prediction of glycinenmda receptor antagonism



Masashi Hayakawa Earthquake Prediction with Radio Techniques Masashi Hayakawa Earthquake Prediction with Radio Techniques Новинка

Masashi Hayakawa Earthquake Prediction with Radio Techniques

12746.87 руб.
The latest achievements of earthquake prediction via radio communication systems, by the world's leading authority Prof. Hayakawa is one of the world leaders in the field of seismo-electromagnetics for EQ prediction and this area of research is still evolving Presents the fundamentals of radio communications and radio propagation, using the radio noises and propagation anomalies as a precursor of earthquakes Considers the combination of different kinds of seismogenic electromagnetic signals of both natural and artificial character Timely topic following the recent sequence of highly destructive earthquakes around the world
Artem Oganov R. Modern Methods of Crystal Structure Prediction Artem Oganov R. Modern Methods of Crystal Structure Prediction Новинка

Artem Oganov R. Modern Methods of Crystal Structure Prediction

16399.25 руб.
Gathering leading specialists in the field of structure prediction, this book provides a unique view of this complex and rapidly developing field, reflecting the numerous viewpoints of the different authors. A summary of the major achievements over the last few years and of the challenges still remaining makes this monograph very timely.
Michael Roberts F. Receptor Biology Michael Roberts F. Receptor Biology Новинка

Michael Roberts F. Receptor Biology

7123.25 руб.
This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on covering each receptor superfamily in detail including their structure and evolutionary context. The last part focusses exclusively on examples where thorough knowledge of receptors is critical: pharmaceutical research, developmental biology, neurobiology and evolutionary biology. Richly illustrated, the book is perfectly suited for all courses covering receptor based signaling, regardless whether they are part of the biology, medicine or pharmacology program.
Edward Anderson Reliability Prediction and Testing Textbook Edward Anderson Reliability Prediction and Testing Textbook Новинка

Edward Anderson Reliability Prediction and Testing Textbook

9579 руб.
This textbook reviews the methodologies of reliability prediction as currently used in industries such as electronics, automotive, aircraft, aerospace, off-highway, farm machinery, and others. It then discusses why these are not successful; and, presents methods developed by the authors for obtaining accurate information for successful prediction. The approach is founded on approaches that accurately duplicate the real world use of the product. Their approach is based on two fundamental components needed for successful reliability prediction; first, the methodology necessary; and, second, use of accelerated reliability and durability testing as a source of the necessary data. Applicable to all areas of engineering, this textbook details the newest techniques and tools to achieve successful reliabilityprediction and testing. It demonstrates practical examples of the implementation of the approaches described. This book is a tool for engineers, managers, researchers, in industry, teachers, and students. The reader will learn the importance of the interactions of the influencing factors and the interconnections of safety and human factors in product prediction and testing.
Catherine Spong Y. Stillbirth. Prediction, Prevention and Management Catherine Spong Y. Stillbirth. Prediction, Prevention and Management Новинка

Catherine Spong Y. Stillbirth. Prediction, Prevention and Management

13636.66 руб.
Stillbirth remains a major and tragic obstetric complication The number of deaths due to stillbirth are greater than those due to preterm birth and sudden infant death syndrome combined. Stillbirth: Prediction, Prevention and Management provides a comprehensive guide to the topic of stillbirth. Distilling recent groundbreaking research, expert authors consider: The epidemiology of stillbirth throughout the world The various possible causes of stillbirth The psychological effects on mothers and families who suffer a stillbirth Management of stillbirth Managing pregnancies following stillbirth Stillbirth: Prediction, Prevention and Management is packed with crucial evidence-based information and practical insights. It enables all obstetric healthcare providers to manage one of the most traumatic yet all too common situations they will encounter.
Emanuela Corsini Molecular Immunotoxicology Emanuela Corsini Molecular Immunotoxicology Новинка

Emanuela Corsini Molecular Immunotoxicology

14622.12 руб.
The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.
Raimo Pohjanvirta The AH Receptor in Biology and Toxicology Raimo Pohjanvirta The AH Receptor in Biology and Toxicology Новинка

Raimo Pohjanvirta The AH Receptor in Biology and Toxicology

13100.24 руб.
This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.
Dominique Bonneau Internal Combustion Engine Bearings Lubrication in Hydrodynamic Bearings Dominique Bonneau Internal Combustion Engine Bearings Lubrication in Hydrodynamic Bearings Новинка

Dominique Bonneau Internal Combustion Engine Bearings Lubrication in Hydrodynamic Bearings

10497.42 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book with the specific case of internal combustion engine (ICE) journal bearing lubrication. Many examples, relating to various types of ICE, are presented.
Armin Bunde Extreme Events and Natural Hazards. The Complexity Perspective Armin Bunde Extreme Events and Natural Hazards. The Complexity Perspective Новинка

Armin Bunde Extreme Events and Natural Hazards. The Complexity Perspective

9598.21 руб.
Published by the American Geophysical Union as part of the Geophysical Monograph Series, Volume 196. Extreme Events and Natural Hazards: The Complexity Perspective examines recent developments in complexity science that provide a new approach to understanding extreme events. This understanding is critical to the development of strategies for the prediction of natural hazards and mitigation of their adverse consequences. The volume is a comprehensive collection of current developments in the understanding of extreme events. The following critical areas are highlighted: understanding extreme events, natural hazard prediction and development of mitigation strategies, recent developments in complexity science, global change and how it relates to extreme events, and policy sciences and perspective. With its overarching theme, Extreme Events and Natural Hazards will be of interest and relevance to scientists interested in nonlinear geophysics, natural hazards, atmospheric science, hydrology, oceanography, tectonics, and space weather.
Edward Petersen Single Event Effects in Aerospace Edward Petersen Single Event Effects in Aerospace Новинка

Edward Petersen Single Event Effects in Aerospace

11954.59 руб.
This book introduces the basic concepts necessary to understand Single Event phenomena which could cause random performance errors and catastrophic failures to electronics devices. As miniaturization of electronics components advances, electronics components are more susceptible in the radiation environment. The book includes a discussion of the radiation environments in space and in the atmosphere, radiation rate prediction depending on the orbit to allow electronics engineers to design and select radiation tolerant components and systems, and single event prediction.
Christine Rochange Time-Predictable Architectures Christine Rochange Time-Predictable Architectures Новинка

Christine Rochange Time-Predictable Architectures

6823.75 руб.
Building computers that can be used to design embedded real-time systems is the subject of this title. Real-time embedded software requires increasingly higher performances. The authors therefore consider processors that implement advanced mechanisms such as pipelining, out-of-order execution, branch prediction, cache memories, multi-threading, multicorearchitectures, etc. The authors of this book investigate the timepredictability of such schemes.
Leonid Buryakovsky Fundamentals of the Petrophysics of Oil and Gas Reservoirs Leonid Buryakovsky Fundamentals of the Petrophysics of Oil and Gas Reservoirs Новинка

