC of Colorectal Cancer

2550.29 руб.
Colorectal cancer is a common cause of morbidity and mortality in which prevention, screening and early detection are vital. Beginning with the patient perspective and following the patient pathway, this new second edition covers epidemiology and prevention, screening programmes, decision support networks, the role of primary care, and supportive care for patients with colorectal cancer. The ABC of Colorectal Cancer provides the core knowledge on clinical genetics, diagnosis, imaging, therapy and surgery options and the latest evidence based guidelines for treating and managing colorectal cancer patients within the multidisciplinary team. Highly illustrated and accessible, it covers the full spectrum of the disease to provide the basis to make a real difference to clinical management. This is an invaluable practical guide for the non-specialist on all aspects of colorectal cancer, and is ideal for general practitioners, junior doctors, nurses and allied health professionals.
Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors Новинка

Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors

11305.99 руб.
Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.
Sharmila Bapat A. Cancer Stem Cells. Identification and Targets Sharmila Bapat A. Cancer Stem Cells. Identification and Targets Новинка

Sharmila Bapat A. Cancer Stem Cells. Identification and Targets

8289.78 руб.
Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology – two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.
Kun Cheng Advanced Drug Delivery Kun Cheng Advanced Drug Delivery Новинка

Kun Cheng Advanced Drug Delivery

9412.66 руб.
Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.
Crump Kenneth Cancer Chemotherapy for the Veterinary Health Team Crump Kenneth Cancer Chemotherapy for the Veterinary Health Team Новинка

Crump Kenneth Cancer Chemotherapy for the Veterinary Health Team

4372.33 руб.
Cancer Chemotherapy for the Veterinary Health Team is a clinically relevant and practical manual designed as a guide for the safe and effective administration of cancer chemotherapy. Coverage includes patient assessment, chemotherapy equipment, drug preparation, safety considerations, handling, administration, waste disposal, and management of chemotherapy side effects. An alphabetical listing of common chemotherapy agents offers information on their uses, indications, and toxicities, as well as administration guidelines for methods, routes, and speeds. With background information for effectively communicating with clients, including coverage of veterinary cancer surgery and radiation therapy, the book provides specific strategies that address the challenging emotional issues surrounding the diagnosis and treatment of cancer in pets. With particular insight into the technician's role, Cancer Chemotherapy for the Veterinary Health Team is a must-have reference for any practice offering chemotherapy.
Stella Pelengaris The Molecular Biology of Cancer. A Bridge from Bench to Bedside Stella Pelengaris The Molecular Biology of Cancer. A Bridge from Bench to Bedside Новинка

Stella Pelengaris The Molecular Biology of Cancer. A Bridge from Bench to Bedside

11674.96 руб.
The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. “Bench to Bedside”: A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients – essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: An overview of the cancer cell and important new concepts. Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. Chapters highlighting the direct links between cancer research and clinical applications. New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Quotations have been used in each chapter to introduce basic concepts in an entertaining way. Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: “A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology…..This book deserves great praise for the readable presentation of this complex field….the true synthesis of bench and bedside approaches is marvelously achieved.” Christian Schmidt, Molecular Cell “Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references….This book is applicable to both graduate and undergraduate students, and in the context of a
Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration Новинка

Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration

12035.63 руб.
A much-needed primer on the use of laser flow cytometry for stem cell analysis Laser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods and staining procedures based on specific characteristics such as marker expression, cell size, drug transport, and efflux of the stem cells. Now, this book reviews these procedures, discusses the science behind them, and provides real-world examples to illustrate the usefulness of the methods. It brings together world-class experts in pathology, biophysics, immunology, and stem cell research, who draw upon their extensive experience with the methods and show examples of good data to help guide researchers in the right direction. Chapter coverage includes: Stem cell analysis and sorting using side population Flow cytometry in the study of proliferation and apoptosis Stem cell biology and application Identification and isolation of very small embryonic-like stem cells from murine and human specimens Hematopoietic stem cells—issues in enumeration Human embryonic stem cells: long-term culture and cardiovascular differentiation Limbal stem cells and corneal regeneration Flow cytometric sorting of spermatogonial stem cells Breast cancer stem cells Stem cell marker expression in cells from body cavity fluids This book is an essential resource for all graduate students, practitioners in developing countries, libraries and book repositories of universities and research institutions, and individual researchers. It is also of interest to laboratories engaged in stem cell research and use of stem cells for tissue regeneration, and to any organization dealing in stem cell and tissue regeneration research.
Haines Simon, Hewings Martin, Nettle Mark Advanced Grammar in Use Supplementary Exercises: With answers Haines Simon, Hewings Martin, Nettle Mark Advanced Grammar in Use Supplementary Exercises: With answers Новинка

Haines Simon, Hewings Martin, Nettle Mark Advanced Grammar in Use Supplementary Exercises: With answers

560 руб.
Advanced Grammar in Use Supplementary Exercises contains 50 units of varied exercises to provide students with additional practice of the language they have studied in Advanced Grammar in Use 2nd edition.
Ashutosh Tiwari Advanced Theranostic Materials Ashutosh Tiwari Advanced Theranostic Materials Новинка

