synthesis biological investigation of fluorinated amino acid analogs



Peter Langer Asymmetric Synthesis of Non-Proteinogenic Amino Acids Peter Langer Asymmetric Synthesis of Non-Proteinogenic Amino Acids Новинка

Peter Langer Asymmetric Synthesis of Non-Proteinogenic Amino Acids

14755.94 руб.
Authored by two internationally recognized experts with an excellent track record, this much-needed reference summarizes latest research in the rapidly developing field of stereoselective synthesis of enantiomerically enriched amino acids, particularly of non-proteinogenic origin. It highlights several different catalytic and stoichiometric asymmetric methods for their synthesis and also provides information on origin, biological properties, different synthetic strategies and important applications in medicine and pharmacology. Essential reading for synthetic chemists working in the field of asymmetric synthesis, natural products and peptide synthesis, stereochemistry, medicinal chemistry, biochemistry, pharmacology, and biotechnology.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

16983.49 руб.
This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry

16483.74 руб.
This is the third of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides This third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purification and automation. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry

16983.49 руб.
This is the third of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides This third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purification and automation. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

14239.43 руб.
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

13820.33 руб.
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides

16983.49 руб.
This is the last of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides Volume 5 of this series presents a wealth of methods to analyze amino acids and peptides. Classical approaches are described, such as X-ray analysis, chromatographic methods, NMR, AFM, mass spectrometry and 2D-gel electrophoresis, as well as newer approaches, including Surface Plasmon Resonance and array technologies. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry Новинка

Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry

12237.01 руб.
A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery.
David A. Bender Amino Acid Metabolism David A. Bender Amino Acid Metabolism Новинка

David A. Bender Amino Acid Metabolism

10601.7 руб.
Amino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the incorporation of inorganic nitrogen into amino acids, the book then details other major nitrogenous compounds in micro-organisms, plants and animals. Contents include a discussion of the catabolism of amino acids and other nitrogenous compounds in animals, and the microbiological reactions involved in release of nitrogen gas back into the atmosphere. Mammalian (mainly human) protein and amino acid requirements are considered in detail, and the methods that are used to determine them. Chapters consider individual amino acids, grouped according to their metabolic origin, and discussing their biosynthesis (in plants and micro-organisms for those that are dietary essentials for human beings), major metabolic roles (mainly in human metabolism) and catabolism (again mainly in human metabolism). There is also discussion of regulatory mechanisms for all these metabolic pathways, and of metabolic and genetic diseases affecting the (human) metabolism of amino acids. Throughout the book the emphasis is on the nutritional importance of amino acids, integration and control of metabolism and metabolic and other disturbances of relevance to human biochemistry and health. Completely revised edition of this comprehensive text covering all the latest findings in amino acid metabolism research Written by an authority in the field Covers new advances in structural biology Clear illustrations of all structures and metabolic pathways Full list of recommended further reading for each chapter and bibliography of papers cited in the text
Felix Polyak Hyaluronic Acid. Production, Properties, Application in Biology and Medicine Felix Polyak Hyaluronic Acid. Production, Properties, Application in Biology and Medicine Новинка

Felix Polyak Hyaluronic Acid. Production, Properties, Application in Biology and Medicine

11517.51 руб.
Hyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process. Hyaluronic Acid: Production, Properties, Application in Biology and Medicine consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 describes the methods to manufacture and purify hyaluronic acid, including the analytical means for assessing quality of the finished product. Chapter 4 discusses the structure and rheological properties of hyaluronic acid considering effects on conformation and biological properties related to molecular weight. In Chapter 5, the physical and chemical methods for modifying the structure of hyaluronan are discussed including cross-linking using bi-functional reagents, solid-phase modification and effects of the combined action of high pressures and shift deformation. The final chapter focuses on the products derived from hyaluronic acid, including therapeutics composed of modified hyaluronan conjugated to vitamins, amino acids and oligo-peptides. The biological roles and medical applications of this polysaccharide have been extensively studied and this book provides a wealth of scientific data demonstrating the critical role of hyaluronic acid and its promise as a multifaceted bio-macromolecule. Approaching hyaluronic acid from multiple angles, this book links relationships between its biological functions, structure and physical–chemical properties. It will be an invaluable resource to researchers, both industrial and academic, involved in all aspects of hyaluronan-based technologies.
Ari M. P. Koskinen Asymmetric Synthesis of Natural Products Ari M. P. Koskinen Asymmetric Synthesis of Natural Products Новинка

Ari M. P. Koskinen Asymmetric Synthesis of Natural Products

12607.83 руб.
Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. This is followed by chapters on each of the major individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikamic acid derivatives and alkaloids. For this second edition the text has been thoroughly updated and expanded, and includes new discussions and examples covering atom and redox economies, practical aspects and environmental awareness. Organocatalysis has emerged completely in the last ten years, and has been fully integrated into this new edition.
Rokita Steven E. Oxidation of Amino Acids, Peptides, and Proteins. Kinetics and Mechanism Rokita Steven E. Oxidation of Amino Acids, Peptides, and Proteins. Kinetics and Mechanism Новинка

Rokita Steven E. Oxidation of Amino Acids, Peptides, and Proteins. Kinetics and Mechanism

11124.56 руб.
Explains the role of reactive intermediates in biological systems as well as in environmental remediation With its clear and systematic approach, this book examined the broad range of reactive intermediate that can be generated in biological environments, detailing the fundamental properties of each reactive intermediate. Readers gain a contemporary understanding of how these intermediates react with different compounds, with an emphasis on amino acids, peptides, and proteins. The author not only sets forth the basic chemistry and nature of reactive intermediates, he also demonstrates how the properties of the intermediates presented in the book compare with each other. Oxidation of Amino Acids, Peptides, and Proteins begins with a discussion of radical and non-radical reactive species as well as an exploration of the significance of reactive species in the atmosphere, disinfection processes, and environmental remediation. Next, the book covers such topics as: Thermodynamics of amino acids and reactive species and the effect of metal-ligand binding in oxidation chemistry Kinetics and mechanisms of reactive halogen, oxygen, nitrogen, carbon, sulfur and phosphate species as well as reactive high-valent Cr, Mn, and Fe species Reactivity of the species with molecules of biological and environmental importance Generation of reactive species in the laboratory for kinetics studies Oxidation of amino acids, peptides, and proteins by permanganate, ferryl, and ferrate species Application of reactive species in purifying water and treating wastewater With this book as their guide, readers will be able to assess the overall effects of reactive intermediates in biological environments. Moreover, they’ll learn how to apply this knowledge for successful water purification and wastewater treatment.
Wang Binghe Carbohydrate Recognition. Biological Problems, Methods, and Applications Wang Binghe Carbohydrate Recognition. Biological Problems, Methods, and Applications Новинка