Leonid Buryakovsky Fundamentals of the Petrophysics of Oil and Gas Reservoirs

15896.23 руб.
Written by some of the world’s most renowned petroleum and environmental engineers, Petrophysics: The Fundamentals of Oil and Gas Revervoirs is the first book to offer the practicing engineer and engineering student these new cutting-edge techniques for prediction and forecasting in petroleum engineering and environmental management.
Gomtsyan Arthur Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders Gomtsyan Arthur Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders Новинка

Gomtsyan Arthur Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders

12261.12 руб.
Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis, chronic low back pain, neuropathic pain, and cancer pain, some consider it «the holy grail» of pain management. This dedicated reference summarizes available data related to the potential therapeutic utility for TRPV1 ligands. With contributions from many of the world's leading experts on TRP channels, Vanilloid Receptor TRPV1 in Drug Discovery covers the important TRPV1 target for drugs to treat painful conditions such as inflammation, arthritis, and cancer pain. The book discusses: Recent advances in biology, chemistry, and pharmacology at both the preclinical and clinical stage of the dynamic area of TRPV1 drug discovery research The potential for drugs targeting TRPV1 in painful conditions such as inflammation, arthritis, and cancer The development of analgesic drugs Other applications for TRPV1, including the treatment of respiratory disease and diabetes Featuring data relevant to the therapeutic potential of TRPV1 and the medicinal chemistry involved in designing TRPV1 antagonists, Vanilloid Receptor TRPV1 in Drug Discovery is a key tool for researchers in the pharmaceutical industry and academia involved in pain, ion channels, and analgesic drug development.
Yatsimirsky Anatoly Artificial Receptors for Chemical Sensors Yatsimirsky Anatoly Artificial Receptors for Chemical Sensors Новинка

Yatsimirsky Anatoly Artificial Receptors for Chemical Sensors

16399.25 руб.
The first to provide systematically organized information on all three important aspects of artificial receptor design, this book brings together knowledge on an exceptionally hot and multidisciplinary field of research. Strong emphasis is placed on the methodology for discovering artificial receptors, with both definitions for chemosensitivity as well as experimental setups supplied. There follows coverage of numerous classes of artificial receptors, including synthesis, immobilization on surfaces, and quantitative data on properties. The third part of the book focuses on receptor arrays for artificial nose and tongue applications and the whole is rounded off with an outlook and an appendix with all relevant quantitative data on artificial receptors.
O'Connor Patrick Practical Reliability Engineering O'Connor Patrick Practical Reliability Engineering Новинка

O'Connor Patrick Practical Reliability Engineering

13487.23 руб.
With emphasis on practical aspects of engineering, this bestseller has gained worldwide recognition through progressive editions as the essential reliability textbook. This fifth edition retains the unique balanced mixture of reliability theory and applications, thoroughly updated with the latest industry best practices. Practical Reliability Engineering fulfils the requirements of the Certified Reliability Engineer curriculum of the American Society for Quality (ASQ). Each chapter is supported by practice questions, and a solutions manual is available to course tutors via the companion website. Enhanced coverage of mathematics of reliability, physics of failure, graphical and software methods of failure data analysis, reliability prediction and modelling, design for reliability and safety as well as management and economics of reliability programmes ensures continued relevance to all quality assurance and reliability courses. Notable additions include: New chapters on applications of Monte Carlo simulation methods and reliability demonstration methods. Software applications of statistical methods, including probability plotting and a wider use of common software tools. More detailed descriptions of reliability prediction methods. Comprehensive treatment of accelerated test data analysis and warranty data analysis. Revised and expanded end-of-chapter tutorial sections to advance students’ practical knowledge. The fifth edition will appeal to a wide range of readers from college students to seasoned engineering professionals involved in the design, development, manufacture and maintenance of reliable engineering products and systems. www.wiley.com/go/oconnor_reliability5
Jacques Verdu Oxydative Ageing of Polymers Jacques Verdu Oxydative Ageing of Polymers Новинка

Jacques Verdu Oxydative Ageing of Polymers

14176.92 руб.
This book aims to rehabilitate kinetic modeling in the domain of polymer ageing, where it has been almost abandoned by the research community. Kinetic modeling is a key step for lifetime prediction, a crucial problem in many industrial domains in which needs cannot be satisfied by the common empirical methods. The book proposes a renewed approach of lifetime prediction in polymer oxidative ageing. This approach is based on kinetic models built from relatively simple mechanistic schemes but integrating physical processes (oxygen diffusion and stabilizer transport), and use property (for instance mechanical failure) changes. An important chapter is dedicated to radiation-induced oxidation and its most important applications: radiochemical ageing at low dose rates and photo-chemical ageing under solar radiation. There is also a chapter devoted to the problem of ageing under coupled oxidation and mechanical loading.
Shouwei Zhou Sand Production Management for Unconsolidated Sandstone Reservoirs Shouwei Zhou Sand Production Management for Unconsolidated Sandstone Reservoirs Новинка

Shouwei Zhou Sand Production Management for Unconsolidated Sandstone Reservoirs

8997.79 руб.
This book investigates sand production problems in the development of unconsolidated sand reservoirs and suggests novel technical solutions and improvements to sand management issues. This book is divided into six chapters: (1) geologic characteristics of unconsolidated sand heavy oil reservoirs and concept of sand management technology; (2) sand production mechanisms and its effect on reservoir petrophysical quality; (3) sand production quantity prediction and well productivity evaluation methods, especially for fluid-solid coupling prediction model; (4) completion technology for sand management; (5) sand flow in well bore and surface processing; (6) the application of sand management technology in China’s Bohai heavy oil field. Readership: Petroleum reservoir engineers and production managers worldwide.
Manjubala Bisi Artificial Neural Network Applications for Software Reliability Prediction Manjubala Bisi Artificial Neural Network Applications for Software Reliability Prediction Новинка

Manjubala Bisi Artificial Neural Network Applications for Software Reliability Prediction

14622.12 руб.
Artificial neural network (ANN) has proven to be a universal approximator for any non-linear continuous function with arbitrary accuracy. This book presents how to apply ANN to measure various software reliability indicators: number of failures in a given time, time between successive failures, fault-prone modules and development efforts. The application of machine learning algorithm i.e. artificial neural networks application in software reliability prediction during testing phase as well as early phases of software development process is presented as well. Applications of artificial neural network for the above purposes are discussed with experimental results in this book so that practitioners can easily use ANN models for predicting software reliability indicators.
Edith Hotchkiss Corporate Financial Distress and Bankruptcy. Predict and Avoid Bankruptcy, Analyze and Invest in Distressed Debt Edith Hotchkiss Corporate Financial Distress and Bankruptcy. Predict and Avoid Bankruptcy, Analyze and Invest in Distressed Debt Новинка

Edith Hotchkiss Corporate Financial Distress and Bankruptcy. Predict and Avoid Bankruptcy, Analyze and Invest in Distressed Debt

8429.52 руб.
A comprehensive look at the enormous growth and evolution of distressed debt, corporate bankruptcy, and credit risk default This Third Edition of the most authoritative finance book on the topic updates and expands its discussion of corporate distress and bankruptcy, as well as the related markets dealing with high-yield and distressed debt, and offers state-of-the-art analysis and research on the costs of bankruptcy, credit default prediction, the post-emergence period performance of bankrupt firms, and more.
Jasmina Hasanhodzic The Evolution of Technical Analysis. Financial Prediction from Babylonian Tablets to Bloomberg Terminals Jasmina Hasanhodzic The Evolution of Technical Analysis. Financial Prediction from Babylonian Tablets to Bloomberg Terminals Новинка

