the study of hypertensionantagonism of alpha 1d receptor



Michael Roberts F. Receptor Biology Michael Roberts F. Receptor Biology Новинка

Michael Roberts F. Receptor Biology

7123.89 руб.
This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on covering each receptor superfamily in detail including their structure and evolutionary context. The last part focusses exclusively on examples where thorough knowledge of receptors is critical: pharmaceutical research, developmental biology, neurobiology and evolutionary biology. Richly illustrated, the book is perfectly suited for all courses covering receptor based signaling, regardless whether they are part of the biology, medicine or pharmacology program.
Witlox Frank Commodity Chains and World Cities Witlox Frank Commodity Chains and World Cities Новинка

Witlox Frank Commodity Chains and World Cities

2718.8 руб.
Transnational spatial relations offer a key point from which to study the geographies of contemporary globalization. This book assesses the possible cross-fertilization between two of the most notable analytical frameworks – the world city network framework and the global commodity chain framework. Transnational spatial relations have become a key analytical lens through which to study the geographies of contemporary globalization Brings together contributions of key researchers from different backgrounds and different parts of the world Offers a set of original approaches to the study of the networked geography of globalization
Stevenson Robert Louis Dr Jekyll & Mr Hyde. The Merry Men & Other Stories Stevenson Robert Louis Dr Jekyll & Mr Hyde. The Merry Men & Other Stories Новинка

Stevenson Robert Louis Dr Jekyll & Mr Hyde. The Merry Men & Other Stories

366 руб.
In seeking to discover his inner self, the brilliant Dr Henry lekyll discovers a monster. First published to immediate acclaim in 1886, this mesmerising thriller is a terrifying study of the duality of man's nature, and it is the book which established Stevenson`s reputuation as a writer.Also included in this volume is Stevenson's 1887 collection of short stories, "The Merry Men and Other Tales and Fables"."The Merry Men" is a gripping Highland tale of shipwrecks and madness; "Markheim", the sinister study of the mind of a murderer; "Thrawn Janet", a spine-chilling tale of demonic possession; "Olalla", a study of degeneration and incipient vampirism in the Spanish mountains; "Will O' the Mill", a thought-provoking fable about a mountain inn-keeper; and "The Treasure of Franchard", a study of French bourgeois life.
А. А. Максуров Coordination in legal systems of the countries of Europe. Part I А. А. Максуров Coordination in legal systems of the countries of Europe. Part I Новинка

А. А. Максуров Coordination in legal systems of the countries of Europe. Part I

550 руб.
For the first time applied a coordination approach to the consideration of legal phenomena, thanks to which one can explore legal phenomenon from a new angle of view. The above mentioned gives opportunity in this case to improve the effectiveness of legal action. Usually the coordination rules of law are not the subject of a separate study. Such a study performed by the author on the example of the legislation of the countries of Europe, using a wide range of legal material. The research allowed to develop recommendations for improving the effectiveness of law due to the streamlining of coordination norms. Made of demarcation rules on the coordination and norms of cooperation, collaboration and other forms of interaction. Updated legal terminology. The proposed use of the coordination rules to certain legislative acts of the countries of Europe.
А. А. Максуров Coordination in legal systems of the countries of Europe. Part II А. А. Максуров Coordination in legal systems of the countries of Europe. Part II Новинка

А. А. Максуров Coordination in legal systems of the countries of Europe. Part II

550 руб.
For the first time applied a coordination approach to the consideration of legal phenomena, thanks to which one can explore legal phenomenon from a new angle of view. The above mentioned gives opportunity in this case to improve the effectiveness of legal action. Usually the coordination rules of law are not the subject of a separate study. Such a study performed by the author on the example of the legislation of the countries of Europe, using a wide range of legal material. The research allowed to develop recommendations for improving the effectiveness of law due to the streamlining of coordination norms. Made of demarcation rules on the coordination and norms of cooperation, collaboration and other forms of interaction. Updated legal terminology. The proposed use of the coordination rules to certain legislative acts of the countries of Europe.
Eric Csapo Actors and Icons of the Ancient Theater Eric Csapo Actors and Icons of the Ancient Theater Новинка

Eric Csapo Actors and Icons of the Ancient Theater

11586.98 руб.
Actors and Icons of the Ancient Theater examines actors and their popular reception from the origins of theater in Classical Greece to the Roman Empire Presents a highly original viewpoint into several new and contested fields of study Offers the first systematic survey of evidence for the spread of theater outside Athens and the impact of the expansion of theater upon actors and dramatic literature Addresses a study of the privatization of theater and reveals how it was driven by political interests Challenges preconceived notions about theater history
Robert Meyers A. Systems Biology Robert Meyers A. Systems Biology Новинка

Robert Meyers A. Systems Biology

29012.18 руб.
Systems biology is a relatively new biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. Systems biology is the study of the interconnected aspect of molecular, cellular, tissue, whole animal and ecological processes, and comprises mathematical and mechanistic studies of dynamical, mesoscopic, open, spatiotemporally defined, nonlinear, complex systems that are far from thermodynamic equilibrium.
Conan Doyle A. The Adventures of Sherlock Holmes Conan Doyle A. The Adventures of Sherlock Holmes Новинка

Conan Doyle A. The Adventures of Sherlock Holmes

244 руб.
This edition of "The Adventures of Sherlock Holmes" contains the earliest cases of the greatest fictional detective of all time. It comprises "A Study in Scarlet", "The Sign of Four" and the complete "Adventures of Sherlock Holmes", reprinted from...
Robin Murphy A. The Wiley Handbook on the Cognitive Neuroscience of Learning Robin Murphy A. The Wiley Handbook on the Cognitive Neuroscience of Learning Новинка

