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Herman Lam Practical Approaches to Method Validation and Essential Instrument Qualification Herman Lam Practical Approaches to Method Validation and Essential Instrument Qualification Новинка

Herman Lam Practical Approaches to Method Validation and Essential Instrument Qualification

8781.72 руб.
Practical approaches to ensure that analytical methods and instruments meet GMP standards and requirements Complementing the authors' first book, Analytical Method Validation and Instrument Performance Verification, this new volume provides coverage of more advanced topics, focusing on additional and supplemental methods, instruments, and electronic systems that are used in pharmaceutical, biopharmaceutical, and clinical testing. Readers will gain new and valuable insights that enable them to avoid common pitfalls in order to seamlessly conduct analytical method validation as well as instrument operation qualification and performance verification. Part 1, Method Validation, begins with an overview of the book's risk-based approach to phase appropriate validation and instrument qualification; it then focuses on the strategies and requirements for early phase drug development, including validation of specific techniques and functions such as process analytical technology, cleaning validation, and validation of laboratory information management systems Part 2, Instrument Performance Verification, explores the underlying principles and techniques for verifying instrument performance—coverage includes analytical instruments that are increasingly important to the pharmaceutical industry, such as NIR spectrometers and particle size analyzers—and offers readers a variety of alternative approaches for the successful verification of instrument performance based on the needs of their labs At the end of each chapter, the authors examine important practical problems and share their solutions. All the methods covered in this book follow Good Analytical Practices (GAP) to ensure that reliable data are generated in compliance with current Good Manufacturing Practices (cGMP). Analysts, scientists, engineers, technologists, and technical managers should turn to this book to ensure that analytical methods and instruments are accurate and meet GMP standards and requirements.
Joachim Ermer Method Validation in Pharmaceutical Analysis. A Guide to Best Practice Joachim Ermer Method Validation in Pharmaceutical Analysis. A Guide to Best Practice Новинка

Joachim Ermer Method Validation in Pharmaceutical Analysis. A Guide to Best Practice

15259.94 руб.
This second edition of a global bestseller has been completely redesigned and extensively rewritten to take into account the new Quality by Design (QbD) and lifecycle concepts in pharmaceutical manufacturing. As in the first edition, the fundamental requirements for analytical method validation are covered, but the second edition describes how these are applied systematically throughout the entire analytical lifecycle. QbD principles require adoption of a systematic approach to development and validation that begin with predefined objectives. For analytical methods these predefined objectives are established as an Analytical Target Profile (ATP). The book chapters are aligned with recently introduced standards and guidelines for manufacturing processes validation and follow the three stages of the analytical lifecycle: Method Design, Method Performance Qualification, and Continued Method Performance Verification. Case studies and examples from the pharmaceutical industry illustrate the concepts and guidelines presented, and the standards and regulations from the US (FDA), European (EMA) and global (ICH) regulatory authorities are considered throughout. The undisputed gold standard in the field.
Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena Новинка

Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena

10382.92 руб.
A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.
Madden Timothy L. Analytical Methods for Therapeutic Drug Monitoring and Toxicology Madden Timothy L. Analytical Methods for Therapeutic Drug Monitoring and Toxicology Новинка

Madden Timothy L. Analytical Methods for Therapeutic Drug Monitoring and Toxicology

13497.8 руб.
This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatography (UPLC) coupled with UV (UPLC-UV) detection and mass spectrometry (UPLC-MS/MS). With more detailed and complete summaries than sketchy and abbreviated formats used in the other books, this book provides a thorough description of method validation and results, as well as the operating parameters.
Harald Seitz Biomarker Validation. Technological, Clinical and Commercial Aspects Harald Seitz Biomarker Validation. Technological, Clinical and Commercial Aspects Новинка

Harald Seitz Biomarker Validation. Technological, Clinical and Commercial Aspects

11877.41 руб.
Built on a decade of experience with novel molecular diagnostics, this practice-oriented guide shows how to cope with validation issues during all stages of biomarker development, from the first clinical studies to the eventual commercialization of a new diagnostic test.
Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient Новинка

Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient

12596.53 руб.
Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs , instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives Brings together the most current advances in the mass spectrometry technology and related method in protein analysis
Sean Ekins Predictive Approaches in Drug Discovery and Development. Biomarkers and In Vitro / In Vivo Correlations Sean Ekins Predictive Approaches in Drug Discovery and Development. Biomarkers and In Vitro / In Vivo Correlations Новинка

Sean Ekins Predictive Approaches in Drug Discovery and Development. Biomarkers and In Vitro / In Vivo Correlations

10797.03 руб.
Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
Litwin Virginia Flow Cytometry in Drug Discovery and Development Litwin Virginia Flow Cytometry in Drug Discovery and Development Новинка

Litwin Virginia Flow Cytometry in Drug Discovery and Development

10308.76 руб.
This book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The third section contains a single chapter presenting an in depth discussion of validation considerations and regulatory compliance issues associated with drug development.
Herbert W. Seliger Second Language Research Methods Herbert W. Seliger Second Language Research Methods Новинка

Herbert W. Seliger Second Language Research Methods

2703.41 руб.
Based on a set of four research parameters, this book discusses the development of research questions and hypotheses, naturalistic and experimental research, data collection, and validation of research instruments. Each chapter includes examples and activities.
Dominique Bonneau Thermo-hydrodynamic Lubrication in Hydrodynamic Bearings Dominique Bonneau Thermo-hydrodynamic Lubrication in Hydrodynamic Bearings Новинка

Dominique Bonneau Thermo-hydrodynamic Lubrication in Hydrodynamic Bearings

7050.51 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book describes the thermo-hydrodynamic and the thermo-elasto-hydrodynamic lubrication. The algorithms are methodically detailed and each section is thoroughly illustrated.
David Elder ICH Quality Guidelines. An Implementation Guide David Elder ICH Quality Guidelines. An Implementation Guide Новинка

David Elder ICH Quality Guidelines. An Implementation Guide

25193.07 руб.
Examining the implications and practical implementation of multi-disciplinary International Conference on Harmonization (ICH) topics, this book gives an integrated view of how the guidelines inform drug development strategic planning and decision-making. • Addresses a consistent need for interpretation, training, and implementation examples of ICH guidelines via case studies • Offers a primary reference point for practitioners addressing the dual challenge of interpretation and practical implementation of ICH guidelines • Uses case studies to help readers understand and apply ICH guidelines • Provides valuable insights into guidelines development, with chapters by authors involved in generating or with experience implementing the guidelines • Includes coverage of stability testing, analytical method validation, impurities, biotechnology drugs and products, and good manufacturing practice (GMP)
Guoping Wang Transfer Matrix Method for Multibody Systems. Theory and Applications Guoping Wang Transfer Matrix Method for Multibody Systems. Theory and Applications Новинка

Guoping Wang Transfer Matrix Method for Multibody Systems. Theory and Applications

14239.43 руб.
TRANSFER MATRIX METHOD FOR MULTIBODY SYSTEMS: THEORY AND APPLICATIONS Xiaoting Rui, Guoping Wang and Jianshu Zhang – Nanjing University of Science and Technology, China Featuring a new method of multibody system dynamics, this book introduces the transfer matrix method systematically for the first time. First developed by the lead author and his research team, this method has found numerous engineering and technological applications. Readers are first introduced to fundamental concepts like the body dynamics equation, augmented operator and augmented eigenvector before going in depth into precision analysis and computations of eigenvalue problems as well as dynamic responses. The book also covers a combination of mixed methods and practical applications in multiple rocket launch systems, self-propelled artillery as well as launch dynamics of on-ship weaponry. • Comprehensively introduces a new method of analyzing multibody dynamics for engineers • Provides a logical development of the transfer matrix method as applied to the dynamics of multibody systems that consist of interconnected bodies • Features varied applications in weaponry, aeronautics, astronautics, vehicles and robotics Written by an internationally renowned author and research team with many years' experience in multibody systems Transfer Matrix Method of Multibody System and Its Applications is an advanced level text for researchers and engineers in mechanical system dynamics. It is a comprehensive reference for advanced students and researchers in the related fields of aerospace, vehicle, robotics and weaponry engineering.
Abbie Griffin Open Innovation. New Product Development Essentials from the PDMA Abbie Griffin Open Innovation. New Product Development Essentials from the PDMA Новинка

