uversky vladimir instrumental analysis of intrinsically disordered proteins assessing structure and conformation



Uversky Vladimir Instrumental Analysis of Intrinsically Disordered Proteins. Assessing Structure and Conformation Uversky Vladimir Instrumental Analysis of Intrinsically Disordered Proteins. Assessing Structure and Conformation Новинка

Uversky Vladimir Instrumental Analysis of Intrinsically Disordered Proteins. Assessing Structure and Conformation

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Instrumental techniques for analyzing intrinsically disordered proteins The recently recognized phenomenon of protein intrinsic disorder is gaining significant interest among researchers, especially as the number of proteins and protein domains that have been shown to be intrinsically disordered rapidly grows. The first reference to tackle this little-documented area, Instrumental Analysis of Intrinsically Disordered Proteins: Assessing Structure and Conformation provides researchers with a much-needed, comprehensive summary of recent achievements in the methods for structural characterization of intrinsically disordered proteins (IDPs). Chapters discuss: Assessment of IDPs in the living cell Spectroscopic techniques for the analysis of IDPs, including NMR and EPR spectroscopies, FTIR, circular dichroism, fluorescence spectroscopy, vibrational methods, and single-molecule analysis Single-molecule techniques applied to the study of IDPs Assessment of IDP size and shape Tools for the analysis of IDP conformational stability Mass spectrometry Approaches for expression and purification of IDPs With contributions from an international selection of leading researchers, Instrumental Analysis of Intrinsically Disordered Proteins: Assessing Structure and Conformation fills an important need in a rapidly growing field. It is required reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, physiologists, and specialists in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.
Uversky Vladimir Protein and Peptide Folding, Misfolding, and Non-Folding Uversky Vladimir Protein and Peptide Folding, Misfolding, and Non-Folding Новинка

Uversky Vladimir Protein and Peptide Folding, Misfolding, and Non-Folding

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Sheds new light on intrinsically disordered proteins and peptides, including their role in neurodegenerative diseases With the discovery of intrinsically disordered proteins and peptides (IDPs), researchers realized that proteins do not necessarily adopt a well defined secondary and tertiary structure in order to perform biological functions. In fact, IDPs play biologically relevant roles, acting as inhibitors, scavengers, and even facilitating DNA/RNA-protein interactions. Due to their propensity for self-aggregation and fibril formation, some IDPs are involved in neurodegenerative diseases such as Parkinson's and Alzheimer's. With contributions from leading researchers, this text reviews the most recent studies, encapsulating our understanding of IDPs. The authors explain how the growing body of IDP research is building our knowledge of the folding process, the binding of ligands to receptor molecules, and peptide self-aggregation. Readers will discover a variety of experimental, theoretical, and computational approaches used to better understand the properties and function of IDPs. Moreover, they'll discover the role of IDPs in human disease and as drug targets. Protein and Peptide Folding, Misfolding, and Non-Folding begins with an introduction that explains why research on IDPs has significantly expanded in the past few years. Next, the book is divided into three sections: Conformational Analysis of Unfolded States Disordered Peptides and Molecular Recognition Aggregation of Disordered Peptides Throughout the book, detailed figures help readers understand the structure, properties, and function of IDPs. References at the end of each chapter serve as a gateway to the growing body of literature in the field. With the publication of Protein and Peptide Folding, Misfolding, and Non-Folding, researchers now have a single place to discover IDPs, their diverse biological functions, and the many disciplines that have contributed to our evolving understanding of them.
David Weis D. Hydrogen Exchange Mass Spectrometry of Proteins. Fundamentals, Methods, and Applications David Weis D. Hydrogen Exchange Mass Spectrometry of Proteins. Fundamentals, Methods, and Applications Новинка

David Weis D. Hydrogen Exchange Mass Spectrometry of Proteins. Fundamentals, Methods, and Applications

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Hydrogen exchange mass spectrometry is widely recognized for its ability to probe the structure and dynamics of proteins. The application of this technique is becoming widespread due to its versatility for providing structural information about challenging biological macromolecules such as antibodies, flexible proteins and glycoproteins. Although the technique has been around for 25 years, this is the first definitive book devoted entirely to the topic. Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods and Applications brings into one comprehensive volume the theory, instrumentation and applications of Hydrogen Exchange Mass Spectrometry (HX-MS) – a technique relevant to bioanalytical chemistry, protein science and pharmaceuticals. The book provides a solid foundation in the basics of the technique and data interpretation to inform readers of current research in the method, and provides illustrative examples of its use in bio- and pharmaceutical chemistry and biophysics In-depth chapters on the fundamental theory of hydrogen exchange, and tutorial chapters on measurement and data analysis provide the essential background for those ready to adopt HX-MS. Expert users may advance their current understanding through chapters on methods including membrane protein analysis, alternative proteases, millisecond hydrogen exchange, top-down mass spectrometry, histidine exchange and method validation. All readers can explore the diversity of HX-MS applications in areas such as ligand binding, membrane proteins, drug discovery, therapeutic protein formulation, biocomparability, and intrinsically disordered proteins.
Lian Lu-Yun Protein NMR Spectroscopy. Practical Techniques and Applications Lian Lu-Yun Protein NMR Spectroscopy. Practical Techniques and Applications Новинка

Lian Lu-Yun Protein NMR Spectroscopy. Practical Techniques and Applications

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Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. The dramatic advances in NMR techniques have led to corresponding advances in the ability of NMR to study structure, dynamics and interactions of biological macromolecules in solution under close to physiological conditions. This volume focuses on the use of NMR to study proteins. NMR can be used to determine detailed three-dimensional structures of proteins in solution. Furthermore, it provides information about conformational or chemical exchange, internal mobility and dynamics at timescales varying from pcoseconds to seconds. It is the primary technique used to obtain information on intrinsically disordered (unfolded) proteins, since these proteins will not crystallize easily. NMR is also a very powerful method for the study of interactions of protein with other molecules, whether small molecules (including drugs), nuclear acids or other proteins. This up-to-date volume covers NMR techiniques and their application to proteins, with a focus on practical details. This book will provide a newcomer to NMR with the practical guidance in order to carry out successful experiments with proteins and to analyze the resulting spectra. Those who are familiar with the chemical applications of NMR will also find is useful in understanding the special requirements of protien NMR.
Uversky Vladimir Flexible Viruses. Structural Disorder in Viral Proteins Uversky Vladimir Flexible Viruses. Structural Disorder in Viral Proteins Новинка

Uversky Vladimir Flexible Viruses. Structural Disorder in Viral Proteins

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This book provides up-to-date information on experimental and computational characterization of the structural and functional properties of viral proteins, which are widely involved in regulatory and signaling processes. With chapters by leading research groups, it features current information on the structural and functional roles of intrinsic disorders in viral proteomes. It systematically addresses the measles, HIV, influenza, potato virus, forest virus, bovine virus, hepatitis, and rotavirus as well as viral genomics. After analyzing the unique features of each class of viral proteins, future directions for research and disease management are presented.
Lappi Douglas Ribosome-inactivating Proteins. Ricin and Related Proteins Lappi Douglas Ribosome-inactivating Proteins. Ricin and Related Proteins Новинка

Lappi Douglas Ribosome-inactivating Proteins. Ricin and Related Proteins

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This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.
Finizia Auriemma Crystals and Crystallinity in Polymers. Diffraction Analysis of Ordered and Disordered Crystals Finizia Auriemma Crystals and Crystallinity in Polymers. Diffraction Analysis of Ordered and Disordered Crystals Новинка

Finizia Auriemma Crystals and Crystallinity in Polymers. Diffraction Analysis of Ordered and Disordered Crystals

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Provides the tools needed to master and apply the fundamentals of polymer crystallography Using core concepts in physics, chemistry, polymer science and engineering, this book sheds new light on the complex field of polymer crystallography, enabling readers to evaluate polymer crystallization data and determine the best methods to use for their investigations. The authors set forth a variety of tested and proven methods for analyzing ordered and disordered structures in polymer crystals, including X-ray diffraction, electron diffraction, and microscopy. In addition to the basics, the book explores several advanced and emerging topics in the field such as symmetry breaking, frustration, and the principle of density-driven phase formation. Crystals and Crystallinity in Polymers introduces two new concepts in crystallinity and crystals in synthetic polymers. First, crystallinity in polymeric materials is compatible with the absence of true three-dimensional long-range order. Second, the disorder may be described as a structural feature, using the methods of X-ray scattering and electron diffraction analysis. The book begins by introducing the basic principles and methods for building structural models for the conformation of polymer crystal chains. Next, it covers: Packing of macromolecules in polymer crystals Methods for extracting structural parameters from diffraction data Defects and disorder in polymer crystals Analytical methods for diffuse scattering from disordered polymer structures Crystal habit Influence of crystal defects and structural disorder on the physical and mechanical properties of polymeric materials Crystals and Crystallinity in Polymers examines all the possible types of structural disorder generally present in polymer crystals and describes the influence of each kind of disorder on X-ray and electron diffraction patterns. Its comprehensive, expert coverage makes it possible for readers to learn and apply the fundamentals of polymer crystallography to solve a broad range of problems.
Daniel Chateigner Combined Analysis Daniel Chateigner Combined Analysis Новинка

