invitro anticancer activity of novel thiadiazole derivatives



Vijay Kumar Singh, U. K. Sharma, Shobhit Singh Synthesis and Antimicrobial Activity of Benzotriazole Derivatives Vijay Kumar Singh, U. K. Sharma, Shobhit Singh Synthesis and Antimicrobial Activity of Benzotriazole Derivatives Новинка

Vijay Kumar Singh, U. K. Sharma, Shobhit Singh Synthesis and Antimicrobial Activity of Benzotriazole Derivatives

8789 руб.
The practice of medicinal chemistry is devoted to the discovery and development of new chemical agents for treating disease. Most of the activity in this discipline is directed to the search of new natural or synthetic organic compounds. The present work emphasizes the synthesis of novel derivatives of benzotriazolothiadiazolyl thiazolidinones having three nuclei in combination with each other (viz. Benzotriazole, Thiadiazole and Thiazolidinone) along with their antimicrobial activity. The structure of synthesized compounds has been established on the basis of their physico-chemical properties and spectral data (I.R. and N.M.R. spectroscopy).
Kharb Rajeev Novel Heterocyclic Scaffolds having Anticancer Potential Kharb Rajeev Novel Heterocyclic Scaffolds having Anticancer Potential Новинка

Kharb Rajeev Novel Heterocyclic Scaffolds having Anticancer Potential

5214 руб.
Cancer is a serious global health concern as it is a deadly disease being responsible for about 13% of total death tolls globally and at present, cancer is the second leading cause of death in the world after cardiovascular diseases as reported by WHO. Despite advances in cancer research, the overall survival of cancer patients remains low. Inherent and acquired resistance to treatment and the dose-limiting toxicity caused by the narrow therapeutic window of many anticancer drugs are recognized as obstacles for effective treatment of cancer. As per recent literature, it has been found that novel heterocyclic derivatives such as imidazole, triazole, thiazole, benzothiophene, coumarin, furan and isoxazole derivatives as anticancer drugs are lesser toxic, experience lesser resistance from cancerous cells and capable of targeting tumor DNA more specifically as compared to currently used anticancer drugs. Therefore, this communication is an endeavor to update the recent advances and development in the field of cancer research to develop novel anticancer agents for future having better safety and site specific receptors binding for effective treatment of cancer as a deadly disease.
Bariwal Jitender, Kaur Gurneet, Kaur Rupinder New .1,4.Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs Bariwal Jitender, Kaur Gurneet, Kaur Rupinder New .1,4.Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs Новинка

Bariwal Jitender, Kaur Gurneet, Kaur Rupinder New .1,4.Dihydropyridines for P-gp Mediated Efflux of Anticancer Drugs

5902 руб.
Cancer is a leading cause of death these days which require chemotherapeutic drugs for treatment. Although various chemotherapeutic agents have been developed, still there is no successful treatment against multidrug resistance acquired by the cancer cells due to high P-gp expression in the cell walls. In the effort to synthesize new compounds that overcome multidrug resistance, we have synthesized a novel series of N-unsubstituted and N-substituted [1,4]-DHPs and evaluated these derivatives for P-gp inhibitory activity using Rhodamine B as P-gp substrate. From the in vitro assay, it has been found that N-substituted [1,4]-DHPs exhibits improved activity then N-unsubstituted compounds. The aliphatic substitution at 1st position of unsymmetrical [1,4]-DHPs resulted in good fluorescence uptake.
Rathavi Anil Study of s-triazine derivatives Rathavi Anil Study of s-triazine derivatives Новинка

Rathavi Anil Study of s-triazine derivatives

5352 руб.
Different types of 2,4,6-Trichloro-[1,3,5]triazine derivatives were synthesized by using morpholine and different types of amines. The synthesized structures of these compounds were confirmed by Mass, IR and 1H NMR spectral analysis. The newly synthesized compounds were also evaluated for antimicrobial activity against variety of bacterial strains and some of these compounds have shown good antimicrobial activities.
Vyas Sandip P. Therapeutic Study of Pyrimidine Derivatives Vyas Sandip P. Therapeutic Study of Pyrimidine Derivatives Новинка

Vyas Sandip P. Therapeutic Study of Pyrimidine Derivatives

8789 руб.
Pyrimidine derivatives possess good Therapeutic and Biological activity. This book describes literature survey and synthesis methods of some important Pyrimidine derivatives. All the new compounds characterized by C,H,N Elemental Analysis, FT-IR, 1H NMR and Mass Spectra. This book is very much useful for post gradute and research scholar in Chemistry, Pharmacy and Microbiology who are familiar with syntheis of Heterocyclic derivatives and their biological evaluation.
Asirvatham Sahaya Synthesis, Docking and QSAR of Isoxazole derivatives Asirvatham Sahaya Synthesis, Docking and QSAR of Isoxazole derivatives Новинка

Asirvatham Sahaya Synthesis, Docking and QSAR of Isoxazole derivatives

9277 руб.
A series of newer 3-(4'-methoxyphenyl)-5-substituted phenylisoxazoles derivatives have been synthesized by reacting hydroxylamine hydrochloride with chalcone. The chalcones were formed by reacting different aromatic aldehydes with 4-methoxyacetophenone in presence of aqueos KOH. The acute toxicity study was carried on all the synthesized compounds and they were screened for their anti-inflammatory activity by carrageenan induced paw edema method. Anti-inflammatory studies showed statistically significant activity when compared to control indomethacin. The two most potent compounds giving good anti-inflammatory activity were further evaluated for their anti-ulcer activity. The compounds were subjected to docking and quantitative structure activity relationships (QSAR) studies.
Priyal Jain, Nilesh Jain, Vaibhav Jain QSAR Based Design . Synthesis Priyal Jain, Nilesh Jain, Vaibhav Jain QSAR Based Design . Synthesis Новинка

Priyal Jain, Nilesh Jain, Vaibhav Jain QSAR Based Design . Synthesis

8652 руб.
We carried out a QSAR study on benzotriazine derivatives & studied 28 potent GABAA receptor ligands; derivatives of benzotriazines, using a combination of various physicochemical, steric, electronic and thermodynamic descriptors to determine the quantitative correlation between binding affinity and structural features with potent anticonvulsant activity. Correlation between these properties and anticonvulsant activity was used to synthesize compounds possessing potent anticonvulsant activity. Most of the compounds showed an ability to inhibit the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions. Compound 1A, i.e. 2-(4-Chloro-phenyl)-5-nitro-1H-benzimidazole exhibited maximum activity.
Robert Kolb W. Financial Derivatives. Pricing and Risk Management Robert Kolb W. Financial Derivatives. Pricing and Risk Management Новинка

Robert Kolb W. Financial Derivatives. Pricing and Risk Management

6269.63 руб.
Essential insights on the various aspects of financial derivatives If you want to understand derivatives without getting bogged down by the mathematics surrounding their pricing and valuation, Financial Derivatives is the book for you. Through in-depth insights gleaned from years of financial experience, Robert Kolb and James Overdahl clearly explain what derivatives are and how you can prudently use them within the context of your underlying business activities. Financial Derivatives introduces you to the wide range of markets for financial derivatives. This invaluable guide offers a broad overview of the different types of derivatives-futures, options, swaps, and structured products-while focusing on the principles that determine market prices. This comprehensive resource also provides a thorough introduction to financial derivatives and their importance to risk management in a corporate setting. Filled with helpful tables and charts, Financial Derivatives offers a wealth of knowledge on futures, options, swaps, financial engineering, and structured products. Discusses what derivatives are and how you can prudently implement them within the context of your underlying business activities Provides thorough coverage of financial derivatives and their role in risk management Explores financial derivatives without getting bogged down by the mathematics surrounding their pricing and valuation This informative guide will help you unlock the incredible potential of financial derivatives.
Krunalkumar R. Mehariya, Bhagwati K. Gauni Mehariya Synthesis, Characterization, and Single Crystal Structure of 4-(3-methoxy-4-(prop-2-yn-1-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile Krunalkumar R. Mehariya, Bhagwati K. Gauni Mehariya Synthesis, Characterization, and Single Crystal Structure of 4-(3-methoxy-4-(prop-2-yn-1-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile Новинка