Abbie Griffin Open Innovation. New Product Development Essentials from the PDMA

4318.81 руб.
A clear, practical guide to implementing Open Innovation for new product development Open Innovation: New Product Development Essentials from the PDMA is a comprehensive guide to the theory and practice of the Open Innovation method. Written by experts from the Product Development and Management Association, the book packages a collection of Open Innovation tools in a digestible and actionable format. Real-world case studies drawn from the authors' own successes and failures illustrate the concepts presented, providing accurate representation of the opportunities and challenges of Open Innovation implementation. Key tools are presented with a focus on immediate applications for business, allowing NPD professionals to easily discern where this cutting edge development method can push innovation forward. Open Innovation assumes that companies can and should use both internal and external ideas and paths to market, permeating the boundaries between firm and environment. Innovations transfer outward and inward through purchase, licensing, joint ventures, and spin-offs, allowing companies to expand beyond their own research and dramatically improve productivity through collaboration. PDMA Essentials provides practical guidance on exploiting the Open Innovation model to these ends, with clear guidance on all aspects of the new product development process. Topics include: Product platforming and idea competitions Customer immersion and interaction Collaborative product design and development Innovation networks, rewards, and incentives Many practitioners charged with innovation have only a vague understanding of the specific tools available for Open Innovation, and how they might be applied. As the marketplace shifts dramatically to keep pace with changing consumer behaviors, remaining relevant increasingly means ramping up innovation processes. PDMA Essentials provides the tools NPD practitioners need to implement a leading innovation method, and drive continued growth.
Kostas Nikolopoulos I. Forecasting With The Theta Method. Theory and Applications Kostas Nikolopoulos I. Forecasting With The Theta Method. Theory and Applications Новинка

Kostas Nikolopoulos I. Forecasting With The Theta Method. Theory and Applications

8009.68 руб.
The first book to be published on the Theta method, outlining under what conditions the method outperforms other forecasting methods This book is the first to detail the Theta method of forecasting – one of the most difficult-to-beat forecasting benchmarks, which topped the biggest forecasting competition in the world in 2000: the M3 competition. Written by two of the leading experts in the forecasting field, it illuminates the exact replication of the method and under what conditions the method outperforms other forecasting methods. Recent developments such as multivariate models are also included, as are a series of practical applications in finance, economics, and healthcare. The book also offers practical tools in MS Excel and guidance, as well as provisional access, for the use of R source code and respective packages. Forecasting with the Theta Method: Theory and Applications includes three main parts. The first part, titled Theory, Methods, Models & Applications details the new theory about the method. The second part, Applications & Performance in Forecasting Competitions, describes empirical results and simulations on the method. The last part roadmaps future research and also include contributions from another leading scholar of the method – Dr. Fotios Petropoulos. First ever book to be published on the Theta Method Explores new theory and exact conditions under which methods would outperform most forecasting benchmarks Clearly written with practical applications Employs R – open source code with all included implementations Forecasting with the Theta Method: Theory and Applications is a valuable tool for both academics and practitioners involved in forecasting and respective software development.
Szabó Barna Introduction to Finite Element Analysis. Formulation, Verification and Validation Szabó Barna Introduction to Finite Element Analysis. Formulation, Verification and Validation Новинка

Szabó Barna Introduction to Finite Element Analysis. Formulation, Verification and Validation

9122.14 руб.
When using numerical simulation to make a decision, how can its reliability be determined? What are the common pitfalls and mistakes when assessing the trustworthiness of computed information, and how can they be avoided? Whenever numerical simulation is employed in connection with engineering decision-making, there is an implied expectation of reliability: one cannot base decisions on computed information without believing that information is reliable enough to support those decisions. Using mathematical models to show the reliability of computer-generated information is an essential part of any modelling effort. Giving users of finite element analysis (FEA) software an introduction to verification and validation procedures, this book thoroughly covers the fundamentals of assuring reliability in numerical simulation. The renowned authors systematically guide readers through the basic theory and algorithmic structure of the finite element method, using helpful examples and exercises throughout. Delivers the tools needed to have a working knowledge of the finite element method Illustrates the concepts and procedures of verification and validation Explains the process of conceptualization supported by virtual experimentation Describes the convergence characteristics of the h-, p- and hp-methods Covers the hierarchic view of mathematical models and finite element spaces Uses examples and exercises which illustrate the techniques and procedures of quality assurance Ideal for mechanical and structural engineering students, practicing engineers and applied mathematicians Includes parameter-controlled examples of solved problems in a companion website (www.wiley.com/go/szabo)
Dimiter Dimitrov M. Statistical Methods for Validation of Assessment Scale Data in Counseling and Related Fields Dimiter Dimitrov M. Statistical Methods for Validation of Assessment Scale Data in Counseling and Related Fields Новинка

Dimiter Dimitrov M. Statistical Methods for Validation of Assessment Scale Data in Counseling and Related Fields

5187.75 руб.
“Dr. Dimitrov has constructed a masterpiece—a classic resource that should adorn the shelf of every counseling researcher and graduate student serious about the construction and validation of high quality research instruments. —Bradley T. Erford, PhD Loyola University Maryland Past President, American Counseling Association “This book offers a comprehensive treatment of the statistical models and methods needed to properly examine the psychometric properties of assessment scale data. It is certain to become a definitive reference for both novice and experienced researchers alike.” —George A. Marcoulides, PhD University of California, Riverside This instructive book presents statistical methods and procedures for the validation of assessment scale data used in counseling, psychology, education, and related fields. In Part I, measurement scales, reliability, and the unified construct-based model of validity are discussed, along with key steps in instrument development. Part II describes factor analyses in construct validation, including exploratory factor analysis, confirmatory factor analysis, and models of multitrait-multimethod data analysis. Traditional and Rasch-based analyses of binary and rating scales are examined in Part III. Dr. Dimitrov offers students, researchers, and clinicians step-by-step guidance on contemporary methodological principles, statistical methods, and psychometric procedures that are useful in the development or validation of assessment scale data. Numerous examples, tables, and figures provided throughout the text illustrate the underlying principles of measurement in a clear and concise manner for practical application. *Requests for digital versions from the ACA can be found on wiley.com. *To request print copies, please visit the ACA website.
Peter Blythe Attention, Balance and Coordination. The A.B.C. of Learning Success Peter Blythe Attention, Balance and Coordination. The A.B.C. of Learning Success Новинка

Peter Blythe Attention, Balance and Coordination. The A.B.C. of Learning Success

4179.49 руб.
An updated edition of the definitive handbook on the physical basis for learning for professionals involved in education and child development, written by the respected author of acclaimed titles in the field. A comprehensive overview of the relationship between neuromotor maturity and physical development on learning outcomes and behaviour in childhood and later life Explores why early reflexes are important, their functions in early development, their effects on learning and behavior if retained, and the possible effects on other aspects of development Brings together a specialist body of knowledge and makes it accessible to anyone involved in treating the symptoms of specific learning difficulties and emotional problems. Includes new information on the role of the vestibular system in anxiety and agoraphobia, a new chapter of case studies, and an Epilogue placing the INPP Method in a broader scientific context
Dominique Bonneau Mixed Lubrication in Hydrodynamic Bearings Dominique Bonneau Mixed Lubrication in Hydrodynamic Bearings Новинка

Dominique Bonneau Mixed Lubrication in Hydrodynamic Bearings

8565.23 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book is dedicated to the mixed lubrication.
Dominique Bonneau Hydrodynamic Bearings Dominique Bonneau Hydrodynamic Bearings Новинка

Dominique Bonneau Hydrodynamic Bearings

8565.23 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book describes the rheological models and the equations of lubrication. It also presents the numerical approaches used to solve the above equations by finite differences, finite volumes and finite elements methods.
Marcin Kaminski The Stochastic Perturbation Method for Computational Mechanics Marcin Kaminski The Stochastic Perturbation Method for Computational Mechanics Новинка

Marcin Kaminski The Stochastic Perturbation Method for Computational Mechanics

10753.74 руб.
Probabilistic analysis is increasing in popularity and importance within engineering and the applied sciences. However, the stochastic perturbation technique is a fairly recent development and therefore remains as yet unknown to many students, researchers and engineers. Fields in which the methodology can be applied are widespread, including various branches of engineering, heat transfer and statistical mechanics, reliability assessment and also financial investments or economical prognosis in analytical and computational contexts. Stochastic Perturbation Method in Applied Sciences and Engineering is devoted to the theoretical aspects and computational implementation of the generalized stochastic perturbation technique. It is based on any order Taylor expansions of random variables and enables for determination of up to fourth order probabilistic moments and characteristics of the physical system response. Key features: Provides a grounding in the basic elements of statistics and probability and reliability engineering Describes the Stochastic Finite, Boundary Element and Finite Difference Methods, formulated according to the perturbation method Demonstrates dual computational implementation of the perturbation method with the use of Direct Differentiation Method and the Response Function Method Accompanied by a website (www.wiley.com/go/kaminski) with supporting stochastic numerical software Covers the computational implementation of the homogenization method for periodic composites with random and stochastic material properties Features case studies, numerical examples and practical applications Stochastic Perturbation Method in Applied Sciences and Engineering is a comprehensive reference for researchers and engineers, and is an ideal introduction to the subject for postgraduate and graduate students.
Young Daniel L. Systems Biology in Drug Discovery and Development Young Daniel L. Systems Biology in Drug Discovery and Development Новинка