Ashutosh Tiwari Advanced Theranostic Materials

14228.71 руб.
The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications
Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals Новинка

Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals

5578.67 руб.
Over 99% of the world's population is infected with at least one potentially cancer-causing organism. It is vital for nurses and other healthcare professionals to be aware of the extent of infection-associated cancer and of how they can contribute to prevention of such cancers. Infectious Causes of Cancer, aimed principally at nurses and other healthcare professionals, considers the epidemiology and biology of infectious causes of cancer. It examines each of the infectious agents associated with an increased risk of cancer, discussing epidemiology of the infection and cancer, pathophysiology of the cancer, mechanisms, associated risk factors, and prevention of the infection and cancer. Key Features: A comprehensive and accessible guide to infection associated cancer and how to contribute to prevention A must-have for students or healthcare professionals working in oncology, primary care or health promotion Brings together all the up-to-date science, evidence and research related to infections and cancer in one publication
Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications Новинка

Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications

13279.62 руб.
Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA – quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes – sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis – aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis – β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.
Martine Piccart-Gebhart Holland-Frei Cancer Medicine Martine Piccart-Gebhart Holland-Frei Cancer Medicine Новинка

Martine Piccart-Gebhart Holland-Frei Cancer Medicine

21885.8 руб.
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Bartley Trish Mindfulness-Based Cognitive Therapy for Cancer. Gently Turning Towards Bartley Trish Mindfulness-Based Cognitive Therapy for Cancer. Gently Turning Towards Новинка

Bartley Trish Mindfulness-Based Cognitive Therapy for Cancer. Gently Turning Towards

8817.55 руб.
Mindfulness-based Cognitive Therapy for Cancer presents an eight-week course for MBCT which has been tried and tested over ten years of clinical use, and is targeted specifically for people with cancer. There is growing evidence of mindfulness as a successful and cost-effective intervention for reducing the negative psychological impact of cancer and treatment Draws upon the author’s experience of working with people with cancer, and her own recent experience of using mindfulness with cancer diagnosis and treatment Stories from cancer patients illustrate the learning and key themes of the course Includes new short practices and group processes developed by the author
Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy Новинка

Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy

5837.14 руб.
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive – and how they can be turned into potent weapons against it – is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
Stephen Wiviott D. Antiplatelet Therapy In Ischemic Heart Disease Stephen Wiviott D. Antiplatelet Therapy In Ischemic Heart Disease Новинка

Stephen Wiviott D. Antiplatelet Therapy In Ischemic Heart Disease

12059.57 руб.
This book in the new American Heart Association Clinical Series, explores and explains state-of-the-art use of antiplatelet agents and draws on the expertise of global leaders in antiplatelet therapy. Skillfully organized for fast reference, the book is divided into five parts: Concepts in Platelet Physiology, Function, and Measurement Pharmacology of Oral Antiplatelet Agents Pharmacology of Intravenous Antiplatelet Agents Clinical Use of Antiplatelet Agents in Cardiovascular Disease Special Circumstances. Each chapter in the clinical section contains an overview of guidelines, plus specifics on medical and interventional uses. Clinical cardiologists, platelet biologists, and a wide range of practicing and prospective clinicians in allied fields will find this text an exceptional source of current information.
Bruce Thompson R. Interpreting Lung Function Tests. A Step-by Step Guide Bruce Thompson R. Interpreting Lung Function Tests. A Step-by Step Guide Новинка

Bruce Thompson R. Interpreting Lung Function Tests. A Step-by Step Guide

4519.77 руб.
Lung function assessment is the central pillar of modern respiratory diagnosis, providing invaluable information to assist in clinical decision making and management strategies.Interpreting Lung Function Tests: A Step-by Step Guide is a practical “how-to” training manual, which provides the reader with the necessary skills to interpret lung function test results, and to write a concise and informative report on the outcome. Interpreting Lung Function Tests: A Step-by Step Guide provides unique guidance on the reporting of pulmonary function tests, including illustrative cases and sample reports. utilizes the many references available on interpretation of lung function and provides a teaching/reference tool for report writing of lung function results routinely performed in clinical practice. provides the reader with the skill to interpret and write a concise, yet informative report provides examples of results and written reports (with commentary where necessary as further explanation). focuses primarily on tests performed as part of routine clinical testing: spirometry, static lung volumes, gas transfer, bronchial provocation tests, and maximal respiratory pressures. Interpreting Lung Function Tests: A Step-by Step Guideis a superb new resource to educate medical students, junior doctors, family physicians, as well as advanced trainee physicians specializing in respiratory medicine, respiratory scientists, and respiratory physicians
Daniel Lednicer Antineoplastic Drugs. Organic Syntheses Daniel Lednicer Antineoplastic Drugs. Organic Syntheses Новинка