Krunalkumar R. Mehariya, Bhagwati K. Gauni Mehariya Synthesis, Characterization, and Single Crystal Structure of 4-(3-methoxy-4-(prop-2-yn-1-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile

1964 руб.
Scientific Essay from the year 2010 in the subject Chemistry - General, , language: English, abstract: This paper deals with the synthesis of some novel 1,4-Dihydropyride derivatives derivatives. The 1,4-Dicyanopyride (DHPM ) derivatives have been synthesized through novel synthetic process. The synthesized compound was well characterized by IR, 1H NMR and 13C NMR, Mass spectrometry. To know the absolute configuration of the synthesized compounds, X-Ray crystallography study was also performed by developing the crystal of the compounds.
Goossens Serge The Art of Credit Derivatives. Demystifying the Black Swan Goossens Serge The Art of Credit Derivatives. Demystifying the Black Swan Новинка

Goossens Serge The Art of Credit Derivatives. Demystifying the Black Swan

9899.42 руб.
Credit derivatives have been instrumental in the recent increase in securitization activity. The complex nature and the size of the market have given rise to very complex counterparty credit risks. The Lehman failure has shown that these issues can paralyse the financial markets, and the need for detailed understanding has never been greater. The Art of Credit Derivatives shows practitioners how to put a framework in place which will support the securitization activity. By showing the models that support this activity and linking them with very practical examples, the authors show why a mind-shift within the quant community is needed – a move from simple modeling to a more hands on mindset where the modeler understands the trading implicitly. The book has been written in five parts, covering the modeling framework; single name corporate credit derivatives; multi name corporate credit derivatives; asset backed securities and dynamic credit portfolio management. Coverage includes: groundbreaking solutions to the inherent risks associated with investing in securitization instruments how to use the standardized credit indices as the most appropriate instruments in price discovery processes and why these indices are the essential tools for short term credit portfolio management why the dynamics of systemic correlation and the standardised credit indices are linked with leverage, and consequently the implications for liquidity and solvability of financial institutions how Lévy processes and long term memory processes are related to the understanding of economic activity why regulatory capital should be portfolio dependant and how to use stress tests and scenario analysis to model this how to put structured products in a mark-to market-environment, increasing transparency for accounting and compliance. This book will be invaluable reading for Credit Analysts, Quantitative Analysts, Credit Portfolio Managers, Academics and anyone interested in these complex yet important markets.
Roy Rushikesh Syhthesis Of Pyrido-.2,3-d. Pyrimidine 2-one Derivatives Roy Rushikesh Syhthesis Of Pyrido-.2,3-d. Pyrimidine 2-one Derivatives Новинка

Roy Rushikesh Syhthesis Of Pyrido-.2,3-d. Pyrimidine 2-one Derivatives

5352 руб.
Over the last few years research has become more and more important due to its usefulness of society.This bool contain synthesis of heterocyclic compounds specially chalcones and various cyanoamine pyridines. This book mainly focus in synthesis of various pyrido[2,3-d]pyrimdine-2-one derivatives, characterization and biological activity of synthesized compounds.This book is useful for research students for whoever work in the field of organic chemistry.
Sumitra Nain, Sarvesh Paliwal, Prof D. Kishore Qsar of Pyrrolo Benzodiazepine Derivatives Sumitra Nain, Sarvesh Paliwal, Prof D. Kishore Qsar of Pyrrolo Benzodiazepine Derivatives Новинка

Sumitra Nain, Sarvesh Paliwal, Prof D. Kishore Qsar of Pyrrolo Benzodiazepine Derivatives

9052 руб.
Quantitative structure activity relationship studies are indubitably of great importance in modern chemistry. In pursuit of better anti-cancer agents QSAR studies were performed on a series of pyrrolo-benzodiazepine derivatives. The models were developed using training set compounds employing multiple linear regression and partial least square with many descriptors like electronic, topological, and geometrical. The developed models were evaluated for statistical significance and predictive power
Robert Kolb W. Financial Derivatives Robert Kolb W. Financial Derivatives Новинка

Robert Kolb W. Financial Derivatives

6692 руб.
Understand derivatives in a nonmathematical way Financial Derivatives, Third Edition gives readers a broad working knowledge of derivatives. For individuals who want to understand derivatives without getting bogged down in the mathematics surrounding their pricing and valuation Financial Derivatives, Third Edition is the perfect read. This comprehensive resource provides a thorough introduction to financial derivatives and their importance to risk management in a corporate setting.
Hossain Md. Selim Research Methodology for Natural Products Hossain Md. Selim Research Methodology for Natural Products Новинка

Hossain Md. Selim Research Methodology for Natural Products

8364 руб.
Most of the drugs today are obtained from natural sources or semi synthetic derivatives of natural products and used in the traditional systems of medicine.Here extraction methods, compound separations, detailed fractionation procedures are explained in a clear way. Various in vitro and in vivo biological testing methods such as anti-inflammatory, analgesic, antioxidants testing methods have been described.In addition to, antipyretic, anthelminthic, thrombolytic, anti-diarrheal, anxiolytic, anti microbial methods have been jot down to this work. Providing all pharmacological testing methods in one book, will attract the new researchers hopefully. Moreover, various marketed synthetic drugs produce liver toxicity which is a concerning issue to us & many plants are able to prevent liver damage which testing procedure has provided properly. Cancer is a public health problem all over the world. Large number of plants and their isolated constituents has been shown to potential anticancer activity and by thinking this one I have included anticancer method in this research too.
Wendy Pirie L. Derivatives Wendy Pirie L. Derivatives Новинка

Wendy Pirie L. Derivatives

6599.61 руб.
The complete guide to derivatives, from the experts at the CFA Derivatives is the definitive guide to derivatives, derivative markets, and the use of options in risk management. Written by the experts at the CFA Institute, this book provides authoritative reference for students and investment professionals seeking a deeper understanding for more comprehensive portfolio management. General discussion of the types of derivatives and their characteristics gives way to detailed examination of each market and its contracts, including forwards, futures, options, and swaps, followed by a look at credit derivatives markets and their instruments. Included lecture slides help bring this book directly into the classroom, while the companion workbook (sold separately) provides problems and solutions that align with the text and allows students to test their understanding while facilitating deeper internalization of the material. Derivatives have become essential to effective financial risk management, and create synthetic exposure to asset classes. This book builds a conceptual framework for understanding derivative fundamentals, with systematic coverage and detailed explanations. Understand the different types of derivatives and their characteristics Delve into the various markets and their associated contracts Examine the use of derivatives in portfolio management Learn why derivatives are increasingly fundamental to risk management The CFA Institute is the world's premier association for investment professionals, and the governing body for the CFA, CIPM, and Investment Foundations Programs. Those seeking a deeper understanding of the markets, mechanisms, and use of derivatives will value the level of expertise CFA lends to the discussion, providing a clear, comprehensive resource for students and professionals alike. Whether used alone or in conjunction with the companion workbook, Derivatives offers a complete course in derivatives and their markets.
Patel Amit B., Chikhalia Kishor, Kumari Premlata Quinazolines as potential bioactive agents Patel Amit B., Chikhalia Kishor, Kumari Premlata Quinazolines as potential bioactive agents Новинка

Patel Amit B., Chikhalia Kishor, Kumari Premlata Quinazolines as potential bioactive agents