Young Daniel L. Systems Biology in Drug Discovery and Development

9418.79 руб.
The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent that integration, inform the drug research processes that are most relevant to the pharmaceutical and biotechnology industries. The first book to focus on comprehensive systems biology and its applications in drug discovery and development, it offers comprehensive and multidisciplinary coverage of all phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design and execution, as well as the complementary systems approaches that make these processes more efficient. It also provides models for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker identification. Introducing and explaining key methods and technical approaches to the use of comprehensive systems biology on drug development, the book addresses the challenges currently facing the pharmaceutical industry. As a result, it is essential reading for pharmaceutical and biotech scientists, pharmacologists, computational modelers, bioinformaticians, and graduate students in systems biology, pharmaceutical science, and other related fields.
Dominique Bonneau Internal Combustion Engine Bearings Lubrication in Hydrodynamic Bearings Dominique Bonneau Internal Combustion Engine Bearings Lubrication in Hydrodynamic Bearings Новинка

Dominique Bonneau Internal Combustion Engine Bearings Lubrication in Hydrodynamic Bearings

10077.23 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book with the specific case of internal combustion engine (ICE) journal bearing lubrication. Many examples, relating to various types of ICE, are presented.
Gerhard Girmscheid Bauprozesse und Bauverfahren des Tunnelbaus Gerhard Girmscheid Bauprozesse und Bauverfahren des Tunnelbaus Новинка

Gerhard Girmscheid Bauprozesse und Bauverfahren des Tunnelbaus

10325.81 руб.
The successful completion of a tunnelling project depends on the choice of a construction method and the operational development. In this book, tunnelling methods and all the operational working steps are explained, starting from the geological situation.
Satinder Ahuja Chiral Separation Methods for Pharmaceutical and Biotechnological Products Satinder Ahuja Chiral Separation Methods for Pharmaceutical and Biotechnological Products Новинка

Satinder Ahuja Chiral Separation Methods for Pharmaceutical and Biotechnological Products

11717.87 руб.
Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
R. Sugirtharajah S. Exploring Postcolonial Biblical Criticism. History, Method, Practice R. Sugirtharajah S. Exploring Postcolonial Biblical Criticism. History, Method, Practice Новинка

R. Sugirtharajah S. Exploring Postcolonial Biblical Criticism. History, Method, Practice

7486.83 руб.
Exploring Postcolonial Biblical Criticism: History, Method, Practice offers a concise and multifaceted overview of the origins, development, and application of postcolonial criticism to biblical studies.? Offers a concise and accessible introduction to postcolonial biblical studies Provides a comprehensive overview of postcolonial studies by one of the field's most prominent figures Explains one of the most innovative and important developments in modern biblical studies Accessible enough to appeal to general readers interested in religion
Pierre Saguet Numerical Analysis in Electromagnetics. The TLM Method Pierre Saguet Numerical Analysis in Electromagnetics. The TLM Method Новинка

Pierre Saguet Numerical Analysis in Electromagnetics. The TLM Method

7709.32 руб.
The aim of this book is to give a broad overview of the TLM (Transmission Line Matrix) method, which is one of the “time-domain numerical methods”. These methods are reputed for their significant reliance on computer resources. However, they have the advantage of being highly general. The TLM method has acquired a reputation for being a powerful and effective tool by numerous teams and still benefits today from significant theoretical developments. In particular, in recent years, its ability to simulate various situations with excellent precision, including complex materials, has been demonstrated. Application examples are included in the last two chapters of the book, enabling the reader to draw conclusions regarding the performance of the implemented techniques and, at the same time, to validate them. Contents 1. Basis of the TLM Method: the 2D TLM Method. 2. 3D Nodes. 3. Introduction of Discrete Elements and Thin Wires in the TLM Method. 4. The TLM Method in Matrix Form and the Z Transform. Appendix A. Development of Maxwell’s Equations using the Z Transform with a Variable Mesh. Appendix B. Treatment of Plasma using the Z Transform for the TLM Method.
Claudio Carini Biomarkers in Drug Development. A Handbook of Practice, Application, and Strategy Claudio Carini Biomarkers in Drug Development. A Handbook of Practice, Application, and Strategy Новинка

Claudio Carini Biomarkers in Drug Development. A Handbook of Practice, Application, and Strategy

14684.23 руб.
Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers have emerged as a valuable tool. This book synthesizes and reviews the latest efforts to identify, develop, and integrate biomarkers as a key strategy in translational medicine and the drug development process. Filled with case studies, the book demonstrates how biomarkers can improve drug development timelines, lower costs, facilitate better compound selection, reduce late-stage attrition, and open the door to personalized medicine. Biomarkers in Drug Development is divided into eight parts: Part One offers an overview of biomarkers and their role in drug development. Part Two highlights important technologies to help researchers identify new biomarkers. Part Three examines the characterization and validation process for both drugs and diagnostics, and provides practical advice on appropriate statistical methods to ensure that biomarkers fulfill their intended purpose. Parts Four through Six examine the application of biomarkers in discovery, preclinical safety assessment, clinical trials, and translational medicine. Part Seven focuses on lessons learned and the practical aspects of implementing biomarkers in drug development programs. Part Eight explores future trends and issues, including data integration, personalized medicine, and ethical concerns. Each of the thirty-eight chapters was contributed by one or more leading experts, including scientists from biotechnology and pharmaceutical firms, academia, and the U.S. Food and Drug Administration. Their contributions offer pharmaceutical and clinical researchers the most up-to-date understanding of the strategies used for and applications of biomarkers in drug development.
Chongmin Song The Scaled Boundary Finite Element Method. Introduction to Theory and Implementation Chongmin Song The Scaled Boundary Finite Element Method. Introduction to Theory and Implementation Новинка

Chongmin Song The Scaled Boundary Finite Element Method. Introduction to Theory and Implementation

8652.43 руб.
An informative look at the theory, computer implementation, and application of the scaled boundary finite element method This reliable resource, complete with MATLAB, is an easy-to-understand introduction to the fundamental principles of the scaled boundary finite element method. It establishes the theory of the scaled boundary finite element method systematically as a general numerical procedure, providing the reader with a sound knowledge to expand the applications of this method to a broader scope. The book also presents the applications of the scaled boundary finite element to illustrate its salient features and potentials. The Scaled Boundary Finite Element Method: Introduction to Theory and Implementation covers the static and dynamic stress analysis of solids in two and three dimensions. The relevant concepts, theory and modelling issues of the scaled boundary finite element method are discussed and the unique features of the method are highlighted. The applications in computational fracture mechanics are detailed with numerical examples. A unified mesh generation procedure based on quadtree/octree algorithm is described. It also presents examples of fully automatic stress analysis of geometric models in NURBS, STL and digital images. Written in lucid and easy to understand language by the co-inventor of the scaled boundary element method Provides MATLAB as an integral part of the book with the code cross-referenced in the text and the use of the code illustrated by examples Presents new developments in the scaled boundary finite element method with illustrative examples so that readers can appreciate the significant features and potentials of this novel method—especially in emerging technologies such as 3D printing, virtual reality, and digital image-based analysis The Scaled Boundary Finite Element Method: Introduction to Theory and Implementation is an ideal book for researchers, software developers, numerical analysts, and postgraduate students in many fields of engineering and science.
Wolfram Weckwerth Metabolomics in Practice. Successful Strategies to Generate and Analyze Metabolic Data Wolfram Weckwerth Metabolomics in Practice. Successful Strategies to Generate and Analyze Metabolic Data Новинка

Wolfram Weckwerth Metabolomics in Practice. Successful Strategies to Generate and Analyze Metabolic Data