Daniel Lednicer Antineoplastic Drugs. Organic Syntheses

9850.86 руб.
The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry.
Bailey Christopher D. Cancer Nursing. Care in Context Bailey Christopher D. Cancer Nursing. Care in Context Новинка

Bailey Christopher D. Cancer Nursing. Care in Context

7915.94 руб.
The needs of cancer patients and their families are complex. Yet still more complex are the powerful social and cultural forces that shape the delivery of cancer care, and the way in which it experienced. Cancer Nursing: Care in Context addresses this by adopting a unique approach that situates cancer care in the context of society‘s attitudes to the disease, and the broader every-day needs of both patients and their carers. By combining evidenced-based information, a critical view of care and treatment, and ‘first-hand accounts’ of having cancer and caring for people with cancer, the book provides a new perspective how best to deliver the care that patients truly require. This second edition includes new chapters on prevention, diagnosis, symptoms, self-help and self-management, and living with cancer long-term. It also: • Addresses significant changes in cancer care, including expansion of nursing roles, the establishment of cancer networks and cancer collaborative projects • Considers NICE guidance on Supportive and Palliative care • Incorporates material on prevention and early detection • Includes evidence tables based on relevant literature Cancer Nursing: Care in Context is an invaluable resource for all those involved in the provision of cancer care and support to patients and their families.
Mauricio Rojas Molecular Aspects of Aging. Understanding Lung Aging Mauricio Rojas Molecular Aspects of Aging. Understanding Lung Aging Новинка

Mauricio Rojas Molecular Aspects of Aging. Understanding Lung Aging

9773.33 руб.
Molecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence. Covering universal themes in aging, such as the exhaustion of stem cells and subsequent loss of the regenerative refueling of organs as well as immunosenescence, this text illuminates new directions for research not yet explored in the still poorly investigated area of molecular mechanisms of lung aging. The molecular nature of general aging processes is explored with targeted coverage on how to analyze lung aging through experimental approaches.
John Deutsch C. Gastrointestinal Endoscopy in the Cancer Patient John Deutsch C. Gastrointestinal Endoscopy in the Cancer Patient Новинка

John Deutsch C. Gastrointestinal Endoscopy in the Cancer Patient

15975.28 руб.
Are you involved in the diagnosis and management of patients with gastrointestinal cancer Gastrointestinal Endoscopy in the Cancer Patient provides you with a full color, highly clinical, multi-media tool focused on the role diagnostic and therapeutic endoscopy plays in the management of patients with cancer. With chapters authored by the world’s leading endoscopy and oncology experts and edited by a highly experienced editor team, you’ll find a level of clinical excellence that is unsurpassed in other books on this topic. Covering GI cancer from both the perspective of the gastroenterologist and the oncologist, it contains approximately 400 quality color images and 21 high-definition videos showing endoscopy being performed by the experts. Conveniently split into sections for each part of the GI tract, including the esophagus, stomach, upper GI, lower GI, pancreas and liver/biliary system, each section follows a consistent structure of: Diagnosis and Staging of premalignant and malignant conditions Endoscopic management of premalignant and early malignant diseases Palliation of advanced tumors Oncologist’s perspective Gastrointestinal Endoscopy in the Cancer Patient is a must-have purchase and perfect consultation and learning tool for all gastroenterologists, endoscopists, GI surgeons and oncologists involved in the diagnosis and management of patients with gastrointestinal cancer.
Sanford Moskowitz L. Advanced Materials Innovation. Managing Global Technology in the 21st century Sanford Moskowitz L. Advanced Materials Innovation. Managing Global Technology in the 21st century Новинка

Sanford Moskowitz L. Advanced Materials Innovation. Managing Global Technology in the 21st century

10944.63 руб.
Through detailed case studies of the most important advanced material creations of the latter 20th and early 21st century, the author explores the role of the field of advanced materials in the technological and economic activity today, with implications to the innovation process in general. A comprehensive study that encompasses the three major categories of advanced material technologies, i.e., Structural Materials (metals and polymers), Functional Materials (transistor, microchip and semiconductor laser) and Hybrid and New Forms of Matter (liquid crystals and nanomaterials). Extensive use of primary sources, including unpublished interviews with the scientists, engineers, and entrepreneurs on the front lines of advanced materials creation Original approach to case study narrative, emphasizing interaction between the advanced material process, perceived risk and directing and accelerating breakthrough technology
Ashutosh Tiwari Advanced Biomaterials and Biodevices Ashutosh Tiwari Advanced Biomaterials and Biodevices Новинка