6039 руб.
The proposed book gives an outline of the design, synthesis, characterization and various biological activities (antibacterial, antifungal, antituberculosis and anticancer) of novel urea/thiaourea functionalized quinazoline scaffolds. We have developed an efficient technique to introduced Suzuki C-C reaction on quinazoline and urea/thiourea moieties. The antimicrobial activity of synthesized analogs has been carried out against two Gram-positive bacteria, three Gram-negative bacteria and two fungi using paper disc diffusion method and agar streak dilution method. The synthesized analogs were further tested for their antimycobacterial activity against Mycobacterium tuberculosis H37RV using BACTEC MGIT and L. J. MIC methods. In addition, the synthesized analogs were also tested for their efficacy against prostate cancer PC3 cells using sulforhodamine B (SRB) assay to observe the variation in biological activity. The bioassay results revealed that majority of the compounds demonstrated excellent to moderate biological activity profiles. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR and mass spectrometric analysis.
Sarmento Bruno Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics Sarmento Bruno Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics Новинка

Sarmento Bruno Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics

17343.78 руб.
Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules – making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. Topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of DNA and siRNA target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional PEGylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues quality control and good manufacturing practice preclinical and clinical use of chitosan and derivatives for biopharmaceuticals Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.
Gordon Peery F. The Post-Reform Guide to Derivatives and Futures Gordon Peery F. The Post-Reform Guide to Derivatives and Futures Новинка

Gordon Peery F. The Post-Reform Guide to Derivatives and Futures

6269.63 руб.
An in-depth look at the best ways to navigate the post-reform world of derivatives and futures The derivatives market is one of the largest, and most important financial markets in the world. It's also one of the least understood. Today we are witnessing the unprecedented reform and reshaping of this market, and along with these events, the entire life cycle of a derivatives transaction has been affected. Accordingly, nearly all market participants in the modern economy need to view the handling of risk by derivatives in a very different way. Many aspects of financial services reform are based on a belief that derivatives caused the Great Recession of 2008. While the difficulties we now face cannot be blamed solely on derivatives, the need to understand this market, and the financial products that trade within it, has never been greater. The Post-Reform Guide to Derivatives and Futures provides straightforward descriptions of these important investment products, the market in which they trade, and the law that now, after July 16, 2011, governs their use in America and creates challenges for investors throughout the world. Author Gordon Peery is an attorney who works exclusively in the derivatives markets and specializes in derivatives and futures reform and market structure. Since representing clients in Congressional hearings involving Enron Corp., he has developed extensive experience in this field. With this guide, he reveals how derivatives law, and market practice throughout the world, began to change in historic ways beginning in 2011, and what you must do to keep up with these changes. Explains what derivatives and futures are, who trades them, and what must be done to manage risk in the post reform world Accurately reflects the futures and derivatives markets as they exist today and how they will be transformed by the Dodd-Frank Wall Street Reform and Consumer Protection Act Highlights the risks and common disputes regarding derivatives and futures, and offers recommendations for best practices in light of the evolving law governing derivatives The financial crisis has changed the rules of Wall Street, especially when it comes to derivatives and futures. The Post-Reform Guide to Derivatives and Futures will help you navigate this evolving field and put you in a better position to make the most informed decisions within it.
Kenneth Karlin D. Progress in Inorganic Chemistry Kenneth Karlin D. Progress in Inorganic Chemistry Новинка

Kenneth Karlin D. Progress in Inorganic Chemistry

13538.44 руб.
This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 57 continues to report recent advances with a significant, up-to-date selection of contributions from internationally-recognized researchers. The chapters of this volume are devoted to the following topics: Mechanisms of Water Oxidation Catalyzed by Ruthenium Coordination Complexes; Biomimetic and non-biological dinuclear Mx+-complex catalyzed alcoholysis reactions of phosphoryl transfer reactions; Photoactivated DNA Cleavage and Anticancer Activity of 3d-Metal Complexes; and more.
Sir Patrick Bijou How To Trade Derivatives And CFDs To Make Millions Sir Patrick Bijou How To Trade Derivatives And CFDs To Make Millions Новинка

Sir Patrick Bijou How To Trade Derivatives And CFDs To Make Millions

1439 руб.
Have you ever wondered how you can use derivatives and Contracts for Differences (CFDs) to make millions? I am sure you have heard of various forms of trading and how people have engaged in them to become rich. Well, this book provides all you need to know about derivatives and CFD trading.With the strategies and techniques outlined, you will have a detailed guide on how to start trading with derivatives and CFDs and how to earn millions from it. The book also shows you how to handle risks involved in trading and also how to ensure that you do not suffer losses while trading.This book is born from detailed research on derivatives and CFDs, observation of trends in trading over the past few decades and my personal proven techniques used trading derivatives and CFDs.
Don Chance M. Essays in Derivatives. Risk-Transfer Tools and Topics Made Easy Don Chance M. Essays in Derivatives. Risk-Transfer Tools and Topics Made Easy Новинка

Don Chance M. Essays in Derivatives. Risk-Transfer Tools and Topics Made Easy

3629.79 руб.
In the updated second edition of Don Chance’s well-received Essays in Derivatives, the author once again keeps derivatives simple enough for the beginner, but offers enough in-depth information to satisfy even the most experienced investor. This book provides up-to-date and detailed coverage of various financial products related to derivatives and contains completely new chapters covering subjects that include why derivatives are used, forward and futures pricing, operational risk, and best practices.
Andrew M. Chisholm Derivatives Demystified. A Step-by-Step Guide to Forwards, Futures, Swaps and Options Andrew M. Chisholm Derivatives Demystified. A Step-by-Step Guide to Forwards, Futures, Swaps and Options Новинка

Andrew M. Chisholm Derivatives Demystified. A Step-by-Step Guide to Forwards, Futures, Swaps and Options

6731.6 руб.
Derivatives are everywhere in the modern world and it is important for everyone in banking, investment and finance to have a good understanding of the subject. Derivatives Demystified provides a step-by-step guide to the subject, enabling the reader to have a solid, working understanding of key derivative products. Adopting a highly accessible approach, the author explains derivative products in straightforward terms and without the complex mathematics that underlie the subject, focusing on practical applications, case studies and examples of how the products are used to solve real-world problems. Derivatives Demystified follows a sequence that is designed to show that, although there are many applications of derivatives, there are only a small number of basic building blocks, namely forwards and futures, swaps and options. The book shows how each building block is applied to different markets and to the solution of various risk management and trading problems. This new edition will be fully revised to reflect the many changes the derivatives markets have seen over the last three years. New material will include a comprehensive history of derivatives, leading up to their use and abuse in the current credit crisis. It will also feature new chapters on regulation and control of derivatives, commodity derivatives, credit derivatives and structured products and new derivative markets including inflation linked and insurance linked products. Derivatives Demystified is essential reading for everyone who operates in the financial markets or within the corporate environment who requires a good understanding of these important financial instruments.
Rattan Tanu Mimani Inorganic Hydrazine Derivatives. Synthesis, Properties and Applications Rattan Tanu Mimani Inorganic Hydrazine Derivatives. Synthesis, Properties and Applications Новинка

Rattan Tanu Mimani Inorganic Hydrazine Derivatives. Synthesis, Properties and Applications

12275.27 руб.
Traditionally, interest in the chemistry of hydrazine and its derivatives has been focused on the development of propellants and explosives, but in recent years a wide variety of new applications have emerged in fields such as polymers, pharmaceuticals, water treatment, agriculture and medicine. Inorganic Hydrazine Derivatives: Synthesis, Properties and Applications presents a comprehensive review of the research carried out in this field during the last four decades. Methods for synthesizing inorganic hydrazine derivatives and complexes are systematically presented, together with details of their characterization, spectra, thermal analysis, crystal structure, and applications. Strong emphasis is given to controlling the reactivity of hydrazine derivatives from detonation to deflagration to decomposition. The monograph also highlights current developments and applications of inorganic hydrazine derivatives, including the synthesis of nanostructured materials. Topics covered include: An introduction to hydrazine and its inorganic derivatives Hydrazine salts Metal hydrazines Metal hydrazine carboxylates Hydrazinium metal complexes Applications of inorganic hydrazine derivatives This applications-based handbook is a valuable resource for academics and industry professionals researching and developing hydrazine compounds, high energy materials, nanomaterials, and pharmaceuticals.
Peter Carr Advanced Equity Derivatives. Volatility and Correlation Peter Carr Advanced Equity Derivatives. Volatility and Correlation Новинка

