rna interference rnai mediated tomato leaf curl virus gene silencing



Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Новинка

Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi

15602.85 руб. или Купить в рассрочку!
RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: Mechanisms, Barriers, and Analysis of RNAi Delivery Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective Bioconjugation of siRNA for Site Specifi c Delivery Nanoscale Delivery Systems for RNAi Environmentally-Responsive Delivery Systems for RNAi Light-sensitive RNAi Viral-Mediated Delivery of shRNA and miRNA RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease miRNA as therapeutic agents and targets Advanced Delivery and Therapeutic Applications of RNAi combines the essential aspects of developing RNAi therapeutics from bench to clinic, and is invaluable for researchers working on RNAi, drug discovery and delivery, biomedical engineering, biomaterials, molecular biology, and biotechnology.
Jane Wu Post-Transcriptional Gene Regulation. RNA Processing in Eukaryotes Jane Wu Post-Transcriptional Gene Regulation. RNA Processing in Eukaryotes Новинка

Jane Wu Post-Transcriptional Gene Regulation. RNA Processing in Eukaryotes

2107.27 руб. или Купить в рассрочку!
Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry.
Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Новинка

Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development

10479.81 руб. или Купить в рассрочку!
RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.
Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Новинка

Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives

12275.7 руб. или Купить в рассрочку!
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
Chowdhury Sushovan, Singh Sanjeev, Sarkhel B. C. Gene Silencing in Goat - A New Way to Increase Chevon Production Chowdhury Sushovan, Singh Sanjeev, Sarkhel B. C. Gene Silencing in Goat - A New Way to Increase Chevon Production Новинка

Chowdhury Sushovan, Singh Sanjeev, Sarkhel B. C. Gene Silencing in Goat - A New Way to Increase Chevon Production

In vitro gene silencing by RNA interference technology is still a new concept, especially in the field of animal biotechnology or agriculturally important small ruminants like sheep and goat. This is the first time the authors reported an efficient and robust way of knocking down the Myostatin gene (knocking down of which will increase the muscle mass/meat) in Caprine fibroblast cell by using U6 promoter based vector and with four different 29 nucleotide shRNA combinations. An easy and effective technique of measuring the transfection efficiency of short hairpin DNA containing plasmids has also been documented. Two, out of four shRNAs are proved to be very efficient and they can be used in vivo for confirmation of the knockdown effect in living animal, as well as for production of a stably transfected cell line with "knocked down MSTN" for future research in this field. Hence, this work is an important contribution in Animal-Cell Biotechnology. An elaborate review of relevant literature and a step-by-step methodical explanation of the experiment with minute details are the extra assets of this book.
Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives Новинка

Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives

12436.29 руб. или Купить в рассрочку!
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

14288.7 руб. или Купить в рассрочку!
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

14475.71 руб. или Купить в рассрочку!
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Abdelaleim ElSayed, Ewald Komor Sugarcane Yellow Leaf Virus Abdelaleim ElSayed, Ewald Komor Sugarcane Yellow Leaf Virus Новинка

Abdelaleim ElSayed, Ewald Komor Sugarcane Yellow Leaf Virus

Sugarcane is an important crop plant and has served as a source of sugar for hundreds of years, recently it is used to produce bioethanol, a renewable bio-fuel energy source. Sugarcane yellow leaf virus (SCYLV) was detected in the late 1990s first in Hawaii as a causal agent of a sugarcane disease (Yellow leaf) which leads to sugarcane yellow leaf syndrome and reduced sugar yield and later in many sugarcane regions of the world. The virus particles were observed in the cytoplasm of phloem companion cells of sugarcane. Viral infection often affects carbon assimilation and metabolism in host plants. Todays analysis revealed that SCYLV belongs to polerovirus which is a member of the luteoviridae family and has a apparently arisen through recombination between a Polerovirus, a Luteovirus and an Enamovirus. It is a +ssRNA-virus whose sequence contains 6 open reading frames.
Liaqat Ali, Inam Ullah, Wesal Ahmad Molecular Study of Wheat for Lr26 Gene Liaqat Ali, Inam Ullah, Wesal Ahmad Molecular Study of Wheat for Lr26 Gene Новинка

