in search of safety – chemicals amp cancer risk



Peter Fisk Chemical Risk Assessment. A Manual for REACH Peter Fisk Chemical Risk Assessment. A Manual for REACH Новинка

Peter Fisk Chemical Risk Assessment. A Manual for REACH

7739.59 руб.
This book is an essential guide and support to understanding of the science and policy, procedure and practice that underpins the REACH risk assessments required for the use and placing on the market of chemicals in the European Union. A clear understanding of information provision and how this affects the assessment of chemical safety is fundamentally important to the success of policy on chemicals and ultimately to the sustainability of the chemicals industry. Within the book, the scientific processes that underpin the policy are explained in a practical way. Importantly, it includes coverage of techniques to help solve the problems of using potentially risky and hazardous chemicals through the use of less hazardous alternatives and ‘green chemistry’, and also the analysis of the risks of the use of the most hazardous substances against the social and economic benefits of use. Chemical Risk Assessment: A Manual for REACH covers the following main themes: i) Assessment of chemical risk; ii) Risk management; iii) Hazard reduction, substitution and green chemistry; iv) Risk versus benefit – socio-economic analysis. The book acts as a practical guide and overview to chemicals risk assessment and risk management (in the EU context), as well as a support text for planning for the challenges of the future, which will see ever-increasing pressure to withdraw hazardous substances from the EU (and global) market, balanced against opportunities for innovation in the development of less hazardous chemicals.
Gunter Obe Cancer Risk Evaluation. Methods and Trends Gunter Obe Cancer Risk Evaluation. Methods and Trends Новинка

Gunter Obe Cancer Risk Evaluation. Methods and Trends

8969.22 руб.
An overview of the different approaches to cancer risk assessment of environmental factors – including «-omics» technologies, discussing the strengths and weaknesses of the methods in different fields. The main focus is on the carcinogenic effects of ionizing and non-ionizing radiation, demonstrating the difficulties in accurately assessing those factors that may or may not pose a significant cancer risk. The book extends the view to a broader context of risk assessment, highlighting various aspects of risk management. Written by leading experts in the field, this is a resource for policy makers and professionals in health risk assessment, and public health workers, as well as oncologists and researchers in academia. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
Vladimir Rykov Reliability of Engineering Systems and Technological Risk Vladimir Rykov Reliability of Engineering Systems and Technological Risk Новинка

Vladimir Rykov Reliability of Engineering Systems and Technological Risk

9407.93 руб.
This book is based on a lecture course to students specializing in the safety of technological processes and production. The author focuses on three main problems in technological risks and safety: elements of reliability theory, the basic notions, models and methods of general risk theory and some aspects of insurance in the context of risk management. Although the material in this book is aimed at those working towards a bachelor's degree in engineering, it may also be of interest to postgraduate students and specialists dealing with problems related to reliability and risks.
David Carpenter O. Effects of Persistent and Bioactive Organic Pollutants on Human Health David Carpenter O. Effects of Persistent and Bioactive Organic Pollutants on Human Health Новинка

David Carpenter O. Effects of Persistent and Bioactive Organic Pollutants on Human Health

9826.48 руб.
Examines what we know about the relationship between organic chemicals and human disease Organic chemicals are everywhere: in the air we breathe, the water we drink, and the food we eat. They are also found in a myriad of common household and personal care products. Unfortunately, exposure to some organic chemicals can result in adverse health effects, from growth and developmental disorders to cancer and neurodegenerative diseases. This book examines how organic chemicals affect human health. It looks at the different diseases as well as how individual organ systems are affected by organic chemicals. Effects of Persistent and Bioactive Organic Pollutants on Human Health begins with an introductory chapter explaining why we should care about organic chemicals and their effect on human health. Next, the authors address such important topics as: Burden of cancer from organic chemicals Organic chemicals and obesity Effects of organic chemicals on the male reproductive system Organic chemicals and the immune system Intellectual developmental disability syndromes and organic chemicals Mental illness and exposure to organic chemicals The book ends with an assessment of how much human disease is caused by organic chemicals. Chapters have been contributed by leading international experts in public and environmental health and are based on the latest research findings. Readers will find that all of the contributions are clear and easy to comprehend, with extensive references for further investigation of individual topics. Effects of Persistent and Bioactive Organic Pollutants on Human Health is recommended for students and professionals in medicine as well as public and environmental health, bringing them fully up to date with what we know about the relationship between organic chemicals and human health.
Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals Новинка

Kenneth Campbell Infectious Causes of Cancer. A Guide for Nurses and Healthcare Professionals

5466.75 руб.
Over 99% of the world's population is infected with at least one potentially cancer-causing organism. It is vital for nurses and other healthcare professionals to be aware of the extent of infection-associated cancer and of how they can contribute to prevention of such cancers. Infectious Causes of Cancer, aimed principally at nurses and other healthcare professionals, considers the epidemiology and biology of infectious causes of cancer. It examines each of the infectious agents associated with an increased risk of cancer, discussing epidemiology of the infection and cancer, pathophysiology of the cancer, mechanisms, associated risk factors, and prevention of the infection and cancer. Key Features: A comprehensive and accessible guide to infection associated cancer and how to contribute to prevention A must-have for students or healthcare professionals working in oncology, primary care or health promotion Brings together all the up-to-date science, evidence and research related to infections and cancer in one publication
Eisenbrand G. Risk Assessment of Phytochemicals in Food. Novel Approaches Eisenbrand G. Risk Assessment of Phytochemicals in Food. Novel Approaches Новинка

Eisenbrand G. Risk Assessment of Phytochemicals in Food. Novel Approaches

15663.26 руб.
Providing the scientific background on the risk and safety assessment of toxicity in phytochemicals in everyday food, this monograph contains the pros and cons of 20 testing methods, with comments by the internationally acknowledged and independent DFG Senate Commission on Food Safety. Supplemented by 40 poster contributions on phytochemicals and their effects.
Nicholas Cheremisinoff P. Perfluorinated Chemicals (PFCs). Contaminants of Concern Nicholas Cheremisinoff P. Perfluorinated Chemicals (PFCs). Contaminants of Concern Новинка

Nicholas Cheremisinoff P. Perfluorinated Chemicals (PFCs). Contaminants of Concern

16282.46 руб.
This new volume provides a timely study on the environmental challenges from a specific class of perfluorinated chemical compounds (PFCs) that are now being recognized as a worldwide health threat. Recent studies report that levels of classes of PFCs known as polyfluoroalkyl and perfluoroalkyl (PFASs) exceed federally recommended safety levels in public drinking-water supplies for 6 million people in the United States and that as many as 100 million people could be at risk from exposure to these chemicals. These chemicals occur globally in wildlife and humans. Both PFCAs and PFSAs have been produced for more than 50 years, but have only become of interest to regulators and environmentalists since the late 1990s. Recent advances in analytical methodology has enabled widespread detection in the environment and humans at trace levels. These toxic chemicals have been found in outdoor and indoor air, surface and drinking water, house dust, animal tissue, human blood serum, and human breast milk. Of great concern to communities is the presence of these compounds in a number of drinking water supplies in the U.S. and other countries. This new volume provides a timely explanation of the chemicals, provides a detailed review of the regulations both in the US and European Community, explains the health risk literature, and then explores in great detail available treatment technologies. The volume is a must for public water supply facilities, industrial operations that have historically used these chemicals and face legacy pollution issues, policy makers and the general public.
Timothy Veenstra D. Proteomic Applications in Cancer Detection and Discovery Timothy Veenstra D. Proteomic Applications in Cancer Detection and Discovery Новинка

Timothy Veenstra D. Proteomic Applications in Cancer Detection and Discovery

6719.68 руб.
Helps researchers in proteomics and oncology work together to understand, prevent, and cure cancer Proteomic data is increasingly important to understanding the origin and progression of cancer; however, most oncologic researchers who depend on proteomics for their studies do not collect the data themselves. As a result, there is a knowledge gap between scientists, who devise proteomic techniques and collect the data, and the oncologic researchers, who are expected to interpret and apply proteomic data. Bridging the gap between proteomics and oncology research, this book explains how proteomic technology can be used to address some of the most important questions in cancer research. Proteomic Applications in Cancer Detection and Discovery enables readers to understand how proteomic data is acquired and analyzed and how it is interpreted. Author Timothy Veenstra has filled the book with examples—many based on his own firsthand research experience—that clearly demonstrate the application of proteomic technology in oncology research, including the discovery of novel biomarkers for different types of cancers. The book begins with a brief introduction to systems biology, explaining why cancer is a systems biology disease. Next, it covers such topics as: Mass spectrometry in cancer research Application of proteomics to global phosphorylation analysis Search for biomarkers in biofluids Rise and fall of proteomic patterns for cancer diagnostics Emergence of protein arrays Role of proteomics in personalized medicine The final chapter is dedicated to the future prospects of proteomics in cancer research. By guiding readers through the latest proteomic technologies and their applications in cancer research, Proteomic Applications in Cancer Detection and Discovery enhances the ability of researchers in proteomics and researchers in oncology to collaborate in order to better understand cancer and develop strategies to prevent and treat it.
Georgi Popov Risk Assessment. A Practical Guide to Assessing Operational Risks Georgi Popov Risk Assessment. A Practical Guide to Assessing Operational Risks Новинка