Jasmina Hasanhodzic The Evolution of Technical Analysis. Financial Prediction from Babylonian Tablets to Bloomberg Terminals

1910.8 руб.
A comprehensive history of the evolution of technical analysis from ancient times to the Internet age Whether driven by mass psychology, fear or greed of investors, the forces of supply and demand, or a combination, technical analysis has flourished for thousands of years on the outskirts of the financial establishment. In The Evolution of Technical Analysis: Financial Prediction from Babylonian Tablets to Bloomberg Terminals, MIT's Andrew W. Lo details how the charting of past stock prices for the purpose of identifying trends, patterns, strength, and cycles within market data has allowed traders to make informed investment decisions based in logic, rather than on luck. The book Reveals the origins of technical analysis Compares and contrasts the Eastern practices of China and Japan to Western methods Details the contributions of pioneers such as Charles Dow, Munehisa Homma, Humphrey B. Neill, and William D. Gann The Evolution of Technical Analysis explores the fascinating history of technical analysis, tracing where technical analysts failed, how they succeeded, and what it all means for today's traders and investors.
Jan Magnus The price of Moscow apartments Jan Magnus The price of Moscow apartments Новинка

Jan Magnus The price of Moscow apartments

79.9 руб.
We present a simple hedonic model for apartment prices in Moscow in the year 2003. Based on some 15,000 observations we estimate the model and use the estimates for prediction. Pretest issues are explicitly taken into account.
Dominique Bonneau Mixed Lubrication in Hydrodynamic Bearings Dominique Bonneau Mixed Lubrication in Hydrodynamic Bearings Новинка

Dominique Bonneau Mixed Lubrication in Hydrodynamic Bearings

8922.38 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book is dedicated to the mixed lubrication.
Dominique Bonneau Thermo-hydrodynamic Lubrication in Hydrodynamic Bearings Dominique Bonneau Thermo-hydrodynamic Lubrication in Hydrodynamic Bearings Новинка

Dominique Bonneau Thermo-hydrodynamic Lubrication in Hydrodynamic Bearings

7344.49 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book describes the thermo-hydrodynamic and the thermo-elasto-hydrodynamic lubrication. The algorithms are methodically detailed and each section is thoroughly illustrated.
Dominique Bonneau Hydrodynamic Bearings Dominique Bonneau Hydrodynamic Bearings Новинка

Dominique Bonneau Hydrodynamic Bearings

8922.38 руб.
This Series provides the necessary elements to the development and validation of numerical prediction models for hydrodynamic bearings. This book describes the rheological models and the equations of lubrication. It also presents the numerical approaches used to solve the above equations by finite differences, finite volumes and finite elements methods.
Robert Melchers E. Structural Reliability Analysis and Prediction Robert Melchers E. Structural Reliability Analysis and Prediction Новинка

Robert Melchers E. Structural Reliability Analysis and Prediction

7494.6 руб.
Structural Reliability Analysis and Prediction, Third Edition is a textbook which addresses the important issue of predicting the safety of structures at the design stage and also the safety of existing, perhaps deteriorating structures. Attention is focused on the development and definition of limit states such as serviceability and ultimate strength, the definition of failure and the various models which might be used to describe strength and loading. This book emphasises concepts and applications, built up from basic principles and avoids undue mathematical rigour. It presents an accessible and unified account of the theory and techniques for the analysis of the reliability of engineering structures using probability theory. This new edition has been updated to cover new developments and applications and a new chapter is included which covers structural optimization in the context of reliability analysis. New examples and end of chapter problems are also now included.
Adrian Graham Communications, Radar and Electronic Warfare Adrian Graham Communications, Radar and Electronic Warfare Новинка

Adrian Graham Communications, Radar and Electronic Warfare

9885.53 руб.
A practical guide to the principles of radio communications for both civilian and military applications In this book, the author covers both the civilian and military uses of technology, focusing particularly on the applications of radio propagation and prediction. Divided into two parts, the author introduces the basic theory of radio prediction before providing a step-by-step explanation of how this theory can be translated into real-life applications. In addition, the book presents up-to-date systems and methods to illustrate how these applications work in practice. This includes systems working in the HF bands and SHF. Furthermore, the author examines the performance of these systems, and also the effects of noise, interference and deliberate jamming, as well as the performance of jamming, detection and intercept systems. Particular attention is paid to the problems caused by Radio Controlled Improvised Explosive Devices (RCIEDs). Key Features: A practical handbook on the topic of radio communications and propagation Written by an expert in both the civilian and military applications of the technology Focuses on methods such as radio and radar jamming, and radio-controlled improvised explosive devices (IEDs) Contains problems and solutions to clarify key topics
Rafael Gouriveau From Prognostics and Health Systems Management to Predictive Maintenance 1. Monitoring and Prognostics Rafael Gouriveau From Prognostics and Health Systems Management to Predictive Maintenance 1. Monitoring and Prognostics Новинка

Rafael Gouriveau From Prognostics and Health Systems Management to Predictive Maintenance 1. Monitoring and Prognostics

10244.16 руб.
This book addresses the steps needed to monitor health assessment systems and the anticipation of their failures: choice and location of sensors, data acquisition and processing, health assessment and prediction of the duration of residual useful life. The digital revolution and mechatronics foreshadowed the advent of the 4.0 industry where equipment has the ability to communicate. The ubiquity of sensors (300,000 sensors in the new generations of aircraft) produces a flood of data requiring us to give meaning to information and leads to the need for efficient processing and a relevant interpretation. The process of traceability and capitalization of data is a key element in the context of the evolution of the maintenance towards predictive strategies.
Andreas Ochsner Cellular and Porous Materials. Thermal Properties Simulation and Prediction Andreas Ochsner Cellular and Porous Materials. Thermal Properties Simulation and Prediction Новинка

Andreas Ochsner Cellular and Porous Materials. Thermal Properties Simulation and Prediction

21594.55 руб.
Providing the reader with a solid understanding of the fundamentals as well as an awareness of recent advances in properties and applications of cellular and porous materials, this handbook and ready reference covers all important analytical and numerical methods for characterizing and predicting thermal properties. In so doing it directly addresses the special characteristics of foam-like and hole-riddled materials, combining theoretical and experimental aspects for characterization purposes.
ANNE WEALE Worthy Of Marriage ANNE WEALE Worthy Of Marriage Новинка

ANNE WEALE Worthy Of Marriage

116.67 руб.
Grey Calderwood was furious to discover that his mother had employed Lucia Graham–the woman he believed had defrauded him…Lucia knew she'd wronged Grey, but she had been desperate to help her father. Now that they'd been thrown together, the atmosphere between her and Grey was explosive–part antagonism, part burning attraction… Could this proud, powerful man ever trust Lucia again, and believe her to be worthy of his love?
Steven Tucker A Collection of Surveys on Market Experiments Steven Tucker A Collection of Surveys on Market Experiments Новинка