Liaqat Ali, Inam Ullah, Wesal Ahmad Molecular Study of Wheat for Lr26 Gene

leaf rust is a wheat disease and the wheat varieties which having leaf rust genes are resistant to it. Lr26 is also a leaf rust resistant gene found in various wheat varieties, having size of 1000 bps. The wheat varieties studied in this research was collected from various locations of Pakistan and observed that those varieties among the collected having Lr26 gene were not only resistant to the disease but also high in yield production and good in other morphological characters.
Arlie Zegarra Pumapillo Nukleinsauren, Konzentration einer DNA-, RNA- und Proteinstocklosung. Ein Praktikumsprotokoll Arlie Zegarra Pumapillo Nukleinsauren, Konzentration einer DNA-, RNA- und Proteinstocklosung. Ein Praktikumsprotokoll Новинка

Arlie Zegarra Pumapillo Nukleinsauren, Konzentration einer DNA-, RNA- und Proteinstocklosung. Ein Praktikumsprotokoll

Praktikumsbericht / -arbeit aus dem Jahr 2008 im Fachbereich Biologie - Mikrobiologie, Molekularbiologie, Note: 2,3, Ruprecht-Karls-Universität Heidelberg (Fakultät für Biowissenschaften), Veranstaltung: Hauptpraktikum E1: Nukleinsäuren, Sprache: Deutsch, Abstract: Ziel des Versuches ist es, die Konzentration einer DNA-, RNA- und Proteinstocklösung durch Photometrie zu bestimmen. Außerdem soll noch die Reinheit ausgerechnet werden.Inhalt:Konzentrationsbestimmung von DNA-, RNA- und Proteinlösungen VersuchsabsichtMaterialien und MethodenErgebnisse & FragenDiskussionPlasmididentifizierung: Grundlegende molekularbiologische Methoden VersuchsabsichtMaterialien und MethodenErgebnisseDiskussion & FragenKlonierung von GFP in E. coli VersuchsabsichtMaterialien und MethodenErgebnisseDiskussion & FragenRetrovirale Transduktion von CHO-Zellen VersuchsabsichtMaterialien und MethodenErgebnisseDiskussion & FragencDNA-Produktion aus mRNA von HeLa-Zellen und Klonierung in E.coli VersuchsabsichtMaterialien und MethodenErgebnisseDiskussion & FragenRNA-Interference mittels siRNA in HeLa-ZellenVersuchsabsichtMaterialien und MethodenErgebnisseDiskussion & FragenAnhang
Li-He Zhang Medicinal Chemistry of Nucleic Acids Li-He Zhang Medicinal Chemistry of Nucleic Acids Новинка

Li-He Zhang Medicinal Chemistry of Nucleic Acids

12721.93 руб. или Купить в рассрочку!
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids presents a thorough overview of nucleic acid chemistry—a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids—such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs—to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy. Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes: In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry A close look at a large range of current topics on nucleic acid chemistry and biology Essential information on the use of nucleic acid drugs to treat diseases like cancer A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research area Thorough in its approach and promising in its message, Medicinal Chemistry of Nucleic Acids probes the new domains of pharmaceutical research—and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.
Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors Новинка

Mien-Chie Hung Cancer Gene Therapy by Viral and Non-viral Vectors

11531.5 руб. или Купить в рассрочку!
Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.
Jo Malone Green Tomato Leaf Home Candle Jo Malone Green Tomato Leaf Home Candle Новинка

Jo Malone Green Tomato Leaf Home Candle

Выращенные с теплице томаты. Землистые, с обильной листвой и наполненные солнцем. Хруст сочных зеленых стеблей гальбанума. Оживленый запахом артемезии, с нотами черной смородиной, с добавлением мягкости мха. Резкий, но запоминающийся.
Босоножки Gene Gene GE632AWEMIQ8 Босоножки Gene Gene GE632AWEMIQ8 Новинка

Босоножки Gene Gene GE632AWEMIQ8

Босоножки Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сандалии Gene Gene GE632AWEMIT4 Сандалии Gene Gene GE632AWEMIT4 Новинка

Сандалии Gene Gene GE632AWEMIT4

Сандалии Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIU8 Туфли Gene Gene GE632AWEMIU8 Новинка

Туфли Gene Gene GE632AWEMIU8

Туфли Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIR4 Босоножки Gene Gene GE632AWEMIR4 Новинка