9358.11 руб.
Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the insight and advice offered here helps to clear the hurdles in setting up and running a successful analysis, resulting in high-quality data from every experiment. Based on more than a decade of practical experience in developing, optimizing and validating metabolomics approaches as a routine technology in the academic and industrial research laboratory, the lessons taught here are highly relevant for all systems-level approaches, whether in systems biology, biotechnology, toxicology or pharmaceutical sciences. From the Contents: * Sampling and Sample Preparation in Microbial Metabolomics * Tandem Mass Spectrometry Hyphenated with HPLC and UHPLC for Targeted Metabolomics * GC-MS, LC-MS, CE-MS and Ultrahigh Resolution MS (FTICR-MS) in Metabolomics * NMR-based metabolomics analysis * Potential of Microfluidics and Single Cell Analysis in Metabolomics * Data Processing in Metabolomics * Validation and Measurement Uncertainty in Metabolomic Studies * Metabolomics and its Role in the Study of Mammalian Systems and in Plant Sciences * Metabolomics in Biotechnology and Nutritional Metabolomics and more.
Mrityunjay Singh Design, Development, and Applications of Engineering Ceramics and Composites Mrityunjay Singh Design, Development, and Applications of Engineering Ceramics and Composites Новинка

Mrityunjay Singh Design, Development, and Applications of Engineering Ceramics and Composites

8781.72 руб.
This compilation of proceedings covering the latest scientific and technological developments in design, development, and applications of engineering ceramics and composites provides a useful one-stop resource for understanding the most important issues in design, development, and applications of engineering ceramics and composites. Logically organized and carefully selected articles give insight into design, development, and applications of engineering ceramics and composites and incorporates the latest developments related to design, development, and applications of engineering ceramics and composites including developments in engineering ceramics, advanced ceramic coatings, and geopolymers.
Nicolas Larrieu Rapid Prototyping Software for Avionics Systems. Model-oriented Approaches for Complex Systems Certification Nicolas Larrieu Rapid Prototyping Software for Avionics Systems. Model-oriented Approaches for Complex Systems Certification Новинка

Nicolas Larrieu Rapid Prototyping Software for Avionics Systems. Model-oriented Approaches for Complex Systems Certification

7050.51 руб.
The design, implementation and validation of avionics and aeronautical systems have become extremely complex tasks due to the increase of functionalities that are deployed in current avionics systems and the need to be able certify them before putting them into production. This book proposes a methodology to enable the rapid prototyping of such a system by considering from the start the certification aspects of the solution produced. This method takes advantage of the model-based design approaches as well as the use of formal methods for the validation of these systems. Furthermore, the use of automatic software code generation tools using models makes it possible to reduce the development phase as well as the final solution testing. This book presents, firstly, an overview of the model-based design approaches such as those used in the field of aeronautical software engineering. Secondly, an original methodology that is perfectly adapted to the field of aeronautical embedded systems is introduced. Finally, the authors illustrate the use of this method using a case study for the design, implementation and testing of a new generation aeronautical router.
Richard Lerner M. Handbook of Child Psychology and Developmental Science, Theory and Method Richard Lerner M. Handbook of Child Psychology and Developmental Science, Theory and Method Новинка

Richard Lerner M. Handbook of Child Psychology and Developmental Science, Theory and Method

16555.44 руб.
The essential reference for human development theory, updated and reconceptualized The Handbook of Child Psychology and Developmental Science, a four-volume reference, is the field-defining work to which all others are compared. First published in 1946, and now in its Seventh Edition, the Handbook has long been considered the definitive guide to the field of developmental science. Volume 1, Theory and Method, presents a rich mix of classic and contemporary theoretical perspectives, but the dominant views throughout are marked by an emphasis on the dynamic interplay of all facets of the developmental system across the life span, incorporating the range of biological, cognitive, emotional, social, cultural, and ecological levels of analysis. Examples of the theoretical approaches discussed in the volume include those pertinent to human evolution, self regulation, the development of dynamic skills, and positive youth development. The research, methodological, and applied implications of the theoretical models discussed in the volume are presented. Understand the contributions of biology, person, and context to development within the embodied ecological system Discover the relations among individual, the social world, culture, and history that constitute human development Examine the methods of dynamic, developmental research Learn person-oriented methodological approaches to assessing developmental change The scholarship within this volume and, as well, across the four volumes of this edition, illustrate that developmental science is in the midst of a very exciting period. There is a paradigm shift that involves increasingly greater understanding of how to describe, explain, and optimize the course of human life for diverse individuals living within diverse contexts. This Handbook is the definitive reference for educators, policy-makers, researchers, students, and practitioners in human development, psychology, sociology, anthropology, and neuroscience.
Clinton Padgett M. The Project Success Method. A Proven Approach for Achieving Superior Project Performance in as Little as 5 Days Clinton Padgett M. The Project Success Method. A Proven Approach for Achieving Superior Project Performance in as Little as 5 Days Новинка

Clinton Padgett M. The Project Success Method. A Proven Approach for Achieving Superior Project Performance in as Little as 5 Days

1851.94 руб.
The Project Success Method is a unique, proven and fire-tested methodology which allows companies, groups or managers to learn and develop consistency in the way they plan, schedule, manage, control and close out projects on time, per spec and within budget– in as little as 5 days. Over the last 25 years, the methodology has been used around the world by manufacturers of heavy equipment, electronics, aircraft components, paper products, beverages, electric and gas utilities, hotel and restaurant chains, and companies in the financial services, telecommunications, real estate, entertainment, and transportation industries. The Project Success Method has proven effective in a vast array of project applications, including new product development and introduction, IT systems development and implementation, process improvement initiatives, marketing programs, engineering and architectural design, construction and renovation, facility relocations and startups, mergers and acquisitions, major industrial maintenance and special events.
William J. Rothwell Practicing Organization Development. Leading Transformation and Change William J. Rothwell Practicing Organization Development. Leading Transformation and Change Новинка

William J. Rothwell Practicing Organization Development. Leading Transformation and Change

6838.12 руб.
Get on the cutting edge of organization development Practicing Organization Development: Leading Transformation and Change, Fourth Edition is your newly revised guide to successful organization development. This edition has been updated to explore the cutting edge of change management, leadership development, organizational transformation, and society benefit. These concepts are explored through emerging and increasingly accepted strengths-based approaches such as: appreciative inquiry, emotionally and socially intelligent leadership, positive organization development, and sustainable enterprises. This edition offers both theoretical concepts and guides to practical applications, providing you with the knowledge, techniques, and tools to put organizational development to effective use in the workplace. Organization development is an evolving field focused on understanding and positively impacting the human system processes of groups, teams, organizations, and individual leaders. Thorough organization development results in increased effectiveness, improved health, and overall success. This book shows how to attain positive change by: identifying contemporary themes in organization development, executing organization development approaches, as well as elevating and extending research agenda. This book also illustrates how to influence organizational stakeholders, and how to use this influence to enact key organization development practices. This new edition is enhanced by: Updated chapter-by-chapter lesson plans, sample syllabi, and workshop agendas Revised sample exercises, a test bank, and additional case studies Expanded online appendices that cover regional organization development concepts from around the globe, as well as overviews of additional special issues Organization development is quickly becoming an important aspect of MBA curricula. Practicing Organization Development: Leading Transformation and Change, Fourth Edition gives graduate and doctorate program participants a comprehensive overview of organization development, the resources to learn the field, and the tools to apply their knowledge.
Guomin Shan Immunoassays in Agricultural Biotechnology Guomin Shan Immunoassays in Agricultural Biotechnology Новинка

Guomin Shan Immunoassays in Agricultural Biotechnology

10902.07 руб.
A very broad range of professionals are using immunoassay technology daily to analyze genetically engineered (GE) crops and related areas, and many of these professionals are completely new to this technology. There is a great need for users to have a book containing technical and practical guidance, and describing limitations and pitfalls of applying immunoassay in agricultural biotechnology. This book focuses on the application of immunoassays to GE plants and related areas. A group of international experts from government agencies, academics and industries, who have many years of related experience, contribute high quality chapters in their areas of expertise. This book covers topics including principles of immunoassay, antibody engineering in AgBiotech, current technologies (formats, kit development, manufacturing and quality control), method validation, applications in trait discovery and product development, applications in grain products and food processing, applications in environmental monitoring, automation and high throughput, reference materials, data interpretation and source of error, and future perspectives and challenges. In addition, to meet the practical needs for a variety of readers from different backgrounds, methods and protocols are included as well.
Robert Rasmussen Building a Better Business Using the Lego Serious Play Method Robert Rasmussen Building a Better Business Using the Lego Serious Play Method Новинка