Wang Binghe Carbohydrate Recognition. Biological Problems, Methods, and Applications

11569.54 руб.
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Mourad Elloumi Biological Knowledge Discovery Handbook. Preprocessing, Mining and Postprocessing of Biological Data Mourad Elloumi Biological Knowledge Discovery Handbook. Preprocessing, Mining and Postprocessing of Biological Data Новинка

Mourad Elloumi Biological Knowledge Discovery Handbook. Preprocessing, Mining and Postprocessing of Biological Data

13460.43 руб.
The first comprehensive overview of preprocessing, mining, and postprocessing of biological data Molecular biology is undergoing exponential growth in both the volume and complexity of biological data—and knowledge discovery offers the capacity to automate complex search and data analysis tasks. This book presents a vast overview of the most recent developments on techniques and approaches in the field of biological knowledge discovery and data mining (KDD)—providing in-depth fundamental and technical field information on the most important topics encountered. Written by top experts, Biological Knowledge Discovery Handbook: Preprocessing, Mining, and Postprocessing of Biological Data covers the three main phases of knowledge discovery (data preprocessing, data processing—also known as data mining—and data postprocessing) and analyzes both verification systems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological Data Mining Combining sound theory with practical applications in molecular biology, Biological Knowledge Discovery Handbook is ideal for courses in bioinformatics and biological KDD as well as for practitioners and professional researchers in computer science, life science, and mathematics.
Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Новинка

Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators

12236.63 руб.
Many small molecules occur naturally as «messenger» chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers in helping develop our understanding of biological function and in the development of new drugs. However extracting them from nature can be prohibitively expensive, so there is great interest in devising methods of synthesising them from simple starting materials in the laboratory. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to the techniques and strategies for the synthesis of biofunctional small molecules. Topics include: what are biofunctional molecules? why must biofunctional molecules be synthesized? how can we synthesize biofunctional molecules? the synthesis of phytohormones, phytoalexins and other biofunctional molecules of plant origin the synthesis of insect juvenile hormones and antifeedants the synthesis of pheromones and the significance of chirality in pheromone science the synthesis of microbial hormones and pheromones, antibiotics, and other biofunctional molecules of microbial origin the synthesis of marine antifeedants and medicinal candidates a synthetic examination of incorrectly proposed structures of biomolecules reflections on science as a human endeavor Drawing on a career of almost 50 years researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished chemical career.
Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Новинка

Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators

12607.83 руб.
Many small molecules occur naturally as «messenger» chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers in helping develop our understanding of biological function and in the development of new drugs. However extracting them from nature can be prohibitively expensive, so there is great interest in devising methods of synthesising them from simple starting materials in the laboratory. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to the techniques and strategies for the synthesis of biofunctional small molecules. Topics include: what are biofunctional molecules? why must biofunctional molecules be synthesized? how can we synthesize biofunctional molecules? the synthesis of phytohormones, phytoalexins and other biofunctional molecules of plant origin the synthesis of insect juvenile hormones and antifeedants the synthesis of pheromones and the significance of chirality in pheromone science the synthesis of microbial hormones and pheromones, antibiotics, and other biofunctional molecules of microbial origin the synthesis of marine antifeedants and medicinal candidates a synthetic examination of incorrectly proposed structures of biomolecules reflections on science as a human endeavor Drawing on a career of almost 50 years researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished chemical career.
Marcus Wilhelmsson Fluorescent Analogs of Biomolecular Building Blocks. Design and Applications Marcus Wilhelmsson Fluorescent Analogs of Biomolecular Building Blocks. Design and Applications Новинка

Marcus Wilhelmsson Fluorescent Analogs of Biomolecular Building Blocks. Design and Applications

12596.53 руб.
Fluorescent Biomolecules and their Building Blocks focuses on the design of fluorescent probes for the four major families of macromolecular building blocks. Compiling the expertise of multiple authors, this book moves from introductory chapters to an exploration of the design, synthesis, and implementation of new fluorescent analogues of biomolecular building blocks, including examples of small-molecule fluorophores and sensors that are part of biomolecular assemblies.
Wolf-Dieter Fessner Cascade Biocatalysis. Integrating Stereoselective and Environmentally Friendly Reactions Wolf-Dieter Fessner Cascade Biocatalysis. Integrating Stereoselective and Environmentally Friendly Reactions Новинка

Wolf-Dieter Fessner Cascade Biocatalysis. Integrating Stereoselective and Environmentally Friendly Reactions

15259.94 руб.
This ready reference presents environmentally friendly and stereoselective methods of modern biocatalysis. The experienced and renowned team of editors have gathered top international authors for this book. They cover such emerging topics as chemoenzymatic methods and multistep enzymatic reactions, while showing how these novel methods and concepts can be used for practical applications. Multidisciplinary topics, including directed evolution, dynamic kinetic resolution, and continuous-flow methodology are also discussed. From the contents: * Directed Evolution of Ligninolytic Oxidoreductases: from Functional Expression to Stabilization and Beyond * New Trends in the In Situ Enzymatic Recycling of NAD(P)(H) Cofactors * Monooxygenase-Catalyzed Redox Cascade Biotransformations * Biocatalytic Redox Cascades Involving w-Transaminases * Multi-Enzyme Systems and Cascade Reactions Involving Cytochrome P450 Monooxygenases * Chemo-Enzymatic Cascade Reactions for the Synthesis of Glycoconjugates * Synergies of Chemistry and Biochemistry for the Production of Beta-Amino Acids * Racemizable Acyl Donors for Enzymatic Dynamic Kinetic Resolution * Stereoselective Hydrolase-Catalyzed Processes in Continuous-Flow Mode * Perspectives on Multienzyme Process Technology * Nitrile Converting Enzymes Involved in Natural and Synthetic Cascade Reactions * Mining Genomes for Nitrilases * Key-Study on the Kinetic Aspects of the In-Situ NHase/AMase Cascade System of M. imperiale Resting Cells for Nitrile Bioconversion * Enzymatic Stereoselective Synthesis of Beta-Amino Acids * New Applications of Transketolase: Cascade Reactions for Assay Development * Aldolases as Catalyst for the Synthesis of Carbohydrates and Analogs * Enzymatic Generation of Sialoconjugate Diversity * Methyltransferases in Biocatalysis * Chemoenzymatic Multistep One-Pot Processes
Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids Новинка

Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids

16612.67 руб.
Functionalized Inorganic Fluorides: Synthesis, Characterization & Properties of Nanostructured Solids covers several classes of nanostructured and functionalized inorganic fluorides, oxide-fluorides, and fluorinated oxides such as silica and alumina. Ranging from powders or glass-ceramics to thin layers and coatings, they have applications as more efficient and less aggressive catalysts, UV absorbers, planar optical waveguides, integrated lasers and optical amplifiers, luminescent materials, anti-reflective coatings and high Tc superconductors. With a focus on new types of solids, such as nanopowders, hybrids, mesoporous fluorides, and intercalation compounds, the book covers new synthesis routes; physical-chemical characterizations – including morphology, structure, spectroscopic and optical behaviour; detailed ab initio investigations and simulations; and -last but not least- potential applications.
Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology Новинка

Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

11517.51 руб.
Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.
Armando Cordova Catalytic Asymmetric Conjugate Reactions Armando Cordova Catalytic Asymmetric Conjugate Reactions Новинка

Armando Cordova Catalytic Asymmetric Conjugate Reactions

16241.85 руб.
This unique and long-awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conjugate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P-N ligands, organocatalysis, domino reactions, Lewis acid and base catalysis. There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules. With its reliable and previously unpublished experimental procedures, this is a true source of high quality information.
Lam Yulin Solid-Phase Organic Synthesis. Concepts, Strategies, and Applications Lam Yulin Solid-Phase Organic Synthesis. Concepts, Strategies, and Applications Новинка

Lam Yulin Solid-Phase Organic Synthesis. Concepts, Strategies, and Applications

11569.54 руб.
Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesis With its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers everything needed to conduct their own state-of-the-art science experiments. Featuring chapters written by leading researchers in the field, Solid-Phase Organic Synthesis is divided into two parts: Part One, Concepts and Strategies, discusses the linker groups used to attach the synthesis substrate to the solid support, colorimetric tests to identify the presence of functional groups, combinatorial synthesis, and diversity-oriented synthesis. Readers will discover how solid-phase synthesis is currently used to facilitate the discovery of new molecular functionality. The final chapter discusses how using a support can change or increase reaction selectivity. Part Two, Applications, presents examples of the solid-phase synthesis of various classes of organic molecules. Chapters explore general asymmetric synthesis on a support, strategies for heterocyclic synthesis, and synthesis of radioactive organic molecules, dyes, dendrimers, and oligosaccharides. Each chapter ends with a set of conclusions that underscore the key concepts and methods. References in each chapter enable readers to investigate any topic in greater depth. With its presentation of basic concepts as well as recent findings and applications, Solid-Phase Organic Synthesis is the ideal starting point for students and researchers in organic, medicinal, and combinatorial chemistry who want to take full advantage of current solid-phase synthesis techniques.
Sisson Adam Handbook of Biodegradable Polymers. Isolation, Synthesis, Characterization and Applications Sisson Adam Handbook of Biodegradable Polymers. Isolation, Synthesis, Characterization and Applications Новинка

Sisson Adam Handbook of Biodegradable Polymers. Isolation, Synthesis, Characterization and Applications

15871.04 руб.
A comprehensive overview of biodegradable polymers, covering everything from synthesis, characterization, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and biomaterial-based regenerative therapies. An introductory section deals with such fundamentals as basic chemical reactions during degradation, the complexity of biological environments and experimental methods for monitoring degradation processes. The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the field seeking a deeper insight.
Chattopadhyay Shital K. Heterocycles in Natural Product Synthesis Chattopadhyay Shital K. Heterocycles in Natural Product Synthesis Новинка

Chattopadhyay Shital K. Heterocycles in Natural Product Synthesis

16983.49 руб.
Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Akihiko Kondo Bioprocessing of Renewable Resources to Commodity Bioproducts Akihiko Kondo Bioprocessing of Renewable Resources to Commodity Bioproducts Новинка

Akihiko Kondo Bioprocessing of Renewable Resources to Commodity Bioproducts

10433.71 руб.
This book provides the vision of a successful biorefinery—the lignocelluloic biomass needs to be efficiently converted to its constituent monomers, comprising mainly of sugars such as glucose, xylose, mannose and arabinose. Accordingly, the first part of the book deals with aspects crucial for the pretreatment and hydrolysis of biomass to give sugars in high yield, as well as the general aspects of bioprocessing technologies which will enable the development of biorefineries through inputs of metabolic engineering, fermentation, downstream processing and formulation. The second part of the book gives the current status and future directions of the biological processes for production of ethanol (a biofuel as well as an important commodity raw material), solvents (butanol, isobutanol, butanediols, propanediols), organic acids (lactic acid, 3-hydroxy propionic acid, fumaric acid, succinic acid and adipic acid), and amino acid (glutamic acid). The commercial production of some of these commodity bioproducts in the near future will have a far reaching effect in realizing our goal of sustainable conversion of these renewable resources and realizing the concept of biorefinery. Suitable for researchers, practitioners, graduate students and consultants in biochemical/ bioprocess engineering, industrial microbiology, bioprocess technology, metabolic engineering, environmental science and energy, the book offers: Exemplifies the application of metabolic engineering approaches for development of microbial cell factories Provides a unique perspective to the industry about the scientific problems and their possible solutions in making a bioprocess work for commercial production of commodity bioproducts Discusses the processing of renewable resources, such as plant biomass, for mass production of commodity chemicals and liquid fuels to meet our ever- increasing demands Encourages sustainable green technologies for the utilization of renewable resources Offers timely solutions to help address the energy problem as non-renewable fossil oil will soon be unavailable
Jay Lehr H. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils. Causes, Assessment, Prediction, Prevention, and Remediation Jay Lehr H. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils. Causes, Assessment, Prediction, Prevention, and Remediation Новинка