Ashutosh Tiwari Advanced Biomaterials and Biodevices

14662.07 руб.
This cutting-edge book focuses on the emerging area of biomaterials and biodevices that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities The design and development of biomaterials play a significant role in the diagnosis, treatment, and prevention of diseases. When used with highly selective and sensitive biomaterials, cutting-edge biodevices can allow the rapid and accurate diagnosis of disease, creating a platform for research and development, especially in the field of treatment for prognosis and detection of diseases in the early stage. This book emphasizes the emerging area of biomaterials and biodevices that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. The 15 comprehensive chapters written by leading experts cover such topics as: The use of severe plastic deformation technique to enhance the properties of nanostructured metals Descriptions of the different polymers for use in controlled drug release Chitin and chitosan as renewable healthcare biopolymers for biomedical applications Innovated devices such as “label-free biochips” and polymer MEMS Molecular imprinting and nanotechnology Prussian Blue biosensing applications The evaluation of different types of biosensors in terms of their cost effectiveness, selectivity, and sensitivity Stimuli-responsive polypeptide nanocarriers for malignancy therapeutics
Ashutosh Tiwari Advanced Surfaces for Stem Cell Research Ashutosh Tiwari Advanced Surfaces for Stem Cell Research Новинка

Ashutosh Tiwari Advanced Surfaces for Stem Cell Research

16417.64 руб.
The book outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells. In the following chapters the influence of biological, chemical, mechanical, and physical properties of surfaces in micro and nano-scale on stem cell behavior are discussed including the mechanotransduction. Biomimetic and bioinspired approaches are highlighted for developing microenvironment of several tissues, and surface engineering applications are discussed in tissue engineering, regenerative medicine and different type of biomaterials in various chapters of the book. This book brings together innovative methodologies and strategies adopted in the research and development of Advanced Surfaces in Stem Cell Research. Well-known worldwide researchers deliberate subjects including: Extracellular matrix proteins for stem cell fate The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator Effects of mechanotransduction on stem cell behavior Modulation of stem cells behavior through bioactive surfaces Influence of controlled micro and nanoengineered surfaces on stem cell fate Nanostructured polymeric surfaces for stem cells Laser surface modification techniques and stem cells applications Plasma polymer deposition: a versatile tool for stem cell research Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments Substrates and surfaces for control of pluripotent stem cell fate and function Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering Silk as a natural biopolymer for tissue engineering
Hewings Martin Advanced Grammar in Use. With answers Hewings Martin Advanced Grammar in Use. With answers Новинка

Hewings Martin Advanced Grammar in Use. With answers

2178 руб.
A Self-Study Reference and Practice Book for Advanced Learners of English. Advanced Grammar in Use second edition is a fully updated version of the successful grammar title. The new edition focuses on the complexities of grammatical choices important for an advanced understanding of English. This new edition: - contains 100 units of grammar reference and practice materials including seven completely NEW units - Includes NEW additional exercises, appendices and coverage more specifically aimed at the advanced learner - has a comprehensive Basic Grammar Reference to allow learners to check language areas they have already studied - is informed by the Cambridge International Corpus to ensure the language is authentic and up-to-date - provides ideal support for students preparing for Cambridge Advanced Examination in English, Cambridge Proficiency or the IELTS examination 3d Edition.
Maurie Markman Cancer Nutrition and Recipes For Dummies Maurie Markman Cancer Nutrition and Recipes For Dummies Новинка

Maurie Markman Cancer Nutrition and Recipes For Dummies

1444.46 руб.
Fight cancer from the inside out Cancer treatments such as surgery, chemotherapy, and radiation can be as hard on the body as the disease itself, and detailed nutritional advice is usually not part of the program. Yet eating the right foods can actually help lessen the strength of some of the most powerful symptoms of cancer and the side effects of treatment, allowing the patient to better fight the disease. Now, Cancer Nutrition & Recipes For Dummies is your trusted, informative guide to fighting cancer from the inside out. Designed for cancer patients and their families, Cancer Nutrition & Recipes For Dummies focuses on foods best tolerated during—and that can ease side effects of—cancer treatment. It also offers advice for menu planning, nutritional analysis, diabetic exchanges, and much more. Serves as a guide for cancer nutrition before, during, and after treatment Gives you a wealth of easy, immediate steps to speed up the healing process through diet Offers advice on treatment as well as solutions to common side effects like dehydration, fatigue, and nausea Enables cancer patients to put their strongest foot forward when starting treatment Cancer Nutrition & Recipes For Dummies targets those dealing with cancer and the loved ones who take care of them, aiding both parties in alleviating some of the side effects of the cancer treatment through change in diet.
Gosney Margot Cancer and Aging Handbook. Research and Practice Gosney Margot Cancer and Aging Handbook. Research and Practice Новинка