Robert Rasmussen Building a Better Business Using the Lego Serious Play Method

1670.09 руб.
Unleash innovation potential with creative, serious play Building a Better Business Using the LEGO® SERIOUS PLAY® Method delivers a creative approach to enhancing innovation and improving business performance, with the focus on unleashing play. Written by the two original Master Trainers for LEGO SERIOUS PLAY (LSP), the book outlines how LSP can develop teams, people, relationships and business . Based on the merging of play with organizational development, systems thinking and strategy development, LSP can foster improved meetings, faster innovation processes, team growth, and better communication. The belief that everyone intends to «do good» and has the potential to do it is at the heart of LSP. The method nurtures the idea that everyone in an organization can contribute to discussions and outcomes. Building with LEGO bricks is a type of creative play that triggers a different kind of thought process, unleashing imagination and potential that is frequently untapped by the logical mind. The book explains this hands-on, minds-on approach, and discusses the theory as well as the practical implementation of LSP. Topics include: Observation of internal and external interaction dynamics Fostering a free and honest exchange of opinions Suspending hierarchy for better, more effective communication Facilitating change by encouraging exploration The LEGO SERIOUS PLAY method is employed by start-ups and multinational corporations alike to maximize synergy among teams and throughout organizations. For leaders looking to boost effectiveness and see better results, Building a Better Business Using the LEGO® SERIOUS PLAY® Method is a comprehensive introduction to this creative management technique.
Elaine Biech Training and Development For Dummies Elaine Biech Training and Development For Dummies Новинка

Elaine Biech Training and Development For Dummies

1669.47 руб.
Develop and deliver a robust employee training and development program Training and Development For Dummies gives you the tools you need to develop a strong and effective training and development program. Covering the latest in talent development, this informative guide addresses classroom, virtual, and blended learning to open up your options and help you design the program that's right for your company. You'll explore the different modes of formal learning, including social learning, m-learning, and MOOCs, and delve into the benefits and implementation of self-directed and informal learning. The discussion covers mentoring and coaching, rotational and stretch assignments, and how to align talent development with the company's needs. You'll learn how to assess employee skills, design and deliver training, and evaluate each step of the process to achieve the goals of both the employee and the organization. Most employees have some weaknesses in their skill sets. A robust training program allows you to strengthen those skills, and a development program brings all employees up to the highest possible level of productivity and success. This book helps you create consistency in your company by developing and delivering the exact training and development program your people need. Develop a strong training and development program Foster a supportive and innovative work environment Learn about social learning, m-learning, and MOOCs Assess and evaluate your staff more effectively A great training and development program boosts performance, productivity, job satisfaction, and quality of services, while reducing costs and supervision. Investing in your employees gives an excellent ROI, as talent development is a primary driver behind both motivation and loyalty. Training and Development For Dummies shows you how to reap these benefits, with step by step guidance and essential expert insight.
Mourad Oussalah Chabane Software Architecture 1 Mourad Oussalah Chabane Software Architecture 1 Новинка

Mourad Oussalah Chabane Software Architecture 1

8380.5 руб.
Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural templates and styles, their formalization, validation and testing and finally the engineering approach in which these consistent and autonomous elements can be tackled.
Mourad Oussalah Chabane Software Architecture 2 Mourad Oussalah Chabane Software Architecture 2 Новинка

Mourad Oussalah Chabane Software Architecture 2

8083.85 руб.
Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural templates and styles, their formalization, validation and testing and finally the engineering approach in which these consistent and autonomous elements can be tackled.
Stavros Kromidas The HPLC-MS Handbook for Practitioners Stavros Kromidas The HPLC-MS Handbook for Practitioners Новинка

Stavros Kromidas The HPLC-MS Handbook for Practitioners

7917.82 руб.
Filling the gap for an expert text dealing exclusively with the practical aspects of HPLC-MS coupling, this concise, compact, and clear book provides detailed information to enable users to employ the method most efficiently. Following an overview of the current state of HPLC-MS and its instrumentation, the text goes on to discuss all relevant aspects of method development. A chapter on tips and tricks is followed by user reports on the advantages – and pitfalls – of applying the method in real-life scenarios. The whole is rounded off by a look at future developments by renowned manufacturers.
Perumal Nithiarasu Fundamentals of the Finite Element Method for Heat and Mass Transfer Perumal Nithiarasu Fundamentals of the Finite Element Method for Heat and Mass Transfer Новинка

Perumal Nithiarasu Fundamentals of the Finite Element Method for Heat and Mass Transfer

7558.6 руб.
Fundamentals of the Finite Element Method for Heat and Mass Transfer, Second Edition is a comprehensively updated new edition and is a unique book on the application of the finite element method to heat and mass transfer. • Addresses fundamentals, applications and computer implementation • Educational computer codes are freely available to download, modify and use • Includes a large number of worked examples and exercises • Fills the gap between learning and research
Charles Wasson S. System Engineering Analysis, Design, and Development. Concepts, Principles, and Practices Charles Wasson S. System Engineering Analysis, Design, and Development. Concepts, Principles, and Practices Новинка

Charles Wasson S. System Engineering Analysis, Design, and Development. Concepts, Principles, and Practices

9718.01 руб.
Praise for the first edition: “This excellent text will be useful to every system engineer (SE) regardless of the domain. It covers ALL relevant SE material and does so in a very clear, methodical fashion. The breadth and depth of the author's presentation of SE principles and practices is outstanding.” –Philip Allen This textbook presents a comprehensive, step-by-step guide to System Engineering analysis, design, and development via an integrated set of concepts, principles, practices, and methodologies. The methods presented in this text apply to any type of human system – small, medium, and large organizational systems and system development projects delivering engineered systems or services across multiple business sectors such as medical, transportation, financial, educational, governmental, aerospace and defense, utilities, political, and charity, among others. Provides a common focal point for “bridging the gap” between and unifying System Users, System Acquirers, multi-discipline System Engineering, and Project, Functional, and Executive Management education, knowledge, and decision-making for developing systems, products, or services Each chapter provides definitions of key terms, guiding principles, examples, author’s notes, real-world examples, and exercises, which highlight and reinforce key SE&D concepts and practices Addresses concepts employed in Model-Based Systems Engineering (MBSE), Model-Driven Design (MDD), Unified Modeling Language (UMLTM) / Systems Modeling Language (SysMLTM), and Agile/Spiral/V-Model Development such as user needs, stories, and use cases analysis; specification development; system architecture development; User-Centric System Design (UCSD); interface definition & control; system integration & test; and Verification & Validation (V&V) Highlights/introduces a new 21st Century Systems Engineering & Development (SE&D) paradigm that is easy to understand and implement. Provides practices that are critical staging points for technical decision making such as Technical Strategy Development; Life Cycle requirements; Phases, Modes, & States; SE Process; Requirements Derivation; System Architecture Development, User-Centric System Design (UCSD); Engineering Standards, Coordinate Systems, and Conventions; et al. Thoroughly illustrated, with end-of-chapter exercises and numerous case studies and examples, Systems Engineering Analysis, Design, and Development, Second Edition is a primary textbook for multi-discipline, engineering, system analysis, and project management undergraduate/graduate level students and a valuable reference for professionals.
Nicolae-Doru Stanescu Classical and Modern Approaches in the Theory of Mechanisms Nicolae-Doru Stanescu Classical and Modern Approaches in the Theory of Mechanisms Новинка

Nicolae-Doru Stanescu Classical and Modern Approaches in the Theory of Mechanisms

8604.84 руб.
Classical and Modern Approaches in the Theory of Mechanisms is a study of mechanisms in the broadest sense, covering the theoretical background of mechanisms, their structures and components, the planar and spatial analysis of mechanisms, motion transmission, and technical approaches to kinematics, mechanical systems, and machine dynamics. In addition to classical approaches, the book presents two new methods: the analytic-assisted method using Turbo Pascal calculation programs, and the graphic-assisted method, outlining the steps required for the development of graphic constructions using AutoCAD; the applications of these methods are illustrated with examples. Aimed at students of mechanical engineering, and engineers designing and developing mechanisms in their own fields, this book provides a useful overview of classical theories, and modern approaches to the practical and creative application of mechanisms, in seeking solutions to increasingly complex problems.
Michael Brazzel The NTL Handbook of Organization Development and Change. Principles, Practices, and Perspectives Michael Brazzel The NTL Handbook of Organization Development and Change. Principles, Practices, and Perspectives Новинка

Michael Brazzel The NTL Handbook of Organization Development and Change. Principles, Practices, and Perspectives