Steven Tucker A Collection of Surveys on Market Experiments

2620.8 руб.
Comprised of 10 surveys by leading scholars, this collection showcases the largest and fastest growing strands of research on market behaviour in experimental economics. Covers topics such as asset markets, contests, environmental policy, frictions, general equilibrium, labour markets, multi-unit auctions, oligopoly markets, and prediction markets Focuses on the literature that has helped economists best understand how markets operate Assesses the impact of developments in theory, policy, and research methods
Sana Salous Radio Propagation Measurement and Channel Modelling Sana Salous Radio Propagation Measurement and Channel Modelling Новинка

Sana Salous Radio Propagation Measurement and Channel Modelling

10192.06 руб.
While there are numerous books describing modern wireless communication systems that contain overviews of radio propagation and radio channel modelling, there are none that contain detailed information on the design, implementation and calibration of radio channel measurement equipment, the planning of experiments and the in depth analysis of measured data. The book would begin with an explanation of the fundamentals of radio wave propagation and progress through a series of topics, including the measurement of radio channel characteristics, radio channel sounders, measurement strategies, data analysis techniques and radio channel modelling. Application of results for the prediction of achievable digital link performance would be discussed with examples pertinent to single carrier, multi-carrier and spread spectrum radio links. This work would address specifics of communications in various different frequency bands for both long range and short range fixed and mobile radio links.
Kazakovtsev B. A. Mental Disorders in Epilepsy Kazakovtsev B. A. Mental Disorders in Epilepsy Новинка

Kazakovtsev B. A. Mental Disorders in Epilepsy

1292 руб.
The monograph shows the opportunity to study the pathogenesis of mental disorders in epilepsy based on the characteristics of its flow using clinical methods, structural dynamic, epidemiological and statistical analysis. Structural and dynamic analysis of the major clinical manifestations of the disease (features of personality changes, paroxysmal disorders, psychotic symptoms, dementia) held in accordance with the main patterns of development of the disease, its types and stages. On the basis of the multi-axial classification of epilepsy was developed a model that allows in a retrospective analysis of anamnestic data and clinical assessment to establish clinical and social criteria for prognosis prediction
B. A. Kazakovtsev Mental Disorders in Epilepsy B. A. Kazakovtsev Mental Disorders in Epilepsy Новинка

B. A. Kazakovtsev Mental Disorders in Epilepsy

400 руб.
The monograph shows the opportunity to study the pathogenesis of mental disorders in epilepsy based on the characteristics of its fl ow using clinical methods, structural dynamic, epidemiological and statistical analysis. Structural and dynamic analysis of the major clinical manifestations of the disease (features of personality changes, paroxysmal disorders, psychotic symptoms, dementia) held in accordance with the main patterns of development of the disease, its types and stages. On the basis of the multi-axial classifi cation of epilepsy was developed a model that allows in a retrospective analysis of an-amnestic data and clinical assessment to establish clinical and social criteria for prognosis prediction.
Gareth Padfield D. Helicopter Flight Dynamics. Including a Treatment of Tiltrotor Aircraft Gareth Padfield D. Helicopter Flight Dynamics. Including a Treatment of Tiltrotor Aircraft Новинка

Gareth Padfield D. Helicopter Flight Dynamics. Including a Treatment of Tiltrotor Aircraft

9259.7 руб.
The Book The behaviour of helicopters and tiltrotor aircraft is so complex that understanding the physical mechanisms at work in trim, stability and response, and thus the prediction of Flying Qualities, requires a framework of analytical and numerical modelling and simulation. Good Flying Qualities are vital for ensuring that mission performance is achievable with safety and, in the first and second editions of Helicopter Flight Dynamics, a comprehensive treatment of design criteria was presented, relating to both normal and degraded Flying Qualities. Fully embracing the consequences of Degraded Flying Qualities during the design phase will contribute positively to safety. In this third edition, two new Chapters are included. Chapter 9 takes the reader on a journey from the origins of the story of Flying Qualities, tracing key contributions to the developing maturity and to the current position. Chapter 10 provides a comprehensive treatment of the Flight Dynamics of tiltrotor aircraft; informed by research activities and the limited data on operational aircraft. Many of the unique behavioural characteristics of tiltrotors are revealed for the first time in this book. The accurate prediction and assessment of Flying Qualities draws on the modelling and simulation discipline on the one hand and testing practice on the other. Checking predictions in flight requires clearly defined mission tasks, derived from realistic performance requirements. High fidelity simulations also form the basis for the design of stability and control augmentation systems, essential for conferring Level 1 Flying Qualities. The integrated description of flight dynamic modelling, simulation and flying qualities of rotorcraft forms the subject of this book, which will be of interest to engineers practising and honing their skills in research laboratories, academia and manufacturing industries, test pilots and flight test engineers, and as a reference for graduate and postgraduate students in aerospace engineering.
Mario Chavez Extreme Events. Observations, Modeling, and Economics Mario Chavez Extreme Events. Observations, Modeling, and Economics Новинка

Mario Chavez Extreme Events. Observations, Modeling, and Economics

14993.47 руб.
The monograph covers the fundamentals and the consequences of extreme geophysical phenomena like asteroid impacts, climatic change, earthquakes, tsunamis, hurricanes, landslides, volcanic eruptions, flooding, and space weather. This monograph also addresses their associated, local and worldwide socio-economic impacts. The understanding and modeling of these phenomena is critical to the development of timely worldwide strategies for the prediction of natural and anthropogenic extreme events, in order to mitigate their adverse consequences. This monograph is unique in as much as it is dedicated to recent theoretical, numerical and empirical developments that aim to improve: (i) the understanding, modeling and prediction of extreme events in the geosciences, and, (ii) the quantitative evaluation of their economic consequences. The emphasis is on coupled, integrative assessment of the physical phenomena and their socio-economic impacts. With its overarching theme, Extreme Events: Observations, Modeling and Economics will be relevant to and become an important tool for researchers and practitioners in the fields of hazard and risk analysis in general, as well as to those with a special interest in climate change, atmospheric and oceanic sciences, seismo-tectonics, hydrology, and space weather.
Wouter Schellart P. Plate Boundaries and Natural Hazards Wouter Schellart P. Plate Boundaries and Natural Hazards Новинка

Wouter Schellart P. Plate Boundaries and Natural Hazards

14242.94 руб.
The beginning of the new millennium has been particularly devastating in terms of natural disasters associated with tectonic plate boundaries, such as earthquakes in Sumatra, Chile, Japan, Tahiti, and Nepal; the Indian Ocean and the Pacific Ocean tsunamis; and volcanoes in Indonesia, Chile, Iceland that have produced large quantities of ash causing major disruption to aviation. In total, half a million people were killed by such natural disasters. These recurring events have increased our awareness of the destructive power of natural hazards and the major risks associated with them. While we have come a long way in the search for understanding such natural phenomena, and although our knowledge of Earth dynamics and plate tectonics has improved enormously, there are still fundamental uncertainties in our understanding of natural hazards. Increased understanding is crucial to improve our capacity for hazard prediction and mitigation. Volume highlights include: Main concepts associated with tectonic plate boundaries Novel studies on boundary-related natural hazards Fundamental concepts that improve hazard prediction and mitigation Plate Boundaries and Natural Hazards will be a valuable resource for scientists and students in the fields of geophysics, geochemistry, plate tectonics, natural hazards, and climate science.
Jörg Grunenberg Computational Spectroscopy. Methods, Experiments and Applications Jörg Grunenberg Computational Spectroscopy. Methods, Experiments and Applications Новинка