Босоножки Gene Gene GE632AWEMIR4

Босоножки Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIU6 Туфли Gene Gene GE632AWEMIU6 Новинка

Туфли Gene Gene GE632AWEMIU6

Туфли Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Лоферы Gene Gene GE632AWEMIS3 Лоферы Gene Gene GE632AWEMIS3 Новинка

Лоферы Gene Gene GE632AWEMIS3

Лоферы Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Ботильоны Gene Gene GE632AWEMIU4 Ботильоны Gene Gene GE632AWEMIU4 Новинка

Ботильоны Gene Gene GE632AWEMIU4

Ботильоны Gene. Цвет: черный. Материал: искусственная кожа, текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Балетки Gene Gene GE632AWAURS1 Балетки Gene Gene GE632AWAURS1 Новинка

Балетки Gene Gene GE632AWAURS1

Балетки Gene. Цвет: синий. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Полусапоги Gene Gene GE632AWCMWR3 Полусапоги Gene Gene GE632AWCMWR3 Новинка

Полусапоги Gene Gene GE632AWCMWR3

Полусапоги Gene. Цвет: черный. Материал: искусственный велюр, искусственный мех.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda.
Сандалии Gene Gene GE632AWEMIT5 Сандалии Gene Gene GE632AWEMIT5 Новинка

Сандалии Gene Gene GE632AWEMIT5

Сандалии Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIU1 Туфли Gene Gene GE632AWEMIU1 Новинка

Туфли Gene Gene GE632AWEMIU1

Туфли Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIR0 Босоножки Gene Gene GE632AWEMIR0 Новинка

Босоножки Gene Gene GE632AWEMIR0

Босоножки Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIU9 Туфли Gene Gene GE632AWEMIU9 Новинка

Туфли Gene Gene GE632AWEMIU9

Туфли Gene. Цвет: розовый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Ботинки Gene Gene GE632AWEMIR7 Ботинки Gene Gene GE632AWEMIR7 Новинка

Ботинки Gene Gene GE632AWEMIR7

Ботинки Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Кроссовки Gene Gene GE632AWEMIS1 Кроссовки Gene Gene GE632AWEMIS1 Новинка

Кроссовки Gene Gene GE632AWEMIS1

Кроссовки Gene. Цвет: розовый. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIS8 Сабо Gene Gene GE632AWEMIS8 Новинка

Сабо Gene Gene GE632AWEMIS8

Сабо Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIQ7 Босоножки Gene Gene GE632AWEMIQ7 Новинка

Босоножки Gene Gene GE632AWEMIQ7

Босоножки Gene. Цвет: фиолетовый. Материал: искусственная замша.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сандалии Gene Gene GE632AWEMIT6 Сандалии Gene Gene GE632AWEMIT6 Новинка

Сандалии Gene Gene GE632AWEMIT6

Сандалии Gene. Цвет: серебряный. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIS7 Сабо Gene Gene GE632AWEMIS7 Новинка

Сабо Gene Gene GE632AWEMIS7

Сабо Gene. Цвет: черный. Материал: искусственная замша.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIS9 Сабо Gene Gene GE632AWEMIS9 Новинка

Сабо Gene Gene GE632AWEMIS9

Сабо Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIV1 Туфли Gene Gene GE632AWEMIV1 Новинка

Туфли Gene Gene GE632AWEMIV1

Туфли Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Лоферы Gene Gene GE632AWEMIS4 Лоферы Gene Gene GE632AWEMIS4 Новинка

Лоферы Gene Gene GE632AWEMIS4

Лоферы Gene. Цвет: серый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Кроссовки Gene Gene GE632AWEMIS0 Кроссовки Gene Gene GE632AWEMIS0 Новинка

Кроссовки Gene Gene GE632AWEMIS0

Кроссовки Gene. Цвет: серый. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Лоферы Gene Gene GE632AWEMIS5 Лоферы Gene Gene GE632AWEMIS5 Новинка

Лоферы Gene Gene GE632AWEMIS5

Лоферы Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWCMWR8 Туфли Gene Gene GE632AWCMWR8 Новинка

Туфли Gene Gene GE632AWCMWR8

Туфли Gene. Цвет: черный. Материал: искусственная лаковая кожа.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIT1 Сабо Gene Gene GE632AWEMIT1 Новинка