Robin Murphy A. The Wiley Handbook on the Cognitive Neuroscience of Learning

14623.43 руб.
The Wiley Handbook on the Cognitive Neuroscience of Learning charts the evolution of associative analysis and the neuroscientific study of behavior as parallel approaches to understanding how the brain learns that both challenge and inform each other. Covers a broad range of topics while maintaining an overarching integrative approach Includes contributions from leading authorities in the fields of cognitive neuroscience, associative learning, and behavioral psychology Extends beyond the psychological study of learning to incorporate coverage of the latest developments in neuroscientific research
Raymond Hickey A Dictionary of Varieties of English Raymond Hickey A Dictionary of Varieties of English Новинка

Raymond Hickey A Dictionary of Varieties of English

9970.46 руб.
A Dictionary of Varieties of English presents a comprehensive listing of the distinctive dialects and forms of English spoken throughout the contemporary world. Provides an invaluable introduction and guide to current research trends in the field Includes definitions both for the varieties of English and regions they feature, and for terms and concepts derived from a linguistic analysis of these varieties Explores important research issues including the transportation of dialects of English, the rise of ‘New Englishes’, sociolinguistic investigations of various English-speaking locales, and the study of language contact and change. Reflects our increased awareness of global forms of English, and the advances made in the study of varieties of the language in recent decades Creates an invaluable, informative resource for students and scholars alike, spanning the rich and diverse linguistic varieties of the most widely accepted language of international communication
Michael Church The Regulation of Peace River. A Case Study for River Management Michael Church The Regulation of Peace River. A Case Study for River Management Новинка

Michael Church The Regulation of Peace River. A Case Study for River Management

11619.63 руб.
This book presents a comprehensive overview of the first longitudinal study of the downstream response of a major river to the establishment of a large hydropower facility and dams. Peace River, a northward flowing boreal river in northwestern Canada was dammed in 1967 and the book describes the morphological response of the 1200 km downstream channel and the response of riparian vegetation to the change in flow regime over the first forty years of regulated flows. Beginning with a description of the effect of regulation on the flow and sediment regimes of the river, the book proceeds to study changes in downstream channel geometry on the main stem, on the lowermost course of tributaries, and on the hydraulic geometry, the overall morphology of the channel, and riparian vegetation succession. The river is subject to annual freeze-up and break-up, so a chapter is devoted to the ice regime of the river. A chapter compares the effects of two extraordinary post-regulation flood events. The penultimate chapter presents a prediction of the ultimate equilibrium form of the regulated river based on rational regime theory. An online database of all the main observations will provide invaluable material for advanced students of river hydraulics and geomorphology. This book carefully brings together a range of studies that have been previously inaccessible providing a rare and comprehensive analysis of the effects of a big dam on a river, a river that itself represents an example of the kind of system that is likely to receive considerable attention in the future from dam engineers and environmentalists. • An invaluable reference to river scientists, hydroelectric power developers, engineers and environmentalists • Focus on a northward flowing boreal river, a type that holds most of the remaining hydroelectric power potential in the Northern Hemisphere • Exceptional separation of water and sediment sources, permitting study of the isolated effect of manipulating one of the two major governing conditions of river processes and form • Unique example of water regulation and both natural and engineered flood flows • Detailed study of both morphological changes of the channel and of the riparian vegetation • Online data supplement including major data tables and numerous maps. Details of the main observations and provides material for problem study by advanced students of river hydraulics and geomorphology are provided
Conan Doyle A. A Study in Scarlet & The Sigh of the Four Conan Doyle A. A Study in Scarlet & The Sigh of the Four Новинка

Conan Doyle A. A Study in Scarlet & The Sigh of the Four

231 руб.
"Doctor Watson, Mr Sherlock Holmes" - The most famous introduction in the history of crime fiction takes place in Arthur Conan Doyle's "A Study in Scarlet", bringing together Sherlock Holmes, the master of cience detection, and John H. Watson, the great ... .
Decommunized: Ukranian Soviet Mosaics Decommunized: Ukranian Soviet Mosaics Новинка

Decommunized: Ukranian Soviet Mosaics

3680 руб.
The book presents the first comprehensive study of Soviet monumental mosaics, outstanding artifacts of the cultural heritage of the era. Photographer Yevgen Nikiforov spent...
Janet Carsten Blood Will Out. Essays on Liquid Transfers and Flows Janet Carsten Blood Will Out. Essays on Liquid Transfers and Flows Новинка

Janet Carsten Blood Will Out. Essays on Liquid Transfers and Flows

2621.03 руб.
Unique in focus and international in scope, this book brings together 10 essays about the material, metaphorical, and symbolic importance of blood. An interdisciplinary study that unites the work of noted historians and anthropologists Incorporates insights from recent work in symbolism, kinship studies, medical anthropology, the anthropology of religion, the sociological study of finance, and textual analysis Covers topics such as Medieval European conceptions of blood; blood and the brain; blood and the cultural study of finance; and blood types, identity, and association in twentieth-century America
ALEX ESIPOB ALPHA… OMEGA. COLORING BOOK ALEX ESIPOB ALPHA… OMEGA. COLORING BOOK Новинка

ALEX ESIPOB ALPHA… OMEGA. COLORING BOOK

100 руб.
The international edition “ALPHA and OMEGA” is studying of English for children and adults. Assimilation happens in playful and creative way of a coloring, stories, copy-books and narrations for creative development with the best teacher. A copy-book, a coloring, drawing and also creativity, imagination with development of intelligence and active studying – fun and a competition for all family. Reduces stress at adults at study of children. Actively helps to learn, to draw and acquire English.
Roy Ananya Worlding Cities. Asian Experiments and the Art of Being Global Roy Ananya Worlding Cities. Asian Experiments and the Art of Being Global Новинка

Roy Ananya Worlding Cities. Asian Experiments and the Art of Being Global

7230.68 руб.
Worlding Cities is the first serious examination of Asian urbanism to highlight the connections between different Asian models and practices of urbanization. It includes important contributions from a respected group of scholars across a range of generations, disciplines, and sites of study. Describes the new theoretical framework of ‘worlding’ Substantially expands and updates the themes of capital and culture Includes a unique collection of authors across generations, disciplines, and sites of study Demonstrates how references to Asian power, success, and hegemony make possible urban development and limit urban politics
Michel Soustelle Modeling of Liquid Phases Michel Soustelle Modeling of Liquid Phases Новинка