Jörg Grunenberg Computational Spectroscopy. Methods, Experiments and Applications

16646.05 руб.
Unique in its comprehensive coverage of not only theoretical methods but also applications in computational spectroscopy, this ready reference and handbook compiles the developments made over the last few years, from single molecule studies to the simulation of clusters and the solid state, from organic molecules to complex inorganic systems and from basic research to commercial applications in the area of environment relevance. In so doing, it covers a multitude of apparatus-driven technologies, starting with the common and traditional spectroscopic methods, more recent developments (THz), as well as rather unusual methodologies and systems, such as the prediction of parity violation, rare gas HI complexes or theoretical spectroscopy of the transition state. With its summarized results of so many different disciplines, this timely book will be of interest to newcomers to this hot topic while equally informing experts about developments in neighboring fields.
Отсутствует Design and Analysis of Centrifugal Compressors Отсутствует Design and Analysis of Centrifugal Compressors Новинка

Отсутствует Design and Analysis of Centrifugal Compressors

12874.18 руб.
A comprehensive overview of fluid dynamic models and experimental results that can help solve problems in centrifugal compressors and modern techniques for a more efficient aerodynamic design. Design and Analysis of Centrifugal Compressors isacomprehensive overview of the theoretical fluid dynamic models describing the flow in centrifugal compressors and the modern techniques for the design of more efficient centrifugal compressors. The author – a noted expert in the field, with over 40 years of experience – evaluates relevant numerical and analytical prediction models for centrifugal compressors with special attention to their accuracy and limitations. Relevant knowledge from the last century is linked with new insights obtained from modern CFD. Emphasis is to link the flow structure, performance and stability to the geometry of the different compressor components. Design and Analysis of Centrifugal Compressors is an accessible resource that combines theory with experimental data and previous research with recent developments in computational design and optimization. This important resource Covers the basic information concerning fluid dynamics that are specific for centrifugal compressors and clarifies the differences with axial compressors Provides an overview of performance prediction models previously developed in combination with extra results from research conducted by the author Describes helpful numerical and analytical models for the flow in the different components in relation to flow stability, operating range and performance Includes the fundamental information for the aerodynamic design of more efficient centrifugal compressors Explains the use of computational fluid dynamics (CFD) for the design and analysis of centrifugal compressors Written for engineers, researchers and designers in industry as well as for academics specializing in the field, Design and Analysis of Centrifugal Compressors offers an up to date overview of the information needed for the design of more effective centrifugal compressors.
Storey Richard A. Solid State Characterization of Pharmaceuticals Storey Richard A. Solid State Characterization of Pharmaceuticals Новинка

Storey Richard A. Solid State Characterization of Pharmaceuticals

19004.74 руб.
The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included: Physical properties and processes Thermodynamics Intellectual guidance X-ray diffraction Spectroscopy Microscopy Particle sizing Mechanical properties Vapour sorption Thermal analysis & Calorimetry Polymorph prediction Form selection
Richard Hodges P. Underwater Acoustics. Analysis, Design and Performance of Sonar Richard Hodges P. Underwater Acoustics. Analysis, Design and Performance of Sonar Новинка

Richard Hodges P. Underwater Acoustics. Analysis, Design and Performance of Sonar

14330.18 руб.
Offering complete and comprehensive coverage of modern sonar spectrum system analysis, Underwater Acoustics: Analysis, Design and Performance of Sonar provides a state-of-the-art introduction to the subject and has been carefully structured to offer a much-needed update to the classic text by Urick. Expanded to included computational approaches to the topic, this book treads the line between the highly theoretical and mathematical texts and the more populist, non-mathematical books that characterize the existing literature in the field. The author compares and contrasts different techniques for sonar design, analysis and performance prediction and includes key experimental and theoretical results, pointing the reader towards further detail with extensive references. Practitioners in the field of sonar design, analysis and performance prediction as well as graduate students and researchers will appreciate this new reference as an invaluable and timely contribution to the field. Chapters include the sonar equation, radiated, self and ambient noise, active sonar sources, transmission loss, reverberation, transducers, active target strength, statistical detection theory, false alarms, contacts and targets, variability and uncertainty, modelling detections and tactical decision aids, cumulative probability of detection, tracking target motion analysis and localization, and design and evaluation of sonars
Antonios Alexandridis K. Wavelet Neural Networks. With Applications in Financial Engineering, Chaos, and Classification Antonios Alexandridis K. Wavelet Neural Networks. With Applications in Financial Engineering, Chaos, and Classification Новинка

Antonios Alexandridis K. Wavelet Neural Networks. With Applications in Financial Engineering, Chaos, and Classification

7722.96 руб.
A step-by-step introduction to modeling, training, and forecasting using wavelet networks Wavelet Neural Networks: With Applications in Financial Engineering, Chaos, and Classification presents the statistical model identification framework that is needed to successfully apply wavelet networks as well as extensive comparisons of alternate methods. Providing a concise and rigorous treatment for constructing optimal wavelet networks, the book links mathematical aspects of wavelet network construction to statistical modeling and forecasting applications in areas such as finance, chaos, and classification. The authors ensure that readers obtain a complete understanding of model identification by providing in-depth coverage of both model selection and variable significance testing. Featuring an accessible approach with introductory coverage of the basic principles of wavelet analysis, Wavelet Neural Networks: With Applications in Financial Engineering, Chaos, and Classification also includes: • Methods that can be easily implemented or adapted by researchers, academics, and professionals in identification and modeling for complex nonlinear systems and artificial intelligence • Multiple examples and thoroughly explained procedures with numerous applications ranging from financial modeling and financial engineering, time series prediction and construction of confidence and prediction intervals, and classification and chaotic time series prediction • An extensive introduction to neural networks that begins with regression models and builds to more complex frameworks • Coverage of both the variable selection algorithm and the model selection algorithm for wavelet networks in addition to methods for constructing confidence and prediction intervals Ideal as a textbook for MBA and graduate-level courses in applied neural network modeling, artificial intelligence, advanced data analysis, time series, and forecasting in financial engineering, the book is also useful as a supplement for courses in informatics, identification and modeling for complex nonlinear systems, and computational finance. In addition, the book serves as a valuable reference for researchers and practitioners in the fields of mathematical modeling, engineering, artificial intelligence, decision science, neural networks, and finance and economics.
Engels Friedrich The Communist Manifesto Engels Friedrich The Communist Manifesto Новинка