9789.72 руб.
The NTL Handbook of Organization Development and Change, Second Edition The NTL Handbook of Organization Development and Change is a vital tool for anyone who wants to know how to effectively bring about meaningful and sustainable change in organizations—even in the state of turbulence and complexity that today’s organizations encounter. Featuring contributions from leading practitioners and scholars in the field, each chapter explores a key aspect of organization development. In this new edition, each of the 34 chapters has been revised in response to recommendations from the contributors and NTL members. “These 34 chapters articulate exactly what grounds organization development! Issues and perspectives involving training, groups, practice, and the global world are current and thought provoking.” —Therese F. Yaeger Ph.D., professor, OB/OD Department, College of Business, Benedictine University “There is no other source that offers such a rich array of the most current and future-thinking topics from so many leaders in the field.” —Robert Gass, Ed.D., co-founder, Rockwood Leadership Institute “The editors accomplish the difficult task of including theory, concept, and method that will appeal to the academic community as well as those who are focused on being an effective practitioner.” —John D. Carter, Ph.D., president, Gestalt OSD Center
Jocelyn Berard Accelerating Leadership Development. Practical Solutions for Building Your Organization's Potential Jocelyn Berard Accelerating Leadership Development. Practical Solutions for Building Your Organization's Potential Новинка

Jocelyn Berard Accelerating Leadership Development. Practical Solutions for Building Your Organization's Potential

2283.62 руб.
Proven strategies and innovative solutions for developing and retaining successful leaders Many organizations today are facing a crisis of leadership. As the Baby Boomer generation exits the workforce, companies are struggling to find qualified leaders to fill critical roles. Accelerating Leadership Development offers solutions for leadership development, management, and retention from award-winning development firm Global Knowledge. Accelerating Leadership Development provides a proven model to help companies develop high-potential employees with the competencies and knowledge capital to assume critical roles successfully. It includes practical and rigorous tools that enable organizations to identify targets and predict those targets' success with six measurable factors. With this proven development system, companies can develop a pipeline of ready leaders with high levels of engagement and retention. Features actionable, effective principles and strategies for leadership development using a results-oriented framework Chapters address communication and delegation strategies, effective feedback models, shifting of responsibility and accountability to direct reports, and contemporary coaching and development approaches Based on in-depth research and client interactions from one of the most prominent names in workforce development For any business that experiences a leadership failure or a lack of qualified leaders for vital positions, the consequences can be devastating. This practical and effective guide to leadership development offers real solutions for long-term excellence.
Dirk Kroese P. Simulation and the Monte Carlo Method Dirk Kroese P. Simulation and the Monte Carlo Method Новинка

Dirk Kroese P. Simulation and the Monte Carlo Method

9358.11 руб.
This accessible new edition explores the major topics in Monte Carlo simulation that have arisen over the past 30 years and presents a sound foundation for problem solving Simulation and the Monte Carlo Method, Third Edition reflects the latest developments in the field and presents a fully updated and comprehensive account of the state-of-the-art theory, methods and applications that have emerged in Monte Carlo simulation since the publication of the classic First Edition over more than a quarter of a century ago. While maintaining its accessible and intuitive approach, this revised edition features a wealth of up-to-date information that facilitates a deeper understanding of problem solving across a wide array of subject areas, such as engineering, statistics, computer science, mathematics, and the physical and life sciences. The book begins with a modernized introduction that addresses the basic concepts of probability, Markov processes, and convex optimization. Subsequent chapters discuss the dramatic changes that have occurred in the field of the Monte Carlo method, with coverage of many modern topics including: Markov Chain Monte Carlo, variance reduction techniques such as importance (re-)sampling, and the transform likelihood ratio method, the score function method for sensitivity analysis, the stochastic approximation method and the stochastic counter-part method for Monte Carlo optimization, the cross-entropy method for rare events estimation and combinatorial optimization, and application of Monte Carlo techniques for counting problems. An extensive range of exercises is provided at the end of each chapter, as well as a generous sampling of applied examples. The Third Edition features a new chapter on the highly versatile splitting method, with applications to rare-event estimation, counting, sampling, and optimization. A second new chapter introduces the stochastic enumeration method, which is a new fast sequential Monte Carlo method for tree search. In addition, the Third Edition features new material on: • Random number generation, including multiple-recursive generators and the Mersenne Twister • Simulation of Gaussian processes, Brownian motion, and diffusion processes • Multilevel Monte Carlo method • New enhancements of the cross-entropy (CE) method, including the “improved” CE method, which uses sampling from the zero-variance distribution to find the optimal importance sampling parameters • Over 100 algorithms in modern pseudo code with flow control • Over 25 new exercises Simulation and the Monte Carlo Method, Third Edition is an excellent text for upper-undergraduate and beginning graduate courses in stochastic simulation and Monte Carlo techniques. The book also serves as a valuable reference for professionals who would like to achieve a more formal understanding of the Monte Carlo method. Reuven Y. Rubinstein, DSc, was Professor Emeritus in the Faculty of Industrial Engineering and Management at Technion-Israel Institute of Technology. He served as a consultant at numerous large-scale organizations, such as IBM, Motorola, and NEC. The author of over 100 articles and six books, Dr. Rubinstein was also the inventor of the popular score-function method in simulation analysis and generic cross-entropy methods for combinatorial optimization and counting. Dirk P. Kroese, PhD, is a Professor of Mathematics and Statistics in the School of Mathematics and Physics of The University of Queensland, Australia. He has published over 100 articles and four books in a wide range of areas in applied probability and statistics, including Monte Carlo methods, cross-entropy, randomized algorithms, tele-traffic c theory, reliability, computational statistics, applied probability, and stochastic modeling.
Ming-Li Shiu Quality Strategy for Research and Development Ming-Li Shiu Quality Strategy for Research and Development Новинка

Ming-Li Shiu Quality Strategy for Research and Development

8494.21 руб.
Provides a clear, useful framework and methods for R&D, including robust technology development, product planning, and product design and development management Quality Strategy for Research and Development integrates the Japanese and Western perspectives on Quality Function Deployment (QFD), updates the strategy of Robust Engineering (RE), and relates their unique frameworks to current, widely adopted philosophies of quality assurance. Featuring real-world case studies, more than thirty tables, and over seventy figures, this essential guide identifies key issues and proposes improvements in the current R&D paradigm. It offers in-depth coverage of technology development, product planning, and product design and development management. Quality Strategy for Research and Development: Updates the conventional approaches to QFD and RE, and provides the implementation model of combining them into a corporate operating system Identifies key issues in the current practice of R&D, and provides solutions for improving design quality and R&D productivity Includes the case studies of designing a functional circuit, magnetic component, measurement system, and machining equipment Offers the integration models of QFD and other breakthrough strategies including DFX (Design For eXcellence), DFSS (Design For Six Sigma), and Blue Ocean Strategy Written for R&D executives, managers, engineers, and quality practitioners, Quality Strategy for Research and Development is also an ideal text for professors and students of industrial and systems engineering, technology management, and business administration.
J. Mahan Robert The Monte Carlo Ray-Trace Method in Radiation Heat Transfer and Applied Optics J. Mahan Robert The Monte Carlo Ray-Trace Method in Radiation Heat Transfer and Applied Optics Новинка

J. Mahan Robert The Monte Carlo Ray-Trace Method in Radiation Heat Transfer and Applied Optics

12459.5 руб.
A groundbreaking guide dedicated exclusively to the MCRT method in radiation heat transfer and applied optics The Monte Carlo Ray-Trace Method in Radiation Heat Transfer and Applied Optics offers the most modern and up-to-date approach to radiation heat transfer modelling and performance evaluation of optical instruments. The Monte Carlo ray-trace (MCRT) method is based on the statistically predictable behavior of entities, called rays, which describe the paths followed by energy bundles as they are emitted, reflected, scattered, refracted, diffracted and ultimately absorbed. The author – a noted expert on the subject – covers a wide variety of topics including the mathematics and statistics of ray tracing, the physics of thermal radiation, basic principles of geometrical and physical optics, radiant heat exchange among surfaces and within participating media, and the statistical evaluation of uncertainty of results obtained using the method. The book is a guide to help formulate and solve models that accurately describe the distribution of radiant energy in thermal and optical systems of practical engineering interest. This important guide: Combines radiation heat transfer and applied optics into a single discipline Covers the MCRT method, which has emerged as the dominant tool for radiation heat transfer modelling Helps readers to formulate and solve models that describe the distribution of radiant energy Features pages of color images and a wealth of line drawings Written for faculty and graduate students in mechanical and aerospace engineering and applied optics professionals, The Monte Carlo Ray-Trace Method in Radiation Heat Transfer and Applied Optics is the first book dedicated exclusively to the MCRT method.
Jian Wang Chemical Analysis of Antibiotic Residues in Food Jian Wang Chemical Analysis of Antibiotic Residues in Food Новинка