Jay Lehr H. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils. Causes, Assessment, Prediction, Prevention, and Remediation

11153.51 руб.
Provides the tools needed to analyze and solve acid drainage problems Featuring contributions from leading experts in science and engineering, this book explores the complex biogeochemistry of acid mine drainage, rock drainage, and acid sulfate soils. It describes how to predict, prevent, and remediate the environmental impact of acid drainage and the oxidation of sulfides, offering the latest sampling and analytical methods. Moreover, readers will discover new approaches for recovering valuable resources from acid mine drainage, including bioleaching. Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils reviews the most current findings in the field, offering new insights into the underlying causes as well as new tools to minimize the harm of acid drainage: Part I: Causes of Acid Mine Drainage, Rock Drainage and Sulfate Soils focuses on the biogeochemistry of acid drainage in different environments. Part II: Assessment of Acid Mine Drainage, Rock Drainage and Sulfate Soils covers stream characterization, aquatic and biological sampling, evaluation of aquatic resources, and some unusual aspects of sulfide oxidation. Part III: Prediction and Prevention of Acid Drainage discusses acid-base accounting, kinetic testing, block modeling, petrology, and mineralogy studies. It also explains relevant policy and regulations. Part IV: Remediation of Acid Drainage, Rock Drainage and Sulfate Soils examines both passive and active cleanup methods to remediate acid drainage. Case studies from a variety of geologic settings highlight various approaches to analyzing and solving acid drainage problems. Replete with helpful appendices and an extensive list of web resources, Acid Mine Drainage, Rock Drainage, and Acid Sulfate Soils is recommended for mining engineers and scientists, regulatory officials, environmental scientists, land developers, and students.
Thomas Nugent C. Chiral Amine Synthesis. Methods, Developments and Applications Thomas Nugent C. Chiral Amine Synthesis. Methods, Developments and Applications Новинка

Thomas Nugent C. Chiral Amine Synthesis. Methods, Developments and Applications

18170.11 руб.
This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a «Who's Who» of the subject, providing a large array of highly practical information concentrated into the useful and essential methods. Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.
Vikas Mittal High Performance Polymers and Engineering Plastics Vikas Mittal High Performance Polymers and Engineering Plastics Новинка

Vikas Mittal High Performance Polymers and Engineering Plastics

14461.93 руб.
This book describes advances in synthesis, processing, and technology of environmentally friendly polymers generated from renewable resources. With contents based on a wide range of functional monomers and contributions from eminent researchers, this volume demonstrates the design, synthesis, properties and applications of plant oil based polymers, presenting an elaborate review of acid mediated polymerization techniques for the generation of green polymers. Chemical engineers are provided with state-of-the-art information that acts to further progress research in this direction.
Piet W. N. M. van Leeuwen Phosphorus(III) Ligands in Homogeneous Catalysis. Design and Synthesis Piet W. N. M. van Leeuwen Phosphorus(III) Ligands in Homogeneous Catalysis. Design and Synthesis Новинка

Piet W. N. M. van Leeuwen Phosphorus(III) Ligands in Homogeneous Catalysis. Design and Synthesis

14981.07 руб.
Over the last 60 years the increasing knowledge of transition metal chemistry has resulted in an enormous advance of homogeneous catalysis as an essential tool in both academic and industrial fields. Remarkably, phosphorus(III) donor ligands have played an important role in several of the acknowledged catalytic reactions. The positive effects of phosphine ligands in transition metal homogeneous catalysis have contributed largely to the evolution of the field into an indispensable tool in organic synthesis and the industrial production of chemicals. This book aims to address the design and synthesis of a comprehensive compilation of P(III) ligands for homogeneous catalysis. It not only focuses on the well-known traditional ligands that have been explored by catalysis researchers, but also includes promising ligand types that have traditionally been ignored mainly because of their challenging synthesis. Topics covered include ligand effects in homogeneous catalysis and rational catalyst design, P-stereogenic ligands, calixarenes, supramolecular approaches, solid phase synthesis, biological approaches, and solubility and separation. Ligand families covered in this book include phosphine, diphosphine, phosphite, diphosphite, phosphoramidite, phosphonite, phosphinite, phosphole, phosphinine, phosphinidenene, phosphaalkenes, phosphaalkynes, P-chiral ligands, and cage ligands. Each ligand class is accompanied by detailed and reliable synthetic procedures. Often the rate limiting step in the application of ligands in catalysis is the synthesis of the ligands themselves, which can often be very challenging and time consuming. This book will provide helpful advice as to the accessibility of ligands as well as their synthesis, thereby allowing researchers to make a more informed choice. Phosphorus(III) Ligands in Homogeneous Catalysis: Design and Synthesis is an essential overview of this important class of catalysts for academic and industrial researchers working in catalyst development, organometallic and synthetic chemistry.
Johnson Douglas S. Modern Drug Synthesis Johnson Douglas S. Modern Drug Synthesis Новинка

Johnson Douglas S. Modern Drug Synthesis

9863.77 руб.
Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of process synthesis versus the discovery synthetic route, Modern Drug Synthesis features authoritative coverage by distinguished editors and authors (some chapter authors are the actual inventor of the drug) of twenty different drug molecules.
Ravin Narain Engineered Carbohydrate-Based Materials for Biomedical Applications. Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels Ravin Narain Engineered Carbohydrate-Based Materials for Biomedical Applications. Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels Новинка

Ravin Narain Engineered Carbohydrate-Based Materials for Biomedical Applications. Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels

10382.92 руб.
This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.
Xiao-Feng Wu Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation Xiao-Feng Wu Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation Новинка

Xiao-Feng Wu Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation

11309.22 руб.
Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.
Laurie Starkey S. Introduction to Strategies for Organic Synthesis Laurie Starkey S. Introduction to Strategies for Organic Synthesis Новинка

Laurie Starkey S. Introduction to Strategies for Organic Synthesis

3852.81 руб.
The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
Stephen Pedneault Anatomy of a Fraud Investigation. From Detection to Prosecution Stephen Pedneault Anatomy of a Fraud Investigation. From Detection to Prosecution Новинка