Engels Friedrich The Communist Manifesto

349 руб.
The Communist Manifesto, originally titled Manifesto of the Communist Party (German: Manifest der Kommunistischen Partei) is a short 1848 book written by the German Marxist political theorists Karl Marx and Friedrich Engels. It has since been recognized as one of the world's most influential political manuscripts. Commissioned by the Communist League, it laid out the League's purposes and program. It presents an analytical approach to the class struggle (historical and present) and the problems of capitalism, rather than a prediction of communism's potential future forms. The book contains Marx and Engels' Marxist theories about the nature of society and politics, that in their own words, «The history of all hitherto existing society is the history of class struggles.» It also briefly features their ideas for how the capitalist society of the time would eventually be replaced by socialism, and then eventually communism.
Brigitte Chebel-Morello From Prognostics and Health Systems Management to Predictive Maintenance 2. Knowledge, Reliability and Decision Brigitte Chebel-Morello From Prognostics and Health Systems Management to Predictive Maintenance 2. Knowledge, Reliability and Decision Новинка

Brigitte Chebel-Morello From Prognostics and Health Systems Management to Predictive Maintenance 2. Knowledge, Reliability and Decision

9372.7 руб.
This book is the second volume in a set of books dealing with the evolution of technology, IT and organizational approaches and what this means for industrial equipment. The authors address this increasing complexity in two parts, focusing specifically on the field of Prognostics and Health Management (PHM). Having tackled the PHM cycle in the first volume, the purpose of this book is to tackle the other phases of PHM, including the traceability of data, information and knowledge, and the ability to make decisions accordingly. The book concludes with a summary analysis and perspectives regarding this emerging domain, since without traceability, knowledge and decision, any prediction of the health state of a system cannot be exploited.
Luonan Chen Biomolecular Networks. Methods and Applications in Systems Biology Luonan Chen Biomolecular Networks. Methods and Applications in Systems Biology Новинка

Luonan Chen Biomolecular Networks. Methods and Applications in Systems Biology

10047.81 руб.
Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.
Stanley Sandler I. Using Aspen Plus in Thermodynamics Instruction. A Step-by-Step Guide Stanley Sandler I. Using Aspen Plus in Thermodynamics Instruction. A Step-by-Step Guide Новинка

Stanley Sandler I. Using Aspen Plus in Thermodynamics Instruction. A Step-by-Step Guide

5620.06 руб.
A step-by-step guide for students (and faculty) on the use of Aspen in teaching thermodynamics • Easily-accessible modern computational techniques opening up new vistas in teaching thermodynamics A range of applications of Aspen Plus in the prediction and calculation of thermodynamic properties and phase behavior using the state-of-the art methods • Encourages students to develop engineering insight by doing repetitive calculations with changes in parameters and/or models • Calculations and application examples in a step-by-step manner designed for out-of-classroom self study • Makes it possible to easily integrate Aspen Plus into thermodynamics courses without using in-class time • Stresses the application of thermodynamics to real problems
Jay Lehr H. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils. Causes, Assessment, Prediction, Prevention, and Remediation Jay Lehr H. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils. Causes, Assessment, Prediction, Prevention, and Remediation Новинка

Jay Lehr H. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils. Causes, Assessment, Prediction, Prevention, and Remediation

11618.58 руб.
Provides the tools needed to analyze and solve acid drainage problems Featuring contributions from leading experts in science and engineering, this book explores the complex biogeochemistry of acid mine drainage, rock drainage, and acid sulfate soils. It describes how to predict, prevent, and remediate the environmental impact of acid drainage and the oxidation of sulfides, offering the latest sampling and analytical methods. Moreover, readers will discover new approaches for recovering valuable resources from acid mine drainage, including bioleaching. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils reviews the most current findings in the field, offering new insights into the underlying causes as well as new tools to minimize the harm of acid drainage: Part I: Causes of Acid Mine Drainage, Rock Drainage and Sulfate Soils focuses on the biogeochemistry of acid drainage in different environments. Part II: Assessment of Acid Mine Drainage, Rock Drainage and Sulfate Soils covers stream characterization, aquatic and biological sampling, evaluation of aquatic resources, and some unusual aspects of sulfide oxidation. Part III: Prediction and Prevention of Acid Drainage discusses acid-base accounting, kinetic testing, block modeling, petrology, and mineralogy studies. It also explains relevant policy and regulations. Part IV: Remediation of Acid Drainage, Rock Drainage and Sulfate Soils examines both passive and active cleanup methods to remediate acid drainage. Case studies from a variety of geologic settings highlight various approaches to analyzing and solving acid drainage problems. Replete with helpful appendices and an extensive list of web resources, Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils is recommended for mining engineers and scientists, regulatory officials, environmental scientists, land developers, and students.
Haibo He Self-Adaptive Systems for Machine Intelligence Haibo He Self-Adaptive Systems for Machine Intelligence Новинка

Haibo He Self-Adaptive Systems for Machine Intelligence

7506.1 руб.
This book will advance the understanding and application of self-adaptive intelligent systems; therefore it will potentially benefit the long-term goal of replicating certain levels of brain-like intelligence in complex and networked engineering systems. It will provide new approaches for adaptive systems within uncertain environments. This will provide an opportunity to evaluate the strengths and weaknesses of the current state-of-the-art of knowledge, give rise to new research directions, and educate future professionals in this domain. Self-adaptive intelligent systems have wide applications from military security systems to civilian daily life. In this book, different application problems, including pattern recognition, classification, image recovery, and sequence learning, will be presented to show the capability of the proposed systems in learning, memory, and prediction. Therefore, this book will also provide potential new solutions to many real-world applications.
Benny Bing Next-Generation Video Coding and Streaming Benny Bing Next-Generation Video Coding and Streaming Новинка

Benny Bing Next-Generation Video Coding and Streaming

7494.6 руб.
Reviews the new High Efficiency Video Coding (HEVC) standard and advancements in adaptive streaming technologies for use in broadband networks and the Internet This book describes next-generation video coding and streaming technologies with a comparative assessment of the strengths and weaknesses. Specific emphasis is placed on the H.265/HEVC video coding standard and adaptive bit rate video streaming. In addition to evaluating the impact of different types of video content and powerful feature sets on HEVC coding efficiency, the text provides an in-depth study on the practical performance of popular adaptive streaming platforms and useful tips for streaming optimization. Readers will learn of new over-the-top (OTT) online TV advancements, the direction of the broadband telecommunications industry, and the latest developments that will help keep implementation costs down and maximize return on infrastructure investment. Reviews the emerging High Efficiency Video Coding (HEVC) standard and compares its coding performance with the MPEG-4 Advanced Video Coding (AVC) and MPEG-2 standards Provides invaluable insights into the intra and inter coding efficiencies of HEVC, such as the impact of hierarchical block partitioning and new prediction modes Evaluates the performance of the Apple and Microsoft adaptive streaming platforms and presents innovative techniques related to aggregate stream bandwidth prediction, duplicate chunk Includes end-of-chapter homework problems and access to instructor slides Next-Generation Video Coding and Streaming is written for students, researchers, and industry professionals working in the field of video communications. Benny Bing has worked in academia for over 20 years. He has published over 80 research papers and 12 books, and has 6 video patents licensed to industry. He has served as a technical editor for several IEEE journals and an IEEE Communications Society Distinguished lecturer. He also received the National Association of Broadcasters (NAB) Technology Innovation Award for demonstrations of advanced media technologies.
Lev Klyatis M. Accelerated Reliability and Durability Testing Technology Lev Klyatis M. Accelerated Reliability and Durability Testing Technology Новинка