Peter Carr Advanced Equity Derivatives. Volatility and Correlation

10804.74 руб.
In Advanced Equity Derivatives: Volatility and Correlation, Sébastien Bossu reviews and explains the advanced concepts used for pricing and hedging equity exotic derivatives. Designed for financial modelers, option traders and sophisticated investors, the content covers the most important theoretical and practical extensions of the Black-Scholes model. Each chapter includes numerous illustrations and a short selection of problems, covering key topics such as implied volatility surface models, pricing with implied distributions, local volatility models, volatility derivatives, correlation measures, correlation trading, local correlation models and stochastic correlation. The author has a dual professional and academic background, making Advanced Equity Derivatives: Volatility and Correlation the perfect reference for quantitative researchers and mathematically savvy finance professionals looking to acquire an in-depth understanding of equity exotic derivatives pricing and hedging.
Gunter Meissner Credit Derivatives. Application, Pricing, and Risk Management Gunter Meissner Credit Derivatives. Application, Pricing, and Risk Management Новинка

Gunter Meissner Credit Derivatives. Application, Pricing, and Risk Management

2213.51 руб.
The market for credit derivatives–financial instruments designed to transfer credit risk from one party to another–has grown exponentially in recent years, with volume expected to reach more than $4.8 trillion by 2004. With demand increasing from the private sector for finance professionals trained in the opportunities–and dangers–inherent in this fast-changing market, finance courses are already springing up to meet this need. Credit Derivatives: Explains the field of credit derivatives to business students with a background in finance Cites real-world examples throughout, reinforced by end-of-chapter questions and internet links to pricing models Provides a concise overview of the field that is ideal for instructors seeking to supplement traditional derivatives course material, as well as those looking to offer a stand-alone course on credit derivatives.
Wendy Pirie L. Derivatives Workbook Wendy Pirie L. Derivatives Workbook Новинка

Wendy Pirie L. Derivatives Workbook

2969.82 руб.
Apply practical derivatives knowledge to truly test your understanding Derivatives Workbook offers practical instruction for students and professionals seeking additional guidance on working with derivatives instruments. Created by CFA Institute as a companion to the comprehensive Derivatives text, this book helps you practice using what you've learned through problems that mimic real-world scenarios. Working with different derivatives instruments helps you gauge how well you understand the instruments' characteristics, both shared and unique; this intimate knowledge is essential to effective portfolio management, and this book provides an expertly-designed, low-stakes environment ideal for self-assessment. Derivatives—financial instruments that derive their value from the value of some underlying asset—have become increasingly important for effective risk management, and fundamental for creating synthetic exposures to asset classes. Whether you're a student aspiring to a career in finance, or a professional seeking a stronger skill set, this workbook is an invaluable tool for simulating the use of derivatives in everyday practice. Work more effectively with different types of derivative instruments Master the valuation of forward, future, options, and swap contracts Utilize options for risk management and portfolio optimization Explore the practical aspects of working within the derivatives markets As in other security markets, arbitrage and market efficiency play a critical role in derivative pricing. The experts at CFA Institute recognize the need for realistic, practical derivatives training that translates well into real-world practice; this workbook fills the gap with a wealth of practice problems that have value to both aspiring and practicing investment professionals. Derivatives Workbook provides authoritative training and comprehensive practical instruction on derivative instruments, their markets, and valuation.
R. Johnson Stafford Derivatives Markets and Analysis R. Johnson Stafford Derivatives Markets and Analysis Новинка

R. Johnson Stafford Derivatives Markets and Analysis

6269.63 руб.
A practical, informative guide to derivatives in the real world Derivatives is an exposition on investments, guiding you from the basic concepts, strategies, and fundamentals to a more detailed understanding of the advanced strategies and models. As part of Bloomberg Financial's three part series on securities, Derivatives focuses on derivative securities and the functionality of the Bloomberg system with regards to derivatives. You'll develop a tighter grasp of the more subtle complexities involved in the evaluation, selection, and management of derivatives, and gain the practical skillset necessary to apply your knowledge to real-world investment situations using the tools and techniques that dominate the industry. Instructions for using the widespread Bloomberg system are interwoven throughout, allowing you to directly apply the techniques and processes discussed using your own data. You'll learn the many analytical functions used to evaluate derivatives, and how these functions are applied within the context of each investment topic covered. All Bloomberg information appears in specified boxes embedded throughout the text, making it easy for you to find it quickly when you need or, or easily skip it in favor of the theory-based text. Managing securities in today's dynamic and innovative investment environment requires a strong understanding of how the increasing variety of securities, markets, strategies, and methodologies are used. This book gives you a more thorough understanding, and a practical skillset that investment managers need. Understand derivatives strategies and models from basic to advanced Apply Bloomberg information and analytical functions Learn how investment decisions are made in the real world Grasp the complexities of securities evaluation, selection, and management The financial and academic developments of the past twenty years have highlighted the challenge in acquiring a comprehensive understanding of investments and financial markets. Derivatives provides the detailed explanations you've been seeking, and the hands-on training the real world demands.
Leonardo Marroni Pricing and Hedging Financial Derivatives. A Guide for Practitioners Leonardo Marroni Pricing and Hedging Financial Derivatives. A Guide for Practitioners Новинка

Leonardo Marroni Pricing and Hedging Financial Derivatives. A Guide for Practitioners

6797.6 руб.
The only guide focusing entirely on practical approaches to pricing and hedging derivatives One valuable lesson of the financial crisis was that derivatives and risk practitioners don't really understand the products they're dealing with. Written by a practitioner for practitioners, this book delivers the kind of knowledge and skills traders and finance professionals need to fully understand derivatives and price and hedge them effectively. Most derivatives books are written by academics and are long on theory and short on the day-to-day realities of derivatives trading. Of the few practical guides available, very few of those cover pricing and hedging—two critical topics for traders. What matters to practitioners is what happens on the trading floor—information only seasoned practitioners such as authors Marroni and Perdomo can impart. Lays out proven derivatives pricing and hedging strategies and techniques for equities, FX, fixed income and commodities, as well as multi-assets and cross-assets Provides expert guidance on the development of structured products, supplemented with a range of practical examples Packed with real-life examples covering everything from option payout with delta hedging, to Monte Carlo procedures to common structured products payoffs The Companion Website features all of the examples from the book in Excel complete with source code
Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Новинка

Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology

11483.32 руб.
This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. Advances in Enzymology focuses on enzymes, the primary catalysts of life processes. The explanation of the behavior of enzymes can be found via studies of their chemical mechanisms and can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. The transglutaminases, first described in 1957, are a large, widely-distributed family of enzymes canonically responsible for the amidation/transamidation of protein side chains. The extraordinary diversity of names associated with various enzymatic activities now recognized and aggregated as transglutaminase bears witness to the remarkable diversity of biological roles associated with the activity, including myriad human diseases.
Jolly Phonics Activity Books: Set 1-7 (комплект из 7 книг) Jolly Phonics Activity Books: Set 1-7 (комплект из 7 книг) Новинка

Jolly Phonics Activity Books: Set 1-7 (комплект из 7 книг)

4422 руб.
The first in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds s, a, t, i, p, n.The second in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds c k, e, h, r, m, d.The third in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds g, o, u, l, f, b.The fourth in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds ai, j, oa, ie, ee, or.The fIfth in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds z, w, ng, v, oo, oo.The sixth in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds y, x, ch, sh, th, th.The seventh in a series of 7 activity books for kids. The 36 page activity book deals with one group of letter sounds qu, ou, oi, ue, er, ar. Рекомендуем!
Eric Chin Problems and Solutions in Mathematical Finance. Equity Derivatives, Volume 2 Eric Chin Problems and Solutions in Mathematical Finance. Equity Derivatives, Volume 2 Новинка