Jian Wang Chemical Analysis of Antibiotic Residues in Food

9141.62 руб.
An insightful exploration of the key aspects concerning the chemical analysis of antibiotic residues in food The presence of excess residues from frequent antibiotic use in animals is not only illegal, but can pose serious health risks by contaminating products for human consumption such as meat and milk. Chemical Analysis of Antibiotic Residues in Food is a single-source reference for readers interested in the development of analytical methods for analyzing antibiotic residues in food. It covers themes that include quality assurance and quality control, antibiotic chemical properties, pharmacokinetics, metabolism, distribution, food safety regulations, and chemical analysis. In addition, the material presented includes background information valuable for understanding the choice of marker residue and target animal tissue to use for regulatory analysis. This comprehensive reference: Includes topics on general issues related to screening and confirmatory methods Presents updated information on food safety regulation based on routine screening and confirmatory methods, especially LC-MS Provides general guidance for method development, validation, and estimation of measurement uncertainty Chemical Analysis of Antibiotic Residues in Food is written and organized with a balance between practical use and theory to provide laboratories with a solid and reliable reference on antibiotic residue analysis. Thorough coverage elicits the latest scientific findings to assist the ongoing efforts toward refining analytical methods for producing safe foods of animal origin.
Heather Carpenter The Talent Development Platform. Putting People First in Social Change Organizations Heather Carpenter The Talent Development Platform. Putting People First in Social Change Organizations Новинка

Heather Carpenter The Talent Development Platform. Putting People First in Social Change Organizations

3527.3 руб.
Putting People First in Social Change Organizations The Talent Development Platform is about results driven talent development for social change. Written by seasoned nonprofit experts, this book provides a holistic process for creating an in-house training and talent development program. The Talent Development Platform offers organizations the tools for ensuring their professional development systems are successful through regular feedback loops, tailored for learning styles, and specific to their organization. Detailed case studies provide insight into the strategies used by organizations that have implemented the Talent Development Platform, and interviews with experts in the field give readers a handle on the most current thinking. Robust resource guides facilitate the talent development process, and online access to the Talent Development Platform and assessments help streamline the workflow. Social change organizations make the most of limited resources, but often overlook developing the talent they already have. This book gives readers a plan for finding and nurturing their internal talent to reduce turnover and improve organizational efficiency. More specifically the book helps organizations: Develop organizational, department, and position specific competencies. Create and revise job descriptions. Assess staff and volunteer proficiency levels with created competencies. Determine staff and volunteer learning styles. Establish professional development goals and objectives tied to strategic goals. Implement professional development with on the job learning, mentoring, and training. Calculate a return on talent investment. Evaluate talent development implementation and proficiency level changes. Implementing the Talent Development Platform provides organizations with tangible benefits in the form of lower turnover and greater output (without the burnout) from employees and volunteers, as well as intangible benefits that make organizations more attractive to top talent.
S. P. Peca Real Estate Development and Investment. A Comprehensive Approach S. P. Peca Real Estate Development and Investment. A Comprehensive Approach Новинка

S. P. Peca Real Estate Development and Investment. A Comprehensive Approach

7416.37 руб.
Real Estate Development and Investment A Comprehensive Approach Written by real estate industry veteran Stephen Peca, this timely guide skillfully outlines the various phases of the real estate development process and addresses some of the most important issues associated with this discipline. Using numerous illustrations and anecdotes, this book takes you through the development process, from historical considerations and idea formulation to financial feasibility and asset disposition, while covering the entire cycle of real estate development for various property types. Topics touched upon throughout these pages include: The key factors affecting demand for different land uses and development The interaction of market research, financing, planning, contract negotiation, marketing, leasing, and property management The need for universal, current, and broad knowledge The importance of ethics in the development process The role of different professionals and companies involved in the development process Environmental considerations in real estate development And much more Filled with in-depth insights and practical advice, this reliable resource will help you gain a firm understanding of the functional skills necessary to be successful in this field and familiarize you with several often-overlooked-but essential aspects of commercial real estate development.
Ulrich Mueller Handbook of Child Psychology and Developmental Science, Cognitive Processes Ulrich Mueller Handbook of Child Psychology and Developmental Science, Cognitive Processes Новинка

Ulrich Mueller Handbook of Child Psychology and Developmental Science, Cognitive Processes

16555.44 руб.
The essential reference for human development theory, updated and reconceptualized The Handbook of Child Psychology and Developmental Science, a four-volume reference, is the field-defining work to which all others are compared. First published in 1946, and now in its Seventh Edition, the Handbook has long been considered the definitive guide to the field of developmental science. Volume 2: Cognitive Processes describes cognitive development as a relational phenomenon that can be studied only as part of a larger whole of the person and context relational system that sustains it. In this volume, specific domains of cognitive development are contextualized with respect to biological processes and sociocultural contexts. Furthermore, key themes and issues (e.g., the importance of symbolic systems and social understanding) are threaded across multiple chapters, although every each chapter is focused on a different domain within cognitive development. Thus, both within and across chapters, the complexity and interconnectivity of cognitive development are well illuminated. Learn about the inextricable intertwining of perceptual development, motor development, emotional development, and brain development Understand the complexity of cognitive development without misleading simplification, reducing cognitive development to its biological substrates, or viewing it as a passive socialization process Discover how each portion of the developmental process contributes to subsequent cognitive development Examine the multiple processes – such as categorizing, reasoning, thinking, decision making and judgment – that comprise cognition The scholarship within this volume and, as well, across the four volumes of this edition, illustrate that developmental science is in the midst of a very exciting period. There is a paradigm shift that involves increasingly greater understanding of how to describe, explain, and optimize the course of human life for diverse individuals living within diverse contexts. This Handbook is the definitive reference for educators, policy-makers, researchers, students, and practitioners in human development, psychology, sociology, anthropology, and neuroscience.
Stanley Weiss I. Product and Systems Development. A Value Approach Stanley Weiss I. Product and Systems Development. A Value Approach Новинка

Stanley Weiss I. Product and Systems Development. A Value Approach

7486.83 руб.
A thorough treatment of product and systems development in terms of value to all stakeholders Product and Systems Development compiles more than twenty years of research and practice from a value perspective, from vision and marketing to design, manufacturing, delivery, operations, and maintenance. It defines stakeholder value and identifies specific stakeholders in the product and system development process; covers best practices in development; and examines systems engineering, current industry views, and the life cycle of a value stream. Featuring appendices written by professionals in the field on topics such as Design Structure Matrices, Lean Enablers for systems engineering, and MDAO and simulations, this indispensable guide: Explains why stakeholders' values can hold the key to fulfillment or defeat of the developer's vision Emphasizes the succession of value-contributing practices and tools that form a framework for development success Integrates the technical, productivity, and customer/end-user elements in product and system development Uses more than 100 tables and figures to illustrate the above processes, as well as corollary elements of risk, failure analysis, and fault-tolerant design Includes numerous case studies and links to online material Product and Systems Development is an excellent coursebook for senior and graduate students in aerospace, mechanical, civil, electrical, and material engineering, as well as management science and engineering. It is also a useful reference for practicing engineers in a variety of technology-based industries.
Regenesis Group Regenerative Development and Design. A Framework for Evolving Sustainability Regenesis Group Regenerative Development and Design. A Framework for Evolving Sustainability Новинка

Regenesis Group Regenerative Development and Design. A Framework for Evolving Sustainability