Michel Soustelle Modeling of Liquid Phases

10654.88 руб.
This book is part of a set of books which offers advanced students successive characterization tool phases, the study of all types of phase (liquid, gas and solid, pure or multi-component), process engineering, chemical and electrochemical equilibria, and the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention has been given to the rigor of mathematical developments. This second volume in the set is devoted to the study of liquid phases.
Beverly Chin How to Study for Success Beverly Chin How to Study for Success Новинка

Beverly Chin How to Study for Success

1162.98 руб.
Develop powerful study skills that will last a lifetime! When you have strong study habits, you learn more in class, get more out of your homework, and, best of all, have a much easier time completing any type of assignment. How to Study for Success lets you build those habits and master essential study skills that will help you become a better student. Filled with easy-to-follow advice, this hands-on guide includes 7 Keys to Success that will help you improve your school performance: * Get Ready to Study Now * Get Organized * Make the Most of Class Time * Make the Most of Home Study Time * Make the Most of Homework * Put Your Computer to Good Use * Go the Extra Mile So get ready to improve your school performance-and study for success!
Raimo Pohjanvirta The AH Receptor in Biology and Toxicology Raimo Pohjanvirta The AH Receptor in Biology and Toxicology Новинка

Raimo Pohjanvirta The AH Receptor in Biology and Toxicology

13298.39 руб.
This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.
William Brock J. The Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides William Brock J. The Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides Новинка

William Brock J. The Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides

9673.78 руб.
A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives. The book: Provides a complete overview of nonclinical study organization, conduct, and reporting and describes the roles and responsibilities of a Study Director to manage an effective study Covers regulatory and scientific concepts, including international testing and Good Laboratory Practice (GLP), compliance with guidelines, and animal models Features a concluding chapter that compiles case studies / lessons learned from those that have served as a Study Director for many years Addresses the entire spectrum of nonclinical testing, making it applicable to those in the government, laboratories and those actively involved in in all sectors of industry
Salah Khalfallah Structural Analysis 1. Statically Determinate Structures Salah Khalfallah Structural Analysis 1. Statically Determinate Structures Новинка

Salah Khalfallah Structural Analysis 1. Statically Determinate Structures

10696.27 руб.
Using a general approach, this book supports the student to enable mastery of the methods of analysis of isostatic and hyperstatic structures. To show the performance of the methods of analysis of the hyperstatic structures, selected beams, gantries and reticular structures are selected and subjected to a comparative study by the different methods of analysis of the hyperstatic structures.
Murphy Raymond Essential Grammar in Use. A Self-Study Reference and Practice Book for Elementary Learners Murphy Raymond Essential Grammar in Use. A Self-Study Reference and Practice Book for Elementary Learners Новинка

Murphy Raymond Essential Grammar in Use. A Self-Study Reference and Practice Book for Elementary Learners

2006 руб.
The world's best-selling grammar series for learners of English. Essential Grammar in Use is a self-study reference and practice book for elementary-level learners (A1-B1), used by millions of people around the world. With clear examples, easy-to-follow exercises and answer key, the Fourth edition is perfect for independent study, covering all the areas of grammar that you will need at this level. The book has an easy-to-use format of two-page units with clear explanations of grammar points on the left-hand page, and practice exercises on the right. It also includes plenty of additional exercises and a Study Guide to help you find the grammar units you need to study. Fourth edition.
Ю. В. Першина Уроки Холокоста – путь к толерантности. The lessons of the Holocaust – the way to tolerance Ю. В. Першина Уроки Холокоста – путь к толерантности. The lessons of the Holocaust – the way to tolerance Новинка

Ю. В. Першина Уроки Холокоста – путь к толерантности. The lessons of the Holocaust – the way to tolerance

550 руб.
В пособии рассмотрена организация системно-деятельностного подхода при изучении темы Холокоста в российских образовательных организациях в условиях реализации ФГОС. Цель пособия – анализ роли практических занятий при изучении темы Холокоста на уроках истории и обществознания, во внеурочной деятельности, в воспитательной работе школы и системе повышения квалификации учителей. На основе анализа источников, отечественной и зарубежной литературы автором систематизирован материал по изучению темы Холокоста с использованием историко-системного метода. Пособие предназначено для студентов, обучающихся по специальностям «Отечественная история» и «Всеобщая история», а также для учителей истории, обществознания, классных руководителей и специалистов-историков. The manual considers the organization of the system-activity approach in the study of the Holocaust in Russian educational organizations in the context of the FGOS. The purpose of the manual – analysis of the role of practical training in the study of the Holocaust in the lessons of history and social studies, in extracurricular activities, educational work of the school and in the system of training of teachers. Based on the analysis of sources, domestic and foreign literature, the author systematized the material on the study of the Holocaust. The author used the historical-system method. The manual is intended for use in the educational process by students, masters, specialists studying in the field of «National history» and «Universal history», as well as for teachers of history, social science, class teachers.
Smain Femmam Fundamentals of Signals and Control Systems Smain Femmam Fundamentals of Signals and Control Systems Новинка

Smain Femmam Fundamentals of Signals and Control Systems

11998.84 руб.
The aim of this book is the study of signals and deterministic systems, linear, time-invariant, finite dimensions and causal. A set of useful tools is selected for the automatic and signal processing and methods of representation of dynamic linear systems are exposed, and analysis of their behavior. Finally we discuss the estimation, identification and synthesis of control laws for the purpose of stabilization and regulation. The study of signal characteristics and properties systems and knowledge of mathematical tools and treatment methods and analysis, are lately more and more importance and continue to evolve. The reason is that the current state of technology, particularly electronics and computing, enables the production of very advanced processing systems, effective and less expensive despite the complexity.
Alan Dorsey H. Active Alpha. A Portfolio Approach to Selecting and Managing Alternative Investments Alan Dorsey H. Active Alpha. A Portfolio Approach to Selecting and Managing Alternative Investments Новинка