Georgi Popov Risk Assessment. A Practical Guide to Assessing Operational Risks

9045.43 руб.
Covers the fundamentals of risk assessment and emphasizes taking a practical approach in the application of the techniques Written as a primer for students and employed safety professionals covering the fundamentals of risk assessment and emphasizing a practical approach in the application of the techniques Each chapter is developed as a stand-alone essay, making it easier to cover a subject Includes interactive exercises, links, videos, and downloadable risk assessment tools Addresses criteria prescribed by the Accreditation Board for Engineering and Technology (ABET) for safety programs
Sorochty Roger W. Risk Management in Student Affairs. Foundations for Safety and Success Sorochty Roger W. Risk Management in Student Affairs. Foundations for Safety and Success Новинка

Sorochty Roger W. Risk Management in Student Affairs. Foundations for Safety and Success

4063.58 руб.
A comprehensive, accessible guide to the policies and practices of risk management in higher education Student affairs staff at all types of colleges and universities need to be equipped to help manage risk and protect their institutions, the people they serve, and their resources from unintended consequences. Risk Management in Student Affairs: Foundations for Safety and Success helps practitioners understand the sources of risk in their work, and the practices and strategies they can employ to help mitigate that risk. Written for those without legal training, the book is accessible to new and mid-level professionals as well as students preparing to enter the profession. It teaches how to limit, control, and respond to risk in order to protect oneself and one's institution. The book covers all aspects of risk management in higher education, including: Tort liability (such as damage due to negligence, accidents on campus, injuries resulting from alcohol use, and incidents during study-abroad trips) Contracts (such as off-campus incidents, contracts for events and activities, and employment and disciplinary issues) State and federal violations (including the freedoms of speech, religion, and the press, search and seizure, due process, OSHA, Title IX, FERPA, and ADA) Resource protection (including information and data security, facilities, financial resources, and physical environments) Managing risk is an integral part of the work of student affairs, and the ability to manage risk well can save time, money, and personnel at a time when resources can be scarce. Whether you work in a public or private institution, and whether you manage personal or institutional risk, no other book addresses risk management within higher education in such a focused, comprehensive manner.
Laura Robinson A Practical Guide to Toxicology and Human Health Risk Assessment Laura Robinson A Practical Guide to Toxicology and Human Health Risk Assessment Новинка

Laura Robinson A Practical Guide to Toxicology and Human Health Risk Assessment

7975.08 руб.
Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning … especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author’s training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.
Wiley-VCH Ullmann's Fine Chemicals Wiley-VCH Ullmann's Fine Chemicals Новинка

Wiley-VCH Ullmann's Fine Chemicals

51348.88 руб.
A compilation of 76 articles from the ULLMANN's Encyclopedia of Industrial Chemistry, this three-volume handbook contains a wealth of information on the production and industrial use of more than 2,000 of the most important fine chemicals, from «Alcohols» to «Urea Derivatives». Chemical and physical characteristics, production processes and production figures, main uses, toxicology and safety information are all found here in one single resource.
McCormick Norman J. Risk and Safety Analysis of Nuclear Systems McCormick Norman J. Risk and Safety Analysis of Nuclear Systems Новинка

McCormick Norman J. Risk and Safety Analysis of Nuclear Systems

10122.01 руб.
The book has been developed in conjunction with NERS 462, a course offered every year to seniors and graduate students in the University of Michigan NERS program. The first half of the book covers the principles of risk analysis, the techniques used to develop and update a reliability data base, the reliability of multi-component systems, Markov methods used to analyze the unavailability of systems with repairs, fault trees and event trees used in probabilistic risk assessments (PRAs), and failure modes of systems. All of this material is general enough that it could be used in non-nuclear applications, although there is an emphasis placed on the analysis of nuclear systems. The second half of the book covers the safety analysis of nuclear energy systems, an analysis of major accidents and incidents that occurred in commercial nuclear plants, applications of PRA techniques to the safety analysis of nuclear power plants (focusing on a major PRA study for five nuclear power plants), practical PRA examples, and emerging techniques in the structure of dynamic event trees and fault trees that can provide a more realistic representation of complex sequences of events. The book concludes with a discussion on passive safety features of advanced nuclear energy systems under development and approaches taken for risk-informed regulations for nuclear plants.
Terje Aven Misconceptions of Risk Terje Aven Misconceptions of Risk Новинка

Terje Aven Misconceptions of Risk

6439.93 руб.
We all face risks in a variety of ways, as individuals, businesses and societies. The discipline of risk assessment and risk management is growing rapidly and there is an enormous drive for the implementation of risk assessment methods and risk management in organizations. There are great expectations that these tools provide suitable frameworks for obtaining high levels of performance and balance different concerns such as safety and costs. The analysis and management of risk are not straightforward. There are many challenges. The risk discipline is young and there area a number of ideas, perspectives and conceptions of risk out there. For example many analysts and researchers consider it appropriate to base their risk management policies on the use of expected values, which basically means that potential losses are multiplied with their associated consequences. However, the rationale for such a policy is questionable. A number of such common conceptions of risk are examined in the book, related to the risk concept, risk assessments, uncertainty analyses, risk perception, the precautionary principle, risk management and decision making under uncertainty. The Author discusses these concepts, their strenghts and weaknesses, and concludes that they are often better judged as misconceptions of risk than conceptions of risk. Key Features: Discusses common conceptions of risk with supporting examples. Provides recommendations and guidance to risk analysis and risk management. Relevant for all types of applications, including engineering and business. Presents the Author’s overall conclusions on the issues addressed throughout the book. All those working with risk-related problems need to understand the fundamental ideas and concepts of risk. Professionals in the field of risk, as well as researchers and graduate sutdents will benefit from this book. Policy makers and business people will also find this book of interest.
Terje Aven Misconceptions of Risk Terje Aven Misconceptions of Risk Новинка

Terje Aven Misconceptions of Risk

6575.61 руб.
We all face risks in a variety of ways, as individuals, businesses and societies. The discipline of risk assessment and risk management is growing rapidly and there is an enormous drive for the implementation of risk assessment methods and risk management in organizations. There are great expectations that these tools provide suitable frameworks for obtaining high levels of performance and balance different concerns such as safety and costs. The analysis and management of risk are not straightforward. There are many challenges. The risk discipline is young and there area a number of ideas, perspectives and conceptions of risk out there. For example many analysts and researchers consider it appropriate to base their risk management policies on the use of expected values, which basically means that potential losses are multiplied with their associated consequences. However, the rationale for such a policy is questionable. A number of such common conceptions of risk are examined in the book, related to the risk concept, risk assessments, uncertainty analyses, risk perception, the precautionary principle, risk management and decision making under uncertainty. The Author discusses these concepts, their strenghts and weaknesses, and concludes that they are often better judged as misconceptions of risk than conceptions of risk. Key Features: Discusses common conceptions of risk with supporting examples. Provides recommendations and guidance to risk analysis and risk management. Relevant for all types of applications, including engineering and business. Presents the Author’s overall conclusions on the issues addressed throughout the book. All those working with risk-related problems need to understand the fundamental ideas and concepts of risk. Professionals in the field of risk, as well as researchers and graduate sutdents will benefit from this book. Policy makers and business people will also find this book of interest.
Kristi Funk Breasts: An Owner’s Manual: Every Woman’s Guide to Reducing Cancer Risk, Making Treatment Choices and Optimising Outcomes Kristi Funk Breasts: An Owner’s Manual: Every Woman’s Guide to Reducing Cancer Risk, Making Treatment Choices and Optimising Outcomes Новинка

Kristi Funk Breasts: An Owner’s Manual: Every Woman’s Guide to Reducing Cancer Risk, Making Treatment Choices and Optimising Outcomes

687.93 руб.
A revolutionary and definitive new approach to preventing breast cancer, from Board-certified world authority on breast health Dr. Kristi Funk, co-founder of the renowned Pink Lotus Breast Centre, and surgeon to Angelina Jolie and Sheryl Crow.Breasts: An Owner’s Manual is a straight-talking, myth and misconception-busting, strategy-filled guide to breast health. Sharing the latest on lifestyle choices that impact your risk factor including food, supplements, hormones and exercise, Dr. Funk demonstrates that you are so much more in control of whether or not you get breast cancer than you could ever dare to think.In fact, unless you carry a genetic mutation associated with breast cancer, the choices you make in your-day-to-day life trumps genetics and family history when it comes to breast cancer risk, every time.Including a unique long-term risk reduction plan for every woman based on her needs, as well as the latest on diagnosis and treatment for women living with and surviving breast cancer, and with a heartfelt Foreword from longtime patient Sheryl Crow, this is a book with a life-saving message for the 1 in 8 women, at the time of writing, who are set to be diagnosed in their lifetime.
Antonio Giordano Cancer Epigenetics. Biomolecular Therapeutics in Human Cancer Antonio Giordano Cancer Epigenetics. Biomolecular Therapeutics in Human Cancer Новинка