Lev Klyatis M. Accelerated Reliability and Durability Testing Technology

9522.8 руб.
Learn how ART and ADT can reduce cost, time, product recalls, and customer complaints This book provides engineers with the techniques and tools they need to use accelerated reliability testing (ART) and accelerated durability testing (ADT) as key factors to accurately predict a product's quality, reliability, durability, and maintainability during a given time, such as service life or warranty period. It covers new ideas and offers a unique approach to accurate simulation and integration of field inputs, safety, and human factors, as well as accelerated product development, as components of interdisciplinary systems engineering. Beginning with a comprehensive introduction to the subject of ART and ADT, the book covers: ART and ADT as components of an interdisciplinary systems of systems approach Methodology of ART and ADT performance Equipment for ART and ADT technology ART and ADT as sources of initial information for accurate quality, reliability, maintainability, and durability prediction and product accelerated development The economical results of the usage of ART and ADT ART and ADT standardization The book covers the newest techniques in the field and provides many case studies that illuminate how the implementation of ART and ADT can solve previously inaccessible problems in the field of engineering, such as reducing product recalls, cost, and time during design, manufacture, and usage. Professionals will find the answers to how one can carry out ART and ADT technology in a practical manner. Accelerated Reliability and Durability Testing Technology is indispensable reading for engineers, researchers in industry, usage, and academia who are involved in the design of experiments, field simulations, maintenance, reliabilty, durabilty, accurate prediction, and product development, and graduate students in related courses.
Raouf Ibrahim A. Handbook of Structural Life Assessment Raouf Ibrahim A. Handbook of Structural Life Assessment Новинка

Raouf Ibrahim A. Handbook of Structural Life Assessment

17358.87 руб.
This important, self-contained reference deals with structural life assessment (SLA) and structural health monitoring (SHM) in a combined form. SLA periodically evaluates the state and condition of a structural system and provides recommendations for possible maintenance actions or the end of structural service life. It is a diversified field and relies on the theories of fracture mechanics, fatigue damage process, and reliability theory. For common structures, their life assessment is not only governed by the theory of fracture mechanics and fatigue damage process, but by other factors such as corrosion, grounding, and sudden collision. On the other hand, SHM deals with the detection, prediction, and location of crack development online. Both SLA and SHM are combined in a unified and coherent treatment.
Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry Новинка

Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry

12644.28 руб.
A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery.
Michael Sherman Spatial Statistics and Spatio-Temporal Data. Covariance Functions and Directional Properties Michael Sherman Spatial Statistics and Spatio-Temporal Data. Covariance Functions and Directional Properties Новинка

Michael Sherman Spatial Statistics and Spatio-Temporal Data. Covariance Functions and Directional Properties

8885.48 руб.
In the spatial or spatio-temporal context, specifying the correct covariance function is fundamental to obtain efficient predictions, and to understand the underlying physical process of interest. This book focuses on covariance and variogram functions, their role in prediction, and appropriate choice of these functions in applications. Both recent and more established methods are illustrated to assess many common assumptions on these functions, such as, isotropy, separability, symmetry, and intrinsic correlation. After an extensive introduction to spatial methodology, the book details the effects of common covariance assumptions and addresses methods to assess the appropriateness of such assumptions for various data structures. Key features: An extensive introduction to spatial methodology including a survey of spatial covariance functions and their use in spatial prediction (kriging) is given. Explores methodology for assessing the appropriateness of assumptions on covariance functions in the spatial, spatio-temporal, multivariate spatial, and point pattern settings. Provides illustrations of all methods based on data and simulation experiments to demonstrate all methodology and guide to proper usage of all methods. Presents a brief survey of spatial and spatio-temporal models, highlighting the Gaussian case and the binary data setting, along with the different methodologies for estimation and model fitting for these two data structures. Discusses models that allow for anisotropic and nonseparable behaviour in covariance functions in the spatial, spatio-temporal and multivariate settings. Gives an introduction to point pattern models, including testing for randomness, and fitting regular and clustered point patterns. The importance and assessment of isotropy of point patterns is detailed. Statisticians, researchers, and data analysts working with spatial and space-time data will benefit from this book as well as will graduate students with a background in basic statistics following courses in engineering, quantitative ecology or atmospheric science.
Alex Piquero R. The Handbook of Criminological Theory Alex Piquero R. The Handbook of Criminological Theory Новинка

Alex Piquero R. The Handbook of Criminological Theory

14622.12 руб.
An indispensable resource for all levels, this handbook provides up-to-date, in-depth summaries of the most important theories in criminology. Provides original, cutting-edge, and in-depth summaries of the most important theories in criminology Covers the origins and assumptions behind each theory, explores current debates and research, points out knowledge gaps, and offers directions for future research Encompasses theory, research, policy, and practice, with recommendations for further reading at the end of each essay Features discussions of broad issues and topics related to the field, such as the correlates of crime, testing theory, policy, and prediction Clearly and accessibly written by leading scholars in the field as well as up-and-coming scholars
Susan Fox The Wife He Chose Susan Fox The Wife He Chose Новинка

Susan Fox The Wife He Chose

116.67 руб.
Cade Chalmers knew he was playing with fire by attempting to live under the same roof as Colleen. But he was desperate: Cade needed to share custody of his orphaned niece and nephew with her. The trouble was, each time he was alone with Colleen for even a minute, they clashed…It wasn't just antagonism–it was explosive attraction. Cade decided he simply had to bite the bullet–the best thing for the children would be for him and Colleen to marry. It was a purely common-sense proposal, but the result was fireworks!
Ashraf Ayoub Handbook of Orthognathic Treatment. A Team Approach Ashraf Ayoub Handbook of Orthognathic Treatment. A Team Approach Новинка

Ashraf Ayoub Handbook of Orthognathic Treatment. A Team Approach

7197.23 руб.
This handbook provides a short, contemporary text on the management of dentofacial deformities. The importance of a well organised, inter-disciplinary approach is emphasised throughout and the following key areas are presented: A detailed account of the role of the psychologist, from initial assessment through to post-operative support. A systematic approach to dentofacial assessment, including a section on diagnostic records and an overview of cephalometry. A logical step-by-step approach to treatment planning, emphasising the interactive thought process required when setting orthodontic and surgical objectives. The fundamentals of surgical orthodontics, with the scope and limitations of orthodontic appliances clearly explained for each phase of treatment. A description of orthognathic technical procedures and how potential errors can be minimised in order to improve the accuracy of model surgery. An account of how to carry out photo-cephalometric profile prediction planning, including a critique of the method. A detailed description of the full range of mandibular and maxillary orthognathic surgical procedures, including indications and complications. A chapter on higher-level osteotomies for the treatment of more severe craniofacial abnormalities is included for completeness. A series of six contrasting case studies. There is an emphasis on the technological advances that are rapidly enabling the global paradigm shift from 2D to 3D planning.
Hugo Kubinyi Protein-Protein Interactions in Drug Discovery Hugo Kubinyi Protein-Protein Interactions in Drug Discovery Новинка