Stephen Pedneault Anatomy of a Fraud Investigation. From Detection to Prosecution

3708.19 руб.
A one-of-a-kind resource walking you through one complete fraud investigation, from the original tip to conviction in court Anatomy of a Fraud Investigation is an engrossing read and a valuable resource for fraud investigators, auditors, or anyone who suspects fraud may be occuring in their organizations and is unsure as to how to act. It details all phases of a fraud investigation from the first suspicion of fraud to the final judgment in court, through the eyes of a forensic accountant. In each phase, the author provides insights based on his twenty-two years as a forensic accountant from where to sit at the table when you bring the suspected fraudster in for questioning, to how you protect the key sources of information that the suspect will try to destroy once he or she realizes they are under investigation. In-depth analysis of a fraud investigation Based on an actual investigation conducted by the author Each chapter contains valuable tips and key considerations, providing subtext for why decisions were made and bringing to light potential risks A fascinating, insider look at a fraud investigation, Anatomy of a Fraud Investigation helps you better understand fraud detection, investigation, and prevention-from the inside out.
René Peters Cooperative Catalysis. Designing Efficient Catalysts for Synthesis René Peters Cooperative Catalysis. Designing Efficient Catalysts for Synthesis Новинка

René Peters Cooperative Catalysis. Designing Efficient Catalysts for Synthesis

15259.94 руб.
Written by experts in the field, this is a much-needed overview of the rapidly emerging field of cooperative catalysis. The authors focus on the design and development of novel high-performance catalysts for applications in organic synthesis (particularly asymmetric synthesis), covering a broad range of topics, from the latest progress in Lewis acid / Br?nsted base catalysis to e.g. metal-assisted organo catalysis, cooperative metal/enzyme catalysis, and cooperative catalysis in polymerization reactions and on solid surfaces. The chapters are classified according to the type of cooperating activating groups, and describe in detail the different strategies of cooperative activation, highlighting their respective advantages and pitfalls. As a result, readers will learn about the different concepts of cooperative catalysis, their corresponding modes of operation and their applications, thus helping to find a solution to a specific synthetic catalysis problem.
Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology Новинка

Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology

14461.93 руб.
Presents the synthesis, technology and processing details of a large range of polymers derived from renewable resources It has been a long-term desire to replace polymers from fossil fuels with the more environmentally friendly polymers generated from renewable resources. Now, with the recent advancements in synthesis technologies and the finding of new functional monomers, research in this field has shown strong potential in generating better property polymers from renewable resources. A text describing these advances in synthesis, processing, and technology of such polymers not only provides the state-of-the-art information to researchers, but also acts to stimulate research in this direction. The contents are based on a wide range of functional monomers and the contributions are written by eminent researchers. Specifically Renewable Polymers: Demonstrates the design, synthesis, properties and applications of plant oil-based polymers Presents an elaborate review of acid mediated polymerization techniques for the generation of green polymers Details the production of polyhydroxyalkanoates (PHA) from olive oil based wastewater Describes the use of atom transfer radical polymerization (ATRP) techniques Reviews the renewable polymers derived from transgenic crop plants Provides an overview of a range of biomass-based polymers Concludes with the recent efforts and approaches exploiting the natural materials in developing drug delivery systems.
Kathy Lu Advances in Synthesis, Processing, and Applications of Nanostructures Kathy Lu Advances in Synthesis, Processing, and Applications of Nanostructures Новинка

Kathy Lu Advances in Synthesis, Processing, and Applications of Nanostructures

10005.52 руб.
With contributed papers from the 2011 Materials Science and Technology symposia, this is a useful one-stop resource for understanding the most important issues in advances in the synthesis, processing, and applications of nanostructures. Logically organized and carefully selected, the articles cover the themes of the symposia: Nanotechnology for Energy, Healthcare and Industry; Controlled Synthesis Processing and Applications of Structural and Functional Nanomaterials; and Synthesis, Properties, and Applications of Noble Metal Nanostructures. A must for academics in mechanical and chemical engineering, materials and or ceramics, and chemistry.
R. Sabnis W. Handbook of Biological Dyes and Stains. Synthesis and Industrial Applications R. Sabnis W. Handbook of Biological Dyes and Stains. Synthesis and Industrial Applications Новинка

R. Sabnis W. Handbook of Biological Dyes and Stains. Synthesis and Industrial Applications

13497.8 руб.
A complete, up-to-date resource of information on more than 200 dyes and stains Handbook of Biological Dyes and Stains is the most comprehensive volume available on the subject, covering all the available dyes and stains known to date in the literature for use in biology and medicine. Top dye expert Dr. Ram Sabnis organizes the compounds alphabetically by the most commonly used chemical name. He presents an easy-to-use reference complete with novel ideas for breakthrough research in medical, biological, chemical, and related fields. This is the first book to give the CAS registry number, chemical structure, Chemical Abstracts index name, all other chemical names, Merck Index number, chemical/dye class, molecular formula, molecular weight, physical form, solubility, melting point, boiling point, pH range, color change at pH, pKa, absorption, and emission maxima of dyes and stains, as well as to provide access to synthesis procedures (lab scale and industrial scale) of dyes and stains. This user-friendly handbook also features references on safety, toxicity, and adverse effects of dyes and stains on humans, animals, and the environment, including: acute/chronic toxicity aquatic toxicity carcinogenicity cytotoxicity ecotoxicity genotoxicity hepatotoxicity marine toxicity mutagenicity nephrotoxicity neurotoxicity oral toxicity phototoxicity phytotoxicity The use of biological dyes and stains has extremely high potential in today's business environment. This makes Handbook of Biological Dyes and Stains a convenient, must-have reference. Its staining, biological, and industrial applications make it a vital resource for industrial and academic researchers; the book also serves as a valuable desktop reference for medical professionals, biologists, chemists, chemical/optical engineers, physicists, materials scientists, intellectual property professionals, students, and professors.
Vijay Thakur Kumar Nanocellulose Polymer Nanocomposites. Fundamentals and Applications Vijay Thakur Kumar Nanocellulose Polymer Nanocomposites. Fundamentals and Applications Новинка

Vijay Thakur Kumar Nanocellulose Polymer Nanocomposites. Fundamentals and Applications