Antonio Giordano Cancer Epigenetics. Biomolecular Therapeutics in Human Cancer

11936.53 руб.
Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and aims to facilitate collaboration between the basic, translational, and clinical sciences.
Lundgren Regina E. Risk Communication. A Handbook for Communicating Environmental, Safety, and Health Risks Lundgren Regina E. Risk Communication. A Handbook for Communicating Environmental, Safety, and Health Risks Новинка

Lundgren Regina E. Risk Communication. A Handbook for Communicating Environmental, Safety, and Health Risks

6498.03 руб.
A fully updated handbook on effectively communicating environmental, safety, and health risks Written by two well-known risk practitioners with over twenty-five years' experience in the field, this fully updated Fifth Edition of Risk Communication: A Handbook for Communicating Environmental, Safety, and Health Risks offers sound, scientific research with practical, hands-on advice for those in the public and private sectors. Highly accessible and easy to understand, this must-read includes real-life examples of such headline-making events as the tsunami and radiation release in Japan in 2011, the BP oil disaster in the Gulf of Mexico in 2010, and extreme weather events, along with the lessons learned from them. It offers new chapters on public health campaigns, and on the use and effectiveness of social media for risk communication purposes. Risk Communication is divided into five self-contained parts: Part I provides background information for understanding the basic theories and practices of risk communication Part II explains how to plan a risk communication effort Part III describes how to put risk communication into action Part IV discusses how to evaluate risk communication efforts, including techniques for measuring success Part V highlights special cases in risk communication, including disasters and other emergencies, international risk communication, and public health campaigns An ideal introduction to the field, this book is also a welcome reference for those involved in communicating environmental, safety, and health risks in government, industry, and academia.
Bailey Christopher D. Cancer Nursing. Care in Context Bailey Christopher D. Cancer Nursing. Care in Context Новинка

Bailey Christopher D. Cancer Nursing. Care in Context

7757.13 руб.
The needs of cancer patients and their families are complex. Yet still more complex are the powerful social and cultural forces that shape the delivery of cancer care, and the way in which it experienced. Cancer Nursing: Care in Context addresses this by adopting a unique approach that situates cancer care in the context of society‘s attitudes to the disease, and the broader every-day needs of both patients and their carers. By combining evidenced-based information, a critical view of care and treatment, and ‘first-hand accounts’ of having cancer and caring for people with cancer, the book provides a new perspective how best to deliver the care that patients truly require. This second edition includes new chapters on prevention, diagnosis, symptoms, self-help and self-management, and living with cancer long-term. It also: • Addresses significant changes in cancer care, including expansion of nursing roles, the establishment of cancer networks and cancer collaborative projects • Considers NICE guidance on Supportive and Palliative care • Incorporates material on prevention and early detection • Includes evidence tables based on relevant literature Cancer Nursing: Care in Context is an invaluable resource for all those involved in the provision of cancer care and support to patients and their families.
Martine Piccart-Gebhart Holland-Frei Cancer Medicine Martine Piccart-Gebhart Holland-Frei Cancer Medicine Новинка

Martine Piccart-Gebhart Holland-Frei Cancer Medicine

21705.59 руб.
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Pavel Shevchenko V. Advances in Heavy Tailed Risk Modeling. A Handbook of Operational Risk Pavel Shevchenko V. Advances in Heavy Tailed Risk Modeling. A Handbook of Operational Risk Новинка

Pavel Shevchenko V. Advances in Heavy Tailed Risk Modeling. A Handbook of Operational Risk

11578.83 руб.
A cutting-edge guide for the theories, applications, and statistical methodologies essential to heavy tailed risk modeling Focusing on the quantitative aspects of heavy tailed loss processes in operational risk and relevant insurance analytics, Advances in Heavy Tailed Risk Modeling: A Handbook of Operational Risk presents comprehensive coverage of the latest research on the theories and applications in risk measurement and modeling techniques. Featuring a unique balance of mathematical and statistical perspectives, the handbook begins by introducing the motivation for heavy tailed risk processes in high consequence low frequency loss modeling. With a companion, Fundamental Aspects of Operational Risk and Insurance Analytics: A Handbook of Operational Risk, the book provides a complete framework for all aspects of operational risk management and includes: Clear coverage on advanced topics such as splice loss models, extreme value theory, heavy tailed closed form loss distributional approach models, flexible heavy tailed risk models, risk measures, and higher order asymptotic approximations of risk measures for capital estimation An exploration of the characterization and estimation of risk and insurance modelling, which includes sub-exponential models, alpha-stable models, and tempered alpha stable models An extended discussion of the core concepts of risk measurement and capital estimation as well as the details on numerical approaches to evaluation of heavy tailed loss process model capital estimates Numerous detailed examples of real-world methods and practices of operational risk modeling used by both financial and non-financial institutions Advances in Heavy Tailed Risk Modeling: A Handbook of Operational Risk is an excellent reference for risk management practitioners, quantitative analysts, financial engineers, and risk managers. The book is also a useful handbook for graduate-level courses on heavy tailed processes, advanced risk management, and actuarial science.
Pavel Shevchenko V. Fundamental Aspects of Operational Risk and Insurance Analytics. A Handbook of Operational Risk Pavel Shevchenko V. Fundamental Aspects of Operational Risk and Insurance Analytics. A Handbook of Operational Risk Новинка

Pavel Shevchenko V. Fundamental Aspects of Operational Risk and Insurance Analytics. A Handbook of Operational Risk

11940.65 руб.
A one-stop guide for the theories, applications, and statistical methodologies essential to operational risk Providing a complete overview of operational risk modeling and relevant insurance analytics, Fundamental Aspects of Operational Risk and Insurance Analytics: A Handbook of Operational Risk offers a systematic approach that covers the wide range of topics in this area. Written by a team of leading experts in the field, the handbook presents detailed coverage of the theories, applications, and models inherent in any discussion of the fundamentals of operational risk, with a primary focus on Basel II/III regulation, modeling dependence, estimation of risk models, and modeling the data elements. Fundamental Aspects of Operational Risk and Insurance Analytics: A Handbook of Operational Risk begins with coverage on the four data elements used in operational risk framework as well as processing risk taxonomy. The book then goes further in-depth into the key topics in operational risk measurement and insurance, for example diverse methods to estimate frequency and severity models. Finally, the book ends with sections on specific topics, such as scenario analysis; multifactor modeling; and dependence modeling. A unique companion with Advances in Heavy Tailed Risk Modeling: A Handbook of Operational Risk, the handbook also features: Discussions on internal loss data and key risk indicators, which are both fundamental for developing a risk-sensitive framework Guidelines for how operational risk can be inserted into a firm’s strategic decisions A model for stress tests of operational risk under the United States Comprehensive Capital Analysis and Review (CCAR) program A valuable reference for financial engineers, quantitative analysts, risk managers, and large-scale consultancy groups advising banks on their internal systems, the handbook is also useful for academics teaching postgraduate courses on the methodology of operational risk.
Michael Toma The Risk of Trading. Mastering the Most Important Element in Financial Speculation Michael Toma The Risk of Trading. Mastering the Most Important Element in Financial Speculation Новинка

Michael Toma The Risk of Trading. Mastering the Most Important Element in Financial Speculation

4617.71 руб.
Develop the skills to manage risk in the high-stakes world of financial speculation The Risk of Trading is a practical resource that takes an in-depth look at one of the most challenging factors of trading—risk management. The book puts a magnifying glass on the issue of risk, something that every trader needs to understand in order to be successful. Most traders look at risk in terms of a «stop-loss» that enables them to exit a losing trade quickly. In The Risk of Trading, Michael Toma explains that risk is ever-present in every aspect of trading and advocates that traders adopt a more comprehensive view of risk that encompasses the strategic trading plan, account size, drawdowns, maximum possible losses, psychological capital, and crisis management. Shows how to conduct a detailed statistical analysis of an individual's trading methodology through back-testing and real-time results so as to identify when the methodology may be breaking down in actual trading Reveals why traders should think of themselves as project managers who are strategically managing risk The book is based on the author's unique 'focus on the risk' approach to trading using data-driven risk statistical analytics Using this book as a guide, traders can operate more as business managers and learn how to avoid market-busting losses while achieving consistently good results.
Frances Cowell Crisis Wasted?. Leading Risk Managers on Risk Culture Frances Cowell Crisis Wasted?. Leading Risk Managers on Risk Culture Новинка