Eric Chin Problems and Solutions in Mathematical Finance. Equity Derivatives, Volume 2

4289.75 руб.
Detailed guidance on the mathematics behind equity derivatives Problems and Solutions in Mathematical Finance Volume II is an innovative reference for quantitative practitioners and students, providing guidance through a range of mathematical problems encountered in the finance industry. This volume focuses solely on equity derivatives problems, beginning with basic problems in derivatives securities before moving on to more advanced applications, including the construction of volatility surfaces to price exotic options. By providing a methodology for solving theoretical and practical problems, whilst explaining the limitations of financial models, this book helps readers to develop the skills they need to advance their careers. The text covers a wide range of derivatives pricing, such as European, American, Asian, Barrier and other exotic options. Extensive appendices provide a summary of important formulae from calculus, theory of probability, and differential equations, for the convenience of readers. As Volume II of the four-volume Problems and Solutions in Mathematical Finance series, this book provides clear explanation of the mathematics behind equity derivatives, in order to help readers gain a deeper understanding of their mechanics and a firmer grasp of the calculations. Review the fundamentals of equity derivatives Work through problems from basic securities to advanced exotics pricing Examine numerical methods and detailed derivations of closed-form solutions Utilise formulae for probability, differential equations, and more Mathematical finance relies on mathematical models, numerical methods, computational algorithms and simulations to make trading, hedging, and investment decisions. For the practitioners and graduate students of quantitative finance, Problems and Solutions in Mathematical Finance Volume II provides essential guidance principally towards the subject of equity derivatives.
Hendrik Grobath Should we fear derivatives. Hendrik Grobath Should we fear derivatives. Новинка

Hendrik Grobath Should we fear derivatives.

1677 руб.
Bachelor Thesis from the year 2011 in the subject Business economics - Banking, Stock Exchanges, Insurance, Accounting, grade: 1,0, University of Trier (Professur für Unternehmensfinanzierung und Kapitalmärkte ), language: English, abstract: This paper provides an up-to-date perspective on the credit derivatives market. It explains why financial institutions are active in this market and which positions they incorporate. Moreover, gaps in credit derivatives trading will be outlined. The findings will be used to assess the most commonly stated benefits and risks of credit derivatives. The potential linkages between credit derivatives and the financial crisis are also addressed. Lehman Brothers and AIG will be used as examples to answer the question on whether the distress of major financial institutions during the financial crisis can be related to credit derivatives. These institutions have been highly active in the credit derivatives market. Finally, it will be asked whether the findings in this paper are applicable for other over-the-counter (OTC) derivatives. This paper will come up with a conclusion on whether the benefits or risks of these instruments are prevailing and suggests ways on how regulators should address OTC markets in the future.
Pei Dang Time-Frequency Analysis Based on Mono-Components Pei Dang Time-Frequency Analysis Based on Mono-Components Новинка

Pei Dang Time-Frequency Analysis Based on Mono-Components

9939 руб.
In this study, we define phase derivatives of analytic signals through non-tangential boundary limits, and consequently raise a new type of derivatives called Hardy-Sobolev derivatives for signals in the related Sobolev spaces. We prove that signals in the Sobolev spaces have well-defined phase derivatives that reduce to the classical ones when the latter exist. Based on the study of several types of phase derivatives and their properties, we mainly work on the following three subjects: (1)We extend the existing relations between the instantaneous frequency and the Fourier frequency and the related ones for smooth signals to those in the Sobolev spaces. (2) Based on the phase derivative theory and the recent result of positivity of phase derivatives of boundary limits of inner functions the theoretical foundation of all-pass filters and signals of minimum phase is established. Both the discrete and continuous signals cases are rigorously treated. (3) We study a particular type of time-frequency distribution exclusively suitable for mono-components, called transient time-frequency distribution(TTFD). For multi-components we carry on a corresponding study.
Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Новинка

Ji Zhang Macrocyclic Polyamines. Synthesis and Applications

12734.89 руб.
The first comprehensive book focusing on synthesis and applications of macrocyclic polyamines and their derivatives Macrocyclic polyamines are a class of widely used important compounds. This is the first book that systematically summarizes the synthesis and applications of macrocyclic polyamines and their analogues, including the properties and synthetic methods of macrocyclic polyamines, chemical nucleases based on macrocyclic polyamines, the derivatives of macrocyclic polyamines as nano-vector materials, macrocyclic polyamines derivatives for bio-imaging, chemical sensors based on macrocyclic polyamines, and other applications of macrocyclic polyamines. Macrocyclic Polyamines: Synthesis and Applications includes most of the studies involving macrocyclic polyamines and their derivatives, and may be used as a reference for the researchers in related fields. It offers in-depth coverage of cyclization modes; special procedures for tetraza macrocyclic compounds; diacids-diamines condensation; oxidative DNA cleaving by macrocyclic polyamines; lipids with cationic MPA headgroups; the derivatives of DOTA, DO3A, and PCTA; receptors for anions; sensors for bioactive molecules; macrocyclic polyamines for solvent extraction and membrane transport of amino acids and their derivatives, electrophoretic separation, and open-tubular CEC; and much more. The first book that systematically summarizes the chemistry of macrocyclic polyamines and their derivatives in terms of synthetic methods for their preparation, functionalization, and application in the main fields of chemical sensors, chemical nucleases, drug-delivery, bio-imaging and vector materials Provides a comprehensive reference for the researchers working on macrocyclic polyamines Offers train of thought in related research fields such as organic chemistry, coordination chemistry, analytical chemistry, supramolecular chemistry, biomaterials, etc. Macrocyclic Polyamines: Synthesis and Applications will not only provide a reference for the researchers working on macrocyclic polyamines, but also offer opportunities for researchers in related research fields to understand the benefits of these key compounds.
Vora Jabali J., Parmar Ketan C., Patel Dharmesh Synthesis of sulfur based Chalcone Derivatives Vora Jabali J., Parmar Ketan C., Patel Dharmesh Synthesis of sulfur based Chalcone Derivatives Новинка

Vora Jabali J., Parmar Ketan C., Patel Dharmesh Synthesis of sulfur based Chalcone Derivatives

10139 руб.
This book is consist of mainly two chapter. The first chapter is for general introduction of drugs, which generally narrates about heterocyclic compounds. The second chapter is for synthesis and characterization of chalcones as well as antimicrobial activity of synthesized chalcones. This book is useful to the research students who ever working in the field of synthetic organic chemistry(heterocyclic compounds).
Robert Whaley E. Derivatives. Markets, Valuation, and Risk Management Robert Whaley E. Derivatives. Markets, Valuation, and Risk Management Новинка

Robert Whaley E. Derivatives. Markets, Valuation, and Risk Management

13859.18 руб.
Robert Whaley has more than twenty-five years of experience in the world of finance, and with this book he shares his hard-won knowledge in the field of derivatives with you. Divided into ten information-packed parts, Derivatives shows you how this financial tool can be used in practice to create risk management, valuation, and investment solutions that are appropriate for a variety of market situations.
Sebastien Bossu An Introduction to Equity Derivatives. Theory and Practice Sebastien Bossu An Introduction to Equity Derivatives. Theory and Practice Новинка

Sebastien Bossu An Introduction to Equity Derivatives. Theory and Practice

5015.7 руб.
Everything you need to get a grip on the complex world of derivatives Written by the internationally respected academic/finance professional author team of Sebastien Bossu and Philipe Henrotte, An Introduction to Equity Derivatives is the fully updated and expanded second edition of the popular Finance and Derivatives. It covers all of the fundamentals of quantitative finance clearly and concisely without going into unnecessary technical detail. Designed for both new practitioners and students, it requires no prior background in finance and features twelve chapters of gradually increasing difficulty, beginning with basic principles of interest rate and discounting, and ending with advanced concepts in derivatives, volatility trading, and exotic products. Each chapter includes numerous illustrations and exercises accompanied by the relevant financial theory. Topics covered include present value, arbitrage pricing, portfolio theory, derivates pricing, delta-hedging, the Black-Scholes model, and more. An excellent resource for finance professionals and investors looking to acquire an understanding of financial derivatives theory and practice Completely revised and updated with new chapters, including coverage of cutting-edge concepts in volatility trading and exotic products An accompanying website is available which contains additional resources including powerpoint slides and spreadsheets. Visit www.introeqd.com for details.
Giles Jewitt FX Derivatives Trader School Giles Jewitt FX Derivatives Trader School Новинка