Daniel Chateigner Combined Analysis

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This book introduces and details the key facets of Combined Analysis – an x-ray and/or neutron scattering methodology which combines structural, textural, stress, microstructural, phase, layer, or other relevant variable or property analyses in a single approach. The text starts with basic theories related to diffraction by polycrystals and some of the most common combined analysis instrumental set-ups are detailed. Also discussed are microstructures of powder diffraction profiles; quantitative phase analysis from the Rietveld analysis; residual stress analysis for isotropic and anisotropic materials; specular x-ray reflectivity, and the various associated models.
Piñeiro Ángel Proteins in Solution and at Interfaces. Methods and Applications in Biotechnology and Materials Science Piñeiro Ángel Proteins in Solution and at Interfaces. Methods and Applications in Biotechnology and Materials Science Новинка

Piñeiro Ángel Proteins in Solution and at Interfaces. Methods and Applications in Biotechnology and Materials Science

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Explores new applications emerging from our latest understanding of proteins in solution and at interfaces Proteins in solution and at interfaces increasingly serve as the starting point for exciting new applications, from biomimetic materials to nanoparticle patterning. This book surveys the state of the science in the field, offering investigators a current understanding of the characteristics of proteins in solution and at interfaces as well as the techniques used to study these characteristics. Moreover, the authors explore many of the new and emerging applications that have resulted from the most recent studies. Topics include protein and protein aggregate structure; computational and experimental techniques to study protein structure, aggregation, and adsorption; proteins in non-standard conditions; and applications in biotechnology. Proteins in Solution and at Interfaces is divided into two parts: Part One introduces concepts as well as theoretical and experimental techniques that are used to study protein systems, including X-ray crystallography, nuclear magnetic resonance, small angle scattering, and spectroscopic methods Part Two examines current and emerging applications, including nanomaterials, natural fibrous proteins, and biomolecular thermodynamics The book's twenty-three chapters have been contributed by leading experts in the field. These contributions are based on a thorough review of the latest peer-reviewed findings as well as the authors' own research experience. Chapters begin with a discussion of core concepts and then gradually build in complexity, concluding with a forecast of future developments. Readers will not only gain a current understanding of proteins in solution and at interfaces, but also will discover how theoretical and technical developments in the field can be translated into new applications in material design, genetic engineering, personalized medicine, drug delivery, biosensors, and biotechnology.
Vladimir Havlicek Natural Products Analysis. Instrumentation, Methods, and Applications Vladimir Havlicek Natural Products Analysis. Instrumentation, Methods, and Applications Новинка

Vladimir Havlicek Natural Products Analysis. Instrumentation, Methods, and Applications

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This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products. • Applies analytical techniques to natural products research – an area of critical importance to drug discovery • Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics • Includes coverage of natural products basics and highlights antibacterial research, particularly important as efforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail for both current practitioners and beginning researchers
Eveline Litscher S. A Guide to Zona Pellucida Domain Proteins Eveline Litscher S. A Guide to Zona Pellucida Domain Proteins Новинка

Eveline Litscher S. A Guide to Zona Pellucida Domain Proteins

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This book provides a coherent, clear, and uniform presentation of structural, genetic, molecular, and biochemical information available for the zona pellucida domain protein family, which impact pathologies such as infertility, deafness, and cancer. Furthermore it: Details information about the structure and function of the ZP domain in ZPDC-proteins Provides illustrations of the organization of ZPDC-proteins, the genes that encode the proteins, and examples of mutations in the ZP domain that cause diseases Speculates as to the evolution of the ZP domain and potential therapeutics for diseases stemming from ZP domain mutations Addresses mammalian and non-mammalian systems
Ю. В. Лысенко Analysis technique and risk assessment of insolvency of machine-building enterprise Ю. В. Лысенко Analysis technique and risk assessment of insolvency of machine-building enterprise Новинка

Ю. В. Лысенко Analysis technique and risk assessment of insolvency of machine-building enterprise

The monograph is devoted to a problem of production and sale of the concentrating and mountain equipment. The economic evaluation of production and sale is opened in the following sequence. The economic essence of the concept «insolvency» of the entity is stated. The reasons of risk of insolvency, its role in diagnostic approaches to solvency analysis of the entity, are called and analysed possibilities of a risk assessment of insolvency of the entity. By means of assessment of a condition the model of the analysis and a risk assessment of insolvency of the entity, an algorithm of its application in the analysis of machine-building enterprise is developed. Assessment of a condition of production and sale is carried out based on huge statistical material on influence of structure and structure of current assets on solvency of machinebuilding enterprise, liquidity of balance and assessment of liquidity and efficiency of cash flows for strengthening and optimization of activities. With use of integration of methods approbation of an analysis technique and a risk assessment of insolvency of machine-building enterprise is carried out and the possibilities of its optimization are considered. In an analysis result, assessment and developed offers the management concept is formulated by liquidity of machine-building enterprise and decrease in risk of insolvency, the principles of its forming and the mechanism of implementation are shown.
Raynor Mark W. Trace Analysis of Specialty and Electronic Gases Raynor Mark W. Trace Analysis of Specialty and Electronic Gases Новинка

Raynor Mark W. Trace Analysis of Specialty and Electronic Gases

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Explores the latest advances and applications of specialty and electronic gas analysis The semiconductor industry depends upon a broad range of instrumental techniques in order to detect and analyze impurities that may be present in specialty and electronic gases, including permanent gases, water vapor, reaction by-products, and metal species. Trace Analysis of Specialty and Electronic Gases draws together all the latest advances in analytical chemistry, providing researchers with both the theory and the operating principles of the full spectrum of instrumental techniques available for specialty and electronic gas analysis. Moreover, the book details the advantages and disadvantages of each technique, steering readers away from common pitfalls. Featuring contributions from leading analytical and industrial chemists, Trace Analysis of Specialty and Electronic Gases covers a wide range of practical industrial applications. The book begins with the historical development of gas analysis and then focuses on particular subjects or techniques such as: Metals sampling and ICP-MS analysis Improvements in FTIR spectroscopy Water vapor analysis techniques New infrared laser absorption spectroscopy approaches GC/MS, GC/AED, and GC-ICP-MS techniques Gas chromatography columns Atmospheric pressure ionization mass spectrometry Lastly, the book examines gas mixtures and standards that are critical for instrument calibration. There are also two appendices offering information on fittings and material compatibility. With its thorough review of the literature and step-by-step guidance, Trace Analysis of Specialty and Electronic Gases enables researchers to take full advantage of the latest advances in gas analysis. Although the book's focus is the semiconductor and electronics industry, analytical chemists in other industries facing challenges with such issues as detection selectivity and sensitivity, matrix gas interference, and materials compatibility will also discover plenty of useful analytical approaches and techniques.
Peter Privalov L. Microcalorimetry of Macromolecules. The Physical Basis of Biological Structures Peter Privalov L. Microcalorimetry of Macromolecules. The Physical Basis of Biological Structures Новинка

Peter Privalov L. Microcalorimetry of Macromolecules. The Physical Basis of Biological Structures

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Examining the physical basis of the structure of macromolecules—proteins, nucleic acids, and their complexes—using calorimetric techniques Many scientists working in biology are unfamiliar with the basics of thermodynamics and its role in determining molecular structures. Yet measuring the heat of structural change a molecule undergoes under various conditions yields information on the energies involved and, thus, on the physical bases of the considered structures. Microcalorimetry of Macromolecules offers protein scientists unique access to this important information. Divided into thirteen chapters, the book introduces readers to the basics of thermodynamics as it applies to calorimetry, the evolution of the calorimetric technique, as well as how calorimetric techniques are used in the thermodynamic studies of macromolecules, detailing instruments for measuring the heat effects of various processes. Also provided is general information on the structure of biological macromolecules, proteins, and nucleic acids, focusing on the key thermodynamic problems relating to their structure. The book covers: The use of supersensitive calorimetric instruments, including micro and nano-calorimeters for measuring the heat of isothermal reactions (Isothermal Titration Nano-Calorimeter), the heat capacities over a broad temperature range (Scanning Nano-Calorimeter), and pressure effects (Pressure Perturbation Nano-Calorimeter) Two of the simplest but key structural elements: the α and polyproline helices and their complexes, the α-helical coiled-coil, and the pyroline coiled-coils Complicated macromolecular formations, including small globular proteins, multidomain proteins and their complexes, and nucleic acids Numerous examples of measuring the ground state of protein energetics, as well as changes seen when proteins interact The book also reveals how intertwined structure and thermodynamics are in terms of a macromolecule's organization, mechanism of formation, the stabilization of its three-dimensional structure, and ultimately, its function. The first book to describe microcalorimetric technique in detail, enough for graduate students and research scientists to successfully plumb the structural mysteries of proteins and the double helix, Microcalorimetry of Macromolecules is an essential introduction to using a microcalorimeter in biological studies.
Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient Новинка

Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient

13300.89 руб. или Купить в рассрочку!
Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs , instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives Brings together the most current advances in the mass spectrometry technology and related method in protein analysis
Brian Henderson Moonlighting Proteins. Novel Virulence Factors in Bacterial Infections Brian Henderson Moonlighting Proteins. Novel Virulence Factors in Bacterial Infections Новинка

Brian Henderson Moonlighting Proteins. Novel Virulence Factors in Bacterial Infections

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Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science. About the Editor Brian Henderson, Division of Infection and Immunity, University College London, London, UK
Birendra Pramanik Protein and Peptide Mass Spectrometry in Drug Discovery Birendra Pramanik Protein and Peptide Mass Spectrometry in Drug Discovery Новинка

Birendra Pramanik Protein and Peptide Mass Spectrometry in Drug Discovery

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The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.
Michael McMillan Investments. Principles of Portfolio and Equity Analysis Michael McMillan Investments. Principles of Portfolio and Equity Analysis Новинка

Michael McMillan Investments. Principles of Portfolio and Equity Analysis

6467.94 руб. или Купить в рассрочку!
A comprehensive guide to investment analysis and portfolio management by an expert team from the CFA Institute In a world of specialization, no other profession likely requires such broad, yet in-depth knowledge than that of financial analyst. Financial analysts must not only possess a broad understanding of the financial markets-including structure, organization, efficiency, portfolio management, risk and return, and planning and construction-but they must also have a strong sense of how to evaluate industries and companies prior to engaging in an analysis of a specific stock. Investments: Principles of Portfolio and Equity Analysis provides the broad-based knowledge professionals and students of the markets need to manage money and maximize return. The book Details market structure and functions, market anomalies, secondary market basics, and regulation Describes investment assets and asset classes, types of positions and orders, as well as forecasting methodologies Discusses return and risk characteristics, portfolio diversification and management, the basics of both technical analysis and major technical indicators, and much more A companion Workbook, which includes learning outcomes, summary overviews, and problems and solutions sections is available and sold separately Investments provides readers unparalleled access to the best in professional quality information on investment analysis and portfolio management.
Dermot O'Hare Structure from Diffraction Methods. Inorganic Materials Series Dermot O'Hare Structure from Diffraction Methods. Inorganic Materials Series Новинка

Dermot O'Hare Structure from Diffraction Methods. Inorganic Materials Series

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Inorganic materials show a diverse range of important properties that are desirable for many contemporary, real-world applications. Good examples include recyclable battery cathode materials for energy storage and transport, porous solids for capture and storage of gases and molecular complexes for use in electronic devices. An understanding of the function of these materials is necessary in order to optimise their behaviour for real applications, hence the importance of 'structure–property relationships'. The chapters presented in this volume deal with recent advances in the characterisation of crystalline materials. They include some familiar diffraction methods, thoroughly updated with modern advances. Also included are techniques that can now probe details of the three-dimensional arrangements of atoms in nanocrystalline solids, allowing aspects of disorder to be studied. Small-angle scattering, a technique that is often overlooked, can probe both ordered and disordered structures of materials at longer length scales than those probed by powder diffraction methods. Addressing both physical principals and recent advances in their applications, Structure from Diffraction Methods covers: Powder Diffraction X-Ray and Neutron Single-Crystal Diffraction PDF Analysis of Nanoparticles Electron Crystallography Small-Angle Scattering Ideal as a complementary reference work to other volumes in the series (Local Structural Characterisation and Multi Length-Scale Characterisation), or as an examination of the specific characterisation techniques in their own right, Structure from Diffraction Methods is a valuable addition to the Inorganic Materials Series.
Zeynep Ustunol Applied Food Protein Chemistry Zeynep Ustunol Applied Food Protein Chemistry Новинка

Zeynep Ustunol Applied Food Protein Chemistry

15653.88 руб. или Купить в рассрочку!
Food proteins are of great interest, not only because of their nutritional importance and their functionality in foods, but also for their detrimental effects. Although proteins from milk, meats (including fish and poultry), eggs, cereals, legumes, and oilseeds have been the traditional sources of protein in the human diet, potentially any proteins from a biological source could serve as a food protein. The primary role of protein in the diet is to provide the building materials for the synthesis of muscle and other tissues, and they play a critical role in many biological processes. They are also responsible for food texture, color, and flavor. Today, food proteins are extracted, modified, and incorporated into processed foods to impart specific functional properties. They can also have adverse effects in the diet: proteins, such as walnuts, pecans, almonds, and cashews, soybean, wheat, milk, egg, crustacean, and fish proteins can be powerful allergens for some people. Applied Food Protein Chemistry is an applied reference which reviews the properties of food proteins and provides in-depth information on important plant and animal proteins consumed around the world. The book is grouped into three sections: (1) overview of food proteins, (2) plant proteins, and (3) animal proteins. Each chapter discusses world production, distribution, utilization, physicochemical properties, and the functional properties of each protein, as well as its food applications. The authors for each of the chapters are carefully selected experts in the field. This book will be a valuable reference tool for those who work on food proteins. It will also be an important text on applied food protein chemistry for upper-level students and graduate students of food science programs.
Kretsinger Robert H. Calcium Binding Proteins Kretsinger Robert H. Calcium Binding Proteins Новинка

Kretsinger Robert H. Calcium Binding Proteins

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Calcium Binding Proteins explains the unique and highly diverse functions of calcium in biology, which are realized by calcium binding proteins. The structures and physical characteristics of these calcium binding proteins are described, as well as their functions and general patterns of their evolution. Techniques that underlie the description of proteins are discussed, including NMR, circular dichroism, optical rotatory dispersion spectroscopy, calorimetry,and crystallography. The book discusses the patterns of bochmical phenomena such as calcium homeostasis, mineralization, and cell signaling that involve specific proteins. It summarizes ongoing research and presents general hypotheses that help to focus future research, and also provides a conceptual framework and a description of the underlying techniques that permits someone entering the field to become conversant.
Victor Rudenno The Mining Valuation Handbook. Mining and Energy Valuation for Investors and Management Victor Rudenno The Mining Valuation Handbook. Mining and Energy Valuation for Investors and Management Новинка

Victor Rudenno The Mining Valuation Handbook. Mining and Energy Valuation for Investors and Management

10866.14 руб. или Купить в рассрочку!
The essential guide to investing in mining opportunities, now in its Fourth Edition A comprehensive guide to mining investment analysis designed for use by financial and mining analysts, executives, and investors, The Mining Valuation Handbook: Mining and Energy Valuation for Investors and Management has become an essential resource for assessing the value and investment potential of mining opportunities. Fully revised and updated, this fourth edition of the classic text provides new and up-to-date information to better explain the mysteries surrounding the resources industry. Written by Victor Rudenno, a leading global expert on mining investment analysis and consultant to mining companies, financial bodies, and governments, The Mining Valuation Handbook: Mining and Energy Valuation for Investors and Management, Fourth Edition covers a wide range of essential topics, including: feasibility studies, commodity values and forecasting, classification of resources and reserves, indicative capital and operating costs, valuation and pricing techniques, qualifying risk, the impact of exploration and expansion, and more. Fourth edition of the bestselling text on assessing mining investment opportunities Author Victor Rudenno is a respected global expert on mining investment analysis Key topics, including feasibility studies, valuation techniques, and risk qualification are covered in detail Packed with invaluable mining information for the financial industry and financial information for the mining industry, The Mining Valuation Handbook is the definitive guide to assessing and investing in mining opportunities.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Analysis and Function of Amino Acids and Peptides

17773.9 руб. или Купить в рассрочку!
This is the last of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides Volume 5 of this series presents a wealth of methods to analyze amino acids and peptides. Classical approaches are described, such as X-ray analysis, chromatographic methods, NMR, AFM, mass spectrometry and 2D-gel electrophoresis, as well as newer approaches, including Surface Plasmon Resonance and array technologies. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Dominique Sportiche An Introduction to Syntactic Analysis and Theory Dominique Sportiche An Introduction to Syntactic Analysis and Theory Новинка

Dominique Sportiche An Introduction to Syntactic Analysis and Theory

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An Introduction to Syntactic Analysis and Theory offers beginning students a comprehensive overview of and introduction to our current understanding of the rules and principles that govern the syntax of natural languages. Includes numerous pedagogical features such as ‘practice’ boxes and sidebars, designed to facilitate understanding of both the ‘hows’ and the ‘whys’ of sentence structure Guides readers through syntactic and morphological structures in a progressive manner Takes the mystery out of one of the most crucial aspects of the workings of language – the principles and processes behind the structure of sentences Ideal for students with minimal knowledge of current syntactic research, it progresses in theoretical difficulty from basic ideas and theories to more complex and advanced, up to date concepts in syntactic theory
Eric Johnson R. Handbook of Decision Analysis Eric Johnson R. Handbook of Decision Analysis Новинка