Gosney Margot Cancer and Aging Handbook. Research and Practice

10777.84 руб.
A state-of-the-art, multidisciplinary approach to cancer and aging With the majority of cancers occurring in individuals over the age of 65 against a backdrop of an expanding aging population, there is an urgent need to integrate the areas of clinical oncology and geriatric care. This timely work tackles these issues head-on, presenting a truly multidisciplinary and international perspective on cancer and aging from world-renowned experts in geriatrics, oncology, behavioral science, psychology, gerontology, and public health. Unlike other books on geriatric oncology that focus mainly on treatment, Cancer and Aging Handbook: Research and Practice examines all phases of the cancer care continuum, from prevention through evidence-based diagnosis and treatment to end-of-life care. Detailed clinical and research information helps guide readers on effective patient care as well as caregiver training, research, and intervention. Coverage includes: Epidemiology of cancer in older adults, plus the unique physical, mental, and social issues involved Strategies and guidelines for prevention, screening, and treatment of older individuals with cancer The most common cancers in the elderly, including breast, colorectal, lung, prostate, and ovarian cancer Cancer survivorship in older adults as well as the all-critical issues of palliative care and pain management Emerging topics such as caregiver and family issues, different models of care, and cost considerations An essential resource for clinicians and caregivers as well as researchers interested in this evolving field, Cancer and Aging Handbook is also useful for public health professionals and policymakers who need to formulate services and allocate resources for the growing population of older cancer patients.
Michelle Turek M. Decision Making in Small Animal Oncology Michelle Turek M. Decision Making in Small Animal Oncology Новинка

Michelle Turek M. Decision Making in Small Animal Oncology

7003.59 руб.
Decision Making in Small Animal Oncology is a practical manual for the increasing number of veterinarians called upon to treat patients with cancer. This case-based quick reference leads practitioners through diagnosis, treatment, and management decisions, offering reliable guidance for more effective management of cancer care. With easy-to-follow algorithms to assist the reader through the critical thinking process, Decision Making in Small Animal Oncology answers the questions most commonly asked in daily practice to provide the cancer knowledge practitioners and students need in general practice.
Heide Schatten Cell and Molecular Biology and Imaging of Stem Cells Heide Schatten Cell and Molecular Biology and Imaging of Stem Cells Новинка

Heide Schatten Cell and Molecular Biology and Imaging of Stem Cells

11682.59 руб.
Cell and Molecular Biology and Imaging of Stem Cells features original and review articles written by experts who have made significant contributions to stem cell biology and imaging. Chapters cover a broad spectrum of aspects of the field, including Stem cells from the Amniotic Fluid and Placenta, Biomaterials as Artificial Niches for Pluripotent Stem Cell Engineering, Low-Intensity Ultrasound in Stem Cells and Tissue Engineering, Mammalian Neo-Oogenesis from Ovarian Stem Cells, Oct4-EGFP Transgenic Pigs as a New Tool for Visualization of Pluripotent and Reprogrammed Cells, Regulation of Adult Intestinal Stem Cells, Stem Cell Therapy for Veterinary Orthopedic Lesions, Sex Steroid Combinations in Regenerative Medicine for Brain and Heart Diseases, Hair Follicle Stem Cells, The Potential of Using Induced Pluripotent Stem Cells in Skin Diseases, Mitochondrial Differentiation in Early Embryo Cells and Pluripotent Stem Cells, and The Role of Centrosomes in Cancer Stem Cell Functions. Cell and Molecular Biology and Imaging of Stem Cells addresses a wide variety of cell and molecular topics in unprecedented detail, and is a must-read for graduate students and academic and industry professionals in the expanding field of stem cell biology. Reviews new imaging tools and markers for cell and molecular imaging in stem cell biology. Covers novel aspects of stem cell imaging in reproductive biology and stem cell niches Includes chapters on the developing area of centrosome biology as it applies to embryonic and adult stem differentiation
Vaux David Cell Death Vaux David Cell Death Новинка

Vaux David Cell Death

13265.91 руб.
This book on cell death contains 29 self-contained, peer-reviewed articles written by leading scientists in each field. It features overview articles aimed at undergraduates and non-specialists, which present basic information and provide entry into the following advanced articles. These advanced articles are written for postgraduate students and research workers, containing detailed information and key references allowing the reader to investigate a specific area in more depth. The book is an essential resource for educational purposes as well as a reference work for experienced researchers in the field. The articles will also be available electronically as part of the acclaimed Encyclopedia of Life Sciences (ELS). Key features: Provides a comprehensive overview on the research of programmed cell death. Edited by leaders in the field. Clearly written and illustrated articles. Full colour throughout. A spin-on to the acclaimed reference work, the Encyclopedia of Life Science (ELS). Combines introductory information with coverage of the latest discoveries in the field. Features overview level articles for advanced students or people new to a topic and more advanced articles for those requiring more detailed information. Serves as a reference work for advanced students as well as researchers in this field. Ideal library purchase for science, medical, and technology libraries in academia, government, and industry; medical libraries; networks and consortia covering these markets.
Yusuke Hiraku Cancer and Inflammation Mechanisms. Chemical, Biological, and Clinical Aspects Yusuke Hiraku Cancer and Inflammation Mechanisms. Chemical, Biological, and Clinical Aspects Новинка

Yusuke Hiraku Cancer and Inflammation Mechanisms. Chemical, Biological, and Clinical Aspects