Giles Jewitt FX Derivatives Trader School

6269.63 руб.
An essential guide to real-world derivatives trading FX Derivatives Trader School is the definitive guide to the technical and practical knowledge required for successful foreign exchange derivatives trading. Accessible in style and comprehensive in coverage, the book guides the reader through both basic and advanced derivative pricing and risk management topics. The basics of financial markets and trading are covered, plus practical derivatives mathematics is introduced with reference to real-world trading and risk management. Derivative contracts are covered in detail from a trader's perspective using risk profiles and pricing under different derivative models. Analysis is approached generically to enable new products to be understood by breaking the risk into fundamental building blocks. To assist with learning, the book also contains Excel practicals which will deepen understanding and help build useful skills. The book covers of a wide variety of topics, including: Derivative exposures within risk management Volatility surface construction Implied volatility and correlation risk Practical tips for students on trading internships and junior traders Market analysis techniques FX derivatives trading requires mathematical aptitude, risk management skill, and the ability to work quickly and accurately under pressure. There is a tremendous gap between option pricing formulas and the knowledge required to be a successful derivatives trader. FX Derivatives Trader School is unique in bridging that gap.
Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications Новинка

Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications

15050.19 руб.
Intense research has been started all around the world in the past few decades to exploit different agents from natural products as eco-friendly alternative to synthetic and toxic chemicals. Natural products and their derivatives have received increasing attention for their use in many everyday applications ranging from food, medicine, textiles, and healthcare.This new book presents significant research advances about the use of natural products, mainly plant colorants, bioactive compounds and other plant extracts in the textile coloration, food, bioremediation and environmental applications. There are total eight chapters contributed by leading researchers covering the topics such as potential resurgence of natural dyes in applied fields, natural colorants from indigoid plants, phytochemistry of dye yielding plants, irradiation as novel pretreatment methods, dyeing studies with henna plant, phytoremediation of arsenic, and synthesis of curcumin complexes for medicinal and other industrial uses.
Patel Tarun, Shah Shailesh, A. M. Patel Novel Heterocyclic Compounds-2 Patel Tarun, Shah Shailesh, A. M. Patel Novel Heterocyclic Compounds-2 Новинка

Patel Tarun, Shah Shailesh, A. M. Patel Novel Heterocyclic Compounds-2

8652 руб.
Introductory: The books is suggested that it is appropriate to give the brief note about hereto cyclic compounds bearing Trazine, Altretamine, Triethylenemelamine, Melamine, Atrazine, 4-aminobenzene-1-sulfonyl chloride and azetidinone derivatives disussions.this book is useful for those researcher who are involved to work in such compounds. Heterocyclic compounds of melamine work is also included in this book.
Abd El-Gilil Shimaa M., Sarg Marwa T., Bashandy Mahmoud S. Pyrrole and pyrrolopyrimidine derivatives Abd El-Gilil Shimaa M., Sarg Marwa T., Bashandy Mahmoud S. Pyrrole and pyrrolopyrimidine derivatives Новинка

Abd El-Gilil Shimaa M., Sarg Marwa T., Bashandy Mahmoud S. Pyrrole and pyrrolopyrimidine derivatives

5202 руб.
Pyrrole and pyrrolopyrimidine derivatives are important and versatile compounds. The main objective of the present book is to provide an overview in the synthesis and reactions of pyrrole and pyrrolopyrimidine derivatives and their used in medicine and study their Pharmacological activities such as "Anti-inflammatory, Analgesic, Antimicrobial, Anti-hepatoprotective, Anti-hyperglycemic, Anti-cancer and Anti-viral activities".
Justin London Modeling Derivatives in C++ Justin London Modeling Derivatives in C++ Новинка

Justin London Modeling Derivatives in C++

7919.53 руб.
This book is the definitive and most comprehensive guide to modeling derivatives in C++ today. Providing readers with not only the theory and math behind the models, as well as the fundamental concepts of financial engineering, but also actual robust object-oriented C++ code, this is a practical introduction to the most important derivative models used in practice today, including equity (standard and exotics including barrier, lookback, and Asian) and fixed income (bonds, caps, swaptions, swaps, credit) derivatives. The book provides complete C++ implementations for many of the most important derivatives and interest rate pricing models used on Wall Street including Hull-White, BDT, CIR, HJM, and LIBOR Market Model. London illustrates the practical and efficient implementations of these models in real-world situations and discusses the mathematical underpinnings and derivation of the models in a detailed yet accessible manner illustrated by many examples with numerical data as well as real market data. A companion CD contains quantitative libraries, tools, applications, and resources that will be of value to those doing quantitative programming and analysis in C++. Filled with practical advice and helpful tools, Modeling Derivatives in C++ will help readers succeed in understanding and implementing C++ when modeling all types of derivatives.
Frank J. Biel, Frank J. Beil Accounting for Derivatives and Hedging Activities Frank J. Biel, Frank J. Beil Accounting for Derivatives and Hedging Activities Новинка

Frank J. Biel, Frank J. Beil Accounting for Derivatives and Hedging Activities

4514 руб.
Derivatives, and derivatives used to hedge financial and operating functions, are designed to allow managers of firms to manage effectively the downside risk of their financial and operating strategies. They also can be very useful tools that allow managers and executives to accurately predict financial and operational performance and manage the investment communities' "expectations" regarding overall firm performance. Derivatives and hedges, however, if not properly designed in conjunction with the firm's risk management strategy, can be potentially disastrous for the firm. The ongoing financial turmoil in markets can be partially explained by company managers and executives not understanding the potential financial statement impact when derivative markets move in a particular direction for longer periods of time than anticipated by firms. This book is designed for managers and executives to be a comprehensive yet accessible resource for understanding the impact of derivative and hedge accounting on a company's reporting of financial statements. The book's primary purpose is to demystify derivatives and provide practical advice and counsel on how to use them to manage more effectively the operational and financial risk to the firm. When used properly derivatives are an extremely effective tool that managers and executives can use to reduce uncertainty regarding the future.
Moorad Choudhry Fixed-Income Securities and Derivatives Handbook Moorad Choudhry Fixed-Income Securities and Derivatives Handbook Новинка

Moorad Choudhry Fixed-Income Securities and Derivatives Handbook

6929.59 руб.
The definitive guide to fixed-come securities-revised to reflect today's dynamic financial environment The Second Edition of the Fixed-Income Securities and Derivatives Handbook offers a completely updated and revised look at an important area of today's financial world. In addition to providing an accessible description of the main elements of the debt market, concentrating on the instruments used and their applications, this edition takes into account the effect of the recent financial crisis on fixed income securities and derivatives. As timely as it is timeless, the Second Edition of the Fixed-Income Securities and Derivatives Handbook includes a wealth of new material on such topics as covered and convertible bonds, swaps, synthetic securitization, and bond portfolio management, as well as discussions regarding new regulatory twists and the evolving derivatives market. Offers a more detailed look at the basic principles of securitization and an updated chapter on collateralized debt obligations Covers bond mathematics, pricing and yield analytics, and term structure models Includes a new chapter on credit analysis and the different metrics used to measure bond-relative value Contains illustrative case studies and real-world examples of the topics touched upon throughout the book Written in a straightforward and accessible style, Moorad Choudhry's new book offers the ideal mix of practical tips and academic theory within this important field.
Dino World Puffy Sticker Activity Book Dino World Puffy Sticker Activity Book Новинка