Frances Cowell Crisis Wasted?. Leading Risk Managers on Risk Culture

4002.01 руб.
Effective risk management in today’s ever-changing world Crisis Wasted? Leading Risk Managers on Risk Culture sheds light on today’s risk management landscape through a unique collection of interviews from risk leaders in both the banking and investment industries. These interviews zero in on the risk culture of organisations, effective risk management in practice, and the sometimes paradoxical effects of new regulations and how they affect decision-making in financial organisations They offer genuine insight into regulatory processes and priorities and their implications for the stability of the global financial system. As trending topics in the risk management field, each of these subject areas is relevant to the work of today’s risk management professionals. In addition to the forward-focused text, this reference provides access to a wealth of premium online content. Risk management has become an area of focus for companies since the financial crises that shook the international community over the past decade, but, despite high levels of introspection and changes to key processes, many financial houses are still experiencing large losses. Understanding today’s risk environment can help you improve risk management tactics. Access essential information both in print and online Discover the most important topics in today’s risk management field Explore interviews with 1 risk management leaders Learn about ground-breaking recent innovations in risk management thinking Crisis Wasted? Leading Risk Managers on Risk Culture is an integral resource for professionals responsible for minimising organisational risk, as well as those who want to better understand the risk culture of today’s world.
Tony Merna Managing Risk in Construction Projects Tony Merna Managing Risk in Construction Projects Новинка

Tony Merna Managing Risk in Construction Projects

5861.85 руб.
Investment in any new project invariably carries risk but the construction industry is subject to more risk and uncertainty than perhaps any other industry. This guide for construction managers, project managers and quantity surveyors as well as for students shows how the risk management process improves decision-making. Managing Risk in Construction Projects offers practical guidance on identifying, assessing and managing risk and provides a sound basis for effective decision-making in conditions of uncertainty. The book focuses on theoretical aspects of risk management but also clarifies procedures for undertaking and utilising decisions. This blend of theory and practice is the real message of the book and, with a strong authorship team of practitioners and leading academics, the book provides an authoritative guide for practitioners having to manage real projects. It discusses a number of general concepts, including projects, project phases, and risk attitude before introducing various risk management techniques. This third edition has been extended to recognize the reality of multi-project or programme management and the risks in this context; to highlight the particular problems of risk in international joint ventures; and to provide more coverage of PFI and PPP. With case studies and examples of good practice, the book offers the distilled knowledge of over 100 man-years of experience in working on all aspects of project risk, giving sound practical guidance on identifying, assessing and managing risk.
Sharmila Bapat A. Cancer Stem Cells. Identification and Targets Sharmila Bapat A. Cancer Stem Cells. Identification and Targets Новинка

Sharmila Bapat A. Cancer Stem Cells. Identification and Targets

8123.47 руб.
Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology – two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.
Ostrom Lee T. Risk Assessment. Tools, Techniques, and Their Applications Ostrom Lee T. Risk Assessment. Tools, Techniques, and Their Applications Новинка

Ostrom Lee T. Risk Assessment. Tools, Techniques, and Their Applications

7310.75 руб.
All the tools needed to perform a thorough risk assessment—whether you're working in insurance, forensics, engineering, or public safety Risk analysis is the method of analyzing the dangers to individuals, businesses, and government agencies posed by potential natural and man-made hazards. The central task of the risk assessor is predicting the success of a project. This includes isolating the entire spectrum of adverse events that can derail a project or threaten the health and safety of individuals, organizations, and the environment. Designed as a practical, in-the-field toolkit, Risk Assessment details every aspect of how a risk assessment is performed, showing the proper tool to be used at various steps in the process, as well as locating the tool that best fits the risk assessment task at hand. Examining not only the very nature of risks and consequences, with fascinating historical examples, the book progresses from simple to more complex risk assessment techniques used by the authors in their daily work, all presented in a form that can be readily adapted to any number of real-life situations: Ecological Risk Assessment Task Analysis Techniques Preliminary Hazards Analysis Failure Mode and Effects Analysis Human Reliability Analysis Critical Incident Technique With numerous industry-specific case studies, as well as additional case studies for risk assessments for a restaurant and a process plant, the book provides readers with complete examples of how each of the techniques can be used in a variety of real-world situations. Including downloadable worksheets and other useful assessment materials, as well as guidance on using PRA software, this unparalleled reference offers all the tools and techniques needed to conduct a thorough and accurate assessment of risk.
Schwartz Donald Corporate Boards. Managers of Risk, Sources of Risk Schwartz Donald Corporate Boards. Managers of Risk, Sources of Risk Новинка

Schwartz Donald Corporate Boards. Managers of Risk, Sources of Risk

9453.37 руб.
Corporate Boards: Managers of Risk, Sources of Risk deals with the highly timely topic of the Corporate Board and its relationship to risk, both in terms of its management and its creation. Utilizes a multi-disciplinary perspective which draws on the fields of economics, law, business ethics, and corporate social responsibility Features a range of topics including the role of corporate boards in overseeing increasingly complex risk management techniques and the ethical dimensions of corporate board behavior in managing risk Of interest to students, scholars, and firm stakeholders Explores how recent events have also shown that the members of Corporate Boards can be sources of risk
Krishnan Kannan Quantitative Modeling in Toxicology Krishnan Kannan Quantitative Modeling in Toxicology Новинка

Krishnan Kannan Quantitative Modeling in Toxicology

14185.59 руб.
Governments around the world are passing laws requiring industry to assess the toxicity of the chemicals and products they produce, but to do so while reducing, refining, or even replacing testing on animals. To meet these requirements, experimental toxicologists and risk assessors are adopting quantitative approaches and computer simulations to study the biological fate and effects of chemicals and drugs. In Quantitative Modeling in Toxicology leading experts outline the current state of knowledge on the modeling of dose, tissue interactions and tissue responses. Each chapter describes the mathematical foundation, parameter estimation, challenges and perspectives for development, along with the presentation of a modeling template. Additionally, tools and approaches for conducting uncertainty, sensitivity and variability analyses in these models are described. Topics covered include: the quantitative models of pharmacokinetics of individual chemicals and mixtures models for toxicant-target tissue interaction. models for cellular, organ, and organism responses. approaches, tools and challenges for model application and evaluation A website containing computer codes accompanies the book to help the reader reconstruct the models described and discussed in the various chapters. Quantitative Modeling in Toxicology serves as an essential reference source and tool box for risk assessors and researchers and students in toxicology, public health, pharmacology, and human toxicology interested in developing quantitative models for a better understanding of dose-response relationships.
Wei Chen Financial Risk Management. Applications in Market, Credit, Asset and Liability Management and Firmwide Risk Wei Chen Financial Risk Management. Applications in Market, Credit, Asset and Liability Management and Firmwide Risk Новинка

Wei Chen Financial Risk Management. Applications in Market, Credit, Asset and Liability Management and Firmwide Risk

5849.09 руб.
A global banking risk management guide geared toward the practitioner Financial Risk Management presents an in-depth look at banking risk on a global scale, including comprehensive examination of the U.S. Comprehensive Capital Analysis and Review, and the European Banking Authority stress tests. Written by the leaders of global banking risk products and management at SAS, this book provides the most up-to-date information and expert insight into real risk management. The discussion begins with an overview of methods for computing and managing a variety of risk, then moves into a review of the economic foundation of modern risk management and the growing importance of model risk management. Market risk, portfolio credit risk, counterparty credit risk, liquidity risk, profitability analysis, stress testing, and others are dissected and examined, arming you with the strategies you need to construct a robust risk management system. The book takes readers through a journey from basic market risk analysis to major recent advances in all financial risk disciplines seen in the banking industry. The quantitative methodologies are developed with ample business case discussions and examples illustrating how they are used in practice. Chapters devoted to firmwide risk and stress testing cross reference the different methodologies developed for the specific risk areas and explain how they work together at firmwide level. Since risk regulations have driven a lot of the recent practices, the book also relates to the current global regulations in the financial risk areas. Risk management is one of the fastest growing segments of the banking industry, fueled by banks' fundamental intermediary role in the global economy and the industry's profit-driven increase in risk-seeking behavior. This book is the product of the authors' experience in developing and implementing risk analytics in banks around the globe, giving you a comprehensive, quantitative-oriented risk management guide specifically for the practitioner. Compute and manage market, credit, asset, and liability risk Perform macroeconomic stress testing and act on the results Get up to date on regulatory practices and model risk management Examine the structure and construction of financial risk systems Delve into funds transfer pricing, profitability analysis, and more Quantitative capability is increasing with lightning speed, both methodologically and technologically. Risk professionals must keep pace with the changes, and exploit every tool at their disposal. Financial Risk Management is the practitioner's guide to anticipating, mitigating, and preventing risk in the modern banking industry.
Sansone Eric B. Destruction of Hazardous Chemicals in the Laboratory Sansone Eric B. Destruction of Hazardous Chemicals in the Laboratory Новинка