9412.66 руб.
A new perspective on the link between inflammation and cancer Inflammation is the human body’s normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and sustained for long periods of time? Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects discusses the mechanisms by which chronic inflammation can lead to cancer, the various causative agents, and possible prevention methods. A compilation of the latest information coming out of the various fields of cancer research, this book provides a detailed look at inflammation-related carcinogenesis from the perspective of researchers at the forefront of the field. It takes an interdisciplinary approach to the topic, and provides comprehensive information about the major factors at work in inflammation, cancer, and the intersection of the two conditions. Topics include: A general overview of inflammation-related cancer The biochemistry of inflammation and its effects on DNA Molecular biology and the role of microRNA in carcinogenesis Specific causative agents including oncogenic viruses, asbestos, and nanomaterial Anti-inflammatories, nutraceuticals, and other preventative measures A deeper understanding of the mechanisms behind inflammation-related carcinogenesis can lead to better patient outcomes by improving diagnostics and prevention, as well as altering the approach to treatment. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects provides the knowledge base researchers need to push the field forward.
Printio Agents of chaos Printio Agents of chaos Новинка

Printio Agents of chaos

1290 руб.
Футболка с полной запечаткой для девочек.
Hugo Kubinyi Protein-Protein Interactions in Drug Discovery Hugo Kubinyi Protein-Protein Interactions in Drug Discovery Новинка

Hugo Kubinyi Protein-Protein Interactions in Drug Discovery

15322.48 руб.
Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the development pipeline of major pharmaceutical companies to illustrate the power and potential of this approach. From the contents: * Prediction of intra- and inter-species protein-protein interactions facilitating systems biology studies * Modulators of protein-protein interactions: The importance of Three-Dimensionality * Interactive technologies for leveraging the known chemistry of anchor residues * SH3 Domains as Drug Targets * P53 MDM2 Antagonists: Towards Non Genotoxic Anticancer Treatments * Inhibition of LFA-1/ICAM interaction for treatment of autoimmune diseases * The PIF-binding pocket of AGC kinases * Peptidic inhibitors of protein-protein interactions for cell adhesion receptors * The REPLACE Strategy for generating Non-ATP competitive Inhibitors of Cell-Cycle Protein Kinases and more
Printio Agents of chaos Printio Agents of chaos Новинка

Printio Agents of chaos

1290 руб.
Футболка с полной запечаткой для мальчиков.
Barry Sheila A. Cancer. Basic Science and Clinical Aspects Barry Sheila A. Cancer. Basic Science and Clinical Aspects Новинка

Barry Sheila A. Cancer. Basic Science and Clinical Aspects

7762.01 руб.
“… Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams… a useful book for the undergraduate medical or allied health professional…” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.
Christian Wittekind TNM Atlas Christian Wittekind TNM Atlas Новинка

Christian Wittekind TNM Atlas

8318.2 руб.
The complete, authoritative TNM cancer classification and staging system—now illustrated with new, full-colour figures for fast, effective, anatomical referencing Referring to “Tumour,” “Node,” and “Metastasis,” the TNM system is the most widely used means for classifying and staging the extent of cancer spread. Published in affiliation with the Union for International Cancer Control (UICC), TNM Atlas, Sixth Edition presents the illustrated version of the TNM Classification of Malignant Tumours, Seventh Edition, promoting the uniform application of the TNM classification in cancer practice. Utilizing beautiful, full-colour medical artwork—illustrating the T and N categories in clear, easily understood graphics—this book aides in the practical application of the TNM classification system. It enables all disciplines involved in cancer classification, staging, and treatment to reach a more standardized understanding and documentation of the anatomical spread of tumours, and further enhances the dissemination and use of the TNM classification. The TNM Atlas, Sixth Edition: • Is based upon the very latest TNM Classification data available in TNM Classification of Malignant Tumours, Seventh Edition • Features over 500 full-colour figures that clearly illustrate and highlight anatomical sites of cancer involvement • Makes TNM classification even more clinically applicable in the day-to-day environment • Is an extremely useful tool for clinical reference, teaching, discussion, and patient education Based in Geneva, the UICC is one of the most widely affiliated cancer organisations in the world, with its core mission being cancer classification and control. Its TNM Atlas, Sixth Edition is a valuable reference for all medical, surgical, and radiation oncologists, anatomical and surgical pathologists, cancer registrars, oncology nurses and physician extenders, international cancer care centres, and governmental and NGOs dedicated to cancer control. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play.
J. Davim Paulo Sustainable Manufacturing J. Davim Paulo Sustainable Manufacturing Новинка

J. Davim Paulo Sustainable Manufacturing

8896.71 руб.
According to the NACFAM (National Council for Advanced Manufacturing USA) Sustainable Manufacturing is defined as the creation of manufactured products that use processes that are non-polluting, conserve energy and natural resources, and are economically sound and safe for employees, communities, and consumers. The book covers Sustainable Manufacturing techniques such as materials and manufacturing for renewable energies; clean manufacturing technology; ecological manufacturing; energy-efficient manufacturing; remanufacturing; recycling of materials; environmentally conscious design and manufacturing processes; sustainable advanced manufacturing systems; manufacturability in sustainable product design; education and training for sustainable manufacturing.
Andre Richardt CBRN Protection. Managing the Threat of Chemical, Biological, Radioactive and Nuclear Weapons Andre Richardt CBRN Protection. Managing the Threat of Chemical, Biological, Radioactive and Nuclear Weapons Новинка