Alan Dorsey H. Active Alpha. A Portfolio Approach to Selecting and Managing Alternative Investments

7390.15 руб.
Praise for Active Alpha «Active alpha is the quest for every sophisticated investor. This book covers all of the key alpha sources currently mined by active managers, reduces the complexity of the subject, and helps the investor get started in the right direction.» -Mark Anson, Chief Executive Officer, Hermes Pensions Management Ltd. «Long-held traditional methods for investing large portfolios are giving way to new processes that are designed to improve productivity and diversification. These changes find their locus in the sometimes overly mysterious world of absolute return strategies. In this book, Alan Dorsey demystifies that new world and provides a guiding pathway into the future of professional portfolio management. This is an important read for any investor who plans to succeed going forward.» -Britt Harris, Chief Investment Officer, Teacher Retirement System of Texas «With great lucidity, Alan Dorsey's book, Active Alpha, fills an important void by identifying the relevant institutional features of this complex subject and by providing a unifying analytic framework for understanding and constructing portfolios of alternative assets. For anyone investing in the alternative class, from the new student to the experienced practitioner, Active Alpha is a necessary read. I am recommending it to everyone I know with such an interest, and it is destined to become a much thumbed reference on my shelf.» -Steve Ross, Franco Modigliani Professor of Financial Economics, Sloan School, MIT
Erika Hoff Research Methods in Child Language. A Practical Guide Erika Hoff Research Methods in Child Language. A Practical Guide Новинка

Erika Hoff Research Methods in Child Language. A Practical Guide

2174.26 руб.
This is a comprehensive and accessible guide to the methods researchers use to study child language, written by experienced scholars in the study of language development. Presents a comprehensive survey of laboratory and naturalistic techniques used in the study of different domains of language, age ranges, and populations, and explains the questions addressed by each technique Presents new research methods, such as the use of functional Near Infrared Spectroscopy (fNIRS) to study the activity of the brain Expands on more traditional research methods such as collection, transcription, and coding of speech samples that have been transformed by new hardware and software
Gerard Ligozat Qualitative Spatial and Temporal Reasoning Gerard Ligozat Qualitative Spatial and Temporal Reasoning Новинка

Gerard Ligozat Qualitative Spatial and Temporal Reasoning

17036.25 руб.
Starting with an updated description of Allen's calculus, the book proceeds with a description of the main qualitative calculi which have been developed over the last two decades. It describes the connection of complexity issues to geometric properties. Models of the formalisms are described using the algebraic notion of weak representations of the associated algebras. The book also includes a presentation of fuzzy extensions of qualitative calculi, and a description of the study of complexity in terms of clones of operations.
Mehmet Asutay Takaful Investment Portfolios. A Study of the Composition of Takaful Funds in the GCC and Malaysia Mehmet Asutay Takaful Investment Portfolios. A Study of the Composition of Takaful Funds in the GCC and Malaysia Новинка

Mehmet Asutay Takaful Investment Portfolios. A Study of the Composition of Takaful Funds in the GCC and Malaysia

7390.15 руб.
A groundbreaking study of the investment portfolios of takaful companies, their general investment patterns, and their future investments The Islamic finance industry has witnessed remarkable growth over the last decade, and one of the most successful segments—poised for even greater expansion—is the Islamic insurance (takaful) industry. In Takaful Investment Portfolios, distinguished takaful scholar Abdulrahman Khalil Tolefat explores the investment portfolios of takaful companies in both the GCC countries and Malaysia, the tip of Islamic finance industry. Investigating the trends and patterns of investment of takaful companies, the book looks at shareholders as well as general and family funds to determine where these companies are investing today, and where they are likely to invest in the future. Presenting new and novel research on the investment patterns of takaful companies, Takaful Investment Portfolios covers the history of the industry and takaful models and how they work, and presents in-depth studies of both their real-world and desired portfolio investments. Presents unique new research into the investment portfolios of takaful companies in the GCC and Malaysia Examines the gap between desired and actual investment portfolios of takaful companies Explores expected areas for future investment Groundbreaking in its depth, Takaful Investment Portfolios is an unprecedented study of the investments of takaful companies.
Michael Ryan Literary Theory. A Practical Introduction Michael Ryan Literary Theory. A Practical Introduction Новинка

Michael Ryan Literary Theory. A Practical Introduction

7171.56 руб.
Literary Theory: A Practical Introduction, Third Edition, presents a comprehensive introduction to the full range of contemporary approaches to the study of literature and culture, from formalism, structuralism, and historicism to ethnic, gender, and science studies. Introduces students to a variety of contemporary approaches to the study of literature and culture Demonstrates how the varying perspectives on texts can lead to different interpretations of the same work Features numerous updates that include new literary texts, new and expanded sections Represents the ideal accompaniment to the upcoming Third Edition of Literary Theory: An Anthology
Per Runeson Case Study Research in Software Engineering. Guidelines and Examples Per Runeson Case Study Research in Software Engineering. Guidelines and Examples Новинка

Per Runeson Case Study Research in Software Engineering. Guidelines and Examples

5920.8 руб.
Based on their own experiences of in-depth case studies of software projects in international corporations, in this book the authors present detailed practical guidelines on the preparation, conduct, design and reporting of case studies of software engineering. This is the first software engineering specific book on the case study research method.
Gomtsyan Arthur Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders Gomtsyan Arthur Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders Новинка