Sansone Eric B. Destruction of Hazardous Chemicals in the Laboratory

10269.78 руб.
The book describes practical procedures for the destruction of hazardous chemicals and biological agents in the laboratory in which they are used. The book is a continuation and expansion of “Destruction of Hazardous Chemicals in the Laboratory.” It follows the same general approach as the first and second editions but includes a number of new chapters including one on using advanced oxidation techniques as a general means of degrading chemicals. All the monographs from the second edition are incorporated in this volume and are revised and extended as necessary. A number of new monographs describing procedures for the destruction of hazardous chemicals have also been added. The destruction of many pharmaceuticals is also described in this book. This subject has become of increasing importance with recent reports of the detection of pharmaceuticals in the water supply. Finally a new addition is the chapter “General Methods for the Destruction of Hazardous Chemicals in the Laboratory.” This chapter describes recent advanced oxidation methods that should be generally applicable to all organic compounds. The methods use commonly available laboratory equipment and reagents.
Terje Aven Uncertainty in Risk Assessment. The Representation and Treatment of Uncertainties by Probabilistic and Non-Probabilistic Methods Terje Aven Uncertainty in Risk Assessment. The Representation and Treatment of Uncertainties by Probabilistic and Non-Probabilistic Methods Новинка

Terje Aven Uncertainty in Risk Assessment. The Representation and Treatment of Uncertainties by Probabilistic and Non-Probabilistic Methods

7305 руб.
Explores methods for the representation and treatment of uncertainty in risk assessment In providing guidance for practical decision-making situations concerning high-consequence technologies (e.g., nuclear, oil and gas, transport, etc.), the theories and methods studied in Uncertainty in Risk Assessment have wide-ranging applications from engineering and medicine to environmental impacts and natural disasters, security, and financial risk management. The main focus, however, is on engineering applications. While requiring some fundamental background in risk assessment, as well as a basic knowledge of probability theory and statistics, Uncertainty in Risk Assessment can be read profitably by a broad audience of professionals in the field, including researchers and graduate students on courses within risk analysis, statistics, engineering, and the physical sciences. Uncertainty in Risk Assessment: Illustrates the need for seeing beyond probability to represent uncertainties in risk assessment contexts. Provides simple explanations (supported by straightforward numerical examples) of the meaning of different types of probabilities, including interval probabilities, and the fundamentals of possibility theory and evidence theory. Offers guidance on when to use probability and when to use an alternative representation of uncertainty. Presents and discusses methods for the representation and characterization of uncertainty in risk assessment. Uses examples to clearly illustrate ideas and concepts.
Terje Aven Risk Analysis Terje Aven Risk Analysis Новинка

Terje Aven Risk Analysis

5437.56 руб.
Risk Analysis, Second Edition Terje Aven, University of Stavanger, Norway A practical guide to the varied challenges presented in the ever-growing field of risk analysis. Risk Analysis presents an accessible and concise guide to performing risk analysis, in a wide variety of field, with minimal prior knowledge required. Forming an ideal companion volume to Aven's previous Wiley text Foundations of Risk Analysis, it provides clear recommendations and guidance in the planning, execution anduse of risk analysis. This new edition presents recent developments related to risk conceptualization, focusing on related issues on risk assessment and their application. New examples are also featured to clarify the reader's understanding in the application of risk analysis and the risk analysis process. Key features: Fully updated to include recent developments related to risk conceptualization and related issues on risk assessments and their applications. Emphasizes the decision making context of risk analysis rather than just computing probabilities Demonstrates how to carry out predictive risk analysis using a variety of case studies and examples. Written by an experienced expert in the field, in a style suitable for both industrial and academic audiences. This book is ideal for advanced undergraduates, graduates, analysts and researchers from statistics, engineering, finance, medicine and physical sciences. Managers facing decision making problems involving risk and uncertainty will also benefit from this book.
Kenett Ron S. Operational Risk Management. A Practical Approach to Intelligent Data Analysis Kenett Ron S. Operational Risk Management. A Practical Approach to Intelligent Data Analysis Новинка

Kenett Ron S. Operational Risk Management. A Practical Approach to Intelligent Data Analysis

9383.18 руб.
Models and methods for operational risks assessment and mitigation are gaining importance in financial institutions, healthcare organizations, industry, businesses and organisations in general. This book introduces modern Operational Risk Management and describes how various data sources of different types, both numeric and semantic sources such as text can be integrated and analyzed. The book also demonstrates how Operational Risk Management is synergetic to other risk management activities such as Financial Risk Management and Safety Management. Operational Risk Management: a practical approach to intelligent data analysis provides practical and tested methodologies for combining structured and unstructured, semantic-based data, and numeric data, in Operational Risk Management (OpR) data analysis. Key Features: The book is presented in four parts: 1) Introduction to OpR Management, 2) Data for OpR Management, 3) OpR Analytics and 4) OpR Applications and its Integration with other Disciplines. Explores integration of semantic, unstructured textual data, in Operational Risk Management. Provides novel techniques for combining qualitative and quantitative information to assess risks and design mitigation strategies. Presents a comprehensive treatment of «near-misses» data and incidents in Operational Risk Management. Looks at case studies in the financial and industrial sector. Discusses application of ontology engineering to model knowledge used in Operational Risk Management. Many real life examples are presented, mostly based on the MUSING project co-funded by the EU FP6 Information Society Technology Programme. It provides a unique multidisciplinary perspective on the important and evolving topic of Operational Risk Management. The book will be useful to operational risk practitioners, risk managers in banks, hospitals and industry looking for modern approaches to risk management that combine an analysis of structured and unstructured data. The book will also benefit academics interested in research in this field, looking for techniques developed in response to real world problems.
Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy Новинка

Oliver Muller Cancer Signaling, Enhanced Edition. From Molecular Biology to Targeted Therapy

5789.07 руб.
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive – and how they can be turned into potent weapons against it – is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
Laurence J. N. Cooper Immunotherapy in Translational Cancer Research Laurence J. N. Cooper Immunotherapy in Translational Cancer Research Новинка

Laurence J. N. Cooper Immunotherapy in Translational Cancer Research

14776.04 руб.
A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.
Allan Malz M. Financial Risk Management. Models, History, and Institutions Allan Malz M. Financial Risk Management. Models, History, and Institutions Новинка

Allan Malz M. Financial Risk Management. Models, History, and Institutions

5849.09 руб.
Financial risk has become a focus of financial and nonfinancial firms, individuals, and policy makers. But the study of risk remains a relatively new discipline in finance and continues to be refined. The financial market crisis that began in 2007 has highlighted the challenges of managing financial risk. Now, in Financial Risk Management, author Allan Malz addresses the essential issues surrounding this discipline, sharing his extensive career experiences as a risk researcher, risk manager, and central banker. The book includes standard risk measurement models as well as alternative models that address options, structured credit risks, and the real-world complexities or risk modeling, and provides the institutional and historical background on financial innovation, liquidity, leverage, and financial crises that is crucial to practitioners and students of finance for understanding the world today. Financial Risk Management is equally suitable for firm risk managers, economists, and policy makers seeking grounding in the subject. This timely guide skillfully surveys the landscape of financial risk and the financial developments of recent decades that culminated in the crisis. The book provides a comprehensive overview of the different types of financial risk we face, as well as the techniques used to measure and manage them. Topics covered include: Market risk, from Value-at-Risk (VaR) to risk models for options Credit risk, from portfolio credit risk to structured credit products Model risk and validation Risk capital and stress testing Liquidity risk, leverage, systemic risk, and the forms they take Financial crises, historical and current, their causes and characteristics Financial regulation and its evolution in the wake of the global crisis And much more Combining the more model-oriented approach of risk management-as it has evolved over the past two decades-with an economist's approach to the same issues, Financial Risk Management is the essential guide to the subject for today's complex world.
Prokar Dasgupta ABC of Prostate Cancer Prokar Dasgupta ABC of Prostate Cancer Новинка

Prokar Dasgupta ABC of Prostate Cancer

2963.19 руб.
Prostate cancer is the most common cancer in men in the UK and US and the second most common worldwide. The ABC of Prostate Cancer provides fully illustrated guidance on the treatment and management of prostate cancer. It covers the biology, anatomy, and pathology of prostate cancer, screening, and active surveillance and monitoring. It presents an assessment of treatment options including prostatectomy, bracytherapy, chemotherapy and immunotherapy, along with modern diagnostic tests and an overview of new approaches to prostate cancer. With an international author team, the ABC of Prostate Cancer is ideal for general practitioners, family physicians, specialist nurses, junior doctors, medical students and others working with prostate cancer patients and their families.
Abdelhalim Boussabaine Risk Pricing Strategies for Public-Private Partnership Projects Abdelhalim Boussabaine Risk Pricing Strategies for Public-Private Partnership Projects Новинка

Abdelhalim Boussabaine Risk Pricing Strategies for Public-Private Partnership Projects

8176.93 руб.
The complexity of public-private partnership project procurement requires an effective process for pricing, managing and appropriate allocation of risks. The level at which risk is priced and the magnitude of risks transferred to the private sector will have a significant impact on the cost of the PPP deals as well as on the value for money analysis and on the section of the optimum investment options. The construction industry tends to concentrate on the effectiveness of risk management strategies and to some extent ignores the price of risk and its impact on whole life cost of building assets. There is a pressing need for a universal framework for the determination of fair value of risks throughout the PPP procurement processes. Risk Pricing Strategies for Public-Private Partnership Projects addresses the issues of risk pricing and demonstrates the use of a coherent strategy to arrive at a fair risk price. The focus of the book is on providing risk pricing strategies to maximise return on risk retention and allocation in the procurement of PPP projects. With its up-to-date coverage of the latest developments in risk pricing and comprehensive treatment of the methodologies involved in designing and building risk pricing strategies, the book offers a simple model for pricing risks. The book follows a thematic structure: PPP processes map; Risk, uncertainty and bias; Risk pricing management strategies; Risk pricing measurement and modelling; Risk pricing at each of the project life cycle stages – and deals with all the important risk pricing issues, using relevant real-world situations through case study examples. It explains how the theory and strategies of risk pricing can be successfully applied to real PPP projects and reflects the broad understanding required by today’s project risk analysts, in their new and important role in PPP contract management.
Norman Sartorius Depression and Cancer Norman Sartorius Depression and Cancer Новинка