Andre Richardt CBRN Protection. Managing the Threat of Chemical, Biological, Radioactive and Nuclear Weapons

7588.55 руб.
Originating in the armed forces of the early 20th century, weapons based on chemical, biological or nuclear agents have become an everpresent threat that has not vanished after the end of the cold war. Since the technology to produce these agents is nowadays available to many countries and organizations, including those with terrorist aims, civil authorities across the world need to prepare against incidents involving these agents and train their personnel accordingly. As an introductory text on NBC CBRN weapons and agents, this book leads the reader from the scientific basics to the current threats and strategies to prepare against them. After an introductory part on the history of NBC CBRN weapons and their international control, the three classes of nuclear/radiological, biological, and chemical weapons are introduced, focusing on agents and delivery vehicles. Current methods for the rapid detection of NBC CBRN agents are introduced, and the principles of physical protection of humans and structures are explained. The final parts addresses more general issues of risk management, preparedness and response management, as the set of tools that authorities and civil services will be needed in a future CBRN scenario as well as the likely future scenarios that authorities and civil services will be faced with in the coming years. This book is a must-have for Health Officers, Public Health Agencies, and Military Authorities.
Prokar Dasgupta ABC of Prostate Cancer Prokar Dasgupta ABC of Prostate Cancer Новинка

Prokar Dasgupta ABC of Prostate Cancer

2987.79 руб.
Prostate cancer is the most common cancer in men in the UK and US and the second most common worldwide. The ABC of Prostate Cancer provides fully illustrated guidance on the treatment and management of prostate cancer. It covers the biology, anatomy, and pathology of prostate cancer, screening, and active surveillance and monitoring. It presents an assessment of treatment options including prostatectomy, bracytherapy, chemotherapy and immunotherapy, along with modern diagnostic tests and an overview of new approaches to prostate cancer. With an international author team, the ABC of Prostate Cancer is ideal for general practitioners, family physicians, specialist nurses, junior doctors, medical students and others working with prostate cancer patients and their families.
Mrityunjay Singh Advanced Processing and Manufacturing Technologiesfor Structural and Multifunctional Materials VI Mrityunjay Singh Advanced Processing and Manufacturing Technologiesfor Structural and Multifunctional Materials VI Новинка

Mrityunjay Singh Advanced Processing and Manufacturing Technologiesfor Structural and Multifunctional Materials VI

6417.25 руб.
The 6th International Symposium on Advanced Processing and Manufacturing Technologies for Structural and Multifunctional Materials and Systems was held in January 2012 during the 36th International Conference and Exposition on Advanced Ceramics and Composites. This symposium examined progress resulting from the research and development of advanced processing and manufacturing technologies for a wide variety of non-oxide and oxide-based structural ceramics, particulate and fiber-reinforced composites, and multifunctional materials. This issue features seventeen of those papers, representing some of the most important developments in processing and manufacturing technologies.
Rosalind Eeles A. Cancer Prevention and Screening. Concepts, Principles and Controversies Rosalind Eeles A. Cancer Prevention and Screening. Concepts, Principles and Controversies Новинка

Rosalind Eeles A. Cancer Prevention and Screening. Concepts, Principles and Controversies

9420.72 руб.
Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques
Shayne Cox Gad Development of Therapeutic Agents Handbook Shayne Cox Gad Development of Therapeutic Agents Handbook Новинка

Shayne Cox Gad Development of Therapeutic Agents Handbook

21110.85 руб.
A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings together, in one resource, a compendium of concepts, approaches, methodologies, and limitations that need to be considered in the formulation of therapeutic agents across a range of therapeutic fields. Both a reference and a call to action for the pharmaceutical industry, Development of Therapeutic Agents Handbook examines recent innovations taking shape in the various medical disciplines involved in drug discovery, and shows why these advances need to be embraced universally among researchers to improve their solution strategies. Additional subject matter includes: Extensive coverage and in-depth look into novel treatments and therapeutics Discussion of hot topics like new drugs and nutraceuticals, the discovery and development of vaccines, cancer therapeutics, and market overviews Coverage of therapeutic drug development for specific disease areas, such as cardiology, oncology, breast cancer, and kidney diseases As research in biology, chemistry, medicine, and technology rapidly progresses, it is becoming increasingly important for medical researchers to maintain an up-to-date knowledge base of emerging trends directing promising new therapies. Development of Therapeutic Agents Handbook serves this purpose, acting as both a one-stop reference rich in valid science, and a tool to carve out new pathways in the pursuit of bringing safer and more effective drugs to the marketplace.
Rob Burgess Stem Cells. A Short Course Rob Burgess Stem Cells. A Short Course Новинка