Gomtsyan Arthur Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders

12446.57 руб.
Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis, chronic low back pain, neuropathic pain, and cancer pain, some consider it «the holy grail» of pain management. This dedicated reference summarizes available data related to the potential therapeutic utility for TRPV1 ligands. With contributions from many of the world's leading experts on TRP channels, Vanilloid Receptor TRPV1 in Drug Discovery covers the important TRPV1 target for drugs to treat painful conditions such as inflammation, arthritis, and cancer pain. The book discusses: Recent advances in biology, chemistry, and pharmacology at both the preclinical and clinical stage of the dynamic area of TRPV1 drug discovery research The potential for drugs targeting TRPV1 in painful conditions such as inflammation, arthritis, and cancer The development of analgesic drugs Other applications for TRPV1, including the treatment of respiratory disease and diabetes Featuring data relevant to the therapeutic potential of TRPV1 and the medicinal chemistry involved in designing TRPV1 antagonists, Vanilloid Receptor TRPV1 in Drug Discovery is a key tool for researchers in the pharmaceutical industry and academia involved in pain, ion channels, and analgesic drug development.
Shabbir Simjee Molecular Techniques for the Study of Hospital Acquired Infection Shabbir Simjee Molecular Techniques for the Study of Hospital Acquired Infection Новинка

Shabbir Simjee Molecular Techniques for the Study of Hospital Acquired Infection

12369.51 руб.
Providing a broad overview of the microbial pathogens associated with hospital-acquired human illness, Techniques for the Study of Hospital Acquired Infection examines the cost-effective use of laboratory techniques in nosocomial infectious disease epidemiology and control. This concise guide addresses the cost benefits of combining modern molecular techniques with the traditional activities of infection control departments. The book is useful as a guide to hospital infection control programs as well as a text for medical practitioners, grad/medical students, researcher scientists, population biologists, molecular biologists, and microbiologists.
Michel Soustelle Ionic and Electrochemical Equilibria Michel Soustelle Ionic and Electrochemical Equilibria Новинка

Michel Soustelle Ionic and Electrochemical Equilibria

10498.36 руб.
This book is part of a set of books which offers advanced students successive characterization tool phases, the study of all types of phase (liquid, gas and solid, pure or multi-component), process engineering, chemical and electrochemical equilibria, and the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention has been paid to the rigor of mathematical developments. This sixth volume is made up of two parts. The first part focuses on the study of ionic equilibria in water or non-aqueous solvents. The following are then discussed in succession: the dissociation of electrolytes, solvents and solvation, acid-base equilibria, formation of complexes, redox equilibria and the problems of precipitation. Part 2 discusses electrochemical thermodynamics, with the study of two groups: electrodes and electrochemical cells. The book concludes with the study of potential-pH diagrams and their generalization in an aqueous or non-aqueous medium.
Murphy, Raymond Essential Gram in Use 4Ed + ans Murphy, Raymond Essential Gram in Use 4Ed + ans Новинка

Murphy, Raymond Essential Gram in Use 4Ed + ans

1990 руб.
The world's best-selling grammar series for learners of English. Essential Grammar in Use is a self-study reference and practice book for elementary-level learners (A1-B1), used by millions of people around the world. With clear examples, easy-to-follow exercises and answer key, the Fourth edition is perfect for independent study, covering all the areas of grammar that you will need at this level. The book has an easy-to-use format of two-page units with clear explanations of grammar points on the left-hand page, and practice exercises on the right. It also includes plenty of additional exercises and a Study Guide to help you find the grammar units you need to study.
Doyle Arthur Conan A Study in Scarlet Doyle Arthur Conan A Study in Scarlet Новинка

Doyle Arthur Conan A Study in Scarlet

510 руб.
A Study in Scarlet (first published in 1987) marks the first appearance of Sherlock Holmes and Dr. Watson, who would become two of the most famous characters in popular fiction. Although Conan Doyle wrote 56 short stories featuring Holmes, A Study in Scarlet is one of only four full-length novels in the original canon.
Hugh McKenna The Delphi Technique in Nursing and Health Research Hugh McKenna The Delphi Technique in Nursing and Health Research Новинка

Hugh McKenna The Delphi Technique in Nursing and Health Research

4048.23 руб.
The Delphi Technique in Nursing and Health Research is a practical guide to using the Delphi methodology for students and researchers in nursing and health. It adopts a logical step-by-step approach, introducing the researcher to the Delphi, outlining its development, analysing key characteristics and parameters for its successful use and exploring its applications in nursing and health. The book addresses issues of methodology, design, framing the research question, sampling, instrumentation, methodological rigour, reliability and validity, and methods of data analysis. The Delphi Technique in Nursing and Health Research enables the reader to be aware of the limitations of the technique and possible solutions, to design a Delphi questionnaire for each of the different rounds of a study, to consider different approaches to the technique in relation to a study, to analyse the data from each round of a Delphi study, and to understand the importance of feedback between rounds. Key Features A practical guide to facilitate use of the Delphi technique Provides the reader with the necessary information to participate in and conduct Delphi studies Examines different types of Delphi, including the e-Delphi, and modifications made to the technique Includes examples of real empirical investigations, brief case scenarios and key learning points for each chapter Explores the role of the Delphi researcher Explores ethical issues and issues of anonymity, use of experts and controlled feedback
Michel Soustelle Phase Transformations Michel Soustelle Phase Transformations Новинка

Michel Soustelle Phase Transformations

7123.89 руб.
This book is part of a set of books which offers advanced students successive characterization tool phases, the study of all types of phase (liquid, gas and solid, pure or multi-component), process engineering, chemical and electrochemical equilibria, and the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention has been given to the rigor of mathematical developments. This fifth volume is devoted to the study of transformations and equilibria between phases. First- and second-order pure phase transformations are presented in detail, just as with the macroscopic and microscopic approaches of phase equilibria. In the presentation of binary systems, the thermodynamics of azeotropy and demixing are discussed in detail and applied to strictly-regular solutions. Eutectic and peritectic points are examined, as well as the reactions that go with them. The study of ternary systems then introduces the concepts of ternary azeotropes and eutectics. For each type of solid-liquid system, the interventions of definite compounds with or without congruent melting are taken into account. The particular properties of the different notable points of a diagram are also demonstrated.
Joyce Flueckiger Burkhalter Everyday Hinduism Joyce Flueckiger Burkhalter Everyday Hinduism Новинка