Norman Sartorius Depression and Cancer

4413.21 руб.
Recently, there has been a growing awareness of the multiple interrelationships between depression and cancer. Depression and Cancer is devoted to the interaction between these disorders. The book examines various aspects of this comorbidity and describes how the negative consequences of depression in cancer could be avoided or ameliorated, given that effective depression treatments for cancer patients are available. Renowned psychiatrists and oncologists summarize the latest evidence on the epidemiology, pathogenesis, screening and recognition, and cultural and public health implications of depression in persons with cancer, among other topics.
Talbot John Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice Talbot John Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice Новинка

Talbot John Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice

29479.43 руб.
The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines. This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia. Praise for previous editions "This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” – from a review in E-STREAMS «…a key text in the area of pharmacovigilance…extensively referenced and well-written…a valuable resource…» – from a review in The Pharmaceutical Journal
Terje Aven Foundations of Risk Analysis Terje Aven Foundations of Risk Analysis Новинка

Terje Aven Foundations of Risk Analysis

6353.96 руб.
Foundations of Risk Analysis presents the issues core to risk analysis – understanding what risk means, expressing risk, building risk models, addressing uncertainty, and applying probability models to real problems. The author provides the readers with the knowledge and basic thinking they require to successfully manage risk and uncertainty to support decision making. This updated edition reflects recent developments on risk and uncertainty concepts, representations and treatment. New material in Foundations of Risk Analysis includes: An up to date presentation of how to understand, define and describe risk based on research carried out in recent years. A new definition of the concept of vulnerability consistent with the understanding of risk. Reflections on the need for seeing beyond probabilities to measure/describe uncertainties. A presentation and discussion of a method for assessing the importance of assumptions (uncertainty factors) in the background knowledge that the subjective probabilities are based on A brief introduction to approaches that produce interval (imprecise) probabilities instead of exact probabilities. In addition the new version provides a number of other improvements, for example, concerning the use of cost-benefit analyses and the As Low As Reasonably Practicable (ALARP) principle. Foundations of Risk Analysis provides a framework for understanding, conducting and using risk analysis suitable for advanced undergraduates, graduates, analysts and researchers from statistics, engineering, finance, medicine and the physical sciences, as well as for managers facing decision making problems involving risk and uncertainty.
Alessandro Gandini Chemicals and Fuels from Bio-Based Building Blocks Alessandro Gandini Chemicals and Fuels from Bio-Based Building Blocks Новинка

Alessandro Gandini Chemicals and Fuels from Bio-Based Building Blocks

23518.11 руб.
An up-to-date and two volume overview of recent developments in the field of chemocatalytic and enzymatic processes for the transformation of renewable material into essential chemicals and fuels. Experts from both academia and industry discuss catalytic processes currently under development as well as those already in commercial use for the production of bio-fuels and bio-based commodity chemicals. As such, they cover drop-in commodity chemicals and fuels, as well as bio-based monomers and polymers, such as acrylic acid, glycols, polyesters and polyolefins. In addition, they also describe reactions applied to waste and biomass valorization and integrated biorefining strategies. With its comprehensive coverage of the topic, this is an indispensable reference for chemists working in the field of catalysis, industrial chemistry, sustainable chemistry, and polymer synthesis.
Global Association of Risk Professionals Foundations of Energy Risk Management. An Overview of the Energy Sector and Its Physical and Financial Markets Global Association of Risk Professionals Foundations of Energy Risk Management. An Overview of the Energy Sector and Its Physical and Financial Markets Новинка

Global Association of Risk Professionals Foundations of Energy Risk Management. An Overview of the Energy Sector and Its Physical and Financial Markets

7018.91 руб.
GARP's Fundamentals of Energy Risk Management introduces investors to the basic components and some of the basic terminology used in the energy industry. It covers the commodity cycle, energy use and sources, and various risk types, various energy products and the markets where energy is traded. It also introduces certain risk management fundamentals and real option thinking. The book is GARP's required text used by risk professionals looking to obtain their Certificate in Energy Risk Management.
Matt Sekerke Bayesian Risk Management. A Guide to Model Risk and Sequential Learning in Financial Markets Matt Sekerke Bayesian Risk Management. A Guide to Model Risk and Sequential Learning in Financial Markets Новинка

Matt Sekerke Bayesian Risk Management. A Guide to Model Risk and Sequential Learning in Financial Markets

5849.09 руб.
A risk measurement and management framework that takes model risk seriously Most financial risk models assume the future will look like the past, but effective risk management depends on identifying fundamental changes in the marketplace as they occur. Bayesian Risk Management details a more flexible approach to risk management, and provides tools to measure financial risk in a dynamic market environment. This book opens discussion about uncertainty in model parameters, model specifications, and model-driven forecasts in a way that standard statistical risk measurement does not. And unlike current machine learning-based methods, the framework presented here allows you to measure risk in a fully-Bayesian setting without losing the structure afforded by parametric risk and asset-pricing models. Recognize the assumptions embodied in classical statistics Quantify model risk along multiple dimensions without backtesting Model time series without assuming stationarity Estimate state-space time series models online with simulation methods Uncover uncertainty in workhorse risk and asset-pricing models Embed Bayesian thinking about risk within a complex organization Ignoring uncertainty in risk modeling creates an illusion of mastery and fosters erroneous decision-making. Firms who ignore the many dimensions of model risk measure too little risk, and end up taking on too much. Bayesian Risk Management provides a roadmap to better risk management through more circumspect measurement, with comprehensive treatment of model uncertainty.
Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors Новинка

Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors

11212.9 руб.
Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.
Mario Lacouture E. Dermatologic Principles and Practice in Oncology. Conditions of the Skin, Hair, and Nails in Cancer Patients Mario Lacouture E. Dermatologic Principles and Practice in Oncology. Conditions of the Skin, Hair, and Nails in Cancer Patients Новинка

Mario Lacouture E. Dermatologic Principles and Practice in Oncology. Conditions of the Skin, Hair, and Nails in Cancer Patients

13443.06 руб.
The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patients According to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with these events, which pose serious quality-of-life issues with so many patients, and will become more prevalent as survival rates improve, thanks in part to new cancer treatments and drug regimens. Concentrating on a topic that has only been briefly touched upon by other texts, this book offers a focused perspective on the clinical presentation, underlying pathophysiologic mechanisms, and management of skin, hair, and nail conditions for oncologists, dermatologists, and allied practitioners. Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients: • Covers in detail the dermatologic adverse events of oncologic therapies, clinical presentations, and treatment recommendations • Enables dermatologists and other practitioners to significantly improve the care of patients with cancer • Addresses the dermatologic adverse events of cancer therapies used globally, of which a large number are found in developing countries • Emphasizes prophylactic measures – based on treatments used and type of cancer – to prevent the appearance of adverse events • Provides built-in discussions on patient education for practical counseling during therapies • Offers rapid-reference sections on topical dermatology drugs The first book to present dermatologic conditions in cancer patients and survivors in a uniform and in-depth manner, Dermatologic Principles and Practice in Oncology is ideal for oncologists, oncology nurses, and dermatologists who wish to take better care of those with adverse skin, hair, and nail conditions.
Kagan Eugene Probabilistic Search for Tracking Targets. Theory and Modern Applications Kagan Eugene Probabilistic Search for Tracking Targets. Theory and Modern Applications Новинка

Kagan Eugene Probabilistic Search for Tracking Targets. Theory and Modern Applications

8348.81 руб.
Presents a probabilistic and information-theoretic framework for a search for static or moving targets in discrete time and space. Probabilistic Search for Tracking Targets uses an information-theoretic scheme to present a unified approach for known search methods to allow the development of new algorithms of search. The book addresses search methods under different constraints and assumptions, such as search uncertainty under incomplete information, probabilistic search scheme, observation errors, group testing, search games, distribution of search efforts, single and multiple targets and search agents, as well as online or offline search schemes. The proposed approach is associated with path planning techniques, optimal search algorithms, Markov decision models, decision trees, stochastic local search, artificial intelligence and heuristic information-seeking methods. Furthermore, this book presents novel methods of search for static and moving targets along with practical algorithms of partitioning and search and screening. Probabilistic Search for Tracking Targets includes complete material for undergraduate and graduate courses in modern applications of probabilistic search, decision-making and group testing, and provides several directions for further research in the search theory. The authors: Provide a generalized information-theoretic approach to the problem of real-time search for both static and moving targets over a discrete space. Present a theoretical framework, which covers known information-theoretic algorithms of search, and forms a basis for development and analysis of different algorithms of search over probabilistic space. Use numerous examples of group testing, search and path planning algorithms to illustrate direct implementation in the form of running routines. Consider a relation of the suggested approach with known search theories and methods such as search and screening theory, search games, Markov decision process models of search, data mining methods, coding theory and decision trees. Discuss relevant search applications, such as quality-control search for nonconforming units in a batch or a military search for a hidden target. Provide an accompanying website featuring the algorithms discussed throughout the book, along with practical implementations procedures.
Jack Roth A. Lung Cancer Jack Roth A. Lung Cancer Новинка