Eric Johnson R. Handbook of Decision Analysis

12541.56 руб. или Купить в рассрочку!
A ONE-OF-A-KIND GUIDE TO THE BEST PRACTICES IN DECISION ANALYSIS Decision analysis provides powerful tools for addressing complex decisions that involve uncertainty and multiple objectives, yet most training materials on the subject overlook the soft skills that are essential for success in the field. This unique resource fills this gap in the decision analysis literature and features both soft personal/interpersonal skills and the hard technical skills involving mathematics and modeling. Readers will learn how to identify and overcome the numerous challenges of decision making, choose the appropriate decision process, lead and manage teams, and create value for their organization. Performing modeling analysis, assessing risk, and implementing decisions are also addressed throughout. Additional features include: Key insights gleaned from decision analysis applications and behavioral decision analysis research Integrated coverage of the techniques of single- and multiple-objective decision analysis Multiple qualitative and quantitative techniques presented for each key decision analysis task Three substantive real-world case studies illustrating diverse strategies for dealing with the challenges of decision making Extensive references for mathematical proofs and advanced topics The Handbook of Decision Analysis is an essential reference for academics and practitioners in various fields including business, operations research, engineering, and science. The book also serves as a supplement for courses at the upper-undergraduate and graduate levels.
T. Datta K. Seismic Analysis of Structures T. Datta K. Seismic Analysis of Structures Новинка

T. Datta K. Seismic Analysis of Structures

13194.6 руб. или Купить в рассрочку!
While numerous books have been written on earthquakes, earthquake resistance design, and seismic analysis and design of structures, none have been tailored for advanced students and practitioners, and those who would like to have most of the important aspects of seismic analysis in one place. With this book, readers will gain proficiencies in the following: fundamentals of seismology that all structural engineers must know; various forms of seismic inputs; different types of seismic analysis like, time and frequency domain analyses, spectral analysis of structures for random ground motion, response spectrum method of analysis; equivalent lateral load analysis as given in earthquake codes; inelastic response analysis and the concept of ductility; ground response analysis and seismic soil structure interaction; seismic reliability analysis of structures; and control of seismic response of structures. Provides comprehensive coverage, from seismology to seismic control Contains useful empirical equations often required in the seismic analysis of structures Outlines explicit steps for seismic analysis of MDOF systems with multi support excitations Works through solved problems to illustrate different concepts Makes use of MATLAB, SAP2000 and ABAQUAS in solving example problems of the book Provides numerous exercise problems to aid understanding of the subject As one of the first books to present such a comprehensive treatment of the topic, Seismic Analysis of Structures is ideal for postgraduates and researchers in Earthquake Engineering, Structural Dynamics, and Geotechnical Earthquake Engineering. Developed for classroom use, the book can also be used for advanced undergraduate students planning for a career or further study in the subject area. The book will also better equip structural engineering consultants and practicing engineers in the use of standard software for seismic analysis of buildings, bridges, dams, and towers. Lecture materials for instructors available at www.wiley.com/go/dattaseismic
Alex Blaszczynski The Wiley-Blackwell Handbook of Disordered Gambling Alex Blaszczynski The Wiley-Blackwell Handbook of Disordered Gambling Новинка

Alex Blaszczynski The Wiley-Blackwell Handbook of Disordered Gambling

15581.05 руб. или Купить в рассрочку!
The Wiley-Blackwell Handbook of Disordered Gambling is a complete guide to the current empirical literature relating to the conceptualization, assessment, and treatment of disordered gambling. The international contributors are all experienced, practicing clinicians who discuss gambling within a global context. Best-practice guidelines for the clinical management of problem and disordered gambling Contains empirically derived findings that translate research into practical clinical applications that clinicians and counselors can use in understanding and treating problem gamblers Brings together a distinguished international group of scholars whose contributions discuss gambling as it occurs around the globe Clearly organized into sections that cover conceptualization, research, assessment, treatment, and special topics
Wendy Sandoval Analytical Characterization of Biotherapeutics Wendy Sandoval Analytical Characterization of Biotherapeutics Новинка

Wendy Sandoval Analytical Characterization of Biotherapeutics

14821.72 руб. или Купить в рассрочку!
The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics research Analytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions. In addition, it frames critical questions warranting attention in the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules, and presents a number of tested solutions. The first single-volume guide of its kind, Analytical Characterization of Biotherapeutics brings together contributions from scientists at the leading edge of biotherapeutics research and manufacturing. Key topics covered in-depth include the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or other hybrid molecules, characterization of manufacturing host-cell contaminant proteins, analytical tools for biologics molecular assessment, and more. Each chapter is written by a recognized expert or experts in their field who discuss current and cutting edge approaches to fully characterizing biotherapeutic proteins and antigen reagents Covers the full range of characterization strategies for large molecule based therapeutics Provides an up-to-date account of the latest approaches used for large molecule characterization Chapters cover the background needed to understand the challenges at hand, solutions to characterize these large molecules, and a summary of emerging options for analytical characterization Analytical Characterization of Biotherapeutics is an up-to-date resource for analytical scientists, biologists, and mass spectrometrists involved in the analysis of biomolecules, as well as scientists employed in the pharmaceuticals and biotechnology industries. Graduate students in biology and analytical science, and their instructors will find it to be fascinating and instructive supplementary reading.
Christian Lalanne Mechanical Vibration and Shock Analysis, Random Vibration Christian Lalanne Mechanical Vibration and Shock Analysis, Random Vibration Новинка

Christian Lalanne Mechanical Vibration and Shock Analysis, Random Vibration

15728.87 руб. или Купить в рассрочку!
The vast majority of vibrations encountered in the real environment are random in nature. Such vibrations are intrinsically complicated and this volume describes the process that enables us to simplify the required analysis, along with the analysis of the signal in the frequency domain. The power spectrum density is also defined, together with the requisite precautions to be taken in its calculations as well as the processes (windowing, overlapping) necessary to obtain improved results. An additional complementary method – the analysis of statistical properties of the time signal – is also described. This enables the distribution law of the maxima of a random Gaussian signal to be determined and simplifies the calculation of fatigue damage by avoiding direct peak counting.
Brian Henderson Protein Moonlighting in Biology and Medicine Brian Henderson Protein Moonlighting in Biology and Medicine Новинка

Brian Henderson Protein Moonlighting in Biology and Medicine

12917.98 руб. или Купить в рассрочку!
The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.
Brian Bennett T. Understanding, Assessing, and Responding to Terrorism. Protecting Critical Infrastructure and Personnel Brian Bennett T. Understanding, Assessing, and Responding to Terrorism. Protecting Critical Infrastructure and Personnel Новинка

Brian Bennett T. Understanding, Assessing, and Responding to Terrorism. Protecting Critical Infrastructure and Personnel

11642.29 руб. или Купить в рассрочку!
A comprehensive guide to understanding, assessing, and responding to terrorism in this modern age This book provides readers with a thorough understanding of the types of attacks that may be perpetrated, and how to identify potential targets, conduct a meaningful vulnerability analysis, and apply protective measures to secure personnel and facilities. The new edition of Understanding, Assessing, and Responding to Terrorism updates existing material and includes several new topics that have emerged, including information on new international terrorist groups as well as a new chapter on Regulations and Standards. A vulnerability analysis methodology, consisting of several steps—which include the techniques necessary to conduct a vulnerability analysis—is introduced and applied through several sample scenarios. By using easily customized templates for the screening process, valuation of a critical asset as a target, vulnerability analysis, security procedures, emergency response procedures, and training programs, the book offers a practical step-by-step process to help reduce risk. Each different type of terrorism is briefly discussed—however, the book focuses on those potential attacks that may involve weapons of mass destruction. There is a discussion of what physical and administrative enhancements can be implemented to improve a facility's ability to devalue, detect, deter, deny, delay, defend, respond, and recover to a real or threatened terrorist attack—whether it be at a facility, or in the community. Techniques on how personnel safety and security can be improved through the implementation of counter-terrorism programs are also outlined. An overview of the major counter-terrorism regulations and standards are presented, along with the significant governmental efforts that have been implemented to help prevent terrorist attacks and foster preparedness at both private and public sector facilities and for personnel. Understanding, Assessing, and Responding to Terrorism, Second Edition: Updates existing material, plus includes several new topics that have emerged including information on new international terrorist groups, new terrorist tactics, cyber terrorism, and Regulations and Standards Outlines techniques for improving facility and personnel safety and security through the implementation of counter-terrorism programs Unites the emergency response/public sector community with the private sector over infrastructure protection, thus allowing for easier communication between them Includes questions/exercises at the end of each chapter and a solutions manual to facilitate its use as a textbook Understanding, Assessing, and Responding to Terrorism, Second Edition is a must-have reference for private and public sector risk managers, safety engineers, security professionals, facility managers, emergency responders, and others charged with protecting facilities and personnel from all types of hazards (accidental, intentional, and natural).
Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting Новинка

Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting

13377.33 руб. или Купить в рассрочку!
The proteins that gather light for plant photosynthesis are embedded within cell membranes in a site called the thylakoid membrane (or the «photosynthetic membrane»). These proteins form the light harvesting antenna that feeds with energy a number of vital photosynthetic processes such as water oxidation and oxygen evolution, the pumping of protons across the thylakoid membranes coupled with the electron transport chain of the photosystems and cytochrome b6f complex, and ATP synthesis by ATP synthase utilizing the generated proton gradient. The Photosynthetic Membrane: Molecular Mechanisms and Biophysics of Light Harvesting is an introduction to the fundamental design and function of the light harvesting photosynthetic membrane, one of the most common and most important structures of life. It describes the underlying structure of the membrane, the variety and roles of the membrane proteins, the atomic structures of light harvesting complexes and their macromolecular assemblies, the molecular mechanisms and dynamics of light harvesting and primary energy transformations, and the broad range of adaptations to different light environments. The book shows, using the example of the photosynthetic membrane, how complex biological structures utilize principles of chemistry and physics in order to carry out biological functions. The Photosynthetic Membrane: Molecular Mechanisms of Light Harvesting will appeal to a wide audience of undergraduate and postgraduate students as well as researchers working in the fields of biochemistry, molecular biology, biophysics, plant science and bioengineering.
Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting Новинка

Alexander Ruban V. The Photosynthetic Membrane. Molecular Mechanisms and Biophysics of Light Harvesting

13660.29 руб. или Купить в рассрочку!
The proteins that gather light for plant photosynthesis are embedded within cell membranes in a site called the thylakoid membrane (or the «photosynthetic membrane»). These proteins form the light harvesting antenna that feeds with energy a number of vital photosynthetic processes such as water oxidation and oxygen evolution, the pumping of protons across the thylakoid membranes coupled with the electron transport chain of the photosystems and cytochrome b6f complex, and ATP synthesis by ATP synthase utilizing the generated proton gradient. The Photosynthetic Membrane: Molecular Mechanisms and Biophysics of Light Harvesting is an introduction to the fundamental design and function of the light harvesting photosynthetic membrane, one of the most common and most important structures of life. It describes the underlying structure of the membrane, the variety and roles of the membrane proteins, the atomic structures of light harvesting complexes and their macromolecular assemblies, the molecular mechanisms and dynamics of light harvesting and primary energy transformations, and the broad range of adaptations to different light environments. The book shows, using the example of the photosynthetic membrane, how complex biological structures utilize principles of chemistry and physics in order to carry out biological functions. The Photosynthetic Membrane: Molecular Mechanisms of Light Harvesting will appeal to a wide audience of undergraduate and postgraduate students as well as researchers working in the fields of biochemistry, molecular biology, biophysics, plant science and bioengineering.
Terje Aven Foundations of Risk Analysis Terje Aven Foundations of Risk Analysis Новинка

Terje Aven Foundations of Risk Analysis

6674.91 руб. или Купить в рассрочку!
Foundations of Risk Analysis presents the issues core to risk analysis – understanding what risk means, expressing risk, building risk models, addressing uncertainty, and applying probability models to real problems. The author provides the readers with the knowledge and basic thinking they require to successfully manage risk and uncertainty to support decision making. This updated edition reflects recent developments on risk and uncertainty concepts, representations and treatment. New material in Foundations of Risk Analysis includes: An up to date presentation of how to understand, define and describe risk based on research carried out in recent years. A new definition of the concept of vulnerability consistent with the understanding of risk. Reflections on the need for seeing beyond probabilities to measure/describe uncertainties. A presentation and discussion of a method for assessing the importance of assumptions (uncertainty factors) in the background knowledge that the subjective probabilities are based on A brief introduction to approaches that produce interval (imprecise) probabilities instead of exact probabilities. In addition the new version provides a number of other improvements, for example, concerning the use of cost-benefit analyses and the As Low As Reasonably Practicable (ALARP) principle. Foundations of Risk Analysis provides a framework for understanding, conducting and using risk analysis suitable for advanced undergraduates, graduates, analysts and researchers from statistics, engineering, finance, medicine and the physical sciences, as well as for managers facing decision making problems involving risk and uncertainty.
Stefan Schmidt R. Fusion Protein Technologies for Biopharmaceuticals. Applications and Challenges Stefan Schmidt R. Fusion Protein Technologies for Biopharmaceuticals. Applications and Challenges Новинка

Stefan Schmidt R. Fusion Protein Technologies for Biopharmaceuticals. Applications and Challenges

15728.87 руб. или Купить в рассрочку!
The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of the best-selling biologics worldwide. Enbrel® represents a milestone of modern therapies just as Humulin®, the first therapeutic recombinant protein for human use, approved by the FDA in 1982 and Orthoclone® the first monoclonal antibody reaching the market in 1986. These first generation molecules were soon followed by a plethora of recombinant copies of natural human proteins, and in 1998, the first de novo designed fusion protein was launched. Fusion Protein Technologies for Biopharmaceuticals examines the state of the art in developing fusion proteins for biopharmaceuticals, shedding light on the immense potential inherent in fusion protein design and functionality. A wide pantheon of international scientists and researchers deliver a comprehensive and complete overview of therapeutic fusion proteins, combining the success stories of marketed drugs with the dynamic preclinical and clinical research into novel drugs designed for as yet unmet medical needs. The book covers the major types of fusion proteins—receptor-traps, immunotoxins, Fc-fusions and peptibodies—while also detailing the approaches for developing, delivering, and improving the stability of fusion proteins. The main body of the book contains three large sections that address issues key to this specialty: strategies for extending the plasma half life, the design of toxic proteins, and utilizing fusion proteins for ultra specific targeting. The book concludes with novel concepts in this field, including examples of highly relevant multifunctional antibodies. Detailing the innovative science, commercial realities, and brilliant potential of fusion protein therapeutics, Fusion Protein Technologies for Biopharmaceuticals is a must for pharmaceutical scientists, biochemists, medicinal chemists, molecular biologists, pharmacologists, and genetic engineers interested in determining the shape of innovation in the world of biopharmaceuticals.
Thomas Luetteke Bioinformatics for Glycobiology and Glycomics. An Introduction Thomas Luetteke Bioinformatics for Glycobiology and Glycomics. An Introduction Новинка

Thomas Luetteke Bioinformatics for Glycobiology and Glycomics. An Introduction

15045.26 руб. или Купить в рассрочку!
This book is the first to be dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides an introduction to this emerging field of science both for the experimentalist working in glycobiology and glycomics, and also for the computer scientist looking for background information for the development of highly sophisticated algorithmic approaches. The book provides an overview of the state-of-the-art in the field, with reviews on databases, and the tools in use for analysis, interpretation, and prediction of the structures of complex carbohydrates, and demonstrates the value of bioinformatics for glycobiology. The availability of comprehensive databases and corresponding bioinformatics tools, to access and analyse the large amounts of experimental data relating to the structure of carbohydrates, will be a prerequisite for the success of the large-scale glycomics projects that aim to decipher new, so far unknown, biological functions of glycans. Efficient bioinformatics descriptions and tools can considerably enhance the efficiency of glycomics research, in terms of data quality, analysis and experimental costs. For a complete understanding of the molecular processes in which carbohydrates are involved, such as protein–carbohydrate interactions and the impact of glycosylation on protein function, knowledge of the 3D structure of the carbohydrate, the protein–carbohydrate complex, or the glycoprotein is often indispensable. This book provides a thorough introduction into methods used for conformational analysis of carbohydrates. Key features: Describes bioinformatic approaches to handle carbohydrate-active enzymes and glycosylation. Provides an overview on bioinformatics tools that facilitate analysis of carbohydrate structures. Gives introduction into molecular modelling of carbohydrate 3D structure and carbohydrates contained in the Protein Databank. Assumes only a basic knowledge of biology and bioinformatics.
Galit Shmueli Information Quality. The Potential of Data and Analytics to Generate Knowledge Galit Shmueli Information Quality. The Potential of Data and Analytics to Generate Knowledge Новинка

Galit Shmueli Information Quality. The Potential of Data and Analytics to Generate Knowledge

6840.46 руб. или Купить в рассрочку!
Provides an important framework for data analysts in assessing the quality of data and its potential to provide meaningful insights through analysis Analytics and statistical analysis have become pervasive topics, mainly due to the growing availability of data and analytic tools. Technology, however, fails to deliver insights with added value if the quality of the information it generates is not assured. Information Quality (InfoQ) is a tool developed by the authors to assess the potential of a dataset to achieve a goal of interest, using data analysis. Whether the information quality of a dataset is sufficient is of practical importance at many stages of the data analytics journey, from the pre-data collection stage to the post-data collection and post-analysis stages. It is also critical to various stakeholders: data collection agencies, analysts, data scientists, and management. This book: Explains how to integrate the notions of goal, data, analysis and utility that are the main building blocks of data analysis within any domain. Presents a framework for integrating domain knowledge with data analysis. Provides a combination of both methodological and practical aspects of data analysis. Discusses issues surrounding the implementation and integration of InfoQ in both academic programmes and business / industrial projects. Showcases numerous case studies in a variety of application areas such as education, healthcare, official statistics, risk management and marketing surveys. Presents a review of software tools from the InfoQ perspective along with example datasets on an accompanying website. This book will be beneficial for researchers in academia and in industry, analysts, consultants, and agencies that collect and analyse data as well as undergraduate and postgraduate courses involving data analysis.
Nabyla Daidj Cooperation, Coopetition and Innovation Nabyla Daidj Cooperation, Coopetition and Innovation Новинка