Hugo Kubinyi Protein-Protein Interactions in Drug Discovery

15746.13 руб.
Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the development pipeline of major pharmaceutical companies to illustrate the power and potential of this approach. From the contents: * Prediction of intra- and inter-species protein-protein interactions facilitating systems biology studies * Modulators of protein-protein interactions: The importance of Three-Dimensionality * Interactive technologies for leveraging the known chemistry of anchor residues * SH3 Domains as Drug Targets * P53 MDM2 Antagonists: Towards Non Genotoxic Anticancer Treatments * Inhibition of LFA-1/ICAM interaction for treatment of autoimmune diseases * The PIF-binding pocket of AGC kinases * Peptidic inhibitors of protein-protein interactions for cell adhesion receptors * The REPLACE Strategy for generating Non-ATP competitive Inhibitors of Cell-Cycle Protein Kinases and more
Mark Robinson Progress in Modern Hydrology. Past, Present and Future Mark Robinson Progress in Modern Hydrology. Past, Present and Future Новинка

Mark Robinson Progress in Modern Hydrology. Past, Present and Future

11243.68 руб.
Hydrology is vital to human civilisations as well as to natural ecosystems, yet it has only emerged as a distinct scientific discipline during the last 50 years or so. This book reviews the development of modern hydrology primarily through the experiences of the multidisciplinary team of scientists and engineers at Wallingford, near Oxford, who have been at the forefront of many of the developments in UK hydrological research. These topics include: • The development of basic understanding through the collection of data with specialised instrumentation in experimental basins • The study of extreme flows – both floods and droughts • The role moisture in the soil • Studies of the processes controlling evaporation • Water resource studies • Modelling and prediction of the extremes of flow improved • Understanding of water quality issues • A widening recognition of the importance of an ecosystem approach • Meeting the challenges of climate change, • Data handling • Future developments in hydrology and the pressures which generate them. Readership: hydrologists in both academia and a wide range of applied fields such as civil engineering, meteorology, geography and physics, as well as advanced students in earth science, environmental science and physical geography programmes worldwide.
Sadoon Morad Linking Diagenesis to Sequence Stratigraphy (Special Publication 45 of the IAS) Sadoon Morad Linking Diagenesis to Sequence Stratigraphy (Special Publication 45 of the IAS) Новинка

Sadoon Morad Linking Diagenesis to Sequence Stratigraphy (Special Publication 45 of the IAS)

11993.49 руб.
Sequence stratigraphy is a powerful tool for the prediction of depositional porosity and permeability, but does not account for the impact of diagenesis on these reservoir parameters. Therefore, integrating diagenesis and sequence stratigraphy can provide a better way of predicting reservoir quality. This special publication consists of 19 papers (reviews and case studies) exploring different aspects of the integration of diagenesis and sequence stratigraphy in carbonate, siliciclastic, and mixed carbonate-siliciclastic successions from various geological settings. This book will be of interest to sedimentary petrologists aiming to understand the distribution of diagenesis in siliciclastic and carbonate successions, to sequence stratigraphers who can use diagenetic features to recognize and verify interpreted key stratigraphic surfaces, and to petroleum geologists who wish to develop more realistic conceptual models for the spatial and temporal distribution of reservoir quality. This book is part of the International Association of Sedimentologists (IAS) Special Publications. The Special Publications from the IAS are a set of thematic volumes edited by specialists on subjects of central interest to sedimentologists. Papers are reviewed and printed to the same high standards as those published in the journal Sedimentology and several of these volumes have become standard works of reference.
Andrew Wereszczak Corrosion, Wear, Fatigue, and Reliability of Ceramics Andrew Wereszczak Corrosion, Wear, Fatigue, and Reliability of Ceramics Новинка

Andrew Wereszczak Corrosion, Wear, Fatigue, and Reliability of Ceramics

7720.11 руб.
This volume provides a one-stop resource, compiling current research on the behavior and reliability of ceramic macro and micro scale systems. It is a collection of papers from The American Ceramic Society s 32nd International Conference on Advanced Ceramics and Composites, January 27-February 1, 2008. Topics include Design and Testing Challenges for Ceramic Joints; Structural Design, Testing and Life Prediction of Monolithic and Composite Components; Mechanical Behavior, Design, and Reliability of Small Scale Systems; Environmental Effects on Mechanical Properties; and more. This is a valuable reference for researchers in ceramics engineering.
Gerhard Wagner Product Design and Engineering. Formulation of Gels and Pastes Gerhard Wagner Product Design and Engineering. Formulation of Gels and Pastes Новинка

Gerhard Wagner Product Design and Engineering. Formulation of Gels and Pastes

14021.69 руб.
Covering the whole value chain – from product requirements and properties via process technologies and equipment to real-world applications – this reference represents a comprehensive overview of the topic. The editors and majority of the authors are members of the European Federation of Chemical Engineering, with backgrounds from academia as well as industry. Therefore, this multifaceted area is highlighted from different angles: essential physico-chemical background, latest measurement and prediction techniques, and numerous applications from cosmetic up to food industry. Recommended reading for process, pharma and chemical engineers, chemists in industry, and those working in the pharmaceutical, food, cosmetics, dyes and pigments industries.

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A step-by-step introduction to modeling, training, and forecasting using wavelet networks Wavelet Neural Networks: With Applications in Financial Engineering, Chaos, and Classification presents the statistical model identification framework that is needed to successfully apply wavelet networks as well as extensive comparisons of alternate methods. Providing a concise and rigorous treatment for constructing optimal wavelet networks, the book links mathematical aspects of wavelet network construction to statistical modeling and forecasting applications in areas such as finance, chaos, and classification. The authors ensure that readers obtain a complete understanding of model identification by providing in-depth coverage of both model selection and variable significance testing. Featuring an accessible approach with introductory coverage of the basic principles of wavelet analysis, Wavelet Neural Networks: With Applications in Financial Engineering, Chaos, and Classification also includes: • Methods that can be easily implemented or adapted by researchers, academics, and professionals in identification and modeling for complex nonlinear systems and artificial intelligence • Multiple examples and thoroughly explained procedures with numerous applications ranging from financial modeling and financial engineering, time series prediction and construction of confidence and prediction intervals, and classification and chaotic time series prediction • An extensive introduction to neural networks that begins with regression models and builds to more complex frameworks • Coverage of both the variable selection algorithm and the model selection algorithm for wavelet networks in addition to methods for constructing confidence and prediction intervals Ideal as a textbook for MBA and graduate-level courses in applied neural network modeling, artificial intelligence, advanced data analysis, time series, and forecasting in financial engineering, the book is also useful as a supplement for courses in informatics, identification and modeling for complex nonlinear systems, and computational finance. In addition, the book serves as a valuable reference for researchers and practitioners in the fields of mathematical modeling, engineering, artificial intelligence, decision science, neural networks, and finance and economics.
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