16340.32 руб.
Biorenewable polymers based nanomaterials are rapidly emerging as one of the most fascinating materials for multifunctional applications. Among biorenewable polymers, cellulose based nanomaterials are of great importance due to their inherent advantages such as environmental friendliness, biodegradability, biocompatibility, easy processing and cost effectiveness, to name a few. They may be produced from biological systems such as plants or be chemically synthesised from biological materials. This book summarizes the recent remarkable achievements witnessed in green technology of cellulose based nanomaterials in different fields ranging from biomedical to automotive. This book also discusses the extensive research developments for next generation nanocellulose-based polymer nanocomposites. The book contains seventeen chapters and each chapter addresses some specific issues related to nanocellulose and also demonstrates the real potentialities of these nanomaterials in different domains. The key features of the book are: Synthesis and chemistry of nanocellulose from different biorenewable resources Different characterization of nanocellulosic materials and their respective polymer nanocomposites Physico-chemical, thermal and mechanical investigation of nanocellulose based polymer nanocomposites Provides elementary information and rich understanding of the present state-of- art of nanocellulose-based materials Explores the full range of applications of different nanocellulose-based materials.
Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules Новинка

Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules

12233.31 руб.
All the latest tools needed to plan and perform the synthesis of complex bioactive molecules Focusing on organic, organometallic, and bio-oriented processes, this book explores the impact and use of the latest synthetic tools for the synthesis of complex biologically active compounds. Readers will discover step by step how these synthetic tools have provided new, elegant solutions to many synthetic puzzles. Moreover, they will discover innovative methods that make it possible to control the exact connectivity of atoms within a molecule in order to set precise three-dimensional arrangements. Modern Tools for the Synthesis of Complex Bioactive Molecules features sixteen chapters, each one written by one or more leading experts in organic synthesis from around the world. It covers a broad range of topics that enable readers to take advantage of the latest methods for synthesizing complex molecules, including: Modern catalysis, emphasizing key transformations such as C-H functionalizations, cross-couplings, gold-catalyzed reactions, metathesis-based syntheses, and asymmetric organocatalysis Eco-compatible transformations, including rearrangements and domino reactions Tools for the synthesis of carbohydrates and alkaloids New techniques, including the use of fluorous tags and engineered biosynthesis The last two chapters explore target- and diversity-oriented organic synthesis as well as the use of DNA-based asymmetric catalysis, which are all promising tools for the successful synthesis of complex bioactive molecules. Modern Tools for the Synthesis of Complex Bioactive Molecules is ideal for students and researchers who need to plan and perform the synthesis of complex molecules as efficiently as possible. The book's expert advice will help these readers quickly resolve a broad range of problems that can arise in organic syntheses.
Zhiyong Tang Chiral Nanomaterials. Preparation, Properties and Applications Zhiyong Tang Chiral Nanomaterials. Preparation, Properties and Applications Новинка

Zhiyong Tang Chiral Nanomaterials. Preparation, Properties and Applications

11517.51 руб.
Thorough and up-to-date, this book presents recent developments in this exciting research field. To begin with, the text covers the fabrication of chiral nanomaterials via various synthesis methods, including electron beam lithography, ion beam etching, chemical synthesis and biological DNA directed assembly. This is followed by the relevant theory and reaction mechanisms, with a discussion of the characterization of chiral nanomaterials according to the optical properties of metal nanoparticles, semiconductor nanocrystals, and nanoclusters. The whole is rounded off by a summary of applications in the field of catalysis, sensors, and biomedicine. With its comprehensive yet concise coverage of the whole spectrum of research, this is invaluable reading for senior researchers and entrants to the field of nanoscience and materials science.
Clemens Lamberth Bioactive Carboxylic Compound Classes. Pharmaceuticals and Agrochemicals Clemens Lamberth Bioactive Carboxylic Compound Classes. Pharmaceuticals and Agrochemicals Новинка

Clemens Lamberth Bioactive Carboxylic Compound Classes. Pharmaceuticals and Agrochemicals

15475.74 руб.
Following the successful and proven concept used in «Bioactive Heterocyclic Compound Classes» by the same editors, this book is the first to present approved pharmaceutical and agrochemical compounds classified by their carboxylic acid functionality in one handy volume. Each of the around 40 chapters describes one or two typical syntheses of a specific compound class and provides concise information on the history of development, mode of action, biological activity and field of application, as well as structure-activity relationships. In addition, similarities and differences between pharmaceuticals and agrochemicals are discussed in the introduction. Written by a team of experts in the field, this is a useful reference for researchers in academia and chemical or pharmaceutical companies working in the field of total synthesis and natural product chemistry, drug development, and crop protection research.
Bittner Michael L. Epistemology of the Cell. A Systems Perspective on Biological Knowledge Bittner Michael L. Epistemology of the Cell. A Systems Perspective on Biological Knowledge Новинка

Bittner Michael L. Epistemology of the Cell. A Systems Perspective on Biological Knowledge

9418.79 руб.
Honorable mention – Biomedicine and Neuroscience, 2011 Prose Awards An examination of how the cell should be described in order to effectively process biological data «The fruitful pursuit of biological knowledge requires one to take Einstein's admonition [on science without epistemology] as a practical demand for scientific research, to recognize Waddington's characterization of the subject matter of biology, and to embrace Wiener's conception of the form of biological knowledge in response to its subject matter. It is from this vantage point that we consider the epistemology of the cell.» —from the Preface In the era of high biological data throughput, biomedical engineers need a more systematic knowledge of the cell in order to perform more effective data handling. Epistemology of the Cell is the first authored book to break down this knowledge. This text examines the place of biological knowledge within the framework of science as a whole and addresses issues focused on the specific nature of biology, how biology is studied, and how biological knowledge is translated into applications, in particular with regard to medicine. The book opens with a general discussion of the historical development of human understanding of scientific knowledge, the scientific method, and the manner in which scientific knowledge is represented in mathematics. The narrative then gets specific for biology, focusing on knowledge of the cell, the basic unit of life. The salient point is the analogy between a systems-based analysis of factory regulation and the regulation of the cell. Each chapter represents a key topic of current interest, including: Causality and randomness Translational science Stochastic validation: classification Stochastic validation: networks Model-based experimentation in biology Epistemology of the Cell is written for biomedical researchers whose interests include bioinformatics, biological modeling, biostatistics, and biological signal processing.
Anslyn Eric V. Chemosensors. Principles, Strategies, and Applications Anslyn Eric V. Chemosensors. Principles, Strategies, and Applications Новинка