Rob Burgess Stem Cells. A Short Course

6563.32 руб.
Stem Cells: A Short Course is a comprehensive text for students delving into the rapidly evolving discipline of stem cell research. Comprised of eight chapters, the text addresses all of the major facets and disciplines related to stem cell biology and research. A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells. The book concludes with chapters on stem cell applications, including the role of stem cells in drug discovery and therapeutic applications in spinal cord injury, brain damage, neurological and autoimmune disorders, among others. Written by a leader in the field, Stem Cells: A Short Course appeals to both students and instructors alike, appealing to academic enthusiasm for stem cell research and applications.
Peter Whelan Prostate Cancer. Diagnosis and Clinical Management Peter Whelan Prostate Cancer. Diagnosis and Clinical Management Новинка

Peter Whelan Prostate Cancer. Diagnosis and Clinical Management

7803.85 руб.
Do you manage patients with prostate cancer? Could you use an expert guide examining all possible management options? Prostate Cancer: diagnosis and clinical management providesurologists and oncologists of all levels with up-to-date, evidence-based guidance to the diagnosis, treatment and clinical management of a disease which accounts for a quarter of all cancers affecting men. Designed to be as practical and accessible as possible, leading experts discuss key issues in prostate cancer management and examine how to deliver best practice in the clinical care of their patients. Topics covered include: What must be considered when counseling newly-diagnosed cancer patients Radical surgery options for prostate cancer Novel therapies for localized prostate cancer How should metastatic prostate cancer be diagnostic and managed What are the best methods of administering end of life care for the patient Brought to you by a highly experienced editor team, and containing key points, management algorithms, practice tips and the latest AUA and EAU clinical guidelines, this is the ideal consultation tool for doctors both on the wards and in the office.
O`Dell Felicity English Idioms in Use Advanced 2 Edition with ans O`Dell Felicity English Idioms in Use Advanced 2 Edition with ans Новинка

O`Dell Felicity English Idioms in Use Advanced 2 Edition with ans

2460 руб.
Improve your understanding of idioms in English. Explanations and practice of English idioms, written for advanced-level (C1 to C2) learners of English. Perfect for both self-study and classroom activities. Learn idioms in context, with lots of different topics, including 'Learning', 'Formal writing' and 'Telling stories'. Be confident about what you are learning, thanks to Cambridge research into how English is really spoken and written, and get better at studying by yourself, with study tips, follow-up tasks and an easy to use answer key.
Ashutosh Tiwari Advanced Healthcare Materials Ashutosh Tiwari Advanced Healthcare Materials Новинка

Ashutosh Tiwari Advanced Healthcare Materials

14662.07 руб.
Advanced materials are attracting strong interest in the fundamental as well as applied sciences and are being extensively explored for their potential usage in a range of healthcare technological and biological applications. Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices. The book highlights the key features which enable engineers to design stimuli-responsive smart nanoparticles, novel biomaterials, nano/micro-devices for diagnosis, therapy (theranostics).The leading contributor researchers cover the following topics: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers The book is written for readers from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering. It offers a comprehensive view of cutting-edge research on advanced materials for healthcare technology and applications.
Norman Sartorius Depression and Cancer Norman Sartorius Depression and Cancer Новинка

Norman Sartorius Depression and Cancer

4449.85 руб.
Recently, there has been a growing awareness of the multiple interrelationships between depression and cancer. Depression and Cancer is devoted to the interaction between these disorders. The book examines various aspects of this comorbidity and describes how the negative consequences of depression in cancer could be avoided or ameliorated, given that effective depression treatments for cancer patients are available. Renowned psychiatrists and oncologists summarize the latest evidence on the epidemiology, pathogenesis, screening and recognition, and cultural and public health implications of depression in persons with cancer, among other topics.
Hewings Martin Advanced Grammar in Use with answers (+CD) Hewings Martin Advanced Grammar in Use with answers (+CD) Новинка

Hewings Martin Advanced Grammar in Use with answers (+CD)

1387 руб.
Издание полностью на английском языке. Book DescriptionA fully updated version of the highly successful Advanced Grammar in Use - extra practice is also available on a new interactive CD-ROM to accompany the book. This is the edition with answers.

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The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. “Bench to Bedside”: A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients – essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: An overview of the cancer cell and important new concepts. Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. Chapters highlighting the direct links between cancer research and clinical applications. New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Quotations have been used in each chapter to introduce basic concepts in an entertaining way. Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: “A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology…..This book deserves great praise for the readable presentation of this complex field….the true synthesis of bench and bedside approaches is marvelously achieved.” Christian Schmidt, Molecular Cell “Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references….This book is applicable to both graduate and undergraduate students, and in the context of a
Продажа early use of newer agents for advanced non small cell lung cancer лучших цены всего мира
Посредством этого сайта магазина - каталога товаров мы очень легко осуществляем продажу early use of newer agents for advanced non small cell lung cancer у одного из интернет-магазинов проверенных фирм. Определитесь с вашими предпочтениями один интернет-магазин, с лучшей ценой продукта. Прочитав рекомендации по продаже early use of newer agents for advanced non small cell lung cancer легко охарактеризовать производителя как превосходную и доступную фирму.