Сабо Gene Gene GE632AWEMIT1

Сабо Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сандалии Gene Gene GE632AWEMIT9 Сандалии Gene Gene GE632AWEMIT9 Новинка

Сандалии Gene Gene GE632AWEMIT9

Сандалии Gene. Цвет: белый. Материал: искусственная кожа, текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIR2 Босоножки Gene Gene GE632AWEMIR2 Новинка

Босоножки Gene Gene GE632AWEMIR2

Босоножки Gene. Цвет: белый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIT0 Сабо Gene Gene GE632AWEMIT0 Новинка

Сабо Gene Gene GE632AWEMIT0

Сабо Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Слипоны Gene Gene GE632AWEMIU0 Слипоны Gene Gene GE632AWEMIU0 Новинка

Слипоны Gene Gene GE632AWEMIU0

Слипоны Gene. Цвет: черный. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIT3 Босоножки Gene Gene GE632AWEMIT3 Новинка

Босоножки Gene Gene GE632AWEMIT3

Босоножки Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIR5 Босоножки Gene Gene GE632AWEMIR5 Новинка

Босоножки Gene Gene GE632AWEMIR5

Босоножки Gene. Цвет: серый. Материал: искусственная замша.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIU7 Туфли Gene Gene GE632AWEMIU7 Новинка

Туфли Gene Gene GE632AWEMIU7

Туфли Gene. Цвет: бежевый. Материал: искусственная лаковая кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Лоферы Gene Gene GE632AWEMIS2 Лоферы Gene Gene GE632AWEMIS2 Новинка

Лоферы Gene Gene GE632AWEMIS2

Лоферы Gene. Цвет: серый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWAURT3 Босоножки Gene Gene GE632AWAURT3 Новинка

Босоножки Gene Gene GE632AWAURT3

Босоножки Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2018. С бесплатной доставкой и примеркой на Lamoda.
Дутики Gene Gene GE632AWCMWQ1 Дутики Gene Gene GE632AWCMWQ1 Новинка

Дутики Gene Gene GE632AWCMWQ1

Дутики Gene. Цвет: черный. Материал: искусственная кожа, текстиль.Сезон: Осень-зима 2018/2019. С бесплатной доставкой и примеркой на Lamoda.
Printio Killer tomato Printio Killer tomato Новинка

Printio Killer tomato

Футболка с полной запечаткой (мужская) — пол: МУЖ, материал: СИНТЕТИКА.
Туфли Gene Gene GE632AWEMIU2 Туфли Gene Gene GE632AWEMIU2 Новинка

Туфли Gene Gene GE632AWEMIU2

Туфли Gene. Цвет: бежевый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIQ9 Босоножки Gene Gene GE632AWEMIQ9 Новинка

Босоножки Gene Gene GE632AWEMIQ9

Босоножки Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIT2 Сабо Gene Gene GE632AWEMIT2 Новинка

Сабо Gene Gene GE632AWEMIT2

Сабо Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Босоножки Gene Gene GE632AWEMIR3 Босоножки Gene Gene GE632AWEMIR3 Новинка

Босоножки Gene Gene GE632AWEMIR3

Босоножки Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIU3 Туфли Gene Gene GE632AWEMIU3 Новинка

Туфли Gene Gene GE632AWEMIU3

Туфли Gene. Цвет: розовый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сабо Gene Gene GE632AWEMIS6 Сабо Gene Gene GE632AWEMIS6 Новинка

Сабо Gene Gene GE632AWEMIS6

Сабо Gene. Цвет: черный. Материал: искусственный велюр.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Кроссовки Gene Gene GE632AWEMIR8 Кроссовки Gene Gene GE632AWEMIR8 Новинка

Кроссовки Gene Gene GE632AWEMIR8

Кроссовки Gene. Цвет: коричневый. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Сандалии Gene Gene GE632AWEMIT7 Сандалии Gene Gene GE632AWEMIT7 Новинка

Сандалии Gene Gene GE632AWEMIT7

Сандалии Gene. Цвет: золотой. Материал: текстиль.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.
Туфли Gene Gene GE632AWEMIV0 Туфли Gene Gene GE632AWEMIV0 Новинка

Туфли Gene Gene GE632AWEMIV0

Туфли Gene. Цвет: черный. Материал: искусственная кожа.Сезон: Весна-лето 2019. С бесплатной доставкой и примеркой на Lamoda.

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Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.
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