Nabyla Daidj Cooperation, Coopetition and Innovation

9120.61 руб. или Купить в рассрочку!
In presenting the concepts and the logical structure of the reasoning offered by game theory and their applications, the book explains the rational process of decision making in the framework of firm management and market competition. The book will expose both general teachings and a comprehensive analysis applied to specific case studies of various sectors of the economy.
Marina Lotti Protein Aggregation in Bacteria. Functional and Structural Properties of Inclusion Bodies in Bacterial Cells Marina Lotti Protein Aggregation in Bacteria. Functional and Structural Properties of Inclusion Bodies in Bacterial Cells Новинка

Marina Lotti Protein Aggregation in Bacteria. Functional and Structural Properties of Inclusion Bodies in Bacterial Cells

10180.65 руб. или Купить в рассрочку!
Focuses on the aggregation of recombinant proteins in bacterial cells in the form of inclusion bodies—and on their use in biotechnological and medical applications The first book devoted specifically to the topic of aggregation in bacteria, Protein Aggregation in Bacteria: Functional and Structural Properties of Inclusion Bodies in Bacterial Cells provides a large overview of protein folding and aggregation, including cell biology and methodological aspects. It summarizes, for the first time in one book, ideas and technical approaches that pave the way for a direct use of inclusion bodies in biotechnological and medical applications. Protein Aggregation in Bacteria covers: Molecular and cellular mechanisms of protein folding, aggregation, and disaggregation in bacteria Physiological importance and consequences of aggregation for the bacterial cell Factors inherent to the protein sequence responsible for aggregation and evolutionary mechanisms to keep proteins soluble Structural properties of proteins expressed as soluble aggregates and as inclusion bodies within bacterial cells both from a methodological point of view and with regard to their similarity with amyloids Control of the structural and functional properties of aggregated proteins and use thereof in biotechnology and medicine Protein Aggregation in Bacteria is ideal for researchers in protein science, biochemistry, bioengineering, biophysics, microbiology, medicine, and biotechnology, particularly if they are related with the production of recombinant proteins and pharmaceutical science.
Peter Ryan Environmental and Low Temperature Geochemistry Peter Ryan Environmental and Low Temperature Geochemistry Новинка

Peter Ryan Environmental and Low Temperature Geochemistry

11777.18 руб. или Купить в рассрочку!
Environmental and Low-Temperature Geochemistry presents conceptual and quantitative principles of geochemistry in order to foster understanding of natural processes at and near the earth’s surface, as well as anthropogenic impacts on the natural environment. It provides the reader with the essentials of concentration, speciation and reactivity of elements in soils, waters, sediments and air, drawing attention to both thermodynamic and kinetic controls. Specific features include: • An introductory chapter that reviews basic chemical principles applied to environmental and low-temperature geochemistry • Explanation and analysis of the importance of minerals in the environment • Principles of aqueous geochemistry • Organic compounds in the environment • The role of microbes in processes such as biomineralization, elemental speciation and reduction-oxidation reactions • Thorough coverage of the fundamentals of important geochemical cycles (C, N, P, S) • Atmospheric chemistry • Soil geochemistry • The roles of stable isotopes in environmental analysis • Radioactive and radiogenic isotopes as environmental tracers and environmental contaminants • Principles and examples of instrumental analysis in environmental geochemistry The text concludes with a case study of surface water and groundwater contamination that includes interactions and reactions of naturally-derived inorganic substances and introduced organic compounds (fuels and solvents), and illustrates the importance of interdisciplinary analysis in environmental geochemistry. Readership: Advanced undergraduate and graduate students studying environmental/low T geochemistry as part of an earth science, environmental science or related program. Additional resources for this book can be found at: www.wiley.com/go/ryan/geochemistry.
Vladimir Uversky Protein Oxidation and Aging Vladimir Uversky Protein Oxidation and Aging Новинка

Vladimir Uversky Protein Oxidation and Aging

12537.24 руб. или Купить в рассрочку!
Reviews our current understanding of the role of protein oxidation in aging and age-related diseases Protein oxidation is at the core of the aging process. Setting forth a variety of new methods and approaches, this book helps researchers conveniently by exploring the aging process and developing more effective therapies to prevent or treat age-related diseases. There have been many studies dedicated to the relationship between protein oxidation and age-related pathology; now it is possible for researchers and readers to learn new techniques as utilizing protein oxidation products as biomarkers for aging. Protein Oxidation and Aging begins with a description of the tremendous variety of protein oxidation products. Furthermore, it covers: Major aspects of the protein oxidation process Cellular mechanisms for managing oxidized proteins Role of protein oxidation in aging Influence of genetic and environmental factors on protein oxidation Measuring protein oxidation in the aging process Protein oxidation in age-related diseases References at the end of each chapter serve as a gateway to the growing body of original research studies and reviews in the field.
Vijay Thakur Kumar Handbook of Composites from Renewable Materials, Structure and Chemistry Vijay Thakur Kumar Handbook of Composites from Renewable Materials, Structure and Chemistry Новинка

Vijay Thakur Kumar Handbook of Composites from Renewable Materials, Structure and Chemistry

20902.12 руб. или Купить в рассрочку!
The Handbook of Composites From Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The handbook covers a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Together, the 8 volumes total at least 5000 pages and offers a unique publication. Volume 1 is solely focused on the Structure and Chemistry of renewable materials. Some of the important topics include but not limited to: carbon fibers from sustainable resources; polylactic acid composites and composite foams based on natural fibres; composites materials from other than cellulosic resources; microcrystalline cellulose and related polymer composites; tannin-based foam; renewable feedstock vanillin derived polymer and composites; silk biocomposites; bio-derived adhesives and matrix polymers; biomass based formaldehyde-free bio-resin ; isolation and characterization of water soluble polysaccharide; bio-based fillers; keratin based materials in biotechnology; structure of proteins adsorbed onto bioactive glasses for sustainable composite; effect of filler properties on the antioxidant response of starch composites; composite of chitosan and its derivate; magnetic biochar from discarded agricultural biomass; biodegradable polymers for protein and peptide conjugation; polyurethanes and polyurethane composites from bio-based / recycled components.
Se-Kwon Kim Marine Proteins and Peptides. Biological Activities and Applications Se-Kwon Kim Marine Proteins and Peptides. Biological Activities and Applications Новинка

Se-Kwon Kim Marine Proteins and Peptides. Biological Activities and Applications

20214.18 руб. или Купить в рассрочку!
Food proteins and bioactive peptides play a vital role in the growth and development of the body’s structural integrity and regulation, as well as having a variety of other functional properties. Land animal-derived food proteins such as collagen and gelatine carry risks of contamination (such as BSE). Marine-derived proteins, which can provide equivalents to collagen and gelatin without the associated risks, are becoming more popular among consumers because of their numerous health beneficial effects. Most marine-derived bioactive peptides are currently underutilized. While fish and shellfish are perhaps the most obvious sources of such proteins and peptides, there is also the potential for further development of proteins and peptides from sources like algae, sea cucumber and molluscs. Marine-derived proteins and peptides also have potential uses in novel products, with the possibility of wide commercialization in the food, beverage, pharmaceutical and cosmetic industries, as well as in other fields such as photography, textiles, leather, electronics, medicine and biotechnology. Marine Proteins and Peptides: Biological Activities and Applications presents an overview of the current status, future industrial perspectives and commercial trends of bioactive marine-derived proteins and peptides. Many of the industrial perspectives are drawn from the food industry, but the book also refers to the pharmaceutical and cosmetics industries. There have recently been significant advances in isolating functional ingredients from marine bio-resources and seafood by-products for use in these industries, but little has been published, creating a knowledge gap, particularly with regard to the isolation and purification processes. This book is the first to fill that gap. Marine Proteins and Peptides: Biological Activities and Applications is a valuable resource for researchers in marine biochemistry field as well as food industry managers interested in exploring novel techniques and knowledge on alternative food protein sources. It will become a standard reference book for researchers involved in developing marine bio-resources and seafood by-products for novel nutraceutical, cosmetics, and pharmaceutical applications. It will also appeal to managers and product developers in the food, pharmaceutical and cosmetics industries, particularly those looking to use marine-derived proteins and peptides as substitutes or replacements for unfashionable or outdated food components.
McCormick Norman J. Risk and Safety Analysis of Nuclear Systems McCormick Norman J. Risk and Safety Analysis of Nuclear Systems Новинка