Anslyn Eric V. Chemosensors. Principles, Strategies, and Applications

12678.29 руб.
A thorough, accessible, and general overview of chemosensors Providing a comprehensive overview of chemosensors—organic molecules designed to bind and sense small molecules or metal ions—and their applications, Chemosensors: Principles, Strategies, and Applications is an accessible one-stop resource for analysts, clinicians, and graduate students studying advanced chemistry and chemosensing. Chemosensors function on a molecular level, generating a signal upon binding. The book reviews their synthesis, design, and applications for detecting biological and organic molecules as well as metal ions. The text highlights applications in drug discovery and catalyses that have not been well covered elsewhere. Covering such topics as molecular recognition, detection methods, design strategies, and important biological issues, the book is broken into four sections that examine intermolecular interactions, strategies in sensor design, detection methods, and case studies in metal, saccharide, and amino acid sensing. An indispensable source of information for chemical and biomedical experts using sensors, Chemosensors includes case studies to make the material both accessible and understandable to chemists of all backgrounds.
Loong-Tak Lim Poly(lactic acid). Synthesis, Structures, Properties, Processing, and Applications Loong-Tak Lim Poly(lactic acid). Synthesis, Structures, Properties, Processing, and Applications Новинка

Loong-Tak Lim Poly(lactic acid). Synthesis, Structures, Properties, Processing, and Applications

13100.53 руб.
This book describes the synthesis, properties, and processing methods of poly(lactic acid) (PLA), an important family of degradable plastics. As the need for environmentally-friendly packaging materials increases, consumers and companies are in search for new materials that are largely produced from renewable resources, and are recyclable. To that end, an overall theme of the book is the biodegradability, recycling, and sustainability benefits of PLA. The chapters, from a base of international expert contributors, describe specific processing methods, spectroscopy techniques for PLA analysis, and and applications in medical items, packaging, and environmental use.
Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Новинка

Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology

15836.32 руб.
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.
Dermot O'Hare Local Structural Characterisation. Inorganic Materials Series Dermot O'Hare Local Structural Characterisation. Inorganic Materials Series Новинка

Dermot O'Hare Local Structural Characterisation. Inorganic Materials Series

9573.23 руб.
Inorganic materials are at the heart of many contemporary real-world applications, in electronic devices, drug delivery, bio-inspired materials and energy storage and transport. In order to underpin novel synthesis strategies both to facilitate these applications and to encourage new ones, a thorough review of current and emerging techniques for materials characterisation is needed. Examining important techniques that allow investigation of the structures of inorganic materials on the local atomic scale, Local Structural Characterisation discusses: Solid-State NMR Spectroscopy X-Ray Absorption and Emission Spectroscopy Neutrons and Neutron Spectroscopy EPR Spectroscopy of Inorganic Materials Analysis of Functional Materials by X-Ray Photoelectron Spectroscopy This addition to the Inorganic Materials Series provides a detailed and thorough review of these spectroscopic techniques and emphasises the interplay between chemical synthesis and physical characterisation.
Janine Cossy Metathesis in Natural Product Synthesis. Strategies, Substrates and Catalysts Janine Cossy Metathesis in Natural Product Synthesis. Strategies, Substrates and Catalysts Новинка

Janine Cossy Metathesis in Natural Product Synthesis. Strategies, Substrates and Catalysts

15763.93 руб.
Emphasizing the impact of metathesis in natural product synthesis through the different types of key reactions, this is a comprehensive view of a hot topic. Written by top international authors, this ready reference is clearly structured and packed with important information, including representative experimental procedures for practical applications. A real must-have for anyone working in natural product synthesis.
Hongzhe Sun Biological Chemistry of Arsenic, Antimony and Bismuth Hongzhe Sun Biological Chemistry of Arsenic, Antimony and Bismuth Новинка

Hongzhe Sun Biological Chemistry of Arsenic, Antimony and Bismuth

14610.25 руб.
Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison – and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia – it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: chemistry of As, Sb and Bi biological chemistry of arsenic biological chemistry of Sb and Bi arsenic and antimony speciation in environmental and biological samples arsenic in traditional chinese medicine arsenic in aquifers biomethylation of As, Sb and Bi uptake of metalloids by cells bismuth complexes of porphyrins and their potential in medical applications Helicobacter pylori and bismuth metabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patients anticancer properties of As, Sb and Bi radio-Bi in cancer therapy genotoxicity of As, Sb and Bi metallomics as a new technique for As, Sb and Bi metalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.
Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications Новинка

Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications

12678.29 руб.
This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.
Srinivasan Chandrasekaran Click Reactions in Organic Synthesis Srinivasan Chandrasekaran Click Reactions in Organic Synthesis Новинка

Srinivasan Chandrasekaran Click Reactions in Organic Synthesis

13676.92 руб.
This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures. By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.
Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry Новинка

Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry

15871.04 руб.
An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Gordon Gribble W. Indole Ring Synthesis. From Natural Products to Drug Discovery Gordon Gribble W. Indole Ring Synthesis. From Natural Products to Drug Discovery Новинка

Gordon Gribble W. Indole Ring Synthesis. From Natural Products to Drug Discovery

15836.32 руб.
Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade – highlighted by the power of transition metal catalysis – this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds Новинка

Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds

14036.82 руб.
This book aims to overview the role of non-covalent interactions, such as hydrogen and halogen bonding, π-π, π-anion and electrostatic interactions, hydrophobic effects and van der Waals forces in the synthesis of organic and inorganic compounds, as well as in design of new crystals and function materials. The proposed book should allow to combine, in a systematic way, recent advances on the application of non-covalent interactions in synthesis and design of new compounds and functional materials with significance in Inorganic, Organic, Coordination, Organometallic, Pharmaceutical, Biological and Material Chemistries. Therefore, it should present a multi- and interdisciplinary character assuring a rather broad scope. We believe it will be of interest to a wide range of academic and research staff concerning the synthesis of new compounds, catalysis and materials. Each chapter will be written by authors who are well known experts in their respective fields.
Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Новинка