Joyce Flueckiger Burkhalter Everyday Hinduism

7495.27 руб.
This innovative introductory textbook explores the central practices and beliefs of Hinduism through contemporary, everyday practice. Introduces and contextualizes the rituals, festivals and everyday lived experiences of Hinduism in text and images Includes data from the author’s own extensive ethnographic fieldwork in central India (Chhattisgarh), the Deccan Plateau (Hyderabad), and South India (Tirupati) Features coverage of Hindu diasporas, including a study of the Hindu community in Atlanta, Georgia Each chapter includes case study examples of specific topics related to the practice of Hinduism framed by introductory and contextual material
Doyle, Arthur Conan A Study in Scarlet Doyle, Arthur Conan A Study in Scarlet Новинка

Doyle, Arthur Conan A Study in Scarlet

278 руб.
A Study in Scarlet (first published in 1987) marks the first appearance of Sherlock Holmes and Dr. Watson, who would become two of the most famous characters in popular fiction. Although Conan Doyle wrote 56 short stories featuring Holmes, A Study in Scarlet is one of only four full-length novels in the original canon.
David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts Новинка

David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts

2174.26 руб.
Moral Struggle and Religious Ethics offers a comparative discussion of the challenges of living a moral religious life. This is illustrated with a study of two key thinkers, Bonaventure and Buddhaghosa, who influenced the development of moral thinking in Christianity and Buddhism respectively. Provides an important and original contribution to the comparative study and practice of religious ethics Moves away from a comparison of theories by discussing the shared human problem of moral weakness Offers an fresh approach with a comparison of the understanding of the problem of moral weakness between the two key thinkers, Bonaventure and Buddhaghosa Written by a highly respected academic in the dynamic and fast-growing field of comparative religious ethics
David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts Новинка

David Clairmont A. Moral Struggle and Religious Ethics. On the Person as Classic in Comparative Theological Contexts

9520.1 руб.
Moral Struggle and Religious Ethics offers a comparative discussion of the challenges of living a moral religious life. This is illustrated with a study of two key thinkers, Bonaventure and Buddhaghosa, who influenced the development of moral thinking in Christianity and Buddhism respectively. Provides an important and original contribution to the comparative study and practice of religious ethics Moves away from a comparison of theories by discussing the shared human problem of moral weakness Offers an fresh approach with a comparison of the understanding of the problem of moral weakness between the two key thinkers, Bonaventure and Buddhaghosa Written by a highly respected academic in the dynamic and fast-growing field of comparative religious ethics
Michel Soustelle Thermodynamics of Surfaces and Capillary Systems Michel Soustelle Thermodynamics of Surfaces and Capillary Systems Новинка

Michel Soustelle Thermodynamics of Surfaces and Capillary Systems

8248.71 руб.
This book is part of a set of books which offers advanced students successive characterization tool phases, the study of all types of phase (liquid, gas and solid, pure or multi-component), process engineering, chemical and electrochemical equilibria, and the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention has been given to the rigor of mathematical developments. This volume, the final of the Chemical Thermodynamics Set, offers an in-depth examination of chemical thermodynamics. The author uses systems of liquids, vapors, solids and mixtures of these in thermodynamic approaches to determine the influence of the temperature and pressure on the surface tension and its consequences on specific heat capacities and latent heats. Electro-capillary phenomena, the thermodynamics of cylindrical capillary and small volume-phases are also discussed, along with a thermodynamic study of the phenomenon of nucleation of a condensed phase and the properties of thin liquid films. The final chapters discuss the phenomena of physical adsorption and chemical adsorption of gases by solid surfaces. In an Appendix, applications of physical adsorption for the determination of the specific areas of solids and their porosity are given.
Jiayi Liu Study on the Auditing System of Socialism with Chinese Characteristics Jiayi Liu Study on the Auditing System of Socialism with Chinese Characteristics Новинка

Jiayi Liu Study on the Auditing System of Socialism with Chinese Characteristics

5510.2 руб.
A comprehensive, authoritative examination of Chinese auditing practices Study on the Auditing System of Socialism with Chinese Characteristics provides unprecedented insight into China's current audit process, with expert contributions and predictions of future trends. Author Jiayi Liu is the Auditor General of the National Audit Office of the People's Republic of China, and the current chairman of the governing boards of the International Organizations of Supreme Audit Institutions; in this book, he draws upon his vast experience to help you better understand China's unique approach to auditing. Contributions from senior auditors across the China National Audit Office share deep insight into the system's framework, features, and development, providing a comprehensive, systematic examination of current, past, and future practices. As a leading global auditing authority, Liu is the ideal source of information and clarity on China's auditing system. This book opens up the practices, processes, and foundational aspects of this complex system to provide insight for those doing business in China. Understand the foundation of the Chinese auditing system Learn how the system was created and developed over time Delve into the system's framework and detailed features Gain first-hand insight into China's auditing experience Developed as a companion to Study on the Auditing Theory of Socialism with Chinese Characteristics, this book expands upon the system's basic foundations to show how theory translates into practice. Companies who do business in China need a working knowledge of the system, and a scientific examination from the definitive authority provides a level of insight you won't find anywhere else. Study on the Auditing System of Socialism with Chinese Characteristics is the essential primer to the Chinese audit.
Отсутствует The art of poetry. Vol. 2 Отсутствует The art of poetry. Vol. 2 Новинка