Jack Roth A. Lung Cancer

13456.58 руб.
The best and most concise single source for state-of-the-art diagnosis and treatment of lung cancer –newly revised, updated, and expanded. Lung cancer has long been the number-one cause of death from cancer every year and the third most frequently diagnosed after breast and prostate cancers. In 2010, about 15% of all cancer diagnoses and 30% of all cancer deaths were due to lung cancer. Needless to say, there is a great need for more rapid advancements in diagnosis and treatment of this devastating disease. Here is the comprehensively revised, updated, and expanded edition of the well-established, evidence-based reference book that deals with the most recent advances in lung cancer prevention, screening, diagnosis, research, and treatment for the clinician. Edited and authored by leading authorities in the field, this Fourth Edition of the highly regarded Lung Cancer is better than ever –featuring nine new chapters along with seven re-formatted ones that are nearly brand new in content and approach. It covers Smoking Prevention and Cessation; Molecular Profiling; Somatic Genome Alterations in Human Lung Cancers; Management of Multi-Focal Bronchioloalveolar Carcinoma (BAC); Primary Tracheal Tumors; Predictive Tumor Biomarkers for EGFR Inhibitors; Non-Small Cell and Small-Cell Lung Carcinoma; and more. This Fourth Edition of Lung Cancer: Provides the very latest research in the identification of biomarkers to predict a high risk for developing lung cancer – vital for implementing screening, diagnosis, and prevention strategies Presents the newest lung cancer staging system, as well as updated and cutting-edge surgical and radiation therapy techniques that make local tumor control more effective and less invasive while sparing normal tissues Discusses combined modality therapy and new chemotherapeutic agents which are yielding higher response rates and improved survival when used in the adjuvant setting or concurrent with highly sophisticated radiation or proton treatment Offers novel and emergent approaches to preventative, diagnostic, and therapeutic modalities with an emphasis on the best evidence available from the latest studies and clinical trials With almost half of the revised and updated content being brand new, Lung Cancer, Fourth Edition, is an important and vital resource for all medical professionals and students involved in the care and treatment of those struck with this catastrophic illness.
Thomas Meyer Mastering Illiquidity. Risk management for portfolios of limited partnership funds Thomas Meyer Mastering Illiquidity. Risk management for portfolios of limited partnership funds Новинка

Thomas Meyer Mastering Illiquidity. Risk management for portfolios of limited partnership funds

6156.94 руб.
Arms investors with powerful new tools for measuring and managing the risks associated with the various illiquid asset classes With risk-free interest rates and risk premiums at record lows, many investors are turning to illiquid assets, such as real estate, private equity, infrastructure and timber, in search of superior returns and greater portfolio diversity. But as many analysts, investors and wealth managers are discovering, such investments bring with them a unique set of risks that cannot be measured by standard asset allocation models. Written by a dream team of globally renowned experts in the field, this book provides a clear, accessible overview of illiquid fund investments, focusing on what the main risks of these asset classes are and how to measure those risks in today's regulatory environment. Provides solutions for institutional investors in need of guidance in today's regulatory environment Offers detailed descriptions of risk measurement in illiquid asset classes, illustrated with real life case studies Helps you to develop reliable risk management tools while complying with the regulations designed to contain the individual and systemic risks arising from illiquid investments Features real-life case studies that capture an array of risk management scenarios you are likely to encounter
Daniel Norwood L. Leachables and Extractables Handbook. Safety Evaluation, Qualification, and Best Practices Applied to Inhalation Drug Products Daniel Norwood L. Leachables and Extractables Handbook. Safety Evaluation, Qualification, and Best Practices Applied to Inhalation Drug Products Новинка

Daniel Norwood L. Leachables and Extractables Handbook. Safety Evaluation, Qualification, and Best Practices Applied to Inhalation Drug Products

10492.7 руб.
A practical and science-based approach for addressing toxicological concerns related to leachables and extractables associated with inhalation drug products Packaging and device components of Orally Inhaled and Nasal Drug Products (OINDP)—such as metered dose inhalers, dry powder inhalers, and nasal sprays—pose potential safety risks from leachables and extractables, chemicals that can be released or migrate from these components into the drug product. Addressing the concepts, background, historical use, and development of safety thresholds and their utility for qualifying leachables and extractables in OINDP, the Leachables and Extractables Handbook takes a practical approach to familiarize readers with the recent recommendations for safety and risk assessment established through a joint effort of scientists from the FDA, academia, and industry. Coverage includes best practices for the chemical evaluation and management of leachables and extractables throughout the pharmaceutical product life cycle, as well as: Guidance for pharmaceutical professionals to qualify and risk-assess container closure system leachables and extractables in drug products Principles for defining toxicological safety thresholds that are applicable to OINDP and potentially applicable to other drug products Regulatory perspectives, along with an appendix of key terms and definitions, case studies, and sample protocols Analytical chemists, packaging and device engineers, formulation development scientists, component suppliers, regulatory affairs specialists, and toxicologists will all benefit from the wealth of information offered in this important text.
Clifford Rossi A Risk Professional's Survival Guide. Applied Best Practices in Risk Management Clifford Rossi A Risk Professional's Survival Guide. Applied Best Practices in Risk Management Новинка

Clifford Rossi A Risk Professional's Survival Guide. Applied Best Practices in Risk Management

5849.09 руб.
Balanced, practical risk management for post – financial crisis institutions Fundamentals of Risk Management fills a critical gap left by existing risk management texts. Instead of focusing only on quantitative risk analysis or only on institutional risk management, this book takes a comprehensive approach. The disasters of the recent financial crisis taught us that managing risk is both an art and a science, and it is critical for practitioners to understand how individual risks are integrated at the enterprise level. This book is the only resource of its kind to introduce all of the key risk management concepts in a cohesive case study spanning each chapter. A hypothetical bank drawn from elements of several real world institutions serves as a backdrop for topics from credit risk and operational risk to understanding big-picture risk exposure. You will be able to see exactly how each rigorous concept is applied in actual risk management contexts. Fundamentals of Risk Management includes: Supplemental Excel-based Visual Basic (VBA) modules, so you can interact directly with risk models Clear explanations of the importance of risk management in preventing financial disasters Real world examples and lessons learned from past crises Risk policies, infrastructure, and activities that balance limited quantitative models This book provides the element of hands-on application necessary to put enterprise risk management into effective practice. The very best risk managers rely on a balanced approach that leverages every aspect of financial operations for an integrative risk management strategy. With Fundamentals of Risk Management, you can identify and control risk at an expert level.
R. Rajagopal Sustainable Value Creation in the Fine and Speciality Chemicals Industry R. Rajagopal Sustainable Value Creation in the Fine and Speciality Chemicals Industry Новинка

R. Rajagopal Sustainable Value Creation in the Fine and Speciality Chemicals Industry

10492.7 руб.
The global fine and speciality chemicals industry is a vital segment within the chemical value chain, catering to a multitude of societal and industrial needs. Regulatory, sustainability and consumer forces have been constantly shaping the business fundamentals of this industry. Developing value creation strategies, which embed economic, environmental and social sustainability components, will need a comprehensive assessment of business, scientific and technological challenges facing the industry. Sustainable Value Creation in the Fine and Speciality Chemicals Industry assesses sustainable value creation options against the backdrop of global mega trends that are defi ning the present and future course of the industry. It discusses innovative strategies in feedstocks, R&D, technology, manufacturing, resource management and the supply chain as well as the significance of the bio-based chemical economy in enabling sustainable value creation in the fine and speciality chemicals industry. Topics covered include: • Transformation in the fine and speciality chemicals business • Sustainable management: evolution, transitions and tools • Research and technology directions • Resource optimization strategies • Bio-based chemicals, specialities and polymers • Sustainable practices in the fine and speciality chemicals industry • Sustainable value creation strategies Sustainable Value Creation in the Fine and Speciality Chemicals Industry presents a comprehensive overview of strategic options for sustainability management in the global fine and speciality chemicals industry. It will be a valuable resource for chemists and chemical engineers involved in the design and development of economically, environmentally and socially sustainable practices for the future.
John Fraser Enterprise Risk Management. Today's Leading Research and Best Practices for Tomorrow's Executives John Fraser Enterprise Risk Management. Today's Leading Research and Best Practices for Tomorrow's Executives Новинка