McCormick Norman J. Risk and Safety Analysis of Nuclear Systems

10633.29 руб. или Купить в рассрочку!
The book has been developed in conjunction with NERS 462, a course offered every year to seniors and graduate students in the University of Michigan NERS program. The first half of the book covers the principles of risk analysis, the techniques used to develop and update a reliability data base, the reliability of multi-component systems, Markov methods used to analyze the unavailability of systems with repairs, fault trees and event trees used in probabilistic risk assessments (PRAs), and failure modes of systems. All of this material is general enough that it could be used in non-nuclear applications, although there is an emphasis placed on the analysis of nuclear systems. The second half of the book covers the safety analysis of nuclear energy systems, an analysis of major accidents and incidents that occurred in commercial nuclear plants, applications of PRA techniques to the safety analysis of nuclear power plants (focusing on a major PRA study for five nuclear power plants), practical PRA examples, and emerging techniques in the structure of dynamic event trees and fault trees that can provide a more realistic representation of complex sequences of events. The book concludes with a discussion on passive safety features of advanced nuclear energy systems under development and approaches taken for risk-informed regulations for nuclear plants.
Szabó Barna Introduction to Finite Element Analysis. Formulation, Verification and Validation Szabó Barna Introduction to Finite Element Analysis. Formulation, Verification and Validation Новинка

Szabó Barna Introduction to Finite Element Analysis. Formulation, Verification and Validation

9546.68 руб. или Купить в рассрочку!
When using numerical simulation to make a decision, how can its reliability be determined? What are the common pitfalls and mistakes when assessing the trustworthiness of computed information, and how can they be avoided? Whenever numerical simulation is employed in connection with engineering decision-making, there is an implied expectation of reliability: one cannot base decisions on computed information without believing that information is reliable enough to support those decisions. Using mathematical models to show the reliability of computer-generated information is an essential part of any modelling effort. Giving users of finite element analysis (FEA) software an introduction to verification and validation procedures, this book thoroughly covers the fundamentals of assuring reliability in numerical simulation. The renowned authors systematically guide readers through the basic theory and algorithmic structure of the finite element method, using helpful examples and exercises throughout. Delivers the tools needed to have a working knowledge of the finite element method Illustrates the concepts and procedures of verification and validation Explains the process of conceptualization supported by virtual experimentation Describes the convergence characteristics of the h-, p- and hp-methods Covers the hierarchic view of mathematical models and finite element spaces Uses examples and exercises which illustrate the techniques and procedures of quality assurance Ideal for mechanical and structural engineering students, practicing engineers and applied mathematicians Includes parameter-controlled examples of solved problems in a companion website (www.wiley.com/go/szabo)
Honghui Zhou ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins. Applications in Drug Discovery and Development Honghui Zhou ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins. Applications in Drug Discovery and Development Новинка

Honghui Zhou ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins. Applications in Drug Discovery and Development

11400.76 руб. или Купить в рассрочку!
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
Qipeng Guo Polymer Morphology. Principles, Characterization, and Processing Qipeng Guo Polymer Morphology. Principles, Characterization, and Processing Новинка

Qipeng Guo Polymer Morphology. Principles, Characterization, and Processing

14821.72 руб. или Купить в рассрочку!
With a focus on structure-property relationships, this book describes how polymer morphology affects properties and how scientists can modify them. The book covers structure development, theory, simulation, and processing; and discusses a broad range of techniques and methods. • Provides an up-to-date, comprehensive introduction to the principles and practices of polymer morphology • Illustrates major structure types, such as semicrystalline morphology, surface-induced polymer crystallization, phase separation, self-assembly, deformation, and surface topography • Covers a variety of polymers, such as homopolymers, block copolymers, polymer thin films, polymer blends, and polymer nanocomposites • Discusses a broad range of advanced and novel techniques and methods, like x-ray diffraction, thermal analysis, and electron microscopy and their applications in the morphology of polymer materials
Mackenzie Lynette Occupation Analysis in Practice Mackenzie Lynette Occupation Analysis in Practice Новинка

Mackenzie Lynette Occupation Analysis in Practice

4501.04 руб. или Купить в рассрочку!
Occupation Analysis in Practice is the essential book for all future and current occupational therapists. It offers a practical approach to the analysis of occupations in real world practice. The book frames occupation as the key component for analysis and builds upon previous work limited to analysis at the activity level. It examines the interests, goals, abilities and contexts of individuals, groups, institutions and communities, along with the demands of the occupation. It presents examples of occupation analysis in different practice context including working with children, health promotion, indigenous health, medico-legal practice; mental health and occupational rehabilitation. The book has four sections. Section 1 introduces theoretical perspectives of the concept of occupation analysis and how such analysis relates to particular models of Occupational Therapy practice and the generic World Health Organisation International Classification of Functioning, Disability and Health. Section 2 discusses analysis of particular components of occupation that support practice. These include culture, spirituality, home and community environments as well as self-care and leisure. Section 3 applies analysis of occupations to particular specialties encountered in practice. Section 4 considers the application of Occupation Analysis within professional reasoning and goal setting. FEATURES International team of contributors Examples of occupation analysis proforma Application to a wide range of practice areas. Glossary of key terms Incudes the International Classification of Functioning, Disability and Health.
Basel Abu-Jamous Integrative Cluster Analysis in Bioinformatics Basel Abu-Jamous Integrative Cluster Analysis in Bioinformatics Новинка

Basel Abu-Jamous Integrative Cluster Analysis in Bioinformatics

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Clustering techniques are increasingly being put to use in the analysis of high-throughput biological datasets. Novel computational techniques to analyse high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. This book details the complete pathway of cluster analysis, from the basics of molecular biology to the generation of biological knowledge. The book also presents the latest clustering methods and clustering validation, thereby offering the reader a comprehensive review of clustering analysis in bioinformatics from the fundamentals through to state-of-the-art techniques and applications. Key Features: Offers a contemporary review of clustering methods and applications in the field of bioinformatics, with particular emphasis on gene expression analysis Provides an excellent introduction to molecular biology with computer scientists and information engineering researchers in mind, laying out the basic biological knowledge behind the application of clustering analysis techniques in bioinformatics Explains the structure and properties of many types of high-throughput datasets commonly found in biological studies Discusses how clustering methods and their possible successors would be used to enhance the pace of biological discoveries in the future Includes a companion website hosting a selected collection of codes and links to publicly available datasets
Adam Grimes The Art and Science of Technical Analysis. Market Structure, Price Action and Trading Strategies Adam Grimes The Art and Science of Technical Analysis. Market Structure, Price Action and Trading Strategies Новинка

Adam Grimes The Art and Science of Technical Analysis. Market Structure, Price Action and Trading Strategies

6144.54 руб. или Купить в рассрочку!
A breakthrough trading book that provides powerful insights on profitable technical patterns and strategies The Art and Science of Technical Analysis is a groundbreaking work that bridges the gaps between the academic view of markets, technical analysis, and profitable trading. The book explores why randomness prevails in markets most, but not all, of the time and how technical analysis can be used to capture statistically validated patterns in certain types of market conditions. The belief of the book is that buying and selling pressure causes patterns in prices, but that these technical patterns are only effective in the presence of true buying/selling imbalance. The Art and Science of Technical Analysis is supported by extensive statistical analysis of the markets, which will debunk some tools and patterns such as Fibonacci analysis, and endorse other tools and trade setups. In addition, this reliable resource discusses trader psychology and trader learning curves based on the author's extensive experience as a trader and trainer of traders. Offers serious traders a way to think about market problems, understand their own performance, and help find a more productive path forward Includes extensive research to validate specific money-making patterns and strategies Written by an experienced market practitioner who has trained and worked with many top traders Filled with in-depth insights and practical advice, The Art and Science of Technical Analysis will give you a realistic sense of how markets behave, when and how technical analysis works, and what it really takes to trade successfully.
Marino Xanthos Functional Fillers for Plastics Marino Xanthos Functional Fillers for Plastics Новинка

Marino Xanthos Functional Fillers for Plastics

20257.59 руб. или Купить в рассрочку!
A comprehensive and up-to-date overview of the major mineral and organic fillers for plastics, their production, structure and properties, as well as their applications in terms of primary and secondary functions. Edited and co-authored by Professor Marino Xanthos with contributions by international experts from industry and academia, this book presents methods of mixing/incorporation technologies, surface treatments and modifications for enhanced functionality, an analysis of parameters affecting filler performance and a presentation of current and emerging applications. Additionally, the novel classification according to modification of specific polymer properties rather than filler chemical composition provides a better understanding of the relationships between processing, structure and properties of products containing functional fillers and the identification of new markets and applications. For engineers, scientists and technologists involved in the important sector of polymer composites.
Mohammed Khalid A.A. Pumps, Channels and Transporters. Methods of Functional Analysis Mohammed Khalid A.A. Pumps, Channels and Transporters. Methods of Functional Analysis Новинка

Mohammed Khalid A.A. Pumps, Channels and Transporters. Methods of Functional Analysis