Отсутствует The art of poetry. Vol. 2

0 руб.
Полный вариант заголовка: «The art of poetry : Vol. 2 : on a new plan : illustrated with a great variety of examples from the best English poets : and of translations from the ancients : together with such reflections and critical remarks as may tend to form in our youth an elegant tаste, and render the study of this part of the belles lettres more rational and pleasing».
Charlie Rose Race and Social Change. A Quest, A Study, A Call to Action Charlie Rose Race and Social Change. A Quest, A Study, A Call to Action Новинка

Charlie Rose Race and Social Change. A Quest, A Study, A Call to Action

2470.91 руб.
A powerful study illuminates our nation's collective civic fault lines Recent events have turned the spotlight on the issue of race in modern America, and the current cultural climate calls out for more research, education, dialogue, and understanding. Race and Social Change: A Quest, A Study, A Call to Action focuses on a provocative social science experiment with the potential to address these needs. Through an analysis grounded in the perspectives of developmental psychology, adaptive leadership and complex systems theory, the inquiry at the heart of this book illuminates dynamics of race and social change in surprising and important ways. Author Max Klau explains how his own quest for insight into these matters led to the empirical study at the heart of this book, and he presents the results of years of research that integrate findings at the individual, group, and whole system levels of analysis. It's an effort to explore one of the most controversial and deeply divisive subject's in American civic life using the tools of social science and empiricism. Readers will: Review a long tradition of classic, provocative social science experiments and learn how the study presented here extends that tradition into new and unexplored territory Engage with findings from years of research that reveal insights into dynamics of race and social change unfolding simultaneously at the individual, group, and whole systems levels Encounter a call to action with implications for our own personal journeys and for national policy at this critical moment in American civic life At a moment when our nation is once again bitterly divided around matters at the heart of American civic life, Race and Social Change: A Quest, A Study, A Call to Action seeks to push our collective journey forward with insights that promise to promote insight, understanding, and healing.
Bouchaib Radi Fluid-Structure Interactions and Uncertainties. Ansys and Fluent Tools Bouchaib Radi Fluid-Structure Interactions and Uncertainties. Ansys and Fluent Tools Новинка

Bouchaib Radi Fluid-Structure Interactions and Uncertainties. Ansys and Fluent Tools

9373.54 руб.
This book is dedicated to the general study of fluid structure interaction with consideration of uncertainties. The fluid-structure interaction is the study of the behavior of a solid in contact with a fluid, the response can be strongly affected by the action of the fluid. These phenomena are common and are sometimes the cause of the operation of certain systems, or otherwise manifest malfunction. The vibrations affect the integrity of structures and must be predicted to prevent accelerated wear of the system by material fatigue or even its destruction when the vibrations exceed a certain threshold.
Victoria Wapf The Disease of Chopin. A comprehensive study of a lifelong suffering Victoria Wapf The Disease of Chopin. A comprehensive study of a lifelong suffering Новинка

Victoria Wapf The Disease of Chopin. A comprehensive study of a lifelong suffering

480 руб.
The life of the Polish-French pianist and composer Frédéric Chopin (1810—1849) was, to a great extent, influenced by his disease. Nevertheless, the diagnosis and differential diagnoses of his suffering remain a matter of debates in numerous biographical studies on the composer’s life. This study shall conduct a systematization and overview of Chopin’s medical history, in an effort to outline pathways to his most probable diagnosis.
Jim Cullen Essaying the Past. How to Read, Write, and Think about History Jim Cullen Essaying the Past. How to Read, Write, and Think about History Новинка

Jim Cullen Essaying the Past. How to Read, Write, and Think about History

1870.44 руб.
Part research manual, part study guide, and part introduction to the study of history, Essaying the Past guides the reader through the nuts and bolts of producing good historical prose, offering key strategies and useful tips. Includes expert advice on writing about history, conducting good research, and learning how to think analytically Covers important topics such as framing questions, developing a strong introduction and topic sentences, choosing good evidence, and the crucial role of revision An annotated case study takes the reader through one student’s process of writing an essay and illustrates how strategies discussed in the book can be successfully implemented Six appendices cover the major issues facing students today, such as the dangers of plagiarism and the role of the internet
Salah Khalfallah Structural Analysis 2. Statically Indeterminate Structures Salah Khalfallah Structural Analysis 2. Statically Indeterminate Structures Новинка

Salah Khalfallah Structural Analysis 2. Statically Indeterminate Structures

15402.63 руб.
This book enables the student to master the methods of analysis of isostatic and hyperstatic structures. To show the performance of the methods of analysis of the hyperstatic structures, some beams, gantries and reticular structures are selected and subjected to a comparative study by the different methods of analysis of the hyperstatic structures. This procedure provides an insight into the methods of analysis of the structures.
Kevin Schilbrack Philosophy and the Study of Religions. A Manifesto Kevin Schilbrack Philosophy and the Study of Religions. A Manifesto Новинка

Kevin Schilbrack Philosophy and the Study of Religions. A Manifesto

7195.75 руб.
Philosophy and the Study of Religions: A Manifesto advocates a radical transformation of the discipline from its current, narrow focus on questions of God, to a fully global form of critical reflection on religions in all their variety and dimensions. Opens the discipline of philosophy of religion to the religious diversity that characterizes the world today Builds bridges between philosophy of religion and the other interpretative and explanatory approaches in the field of religious studies Provides a manifesto for a global approach to the subject that is a practice-centred rather than a belief-centred activity Gives attention to reflexive critical studies of 'religion' as socially constructed and historically located
Patrice Bailly Materials and Structures under Shock and Impact Patrice Bailly Materials and Structures under Shock and Impact Новинка