Ji Zhang Macrocyclic Polyamines. Synthesis and Applications

11877.41 руб.
The first comprehensive book focusing on synthesis and applications of macrocyclic polyamines and their derivatives Macrocyclic polyamines are a class of widely used important compounds. This is the first book that systematically summarizes the synthesis and applications of macrocyclic polyamines and their analogues, including the properties and synthetic methods of macrocyclic polyamines, chemical nucleases based on macrocyclic polyamines, the derivatives of macrocyclic polyamines as nano-vector materials, macrocyclic polyamines derivatives for bio-imaging, chemical sensors based on macrocyclic polyamines, and other applications of macrocyclic polyamines. Macrocyclic Polyamines: Synthesis and Applications includes most of the studies involving macrocyclic polyamines and their derivatives, and may be used as a reference for the researchers in related fields. It offers in-depth coverage of cyclization modes; special procedures for tetraza macrocyclic compounds; diacids-diamines condensation; oxidative DNA cleaving by macrocyclic polyamines; lipids with cationic MPA headgroups; the derivatives of DOTA, DO3A, and PCTA; receptors for anions; sensors for bioactive molecules; macrocyclic polyamines for solvent extraction and membrane transport of amino acids and their derivatives, electrophoretic separation, and open-tubular CEC; and much more. The first book that systematically summarizes the chemistry of macrocyclic polyamines and their derivatives in terms of synthetic methods for their preparation, functionalization, and application in the main fields of chemical sensors, chemical nucleases, drug-delivery, bio-imaging and vector materials Provides a comprehensive reference for the researchers working on macrocyclic polyamines Offers train of thought in related research fields such as organic chemistry, coordination chemistry, analytical chemistry, supramolecular chemistry, biomaterials, etc. Macrocyclic Polyamines: Synthesis and Applications will not only provide a reference for the researchers working on macrocyclic polyamines, but also offer opportunities for researchers in related research fields to understand the benefits of these key compounds.
V. Nenajdenko Isocyanide Chemistry. Applications in Synthesis and Material Science V. Nenajdenko Isocyanide Chemistry. Applications in Synthesis and Material Science Новинка

V. Nenajdenko Isocyanide Chemistry. Applications in Synthesis and Material Science

2072.88 руб.
The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in different branches of organic, inorganic, coordination, combinatorial and medicinal chemistry. This invaluable reference is the only book to cover the topic in such depth, presenting all aspects of synthetic isonitrile chemistry. The highly experienced and internationally renowned editor has brought together an equally distinguished team of authors who cover multicomponent reactions, isonitriles in total synthesis, isonitriles in polymer chemistry and much more.
Kanishka Biswas Essentials of Inorganic Materials Synthesis Kanishka Biswas Essentials of Inorganic Materials Synthesis Новинка

Kanishka Biswas Essentials of Inorganic Materials Synthesis

7194.6 руб.
This compact handbook describes all the important methods of synthesis employed today for synthesizing inorganic materials. Some features: Focuses on modern inorganic materials with applications in nanotechnology, energy materials, and sustainability Synthesis is a crucial component of materials science and technology; this book provides a simple introduction as well as an updated description of methods Written in a very simple style, providing references to the literature to get details of the methods of preparation when required
Daniel Simberloff Integrating Biological Control into Conservation Practice Daniel Simberloff Integrating Biological Control into Conservation Practice Новинка

Daniel Simberloff Integrating Biological Control into Conservation Practice

7867.28 руб.
Invasive species have a critical and growing effect upon natural areas. They can modify, degrade, or destroy wildland ecosystem structure and function, and reduce native biodiversity. Landscape-level solutions are needed to address these problems. Conservation biologists seek to limit such damage and restore ecosystems using a variety of approaches. One such approach is biological control: the deliberate importation and establishment of specialized natural enemies, which can address invasive species problems and which should be considered as a possible component of restoration. Biological control can be an effective tool against many invasive insects and plants but it has rarely been successfully employed against other groups. Safety is of paramount concern and requires that the natural enemies used be specialized and that targeted pests be drivers of ecological degradation. While modern approaches allow species to be selected with a high level of security, some risks do remain. However, as in all species introductions, these should be viewed in the context of the risk of failing to reduce the impact of the invasive species. This unique book identifies the balance among these factors to show how biological control can be integrated into ecosystem restoration as practiced by conservation biologists. Jointly developed by conservation biologists and biological control scientists, it contains chapters on matching tools to management goals; tools in action; measuring and evaluating ecological outcomes of biological control introductions; managing conflict over biological control; and includes case studies as well as an ethical framework for integrating biological control and conservation practice. Integrating Biological Control into Conservation Practice is suitable for graduate courses in invasive species management and biological control, as well as for research scientists in government and non-profit conservation organizations.

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Hyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process. Hyaluronic Acid: Production, Properties, Application in Biology and Medicine consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 describes the methods to manufacture and purify hyaluronic acid, including the analytical means for assessing quality of the finished product. Chapter 4 discusses the structure and rheological properties of hyaluronic acid considering effects on conformation and biological properties related to molecular weight. In Chapter 5, the physical and chemical methods for modifying the structure of hyaluronan are discussed including cross-linking using bi-functional reagents, solid-phase modification and effects of the combined action of high pressures and shift deformation. The final chapter focuses on the products derived from hyaluronic acid, including therapeutics composed of modified hyaluronan conjugated to vitamins, amino acids and oligo-peptides. The biological roles and medical applications of this polysaccharide have been extensively studied and this book provides a wealth of scientific data demonstrating the critical role of hyaluronic acid and its promise as a multifaceted bio-macromolecule. Approaching hyaluronic acid from multiple angles, this book links relationships between its biological functions, structure and physical–chemical properties. It will be an invaluable resource to researchers, both industrial and academic, involved in all aspects of hyaluronan-based technologies.
Продажа synthesis biological investigation of fluorinated amino acid analogs лучших цены всего мира
Посредством этого сайта магазина - каталога товаров мы очень легко осуществляем продажу synthesis biological investigation of fluorinated amino acid analogs у одного из интернет-магазинов проверенных фирм. Определитесь с вашими предпочтениями один интернет-магазин, с лучшей ценой продукта. Прочитав рекомендации по продаже synthesis biological investigation of fluorinated amino acid analogs легко охарактеризовать производителя как превосходную и доступную фирму.