9500.64 руб. или Купить в рассрочку!
Describes experimental methods for investigating the function of pumps, channels and transporters Covers new emerging analytical methods used to study ion transport membrane proteins such as single-molecule spectroscopy Details a wide range of electrophysiological techniques and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters Covers state-of-the art analytical methods to study ion pumps, channels, and transporters, and where analytical chemistry can make further contributions
Xiao-Ping Zhang Restructured Electric Power Systems. Analysis of Electricity Markets with Equilibrium Models Xiao-Ping Zhang Restructured Electric Power Systems. Analysis of Electricity Markets with Equilibrium Models Новинка

Xiao-Ping Zhang Restructured Electric Power Systems. Analysis of Electricity Markets with Equilibrium Models

8999.49 руб. или Купить в рассрочку!
The latest practical applications of electricity market equilibrium models in analyzing electricity markets Electricity market deregulation is driving the power energy production from a monopolistic structure into a competitive market environment. The development of electricity markets has necessitated the need to analyze market behavior and power. Restructured Electric Power Systems reviews the latest developments in electricity market equilibrium models and discusses the application of such models in the practical analysis and assessment of electricity markets. Drawing upon the extensive involvement in the research and industrial development of the leading experts in the subject area, the book starts by explaining the current developments of electrical power systems towards smart grids and then relates the operation and control technologies to the aspects in electricity markets. It explores: The problems of electricity market behavior and market power Mathematical programs with equilibrium constraints (MPEC) and equilibrium problems with equilibrium constraints (EPEC) Tools and techniques for solving the electricity market equilibrium problems Various electricity market equilibrium models State-of-the-art techniques for computing the electricity market equilibrium problems The application of electricity market equilibrium models in assessing the economic benefits of transmission expansions for market environments, forward and spot markets, short-term power system security, and analysis of reactive power impact Also featured are computational resources to allow readers to develop algorithms on their own, as well as future research directions in modeling and computational techniques in electricity market analysis. Restructured Electric Power Systems is an invaluable reference for electrical engineers and power system economists from power utilities and for professors, postgraduate students, and undergraduate students in electrical power engineering, as well as those responsible for the design, engineering, research, and development of competitive electricity markets and electricity market policy.
Anne Robinson Skaja Production of Membrane Proteins. Strategies for Expression and Isolation Anne Robinson Skaja Production of Membrane Proteins. Strategies for Expression and Isolation Новинка

Anne Robinson Skaja Production of Membrane Proteins. Strategies for Expression and Isolation

2169.35 руб. или Купить в рассрочку!
Designed as a research-level guide to current strategies and methods of membrane protein production on the small to intermediate scale, this practice-oriented book provides detailed, step-by-step laboratory protocols as well as an explanation of the principles behind each method, together with a discussion of its relative advantages and disadvantages. Following an introductory section on current challenges in membrane protein production, the book goes on to look at expression systems, emerging methods and approaches, and protein specific considerations. Case studies illustrate how to select or sample the optimal production system for any desired membrane protein, saving both time and money on the laboratory as well as the technical production scale. Unique in its coverage of «difficult» proteins with large membrane-embedded domains, proteins from extremophiles, peripheral membrane proteins, and protein fragments.
Sedat Tardu Transport and Coherent Structures in Wall Turbulence Sedat Tardu Transport and Coherent Structures in Wall Turbulence Новинка

Sedat Tardu Transport and Coherent Structures in Wall Turbulence

15596.79 руб. или Купить в рассрочку!
Wall bounded turbulent flows are of major importance in industrial and environmental fluid mechanics. The structure of the wall turbulence is intrinsically related to the coherent structures that play a fundamental role in the transport process. The comprehension of their regeneration mechanism is indispensable for the development of efficient strategies in terms of drag control and near wall turbulence management. This book provides an up-to-date overview on the progress made in this specific area in recent years.
Gary Hou G. Asian Noodles. Science, Technology, and Processing Gary Hou G. Asian Noodles. Science, Technology, and Processing Новинка

Gary Hou G. Asian Noodles. Science, Technology, and Processing

17861.2 руб. или Купить в рассрочку!
In Asian Noodles: Science, Technology and Processing, international experts review the current knowledge and offer comprehensive cutting-edge coverage on Asian noodles unmatchable in any publication. The authors cover an array of topics including breeding for noodle wheat, noodle flour milling, noodle flour quality control and analysis, noodle processing, sensory and instrumental measurements of noodle quality, the effects of wheat factors on noodle quality, packaging and storage, nutritional fortification of noodle products, noodle flavor seasoning, and noodle plant setup and management.
Karl Kropf The Handbook of Urban Morphology Karl Kropf The Handbook of Urban Morphology Новинка

Karl Kropf The Handbook of Urban Morphology

6080.41 руб. или Купить в рассрочку!
Conceived as a practical manual of morphological analysis, The Handbook of Urban Morphology focuses on the form, structure and evolution of human settlements – from villages to metropolitan regions. It is the first book in any language focused on specific, up-to-date ‘how-to’ guidance , with clear summaries of the central concepts, step-by-step instructions for carrying out the analysis, case studies illustrating specific applications and discussion of theoretical underpinnings tied to evidence from the field. Ideal for students as well as professionals and academics dealing with the built environment.
Cid Maria-Magdalena Structure Elucidation in Organic Chemistry. The Search for the Right Tools Cid Maria-Magdalena Structure Elucidation in Organic Chemistry. The Search for the Right Tools Новинка

Cid Maria-Magdalena Structure Elucidation in Organic Chemistry. The Search for the Right Tools

16454.44 руб. или Купить в рассрочку!
Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.
Jean-Louis Boulanger Static Analysis of Software. The Abstract Interpretation Jean-Louis Boulanger Static Analysis of Software. The Abstract Interpretation Новинка

Jean-Louis Boulanger Static Analysis of Software. The Abstract Interpretation

13893.14 руб. или Купить в рассрочку!
The existing literature currently available to students and researchers is very general, covering only the formal techniques of static analysis. This book presents real examples of the formal techniques called «abstract interpretation» currently being used in various industrial fields: railway, aeronautics, space, automotive, etc. The purpose of this book is to present students and researchers, in a single book, with the wealth of experience of people who are intrinsically involved in the realization and evaluation of software-based safety critical systems. As the authors are people currently working within the industry, the usual problems of confidentiality, which can occur with other books, is not an issue and so makes it possible to supply new useful information (photos, architectural plans, real examples).
Gary Hou G. Asian Noodles. Science, Technology, and Processing Gary Hou G. Asian Noodles. Science, Technology, and Processing Новинка

Gary Hou G. Asian Noodles. Science, Technology, and Processing

18239.59 руб. или Купить в рассрочку!
In Asian Noodles: Science, Technology and Processing, international experts review the current knowledge and offer comprehensive cutting-edge coverage on Asian noodles unmatchable in any publication. The authors cover an array of topics including breeding for noodle wheat, noodle flour milling, noodle flour quality control and analysis, noodle processing, sensory and instrumental measurements of noodle quality, the effects of wheat factors on noodle quality, packaging and storage, nutritional fortification of noodle products, noodle flavor seasoning, and noodle plant setup and management.

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A comprehensive guide to understanding, assessing, and responding to terrorism in this modern age This book provides readers with a thorough understanding of the types of attacks that may be perpetrated, and how to identify potential targets, conduct a meaningful vulnerability analysis, and apply protective measures to secure personnel and facilities. The new edition of Understanding, Assessing, and Responding to Terrorism updates existing material and includes several new topics that have emerged, including information on new international terrorist groups as well as a new chapter on Regulations and Standards. A vulnerability analysis methodology, consisting of several steps—which include the techniques necessary to conduct a vulnerability analysis—is introduced and applied through several sample scenarios. By using easily customized templates for the screening process, valuation of a critical asset as a target, vulnerability analysis, security procedures, emergency response procedures, and training programs, the book offers a practical step-by-step process to help reduce risk. Each different type of terrorism is briefly discussed—however, the book focuses on those potential attacks that may involve weapons of mass destruction. There is a discussion of what physical and administrative enhancements can be implemented to improve a facility's ability to devalue, detect, deter, deny, delay, defend, respond, and recover to a real or threatened terrorist attack—whether it be at a facility, or in the community. Techniques on how personnel safety and security can be improved through the implementation of counter-terrorism programs are also outlined. An overview of the major counter-terrorism regulations and standards are presented, along with the significant governmental efforts that have been implemented to help prevent terrorist attacks and foster preparedness at both private and public sector facilities and for personnel. Understanding, Assessing, and Responding to Terrorism, Second Edition: Updates existing material, plus includes several new topics that have emerged including information on new international terrorist groups, new terrorist tactics, cyber terrorism, and Regulations and Standards Outlines techniques for improving facility and personnel safety and security through the implementation of counter-terrorism programs Unites the emergency response/public sector community with the private sector over infrastructure protection, thus allowing for easier communication between them Includes questions/exercises at the end of each chapter and a solutions manual to facilitate its use as a textbook Understanding, Assessing, and Responding to Terrorism, Second Edition is a must-have reference for private and public sector risk managers, safety engineers, security professionals, facility managers, emergency responders, and others charged with protecting facilities and personnel from all types of hazards (accidental, intentional, and natural).
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