John Fraser Enterprise Risk Management. Today's Leading Research and Best Practices for Tomorrow's Executives

6156.94 руб.
Essential insights on the various aspects of enterprise risk management If you want to understand enterprise risk management from some of the leading academics and practitioners of this exciting new methodology, Enterprise Risk Management is the book for you. Through in-depth insights into what practitioners of this evolving business practice are actually doing as well as anticipating what needs to be taught on the topic, John Fraser and Betty Simkins have sought out the leading experts in this field to clearly explain what enterprise risk management is and how you can teach, learn, and implement these leading practices within the context of your business activities. In this book, the authors take a broad view of ERM, or what is called a holistic approach to ERM. Enterprise Risk Management introduces you to the wide range of concepts and techniques for managing risk in a holistic way that correctly identifies risks and prioritizes the appropriate responses. This invaluable guide offers a broad overview of the different types of techniques: the role of the board, risk tolerances, risk profiles, risk workshops, and allocation of resources, while focusing on the principles that determine business success. This comprehensive resource also provides a thorough introduction to enterprise risk management as it relates to credit, market, and operational risk, as well as the evolving requirements of the rating agencies and their importance to the overall risk management in a corporate setting. Filled with helpful tables and charts, Enterprise Risk Management offers a wealth of knowledge on the drivers, the techniques, the benefits, as well as the pitfalls to avoid, in successfully implementing enterprise risk management. Discusses the history of risk management and more recently developed enterprise risk management practices and how you can prudently implement these techniques within the context of your underlying business activities Provides coverage of topics such as the role of the chief risk officer, the use of anonymous voting technology, and risk indicators and their role in risk management Explores the culture and practices of enterprise risk management without getting bogged down by the mathematics surrounding the more conventional approaches to financial risk management This informative guide will help you unlock the incredible potential of enterprise risk management, which has been described as a proxy for good management.
Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications and Therapeutics Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications and Therapeutics Новинка

Tarik Regad Principles of Stem Cell Biology and Cancer. Future Applications and Therapeutics

10851.08 руб.
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.
McQueen Anne Perspectives on Cancer Care McQueen Anne Perspectives on Cancer Care Новинка

McQueen Anne Perspectives on Cancer Care

3989.08 руб.
Perspectives on Cancer Care is a unique collection of insights from contributors, based on their specific expertise and experience. It provides a range of perspectives on cancer care to inspire readers and encourage high-quality care through an enhanced understanding of patients' needs and carers' skills. The book presents a series of chapters highlighting different circumstances and approaches to the complex reality of cancer care. In each chapter the author presents their own picture of their experience of the individual's needs and the care required to address these needs, illustrating the particular sensitivity, trust, empathy and support required in the care of patients with cancer and their families. The holistic approach to total care is a prominent feature in cancer care and this is illustrated throughout the various chapters. This collection of perspectives on cancer care: highlights particular issues in the field encourages best practice draws on the expertise of specialist practitioners in the field of cancer care features a holistic approach to cancer care, illustrated through scenarios
Christian Wittekind TNM Atlas Christian Wittekind TNM Atlas Новинка

Christian Wittekind TNM Atlas

8249.7 руб.
The complete, authoritative TNM cancer classification and staging system—now illustrated with new, full-colour figures for fast, effective, anatomical referencing Referring to “Tumour,” “Node,” and “Metastasis,” the TNM system is the most widely used means for classifying and staging the extent of cancer spread. Published in affiliation with the Union for International Cancer Control (UICC), TNM Atlas, Sixth Edition presents the illustrated version of the TNM Classification of Malignant Tumours, Seventh Edition, promoting the uniform application of the TNM classification in cancer practice. Utilizing beautiful, full-colour medical artwork—illustrating the T and N categories in clear, easily understood graphics—this book aides in the practical application of the TNM classification system. It enables all disciplines involved in cancer classification, staging, and treatment to reach a more standardized understanding and documentation of the anatomical spread of tumours, and further enhances the dissemination and use of the TNM classification. The TNM Atlas, Sixth Edition: • Is based upon the very latest TNM Classification data available in TNM Classification of Malignant Tumours, Seventh Edition • Features over 500 full-colour figures that clearly illustrate and highlight anatomical sites of cancer involvement • Makes TNM classification even more clinically applicable in the day-to-day environment • Is an extremely useful tool for clinical reference, teaching, discussion, and patient education Based in Geneva, the UICC is one of the most widely affiliated cancer organisations in the world, with its core mission being cancer classification and control. Its TNM Atlas, Sixth Edition is a valuable reference for all medical, surgical, and radiation oncologists, anatomical and surgical pathologists, cancer registrars, oncology nurses and physician extenders, international cancer care centres, and governmental and NGOs dedicated to cancer control. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play.
Maurie Markman Targeted Therapy in Translational Cancer Research Maurie Markman Targeted Therapy in Translational Cancer Research Новинка

Maurie Markman Targeted Therapy in Translational Cancer Research

10851.08 руб.
Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities
Hamid Mollah Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing Hamid Mollah Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing Новинка

Hamid Mollah Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing

9913.93 руб.
Sets forth tested and proven risk management practices in drug manufacturing Risk management is essential for safe and efficient pharmaceutical and biopharmaceutical manufacturing, control, and distribution. With this book as their guide, readers involved in all facets of drug manufacturing have a single, expertly written, and organized resource to guide them through all facets of risk management and analysis. It sets forth a solid foundation in risk management concepts and then explains how these concepts are applied to drug manufacturing. Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing features contributions from leading international experts in risk management and drug manufacturing. These contributions reflect the latest research, practices, and industry standards as well as the authors' firsthand experience. Readers can turn to the book for: Basic foundation of risk management principles, practices, and applications Tested and proven tools and methods for managing risk in pharmaceutical and biopharmaceutical product manufacturing processes Recent FDA guidelines, EU regulations, and international standards governing the application of risk management to drug manufacturing Case studies and detailed examples demonstrating the use and results of applying risk management principles to drug product manufacturing Bibliography and extensive references leading to the literature and helpful resources in the field With its unique focus on the application of risk management to biopharmaceutical and pharmaceutical manufacturing, this book is an essential resource for pharmaceutical and process engineers as well as safety and compliance professionals involved in drug manufacturing.
Logan Caroline Self-Harm and Violence. Towards Best Practice in Managing Risk in Mental Health Services Logan Caroline Self-Harm and Violence. Towards Best Practice in Managing Risk in Mental Health Services Новинка

Logan Caroline Self-Harm and Violence. Towards Best Practice in Managing Risk in Mental Health Services

9010.07 руб.
Self-Harm and Violence: Towards Best Practice in Managing Risk in Mental Health Services presents the first exploration of the most effective clinical practice techniques relating to the management of risk in mental health care settings. Based on the Department of Health’s Best Practice in Managing Risk guidance document, which was developed over a 12-month period in consultation with a national expert advisory group Features contributions from many members of the group that drew up the Best Practice document – all leading theoreticians and practitioners in their particular fields – and embeds the principles laid out in the guidelines in real world practice Reveals how contemporary risk management is a multidisciplinary and collaborative enterprise in which practitioners from different professions need to engage with each other in order to achieve success

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A global banking risk management guide geared toward the practitioner Financial Risk Management presents an in-depth look at banking risk on a global scale, including comprehensive examination of the U.S. Comprehensive Capital Analysis and Review, and the European Banking Authority stress tests. Written by the leaders of global banking risk products and management at SAS, this book provides the most up-to-date information and expert insight into real risk management. The discussion begins with an overview of methods for computing and managing a variety of risk, then moves into a review of the economic foundation of modern risk management and the growing importance of model risk management. Market risk, portfolio credit risk, counterparty credit risk, liquidity risk, profitability analysis, stress testing, and others are dissected and examined, arming you with the strategies you need to construct a robust risk management system. The book takes readers through a journey from basic market risk analysis to major recent advances in all financial risk disciplines seen in the banking industry. The quantitative methodologies are developed with ample business case discussions and examples illustrating how they are used in practice. Chapters devoted to firmwide risk and stress testing cross reference the different methodologies developed for the specific risk areas and explain how they work together at firmwide level. Since risk regulations have driven a lot of the recent practices, the book also relates to the current global regulations in the financial risk areas. Risk management is one of the fastest growing segments of the banking industry, fueled by banks' fundamental intermediary role in the global economy and the industry's profit-driven increase in risk-seeking behavior. This book is the product of the authors' experience in developing and implementing risk analytics in banks around the globe, giving you a comprehensive, quantitative-oriented risk management guide specifically for the practitioner. Compute and manage market, credit, asset, and liability risk Perform macroeconomic stress testing and act on the results Get up to date on regulatory practices and model risk management Examine the structure and construction of financial risk systems Delve into funds transfer pricing, profitability analysis, and more Quantitative capability is increasing with lightning speed, both methodologically and technologically. Risk professionals must keep pace with the changes, and exploit every tool at their disposal. Financial Risk Management is the practitioner's guide to anticipating, mitigating, and preventing risk in the modern banking industry.
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