Patrice Bailly Materials and Structures under Shock and Impact

11623.19 руб.
In risk studies, engineers often have to consider the consequences of an accident leading to a shock on a construction. This can concern the impact of a ground vehicle or aircraft, or the effects of an explosion on an industrial site. This book presents a didactic approach starting with the theoretical elements of the mechanics of materials and structures, in order to develop their applications in the cases of shocks and impacts. The latter are studied on a local scale at first. They lead to stresses and strains in the form of waves propagating through the material, this movement then extending to the whole of the structure. The first part of the book is devoted to the study of solid dynamics where nonlinear behaviors come into play. The second part covers structural dynamics and the evaluation of the transient response introduced at the global scale of a construction. Practical methods, simplified methods and methods that are in current use by engineers are also proposed throughout the book. The aim of this book is to present theoretical elements regarding solids and structures, as well as modeling tools in order to study the vulnerability of a structure to a short duration action, generally of accidental nature. The book takes the point of view of an engineer seeking for the modeling of the physics at stake to relevantly carry out his study. The book originality is that it gathers elements from various fields of engineering sciences, for the purpose of a practical objective.
Вікторія Манагарова Проблема трансформації людини. Metamodernism/ Post.metamodernism. перше наукове дослідження в Україні (2015—2018) Вікторія Манагарова Проблема трансформації людини. Metamodernism/ Post.metamodernism. перше наукове дослідження в Україні (2015—2018) Новинка

Вікторія Манагарова Проблема трансформації людини. Metamodernism/ Post.metamodernism. перше наукове дослідження в Україні (2015—2018)

490 руб.
The relevance of this study opens up the possibility for “Elusive Man” of metamodernism to discover the path of truth, to see “plus” without “minus”, finishing the binary experience of wars and sufferings forever, opening a face of “Light Man” who lives under the laws of the “shades of goodness”, forming a new cultural condition of “post metamodernism”.*the language of the research is Ukrainian.
Timothy Barnes D. Constantine. Dynasty, Religion and Power in the Later Roman Empire Timothy Barnes D. Constantine. Dynasty, Religion and Power in the Later Roman Empire Новинка

Timothy Barnes D. Constantine. Dynasty, Religion and Power in the Later Roman Empire

11169.98 руб.
Drawing on recent scholarly advances and new evidence, Timothy Barnes offers a fresh and exciting study of Constantine and his life. First study of Constantine to make use of Kevin Wilkinson's re-dating of the poet Palladas to the reign of Constantine, disproving the predominant scholarly belief that Constantine remained tolerant in matters of religion to the end of his reign Clearly sets out the problems associated with depictions of Constantine and answers them with great clarity Includes Barnes' own research into the marriage of Constantine's parents, Constantine's status as a crown prince and his father's legitimate heir, and his dynastic plans Honorable Mention for 2011 Classics & Ancient History PROSE award granted by the Association of American Publishers
Lappin Shalom Linguistic Nativism and the Poverty of the Stimulus Lappin Shalom Linguistic Nativism and the Poverty of the Stimulus Новинка

Lappin Shalom Linguistic Nativism and the Poverty of the Stimulus

9486.62 руб.
This unique contribution to the ongoing discussion of language acquisition considers the Argument from the Poverty of the Stimulus in language learning in the context of the wider debate over cognitive, computational, and linguistic issues. Critically examines the Argument from the Poverty of the Stimulus – the theory that the linguistic input which children receive is insufficient to explain the rich and rapid development of their knowledge of their first language(s) through general learning mechanisms Focuses on formal learnability properties of the class of natural languages, considered from the perspective of several learning theoretic models The only current book length study of arguments for the poverty of the stimulus which focuses on the computational learning theoretic aspects of the problem
Francis X. Clooney, SJ Comparative Theology. Deep Learning Across Religious Borders Francis X. Clooney, SJ Comparative Theology. Deep Learning Across Religious Borders Новинка

Francis X. Clooney, SJ Comparative Theology. Deep Learning Across Religious Borders

2174.26 руб.
Drawing upon the author’s three decades of work in comparative theology, this is a pertinent and comprehensive introduction to the field, which offers a clear guide to the reader, enabling them to engage in comparative study. The author has three decades of experience of work in the field of comparative theology and is ideally placed to write this book Today’s increasing religious diversity makes this a pertinent and timely publication Unique in the depth of its introduction and explanation of the discipline of ‘comparative theology’ Provides examples of how comparative theology works in the new global context of human religiosity Draws on examples specific to Hindu-Christian studies to show how it is possible to understand more deeply the wider diversity around us. Clearly guides the reader, enabling them to engage in comparative study

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This book presents a comprehensive overview of the first longitudinal study of the downstream response of a major river to the establishment of a large hydropower facility and dams. Peace River, a northward flowing boreal river in northwestern Canada was dammed in 1967 and the book describes the morphological response of the 1200 km downstream channel and the response of riparian vegetation to the change in flow regime over the first forty years of regulated flows. Beginning with a description of the effect of regulation on the flow and sediment regimes of the river, the book proceeds to study changes in downstream channel geometry on the main stem, on the lowermost course of tributaries, and on the hydraulic geometry, the overall morphology of the channel, and riparian vegetation succession. The river is subject to annual freeze-up and break-up, so a chapter is devoted to the ice regime of the river. A chapter compares the effects of two extraordinary post-regulation flood events. The penultimate chapter presents a prediction of the ultimate equilibrium form of the regulated river based on rational regime theory. An online database of all the main observations will provide invaluable material for advanced students of river hydraulics and geomorphology. This book carefully brings together a range of studies that have been previously inaccessible providing a rare and comprehensive analysis of the effects of a big dam on a river, a river that itself represents an example of the kind of system that is likely to receive considerable attention in the future from dam engineers and environmentalists. • An invaluable reference to river scientists, hydroelectric power developers, engineers and environmentalists • Focus on a northward flowing boreal river, a type that holds most of the remaining hydroelectric power potential in the Northern Hemisphere • Exceptional separation of water and sediment sources, permitting study of the isolated effect of manipulating one of the two major governing conditions of river processes and form • Unique example of water regulation and both natural and engineered flood flows • Detailed study of both morphological changes of the channel and of the riparian vegetation • Online data supplement including major data tables and numerous maps. Details of the main observations and provides material for problem study by advanced students of river hydraulics and geomorphology are provided
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