Dino World Puffy Sticker Activity Book

986 руб.
Welcome to Dino World! The perfect activity book for young dinosaur enthusiasts. This dinosaur-themed activity book is packed with things to do! It includes 32-pages of colouring and doodling activities, 20 pages of dinosaur card press-outs, and a sheet of fabulous puffy stickers!
Borisov S., Voronkov M., Lukevits E. Organosilicon Derivatives of Phosphorus and Sulfur Borisov S., Voronkov M., Lukevits E. Organosilicon Derivatives of Phosphorus and Sulfur Новинка

Borisov S., Voronkov M., Lukevits E. Organosilicon Derivatives of Phosphorus and Sulfur

200 руб.
One of the characteristics of the development of chemical science in the middle of the present century is the vigorous pro gress of the "third chemistry," which is often named now the chemistry of heteroorganic compounds. Then in the last decade, among specialists in this field there has been a marked increase in interest in heteroatomic organic derivatives of silicon, i. e. , heteroorganic silicon compounds. However, until recently this new class of chemical substances, which is extremely interesting theoretically and practically, has been without a single specialized monograph which systematizes and generalizes all progress in the heteroorganic chemistry of silicon. The first attempt in this direction was our book "Heteroorganic Compounds of Silicon" [42 (F), 17 (S) *], which appeared at the end of 1966 and was published as an English translation in the USA in 1969. However, as follows from its subtitle "Derivatives of Inorganic Elements," this mono graph could not cover the whole broad field of the chemistry of heteroorganic compounds of silicon. The main reason for this was above all the abundance and variety of original investigations of organosilicon derivatives of inorganic elements, which was un expected even to the authors themselves. As a result of this the planned length of the book compelled us to omit the sections on organosilicon compounds of phosphorus and sulfur, which had al ready been prepared for publication.Издательство - Plenum press
Frederick Harris Antimicrobial Peptides Frederick Harris Antimicrobial Peptides Новинка

Frederick Harris Antimicrobial Peptides

13120.04 руб.
In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.
Maurie Markman Targeted Therapy in Translational Cancer Research Maurie Markman Targeted Therapy in Translational Cancer Research Новинка

Maurie Markman Targeted Therapy in Translational Cancer Research

11572.85 руб.
Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities
Amir Sadr Interest Rate Swaps and Their Derivatives. A Practitioner's Guide Amir Sadr Interest Rate Swaps and Their Derivatives. A Practitioner's Guide Новинка

Amir Sadr Interest Rate Swaps and Their Derivatives. A Practitioner's Guide

7127.58 руб.
An up-to-date look at the evolution of interest rate swaps and derivatives Interest Rate Swaps and Derivatives bridges the gap between the theory of these instruments and their actual use in day-to-day life. This comprehensive guide covers the main «rates» products, including swaps, options (cap/floors, swaptions), CMS products, and Bermudan callables. It also covers the main valuation techniques for the exotics/structured-notes area, which remains one of the most challenging parts of the market. Provides a balance of relevant theory and real-world trading instruments for rate swaps and swap derivatives Uses simple settings and illustrations to reveal key results Written by an experienced trader who has worked with swaps, options, and exotics With this book, author Amir Sadr shares his valuable insights with practitioners in the field of interest rate derivatives-from traders and marketers to those in operations.
Richard Flavell R. Swaps and Other Derivatives Richard Flavell R. Swaps and Other Derivatives Новинка

Richard Flavell R. Swaps and Other Derivatives

11166.54 руб.
Richard Flavell has a strong theoretical perspective on swaps with considerable practical experience in the actual trading of these instruments. This rare combination makes this welcome updated second edition a useful reference work for market practitioners. —Satyajit Das, author of Swaps and Financial Derivatives Library and Traders and Guns & Money: Knowns and Unknowns in the Dazzling World of Derivatives Fully revised and updated from the first edition, Swaps and Other Derivatives, Second Edition, provides a practical explanation of the pricing and evaluation of swaps and interest rate derivatives. Based on the author’s extensive experience in derivatives and risk management, working as a financial engineer, consultant and trainer for a wide range of institutions across the world this book discusses in detail how many of the wide range of swaps and other derivatives, such as yield curve, index amortisers, inflation-linked, cross-market, volatility, diff and quanto diffs, are priced and hedged. It also describes the modelling of interest rate curves, and the derivation of implied discount factors from both interest rate swap curves, and cross-currency adjusted curves. There are detailed sections on the risk management of swap and option portfolios using both traditional approaches and also Value-at-Risk. Techniques are provided for the construction of dynamic and robust hedges, using ideas drawn from mathematical programming. This second edition has expanded sections on the credit derivatives market – its mechanics, how credit default swaps may be priced and hedged, and how default probabilities may be derived from a market strip. It also prices complex swaps with embedded options, such as range accruals, Bermudan swaptions and target accrual redemption notes, by constructing detailed numerical models such as interest rate trees and LIBOR-based simulation. There is also increased discussion around the modelling of volatility smiles and surfaces. The book is accompanied by a CD-ROM where all the models are replicated, enabling readers to implement the models in practice with the minimum of effort.
A. Kim V. i-Smooth Analysis. Theory and Applications A. Kim V. i-Smooth Analysis. Theory and Applications Новинка

A. Kim V. i-Smooth Analysis. Theory and Applications

15050.19 руб.
The edition introduces a new class of invariant derivatives and shows their relationships with other derivatives, such as the Sobolev generalized derivative and the generalized derivative of the distribution theory. This is a new direction in mathematics. i-Smooth analysis is the branch of functional analysis that considers the theory and applications of the invariant derivatives of functions and functionals. The important direction of i-smooth analysis is the investigation of the relation of invariant derivatives with the Sobolev generalized derivative and the generalized derivative of distribution theory. Until now, i-smooth analysis has been developed mainly to apply to the theory of functional differential equations, and the goal of this book is to present i-smooth analysis as a branch of functional analysis. The notion of the invariant derivative (i-derivative) of nonlinear functionals has been introduced in mathematics, and this in turn developed the corresponding i-smooth calculus of functionals and showed that for linear continuous functionals the invariant derivative coincides with the generalized derivative of the distribution theory. This book intends to introduce this theory to the general mathematics, engineering, and physicist communities.
Dragons: Sticker Activity Book Dragons: Sticker Activity Book Новинка

Dragons: Sticker Activity Book

666 руб.
This action-packed activity book is full of your favourite dragons and vikings! Full of games, puzzles, colouring and more, this activity book will keep Dragons fans busy for hours!
R. Subramani Venkata Accounting for Investments, Fixed Income Securities and Interest Rate Derivatives. A Practitioner's Handbook R. Subramani Venkata Accounting for Investments, Fixed Income Securities and Interest Rate Derivatives. A Practitioner's Handbook Новинка

R. Subramani Venkata Accounting for Investments, Fixed Income Securities and Interest Rate Derivatives. A Practitioner's Handbook

14967.92 руб.
A comprehensive guide to new and existing accounting practices for fixed income securities and interest rate derivatives The financial crisis forced accounting standard setters and market regulators around the globe to come up with new proposals for modifying existing practices for investment accounting. Accounting for Investments, Volume 2: Fixed Income and Interest Rate Derivatives covers these revised standards, as well as those not yet implemented, in detail. Beginning with an overview of the financial products affected by these changes—defining each product, the way it is structured, its advantages and disadvantages, and the different events in the trade life cycle—the book then examines the information that anyone, person or institution, holding fixed income security and interest rate investments must record. Offers a comprehensive overview of financial products including fixed income and interest rate derivatives like interest rate swaps, caps, floors, collars, cross currency swaps, and more Follows the trade life cycle of each product Explains how new and anticipated changes in investment accounting affect the investment world Accurately recording and reporting investments across financial products requires extensive knowledge both of new and existing practices, and Accounting for Investments, Volume 2, Fixed Income Securities and Interest Rate Derivatives covers this important topic in-depth, making it an invaluable resource for professional and novice accountants alike.
Pageni Parasmani Synthesis of Ester Derivatives of Resveratrol Pageni Parasmani Synthesis of Ester Derivatives of Resveratrol Новинка