5399.2 руб.
The evolution of sustainability, with a practical framework for integration Regenerative Development and Design takes sustainability to the next level, and provides a framework for incorporating regenerative design principles into your current process. The Regenesis Group is a coalition of experienced design, land-use, planning, business, and development professionals who represent the forefront of the movement; in this book, they explain what regenerative development is, how and why it works, and how you can incorporate the fundamental principles into your practice. A clear, focused framework shows you how to merge regenerative concepts with your existing work, backed by numerous examples that guide practical application while illustrating regenerative design and development in action. As the most comprehensive and systemic approach to regenerative development, this book is a must-have resource for architects, planners, and designers seeking the next step in sustainability. Regenerative design and development positions humans as co-creative and mutually-evolving participants in an ecosystem—not just a built environment. This book describes how to bring that focus to your design from the earliest stages. Understand the fundamentals of regenerative design and development Learn how regenerative development contributes to sustainability Integrate regenerative development concepts into practice Examine sample designs that embody the regenerative concept To create a design with true sustainability, considerations must extend far beyond siting, materials, and efficiency. Designers must look at the place, it's inhabitants, and the purpose—the whole living ecosystem—and proceed with their work from that more humbling perspective. The finished product should itself be an ecosystem and sustainable economy, which is the root of the regenerative development approach. Sustainability has evolved, and the designer's responsibility has increased in kind. Regenerative Development and Design provides an authoritative resource for those ready to take the next step forward.
Tiwari Ashutosh Responsive Materials and Methods. State-of-the-Art Stimuli-Responsive Materials and Their Applications Tiwari Ashutosh Responsive Materials and Methods. State-of-the-Art Stimuli-Responsive Materials and Their Applications Новинка

Tiwari Ashutosh Responsive Materials and Methods. State-of-the-Art Stimuli-Responsive Materials and Their Applications

17725.13 руб.
The development of finely-tuned materials that adjust in a predictable manner by specific environment change is the recent arena of materials research. It is a newly emerging supra-disciplinary field with huge commercial potential. Stimuli-responsive materials answer by a considerable change in their properties to small changes in their environment. Responsive materials are becoming increasingly more prevalent as scientists learn about the chemistry and triggers that induce conformational changes in materials structures and devise ways to take advantage of and control them. Responsive Materials and Method offers state-of-the-art of the stimuli-responsive materials and their potential applications. This collection brings together novel methodologies and strategies adopted in the research and development of responsive materials and technology.
Jean-Louis Leignel Digital Transformation. Information System Governance Jean-Louis Leignel Digital Transformation. Information System Governance Новинка

Jean-Louis Leignel Digital Transformation. Information System Governance

8309.82 руб.
The main aim of this book is to offer companies a simple and practical method to assess their maturity in the Governance Information System, so that they are in working order to face the challenges of Digital Transformation. How can companies effectively manage their investment in IT systems and make the most of their development?
Printio Bdsm (business, development, sales and marketing) Printio Bdsm (business, development, sales and marketing) Новинка

Printio Bdsm (business, development, sales and marketing)

1200 руб.
Рубашка Поло — цвет: БЕЛЫЙ, пол: ЖЕН. BDSM - business, development, sales and marketing - дизайн для тех, кто работает в сфере продаж и имеет хорошее чувство юмора. Только продажи, только хардкор!
Printio Bdsm (business, development, sales and marketing) Printio Bdsm (business, development, sales and marketing) Новинка

Printio Bdsm (business, development, sales and marketing)

1200 руб.
Рубашка Поло — цвет: БЕЛЫЙ, пол: МУЖ. BDSM - business, development, sales and marketing - дизайн для тех, кто работает в сфере продаж и имеет хорошее чувство юмора. Только продажи, только хардкор!
Anatoly Legtchenko Magnetic Resonance Imaging for Groundwater Anatoly Legtchenko Magnetic Resonance Imaging for Groundwater Новинка

Anatoly Legtchenko Magnetic Resonance Imaging for Groundwater

7266.31 руб.
This book presents the basics of the non-invasive geophysical method for groundwater investigation, called Magnetic Resonance Sounding (MRS) or Surface Nuclear Magnetic Resonance (SNMR), and its practical application to the problems of groundwater localization and aquifer characterization. The method is based on the nuclear magnetic resonance (NMR) phenomenon and is selectively sensitive to groundwater. The main aims of the author are to teach the reader the basic principles of the method as well as to formulate consistent approximate models, leading to reasonably simple inverse problems. Containing an extensive bibliography, numerous practical and numerical examples as well as a detailed presentation of the nuts and bolts of the method based on the long-term experience of SNMR development and practical use, this book is useful for students, scientists and professional engineers working in the field of hydrogeophysics and hydrogeology. Contents 1. SNMR Imaging for Groundwater. 2. The Basics of NMR. 3. Forward Modeling. 4. Inversion. 5. Link Between SNMR and Aquifer Parameters.
Yoshihiro Baba Electromagnetic Computation Methods for Lightning Surge Protection Studies Yoshihiro Baba Electromagnetic Computation Methods for Lightning Surge Protection Studies Новинка

Yoshihiro Baba Electromagnetic Computation Methods for Lightning Surge Protection Studies

11517.51 руб.
Presents current research into electromagnetic computation theories with particular emphasis on Finite-Difference Time-Domain Method This book is the first to consolidate current research and to examine the theories of electromagnetic computation methods in relation to lightning surge protection. The authors introduce and compare existing electromagnetic computation methods such as the method of moments (MOM), the partial element equivalent circuit (PEEC), the finite element method (FEM), the transmission-line modeling (TLM) method, and the finite-difference time-domain (FDTD) method. The application of FDTD method to lightning protection studies is a topic that has matured through many practical applications in the past decade, and the authors explain the derivation of Maxwell’s equations required by the FDTD, and modeling of various electrical components needed in computing lightning electromagnetic fields and surges with the FDTD method. The book describes the application of FDTD method to current and emerging problems of lightning surge protection of continuously more complex installations, particularly in critical infrastructures of energy and information, such as overhead power lines, air-insulated sub-stations, wind turbine generator towers and telecommunication towers. Both authors are internationally recognized experts in the area of lightning study and this is the first book to present current research in lightning surge protection Examines in detail why lightning surges occur and what can be done to protect against them Includes theories of electromagnetic computation methods and many examples of their application Accompanied by a sample printed program based on the finite-difference time-domain (FDTD) method written in C++ program

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This accessible new edition explores the major topics in Monte Carlo simulation that have arisen over the past 30 years and presents a sound foundation for problem solving Simulation and the Monte Carlo Method, Third Edition reflects the latest developments in the field and presents a fully updated and comprehensive account of the state-of-the-art theory, methods and applications that have emerged in Monte Carlo simulation since the publication of the classic First Edition over more than a quarter of a century ago. While maintaining its accessible and intuitive approach, this revised edition features a wealth of up-to-date information that facilitates a deeper understanding of problem solving across a wide array of subject areas, such as engineering, statistics, computer science, mathematics, and the physical and life sciences. The book begins with a modernized introduction that addresses the basic concepts of probability, Markov processes, and convex optimization. Subsequent chapters discuss the dramatic changes that have occurred in the field of the Monte Carlo method, with coverage of many modern topics including: Markov Chain Monte Carlo, variance reduction techniques such as importance (re-)sampling, and the transform likelihood ratio method, the score function method for sensitivity analysis, the stochastic approximation method and the stochastic counter-part method for Monte Carlo optimization, the cross-entropy method for rare events estimation and combinatorial optimization, and application of Monte Carlo techniques for counting problems. An extensive range of exercises is provided at the end of each chapter, as well as a generous sampling of applied examples. The Third Edition features a new chapter on the highly versatile splitting method, with applications to rare-event estimation, counting, sampling, and optimization. A second new chapter introduces the stochastic enumeration method, which is a new fast sequential Monte Carlo method for tree search. In addition, the Third Edition features new material on: • Random number generation, including multiple-recursive generators and the Mersenne Twister • Simulation of Gaussian processes, Brownian motion, and diffusion processes • Multilevel Monte Carlo method • New enhancements of the cross-entropy (CE) method, including the “improved” CE method, which uses sampling from the zero-variance distribution to find the optimal importance sampling parameters • Over 100 algorithms in modern pseudo code with flow control • Over 25 new exercises Simulation and the Monte Carlo Method, Third Edition is an excellent text for upper-undergraduate and beginning graduate courses in stochastic simulation and Monte Carlo techniques. The book also serves as a valuable reference for professionals who would like to achieve a more formal understanding of the Monte Carlo method. Reuven Y. Rubinstein, DSc, was Professor Emeritus in the Faculty of Industrial Engineering and Management at Technion-Israel Institute of Technology. He served as a consultant at numerous large-scale organizations, such as IBM, Motorola, and NEC. The author of over 100 articles and six books, Dr. Rubinstein was also the inventor of the popular score-function method in simulation analysis and generic cross-entropy methods for combinatorial optimization and counting. Dirk P. Kroese, PhD, is a Professor of Mathematics and Statistics in the School of Mathematics and Physics of The University of Queensland, Australia. He has published over 100 articles and four books in a wide range of areas in applied probability and statistics, including Monte Carlo methods, cross-entropy, randomized algorithms, tele-traffic c theory, reliability, computational statistics, applied probability, and stochastic modeling.
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