Pageni Parasmani Synthesis of Ester Derivatives of Resveratrol

6452 руб.
Resveratrol is a naturally occurring polyphenol of stilbene family. It is produced by various plants in response to stress, UV radiation and fungal attack. It is primarily found in peanuts, berries, grape skin and red wine. Even though it has been found to exhibit anti-cancer, anti-inflammatory, anti-aging, and anti-oxidant properties, its solubility and bioavailability is limited. Efforts have been made to synthesize noble ester derivatives of resveratrol.
Tasiu Isah Sod and Catalase Activity During in Vitro Morphogenesis of C. Bicolor Tasiu Isah Sod and Catalase Activity During in Vitro Morphogenesis of C. Bicolor Новинка

Tasiu Isah Sod and Catalase Activity During in Vitro Morphogenesis of C. Bicolor

9189 руб.
Evolution of aerobic metabolism such as respiration and photosynthesis resulted in generation of reactive oxygen species (ROS) which has a damaging effect on macromolecules and plasma membrane. To counteract the effect caused by ROS, SOD and catalase are enzymes evolved for the scavenging of ROS.Catalase decomposes the product of SOD activity into H2O and H.Activities of SOD and Catalase enzymes during in vitro morphogenesis of C. bicolor on MS medium supplemented with 0.3mg/L NAA and BAP was carried out. Callus induction, somatic embryogenesis and plantlet regeneration was obtained on these medium.For the study of SOD and Catalase activities, callus,somatic embryos (SEs) and regenerated plantlet samples were taken.SOD activity was highest in SEs,it decreased sharply during plantletregeneration time and lowest activity was recorded in callus.Catalase activity was very low in callus, it doubled in SEs and maximum of CAT activity was observed in the regenerated plantlet.Somatic embryogenesis seems to require more activity of SOD and shoot organogenesis seems to require more of catalase activity.
Daniel Rosch Credit Securitisations and Derivatives. Challenges for the Global Markets Daniel Rosch Credit Securitisations and Derivatives. Challenges for the Global Markets Новинка

Daniel Rosch Credit Securitisations and Derivatives. Challenges for the Global Markets

8249.51 руб.
A comprehensive resource providing extensive coverage of the state of the art in credit secruritisations, derivatives, and risk management Credit Securitisations and Derivatives is a one-stop resource presenting the very latest thinking and developments in the field of credit risk. Written by leading thinkers from academia, the industry, and the regulatory environment, the book tackles areas such as business cycles; correlation modelling and interactions between financial markets, institutions, and instruments in relation to securitisations and credit derivatives; credit portfolio risk; credit portfolio risk tranching; credit ratings for securitisations; counterparty credit risk and clearing of derivatives contracts and liquidity risk. As well as a thorough analysis of the existing models used in the industry, the book will also draw on real life cases to illustrate model performance under different parameters and the impact that using the wrong risk measures can have.
Maren Urner Investigating the dynamic role of fluctuations in ongoing activity in the human brain Maren Urner Investigating the dynamic role of fluctuations in ongoing activity in the human brain Новинка

Maren Urner Investigating the dynamic role of fluctuations in ongoing activity in the human brain

5877 руб.
Doctoral Thesis / Dissertation from the year 2013 in the subject Medicine - Neurology, Psychiatry, Addiction, grade: pass (in GB keine Benotung), University College London (Institute of Cognitive Neuroscience), course: Neurowissenschaften, language: English, abstract: Traditionally, the focus in cognitive neuroscience has been on so-called evoked neural activity in response to certain stimuli or experiences. However, most of the brain's activity is actually spontaneous and therefore not ascribed to the processing of a certain task or stimulus - or in other words, uncoupled to overt stimuli or motor outputs. In this thesis I investigated the functional role of spontaneous activity with a focus on its role in contextual changes ranging from recent experiences of individuals to trial-by-trial variability in a certain task. I studied the nature of ongoing activity from two perspectives: One looking at changes in the ongoing activity due to learning, and the other one looking at the predictive role of prestimulus activity using different methodologies, i.e. EEG and fMRI. Finally, I ventured into the realm of inter-individual differences and mind-wandering to investigate the relationship between ongoing activity, certain behavioural traits and neuronal connectivity.
My Horse and Pony. Activity and Sticker book My Horse and Pony. Activity and Sticker book Новинка

My Horse and Pony. Activity and Sticker book

732 руб.
Horses and ponies activities for hours of fun! Includes hundreds of beautiful stickers. Have fun with this beautiful horse and pony activity book, packed full of colourful stickers. Match the horses to their shadows, colour in the riding show, help the ponies through the maze and much more! Bloomsbury Activity Books provide hours of colouring, stickering and activity fun for boys and girls alike. Every book includes enchanting, bright and beautiful illustrations which children and parents will find very hard to resist. Perfect for providing entertainment at home or on the move!
Ralf Koschmieder, Furong Liang The empirical relationship between the spreads of Credit Default Swaps and Bonds Ralf Koschmieder, Furong Liang The empirical relationship between the spreads of Credit Default Swaps and Bonds Новинка

Ralf Koschmieder, Furong Liang The empirical relationship between the spreads of Credit Default Swaps and Bonds

3314 руб.
Scientific Essay from the year 2010 in the subject Business economics - Investment and Finance, , language: English, abstract: Warren Buffet, the world's richest man, once said that derivatives are financial "weapons of mass destruction." a term popularized by George W. Bush to describe nuclear arms. Indeed financial derivatives have a far greater impact on the market than their underlying due to their leverage effect. And the most popular and important credit derivatives nowadays are credit default swaps with a current notional value of over 60 trillion US dollars according to ISDA 1 (International Swaps and Derivatives Association) and 58 trillion US dollars according to BIS 2 (Bank for international settlement) respectively. That is more than the whole world's gross domestic product in the same year! 3 This paper examines the empirical relationship of CDS premium and credit spread by testing on their theoretical equivalence derived by Duffie (1999). It begins with an overview of CDS followed by the theoretical framework. The analysis starts with explanation of testing methods and description of data. After confirming the existence of the basis spread, this paper goes on to analyse the interactions of CDS spread and Bond spread using econometrics methods like Cointegration and Granger Causality tests. Also examined is the leadership of price discovery process between CDS market and traditional bond market.
Anticancer Living. The Six Step Solution to Transform Your Health Anticancer Living. The Six Step Solution to Transform Your Health Новинка

Anticancer Living. The Six Step Solution to Transform Your Health

1029 руб.
“You have cancer.” These are perhaps the most feared three words that will ever come out of a doctor’s mouth, and more and more people are hearing them. Yet most patients (and some doctors) do not realize that lifestyle changes can dramatically reduce risk, assist treatment and improve chances of surviving and even thriving after a diagnosis.  Over the course of a major study Servan-Schreiber designed with Dr Lorenzo Cohen at the MD Anderson Cancer Center, six key areas have emerged: love and social support, stress management, rest, movement, nutrition and avoiding environmental toxins. Each plays a role--but it's the synergies created by this potent "Mix of Six" that can bring about real shifts in health and well-being, significantly improving quality of life and positively supporting conventional cancer treatments. Dr. David Servan-Schreiber's Anticancer introduced a revolutionary way to understand and confront cancer, changing the lives of millions around the world. He laid out the principles of integrative care that had allowed him to live many years beyond expectations for his own cancer, but readers have long requested a specific plan to implement his approach. Anticancer Living is that book.

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Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules – making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. Topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of DNA and siRNA target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional PEGylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues quality control and good manufacturing practice preclinical and clinical use of chitosan and derivatives for biopharmaceuticals Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.
Продажа invitro anticancer activity of novel thiadiazole derivatives лучших цены всего мира
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